KEGG   ORTHOLOGY: K11185
Entry
K11185                      KO                                     

Name
TRYP
Definition
cytosolic tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin [EC:1.11.1.-]
Pathway
ko00480  Glutathione metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    K11185  TRYP; cytosolic tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.-  
     K11185  TRYP; cytosolic tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin
Other DBs
RN: R08360 R08362
GO: 0051920
Genes
TBR: Tb09.160.4250 Tb09.160.4280
TBG: TbgDal_IX3050
TCR: 487507.10 504839.28 504839.44 505983.9 507259.10 509445.10
LMA: LMJF_15_1040(TRYP1) LMJF_15_1060(TRYP2) LMJF_15_1080(TRYP3) LMJF_15_1100(TRYP4) LMJF_15_1120(TRYP5) LMJF_15_1140(TRYP6) LMJF_15_1160(TRYP7)
LIF: LINJ_15_1100(TRYP) LINJ_15_1120(TRYP) LINJ_15_1140(TRYP)
LDO: LDBPK_151140
LMI: LMXM_15_1160
LBZ: LBRM_15_1080(TRYP1) LBRM_15_1100
LPAN: LPMP_151070
Reference
  Authors
Krauth-Siegel RL, Meiering SK, Schmidt H.
  Title
The parasite-specific trypanothione metabolism of trypanosoma and leishmania.
  Journal
Biol Chem 384:539-49 (2003)
DOI:10.1515/BC.2003.062
LinkDB

KEGG   ORTHOLOGY: K11186
Entry
K11186                      KO                                     

Name
MTRYP
Definition
mitochondrial tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin [EC:1.11.1.-]
Pathway
ko00480  Glutathione metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    K11186  MTRYP; mitochondrial tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.-  
     K11186  MTRYP; mitochondrial tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin
Other DBs
RN: R08360 R08362
GO: 0051920
Genes
TBR: Tb927.8.1990
TBG: TbgDal_VIII1645
TCR: 509499.14
LMA: LMJF_23_0040
LIF: LINJ_23_0050
LDO: LDBPK_230050
LMI: LMXM_23_0040
LBZ: LBRM_23_0050
LPAN: LPMP_230050
Reference
  Authors
Krauth-Siegel RL, Meiering SK, Schmidt H.
  Title
The parasite-specific trypanothione metabolism of trypanosoma and leishmania.
  Journal
Biol Chem 384:539-49 (2003)
DOI:10.1515/BC.2003.062
LinkDB

KEGG   REACTION: R08362
Entry
R08362                      Reaction                               

Name
trypanothione:hydroperoxide oxidoreductase
Definition
Trypanothione + ROOH <=> Trypanothione disulfide + H2O + ROH
Equation
Reaction class
RC01003  C02090_C03170
RC01872  C01335_C15498
Enzyme
1.11.1.-
Pathway
rn00480  Glutathione metabolism
Orthology
K11185  cytosolic tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin [EC:1.11.1.-]
K11186  mitochondrial tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin [EC:1.11.1.-]
LinkDB

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