KEGG   ORTHOLOGY: K11207
Entry
K11207                      KO                                     

Name
TDPX
Definition
glutathione peroxidase-type tryparedoxin peroxidase [EC:1.11.1.-]
Pathway
ko00480  Glutathione metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    K11207  TDPX; glutathione peroxidase-type tryparedoxin peroxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.-  
     K11207  TDPX; glutathione peroxidase-type tryparedoxin peroxidase
Other DBs
RN: R08360
Genes
TBR: Tb927.7.1120 Tb927.7.1130 Tb927.7.1140
TBG: TbgDal_VII1090 TbgDal_VII1100
TCR: 503899.110 503899.119 503899.130 507515.10
LMA: LMJF_26_0800(TDPX) LMJF_26_0810(TDPX) LMJF_26_0820(TDPX)
LIF: LINJ_26_0770 LINJ_26_0780
LDO: LDBPK_260780
LMI: LMXM_26_0800 LMXM_26_0810
LBZ: LBRM_26_0820 LBRM_26_0830
LPAN: LPMP_260790
Reference
PMID:17922848 (L.major)
  Authors
Konig J, Fairlamb AH.
  Title
A comparative study of type I and type II tryparedoxin peroxidases in Leishmania major.
  Journal
FEBS J 274:5643-58 (2007)
DOI:10.1111/j.1742-4658.2007.06087.x
Reference
PMID:12466271 (T.brucei)
  Authors
Hillebrand H, Schmidt A, Krauth-Siegel RL.
  Title
A second class of peroxidases linked to the trypanothione metabolism.
  Journal
J Biol Chem 278:6809-15 (2003)
DOI:10.1074/jbc.M210392200
  Sequence
LinkDB

KEGG   REACTION: R08360
Entry
R08360                      Reaction                               

Name
tryparedoxin:hydroperoxide oxidoreductase
Definition
Tryparedoxin + ROOH <=> Tryparedoxin disulfide + H2O + ROH
Equation
Reaction class
RC01872  C01335_C15498
Enzyme
1.11.1.-
Pathway
rn00480  Glutathione metabolism
rn01100  Metabolic pathways
Orthology
K11185  cytosolic tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin [EC:1.11.1.-]
K11186  mitochondrial tryparedoxin peroxidase, trypanosomatid typical 2-Cys peroxiredoxin [EC:1.11.1.-]
K11207  glutathione peroxidase-type tryparedoxin peroxidase [EC:1.11.1.-]
LinkDB

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