KEGG   ORTHOLOGY: K11220
Entry
K11220                      KO                                     

Name
STAT1
Definition
signal transducer and activator of transcription 1
Pathway
ko04062  Chemokine signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04630  JAK-STAT signaling pathway
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04917  Prolactin signaling pathway
ko04919  Thyroid hormone signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko04935  Growth hormone synthesis, secretion and action
ko05140  Leishmaniasis
ko05145  Toxoplasmosis
ko05152  Tuberculosis
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
ko05212  Pancreatic cancer
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
H01109  Chronic mucocutaneous candidiasis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11220  STAT1; signal transducer and activator of transcription 1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04621 NOD-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04625 C-type lectin receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04658 Th1 and Th2 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04659 Th17 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04062 Chemokine signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04935 Growth hormone synthesis, secretion and action
    K11220  STAT1; signal transducer and activator of transcription 1
   04919 Thyroid hormone signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K11220  STAT1; signal transducer and activator of transcription 1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11220  STAT1; signal transducer and activator of transcription 1
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K11220  STAT1; signal transducer and activator of transcription 1
  09172 Infectious disease: viral
   05161 Hepatitis B
    K11220  STAT1; signal transducer and activator of transcription 1
   05160 Hepatitis C
    K11220  STAT1; signal transducer and activator of transcription 1
   05171 Coronavirus disease - COVID-19
    K11220  STAT1; signal transducer and activator of transcription 1
   05164 Influenza A
    K11220  STAT1; signal transducer and activator of transcription 1
   05162 Measles
    K11220  STAT1; signal transducer and activator of transcription 1
   05168 Herpes simplex virus 1 infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05169 Epstein-Barr virus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05165 Human papillomavirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K11220  STAT1; signal transducer and activator of transcription 1
   05140 Leishmaniasis
    K11220  STAT1; signal transducer and activator of transcription 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11220  STAT1; signal transducer and activator of transcription 1
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11220  STAT1; signal transducer and activator of transcription 1
Genes
HSA: 6772(STAT1)
PTR: 459834(STAT1)
PPS: 100971620(STAT1)
GGO: 101131770(STAT1)
PON: 100173683(STAT1)
NLE: 100596344(STAT1)
MCC: 693650(STAT1)
MCF: 101925134(STAT1)
CSAB: 103217529(STAT1)
RRO: 104675282(STAT1)
RBB: 108527866(STAT1)
CJC: 100401630(STAT1)
SBQ: 101030811(STAT1)
MMU: 20846(Stat1)
MCAL: 110304843(Stat1)
MPAH: 110321139(Stat1)
RNO: 25124(Stat1)
MUN: 110552020(Stat1)
CGE: 100755609(Stat1)
NGI: 103736156(Stat1)
HGL: 101718902(Stat1)
CCAN: 109679865 109682738(Stat1)
OCU: 100343893(STAT1)
TUP: 102476590(STAT1)
CFA: 488449(STAT1)
VVP: 112922923(STAT1)
AML: 100474026(STAT1)
UMR: 103659933(STAT1)
UAH: 113250654(STAT1)
ORO: 101378785(STAT1)
ELK: 111144592
FCA: 101084561(STAT1)
PTG: 102953174(STAT1)
PPAD: 109274693(STAT1)
AJU: 106979712(STAT1)
BTA: 510814(STAT1)
BOM: 102283508(STAT1)
BIU: 109568771(STAT1)
BBUB: 102415500(STAT1)
CHX: 102189170(STAT1)
OAS: 100307049(STAT1)
SSC: 396655(STAT1)
CFR: 102509999(STAT1)
CDK: 105088783(STAT1)
BACU: 103013781
LVE: 103069117
OOR: 101272458(STAT1)
DLE: 111171663(STAT1)
PCAD: 102977655(STAT1)
ECB: 100069633(STAT1)
EPZ: 103548655(STAT1)
EAI: 106828796(STAT1)
MYB: 102243651(STAT1)
MYD: 102757059(STAT1)
MNA: 107540521(STAT1)
HAI: 109393276(STAT1)
DRO: 112307780(STAT1)
PALE: 102886603(STAT1)
RAY: 107519182(STAT1)
MJV: 108400080(STAT1)
LAV: 100668424(STAT1)
TMU: 101357916
MDO: 100028917(STAT1)
SHR: 105749862(STAT1)
PCW: 110213248(STAT1)
OAA: 100087266(STAT1)
GGA: 424044(STAT1)
MGP: 100544816(STAT1)
CJO: 107316322(STAT1)
NMEL: 110399457(STAT1)
APLA: 101795022(STAT1)
ACYG: 106039967(STAT1)
TGU: 100221342(STAT1)
LSR: 110471109(STAT1)
SCAN: 103814539(STAT1)
GFR: 102036007(STAT1)
FAB: 101811260(STAT1)
PHI: 102100816(STAT1)
PMAJ: 107207405(STAT1)
CCAE: 111931930(STAT1)
CCW: 104693738(STAT1)
ETL: 114057449(STAT1)
FPG: 101922205(STAT1)
FCH: 102054689(STAT1)
CLV: 102098106(STAT1)
EGZ: 104130544(STAT1)
NNI: 104014274(STAT1)
ACUN: 113482458(STAT1)
PADL: 103925472(STAT1)
AAM: 106492439(STAT1)
ASN: 102374439(STAT1)
AMJ: 102571738(STAT1)
PSS: 102462741(STAT1)
CMY: 102934663
CPIC: 101931440(STAT1)
ACS: 100558595(stat1)
PVT: 110083952(STAT1)
PBI: 103060112(STAT1)
PMUR: 107289220(STAT1)
TSR: 106537889(STAT1)
PMUA: 114607449(STAT1)
XLA: 108703082 398324(stat1.L)
XTR: 780397(stat1)
NPR: 108798858(STAT1)
DRE: 30768(stat1a) 368481(stat1b)
IPU: 108259490 108266311(STAT1)
EEE: 113581352(stat1) 113586831
TRU: 101068828(stat1) 101079646
NCC: 104949635
MZE: 101476764(stat1) 101486905
ONL: 100696359(stat1) 100709564
PRET: 103457785(stat1) 103460709
CVG: 107080778 107092284(stat1)
NFU: 107384662(stat1) 107397172
KMR: 108229342(stat1) 108250770
ALIM: 106531438(stat1)
CSEM: 103389515(stat1) 103392403
SDU: 111218101 111222701(stat1)
HCQ: 109517578 109520194(stat1)
MALB: 109955685(stat1)
SASA: 100136558(STAT1) 106586142
PKI: 111842948 111845415(stat1)
LCM: 102353760(STAT1)
CMK: 103176541(stat1)
RTP: 109920367(stat1)
 » show all
Reference
PMID:1502203
  Authors
Schindler C, Fu XY, Improta T, Aebersold R, Darnell JE Jr
  Title
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
  Journal
Proc Natl Acad Sci U S A 89:7836-9 (1992)
DOI:10.1073/pnas.89.16.7836
  Sequence
[hsa:6772]
LinkDB

KEGG   ORTHOLOGY: K11221
Entry
K11221                      KO                                     

Name
STAT2
Definition
signal transducer and activator of transcription 2
Pathway
ko04062  Chemokine signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04621  NOD-like receptor signaling pathway
ko04625  C-type lectin receptor signaling pathway
ko04630  JAK-STAT signaling pathway
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05162  Measles
ko05164  Influenza A
ko05165  Human papillomavirus infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
ko05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11221  STAT2; signal transducer and activator of transcription 2
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
   04625 C-type lectin receptor signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
   04062 Chemokine signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K11221  STAT2; signal transducer and activator of transcription 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11221  STAT2; signal transducer and activator of transcription 2
  09172 Infectious disease: viral
   05161 Hepatitis B
    K11221  STAT2; signal transducer and activator of transcription 2
   05160 Hepatitis C
    K11221  STAT2; signal transducer and activator of transcription 2
   05171 Coronavirus disease - COVID-19
    K11221  STAT2; signal transducer and activator of transcription 2
   05164 Influenza A
    K11221  STAT2; signal transducer and activator of transcription 2
   05162 Measles
    K11221  STAT2; signal transducer and activator of transcription 2
   05168 Herpes simplex virus 1 infection
    K11221  STAT2; signal transducer and activator of transcription 2
   05167 Kaposi sarcoma-associated herpesvirus infection
    K11221  STAT2; signal transducer and activator of transcription 2
   05169 Epstein-Barr virus infection
    K11221  STAT2; signal transducer and activator of transcription 2
   05165 Human papillomavirus infection
    K11221  STAT2; signal transducer and activator of transcription 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11221  STAT2; signal transducer and activator of transcription 2
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11221  STAT2; signal transducer and activator of transcription 2
Genes
HSA: 6773(STAT2)
PTR: 451996(STAT2)
PPS: 100972085(STAT2)
GGO: 101146695(STAT2)
PON: 100452011(STAT2)
NLE: 100585171(STAT2)
MCC: 712694(STAT2)
MCF: 102133020(STAT2)
CSAB: 103238525(STAT2)
RRO: 104673676(STAT2)
RBB: 108516059(STAT2)
CJC: 100393190(STAT2)
SBQ: 101029836(STAT2)
MMU: 20847(Stat2)
MCAL: 110302854(Stat2)
MPAH: 110326622(Stat2)
RNO: 288774(Stat2)
MUN: 110559388(Stat2)
CGE: 100764772(Stat2)
NGI: 103746519(Stat2)
HGL: 101707295(Stat2)
CCAN: 109686120(Stat2)
OCU: 100344467(STAT2)
TUP: 102477989(STAT2)
CFA: 481111(STAT2)
VVP: 112922378(STAT2)
AML: 100472167(STAT2)
UMR: 103656206(STAT2)
UAH: 113256419(STAT2)
ORO: 101368050(STAT2)
ELK: 111160141
FCA: 101099224(STAT2)
PTG: 102967399(STAT2)
PPAD: 109270329(STAT2)
AJU: 106986878(STAT2)
BTA: 511023(STAT2)
BOM: 102277710(STAT2)
BIU: 109559357(STAT2)
BBUB: 102414314(STAT2)
CHX: 102190301(STAT2)
OAS: 101108211(STAT2)
SSC: 396923(STAT2)
CFR: 102510903(STAT2)
CDK: 105086362(STAT2)
BACU: 103000458(STAT2)
LVE: 103081732(STAT2)
OOR: 101281591(STAT2)
DLE: 111173869(STAT2)
PCAD: 102981574(STAT2)
ECB: 100052513(STAT2)
EPZ: 103557548(STAT2)
EAI: 106832955(STAT2)
MYB: 102240965(STAT2)
MYD: 102766233(STAT2)
MNA: 107546189(STAT2)
HAI: 109396910(STAT2)
DRO: 112319116(STAT2)
PALE: 102879640(STAT2)
RAY: 107521231(STAT2)
MJV: 108402236(STAT2)
LAV: 100656374(STAT2)
TMU: 101348948
SHR: 100933167(STAT2)
PCW: 110210934(STAT2)
OAA: 100087549(STAT2)
GGA: 100858732(STAT2)
MGP: 104916177(STAT2)
CJO: 107325845(STAT2)
NMEL: 110389141(STAT2)
TGU: 105760310
LSR: 110477089(STAT2)
PHI: 102112270(STAT2)
ETL: 114070775(STAT2)
FPG: 101912561(STAT2)
FCH: 106630923(STAT2)
ASN: 106721797(STAT2)
AMJ: 102574603(STAT2)
CPIC: 101944167(STAT2)
ACS: 103277767(stat2)
PVT: 110074594(STAT2)
PBI: 103065958(STAT2)
PMUR: 107290900(STAT2)
TSR: 106544441(STAT2)
PMUA: 114586539(STAT2)
GJA: 107126172(STAT2)
XLA: 108708573(stat2.L) 108709841(stat2.S)
XTR: 100170174(stat2)
NPR: 108791510
DRE: 565200(stat2)
CCAR: 109081275
IPU: 108272207
PHYP: 113545874
AMEX: 103021407
EEE: 113567990
TRU: 101071462
LCO: 104931961
NCC: 104966838
MZE: 101479682
ONL: 100701534
OLA: 101173855
XMA: 102236235
XCO: 114135114
PRET: 103465382
CVG: 107082130
NFU: 107385678
KMR: 108235753
ALIM: 106518034(stat2)
AOCE: 111566617
CSEM: 103385958
POV: 109629253
LCF: 108881447
SDU: 111221460
SLAL: 111667811
HCQ: 109522346
BPEC: 110168365
MALB: 109956049
SASA: 100270812(stat2)
OTW: 112217577
SALP: 111966796
ELS: 105017162
SFM: 108918442
PKI: 111854344
LCM: 102355078(STAT2)
CMK: 103191066
 » show all
Reference
PMID:1502204
  Authors
Fu XY, Schindler C, Improta T, Aebersold R, Darnell JE Jr
  Title
The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction.
  Journal
Proc Natl Acad Sci U S A 89:7840-3 (1992)
DOI:10.1073/pnas.89.16.7840
  Sequence
[hsa:6773]
LinkDB

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