KEGG   ORTHOLOGY: K11263
Entry
K11263                      KO                                     

Name
bccA, pccA
Definition
acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Pathway
ko00061  Fatty acid biosynthesis
ko00280  Valine, leucine and isoleucine degradation
ko00620  Pyruvate metabolism
ko00630  Glyoxylate and dicarboxylate metabolism
ko00640  Propanoate metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
ko01212  Fatty acid metabolism
Module
M00082  Fatty acid biosynthesis, initiation
M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K11263  bccA, pccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein
   00630 Glyoxylate and dicarboxylate metabolism
    K11263  bccA, pccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein
   00640 Propanoate metabolism
    K11263  bccA, pccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K11263  bccA, pccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K11263  bccA, pccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     K11263  bccA, pccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     K11263  bccA, pccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein
    6.4.1.3  propionyl-CoA carboxylase
     K11263  bccA, pccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein
Other DBs
RN: R00742 R01859 R04385
COG: COG4770
GO: 0003989 0004658 0004075
Genes
KPV: KPNIH29_27195
KMI: VW41_06490
EBT: EBL_c28340
CNT: JT31_18820
CEM: LH23_22100
CLAP: NCTC11466_01217(accC_2)
PGE: LG71_07750
BUF: D8682_20720
IZH: FEM41_17735
DDA: Dd703_3292
PLU: plu4306
PAY: PAU_00440
PMR: PMI3559
PHAU: PH4a_09195
XBO: XBJ1_0532(accA)
XBV: XBW1_0450(bccA)
XNE: XNC1_0633(accA)
XNM: XNC2_0619(accA)
XDO: XDD1_3596(bccA)
XPO: XPG1_3049(bccA)
PSI: S70_02000
PSX: DR96_3563
PRG: RB151_026280(accC_1)
PHEI: NCTC12003_01599(accC_1)
PRJ: NCTC6933_02292(accC_1)
PPSE: BN5_3751(accC3)
PSB: Psyr_0500
PSYR: N018_23615
PVD: CFBP1590__3636(bccA)
PSES: PSCI_2274
PSIL: PMA3_18535
ACB: A1S_1270
ABM: ABSDF2255(bccA)
ABY: ABAYE2438(bccA)
ABN: AB57_1456
ABB: ABBFA_02231(accC_2)
ABX: ABK1_1719
ABH: M3Q_1642
ABAD: ABD1_12950(bccA)
ABAZ: P795_11070
ABAU: IX87_04095
ABAA: IX88_08520
ACC: BDGL_000602(bccA)
ACI: ACIAD2517(bccA)
AGU: AS4_04720
SALN: SALB1_1111
REH: H16_B1757(h16_B1757)
CNC: CNE_2c17010(bccA)
CGD: CR3_3800(bccA)
PLG: NCTC10937_00265(accC_1)
LMIR: NCTC12852_02435(accC_2)
ODI: ODI_R3843
RFR: Rfer_0868
AAV: Aave_3510
AAA: Acav_3400
DAC: Daci_5726
CTES: O987_03110
HPSE: HPF_13085(accA5)
SMI: BN406_06793(bccA)
RHI: NGR_b19600(accC1)
SFD: USDA257_c17430(bccA1) USDA257_c17780(bccA2) USDA257_c25160(bccA3)
SAME: SAMCFNEI73_pC1575(bccA)
ATU: Atu3913
ARA: Arad_8585(accCch)
AVI: Avi_5845
RIR: BN877_II0986(bccA)
NEN: NCHU2750_50100(bccA)
SHZ: shn_23760
PDE: Pden_0323
PAMN: pAMV3p0048
KVU: EIO_2526
KRO: BVG79_p1000194(bccA)
MALG: MALG_03733
RID: RIdsm_05457(accA1_5)
SMAZ: LH19_27150
SGI: SGRAN_0496(accC)
SPHM: G432_00750
SPKC: KC8_01910
MTU: Rv2501c(accA1) Rv3285(accA3)
MTC: MT2576(bccA-2) MT3384(bccA-3)
MRA: MRA_2527(accA1) MRA_3326(accA3)
MTUR: CFBS_2650(accA1) CFBS_3476(accA3)
MTO: MTCTRI2_2547(accA1) MTCTRI2_3352(accA3)
MTD: UDA_2501c(accA1) UDA_3285(accA3)
MTN: ERDMAN_2751(accA1) ERDMAN_3601(accA3)
MTUC: J113_22935
MTUH: I917_17650
MTUT: HKBT1_2641(accA1) HKBT1_3463(accA3)
MTUU: HKBT2_2644(accA1) HKBT2_3470(accA3)
MTQ: HKBS1_2648(accA1) HKBS1_3473(accA3)
MBO: BQ2027_MB2529C(accA1) BQ2027_MB3313(accA3)
MBB: BCG_2521c(accA1) BCG_3314(accA3)
MBT: JTY_2515(accA1) JTY_3310(accA3)
MBM: BCGMEX_2513c(accA1) BCGMEX_3312(accA3)
MAF: MAF_25160(accA1) MAF_32960(accA3)
MCE: MCAN_25401(accA1) MCAN_33081(accA3)
MCQ: BN44_50492(accA) BN44_70076(accA)
MCV: BN43_40167(accA) BN43_60300(accA)
MCX: BN42_40457(accA) BN42_41343(accA)
MCZ: BN45_50885(accA) BN45_60323(accA)
MLE: ML0726(bccA)
MLB: MLBr00726(bccA)
MPA: MAP_2313c(accA1) MAP_3404(accA3)
MLP: MLM_3415
MUL: MUL_2637(accA3) MUL_3779(accA1)
MMI: MMAR_1251(accA3) MMAR_3848(accA1)
MMAE: MMARE11_12190(accA3) MMARE11_37340(accA1)
MLI: MULP_01411(accA3) MULP_04094(accA1)
MSHG: MSG_01150 MSG_03513(accA1)
MFJ: MFLOJ_22360(accA3) MFLOJ_51820(accA1)
MXE: MYXE_17670 MYXE_37390(accA3)
MNV: MNVI_02200 MNVI_27890(accA3)
MSG: MSMEI_1762(accA3) MSMEI_4599
MPHL: MPHLCCUG_01582(accA1_2) MPHLCCUG_03666(accA1_3)
MTHN: 4412656_01168(accC_2) 4412656_02959(accA1_2)
MHAS: MHAS_00484(accA1_1) MHAS_01110(accA1_2)
MAUU: NCTC10437_01367(accA1_1) NCTC10437_03837(accA1_2)
MSAL: DSM43276_03438(accC) DSM43276_04380(accA1_2)
MJD: JDM601_1404(accA1) JDM601_3045(accA3)
MTER: 4434518_01297(accA1_1) 4434518_03035(accC)
MMIN: MMIN_07760 MMIN_29980(accA1)
MHIB: MHIB_08600(accA1) MHIB_24850
ASD: AS9A_3838 AS9A_4352(accA)
CGL: NCgl0670(Cgl0700)
CGB: cg0802(accBC)
CGU: WA5_0670(AccBC)
CGT: cgR_0820
CGM: cgp_0802(accBC)
CGJ: AR0_04090
CEF: CE0719(accBC)
CDI: DIP0649(accBC)
CDP: CD241_0589(accBC)
CDH: CDB402_0564(accBC)
CDT: CDHC01_0589(accBC)
CDE: CDHC02_0595(accBC)
CDR: CDHC03_0574(accBC)
CDA: CDHC04_0556(accBC)
CDZ: CD31A_0652(accBC)
CDB: CDBH8_0607(accBC)
CDS: CDC7B_0602(accBC)
CDD: CDCE8392_0597(accBC)
CDW: CDPW8_0649(accBC)
CDV: CDVA01_0537(accBC)
CDIP: ERS451417_00582(accBC)
CJK: jk0405(accBC3) jk1550(accBC1) jk1669(accBC2)
CUR: cu0446(accBC1) cu1579(accBC2)
CUA: CU7111_0439(accBC1) CU7111_1522(accBC2)
CAR: cauri_0555(accBC1) cauri_0590(accBC2)
CKP: ckrop_1542(accBC)
CPL: Cp3995_0484(accBC)
CPP: CpP54B96_0483(accBC)
CPZ: CpPAT10_0481(accBC)
COR: Cp267_0497(accBC)
COD: Cp106_0467(accBC)
COS: Cp4202_0471(accBC)
CPSE: CPTA_01023
CPSU: CPTB_00510
CPSF: CPTC_00170
CRD: CRES_0734(accBC3) CRES_1679(accBC1) CRES_1759(accBC2)
CUL: CULC22_00532(accBC)
CUC: CULC809_00525(accBC)
CUE: CULC0102_0635(accBC)
CUN: Cul210932_0552(accBC)
CUS: CulFRC11_0528(accBC)
CUQ: Cul210931_0531(accBC)
CUZ: Cul05146_0567(accBC)
CUJ: CUL131002_0533c(accBC)
CVA: CVAR_0607(accBC3) CVAR_2091 CVAR_2208(accBC1) CVAR_2518(accBC2)
CGY: CGLY_02510(bccA1) CGLY_04385(bccA2) CGLY_12885(bccA3)
COA: DR71_1562(accA1) DR71_624
CSX: CSING_03040(bccA1) CSING_03230(bccA2)
CMQ: B840_02545(bccA2) B840_04685(bccA1)
CKU: UL82_02255(bccA)
CMV: CMUST_03545(bccA)
CEI: CEPID_02900(bccA) CEPID_03910(accA1)
CDX: CDES_03545(bccA)
CPHO: CPHO_09795
CGV: CGLAU_02645(accA1)
CAQU: CAQU_02660
CMIN: NCTC10288_01952(accBC2) NCTC10288_01994(accBC1)
CPEG: CPELA_08545(accC2)
CEE: CENDO_02575(accC) CENDO_09540(cfiB2)
CGK: CGERO_02540(accC)
NFR: ERS450000_03127(accA1_1) ERS450000_04853(accA1_3)
NAD: NCTC11293_01839(accA1_2) NCTC11293_06425(accA1_4)
RER: RER_18310(accA) RER_21210(accA)
ROP: ROP_31190(accA) ROP_35620(accA) ROP_61530(accA) ROP_63450(accA)
REQ: REQ_33920(accA) REQ_36030(accA)
RFA: A3L23_00076(accC_1) A3L23_00378(accC_2) A3L23_02159(accA1_1)
RHS: A3Q41_01219(accA1_2) A3Q41_03030(accC_2) A3Q41_03337(accC_3)
RHU: A3Q40_00065(accA1_1) A3Q40_02064(accC_1)
RRT: 4535765_03381(accA1_2) 4535765_04752(accC1)
RCR: NCTC10994_02777(accC1) NCTC10994_03879(accA1_4)
GRU: GCWB2_06960(accA2) GCWB2_08985(accA3)
GOM: D7316_01437(accA1_2) D7316_01864(accA1_3)
SRT: Srot_0519
SCO: SCO2777(accC) SCO4921(accA2) SCO6271(accA1)
SMA: SAVERM_3337(accA3) SAVERM_5277(accA1)
SCB: SCAB_34621(accA2) SCAB_58021(accC)
SCT: SCAT_1855(accA) SCAT_3815(bccA)
SDV: BN159_3476(bccA) BN159_5501(accA1)
SLV: SLIV_06790(bccA1) SLIV_13770(bccA2) SLIV_23790(accA1)
SGU: SGLAU_12665(accA1) SGLAU_21205(bccA)
SAMB: SAM23877_2812(accA) SAM23877_4742(bccA)
SRW: TUE45_03392(accA1_1) TUE45_05465(accC)
SLE: sle_27560(sle_27560) sle_44630(sle_44630)
SRN: A4G23_01829(accA1_1) A4G23_03612(accC)
SALJ: SMD11_2577(bccA) SMD11_4400(bccA) SMD11_6038(bccA)
SLX: SLAV_14935(accC) SLAV_23950(accA2)
SGE: DWG14_03180(accC) DWG14_05331(accA1_2)
KSK: KSE_26830(accA) KSE_29850
TWH: TWT_020(bccA)
TWS: TW020
LXX: Lxx04730(accC)
CMI: CMM_0991(accA)
CMS: CMS0609(accC)
CMC: CMN_00954(accA)
MTS: MTES_0597(accC) MTES_1634
MOO: BWL13_00349(accA1) BWL13_02218(accC)
MLV: CVS47_00722(accC) CVS47_01277(accA1_2)
MOY: CVS54_00513(accC_1) CVS54_01254(accC_2) CVS54_01934(accA1_2)
AMIN: AUMI_11100
AUW: AURUGA1_01300(accC)
ARR: ARUE_c00510(bccA1) ARUE_c13260(bccA2) ARUE_c14420(accA)
ARX: ARZXY2_2451(bccA) ARZXY2_2627(bccA) ARZXY2_3560(bccA) ARZXY2_3845(bccA)
AAU: AAur_0054 AAur_1410(accA) AAur_1529(accA)
KRH: KRH_16980(accA) KRH_21140(accA) KRH_22760(accA)
JDE: Jden_0845
IDO: I598_1309(cfiB) I598_1784(accA1_1)
CFL: Cfla_1034
SERJ: SGUI_3116
DCO: SAMEA4475696_0772(cfiB_1)
PAC: PPA1719
PAW: PAZ_c17910(bccA)
PACC: PAC1_08845
PACH: PAGK_1648
CACN: RN83_08920
CGRN: 4412665_01721(accC)
PFR: PFREUD_07100(accA)
PFRE: RM25_0676
PAUS: NCTC13651_01705(accC)
PPC: HMPREF9154_0932(pycA)
ACIJ: JS278_01071(cfiB)
NDK: I601_0193(accC)
KFL: Kfla_1405
MGG: MPLG2_2219(bccA)
NAL: B005_0220(accA1) B005_1111
STRR: EKD16_03145(cfiB) EKD16_09535(accA1)
FAL: FRAAL1210(accC) FRAAL2344(accC) FRAAL3159(accC)
MMAR: MODMU_1451 MODMU_4770(bccA)
SACC: EYD13_03280(accA1) EYD13_16920(accA3)
AOI: AORI_0928(bccA) AORI_6738(bccA)
AJA: AJAP_05430(accA1) AJAP_34925(bccA)
AMYY: YIM_05855(accA1) YIM_42995(accC2)
AHG: AHOG_24040(accA3) AHOG_24850(accC2)
SAQ: Sare_0792
MIL: ML5_1073
ASE: ACPL_7727(accA)
ACTN: L083_7486
AFS: AFR_39385
ACTS: ACWT_7596
SNA: Snas_0782
TPYO: X956_03675
TBW: NCTC13354_01641(accC)
AHW: NCTC11636_00338(accC)
AIR: NCTC12972_00817(accA1)
ASLA: NCTC11923_01938(accC)
AVC: NCTC10951_00772(accA1)
BLO: BL1535(jadJ)
BLJ: BLD_1631
BLN: Blon_2286
BLON: BLIJ_2359
BLF: BLIF_1805
BLL: BLJ_1809
BLM: BLLJ_1732
BLG: BIL_04900
BAD: BAD_0254
BADL: BADO_0262
BLA: BLA_0132 BLA_0300(jadJ)
BDE: BDP_0107 BDP_0360(accC)
BBP: BBPR_1640(accC)
BBI: BBIF_1581(accC)
BBF: BBB_1616(bccA)
BBRU: Bbr_1721(accC)
BBRE: B12L_1651
BBRV: B689b_1749
BBRJ: B7017_1915
BBRC: B7019_1887
BBRN: B2258_1741
BBRS: BS27_1714(accC)
BBRD: BBBR_1722
BAST: BAST_1441
BKS: BBKW_0272
BCAT: BBCT_0237
BPSP: AH67_01690
BANG: BBAG_0157
BPSC: BBPC_0266
BSCA: BBSC_0377
GVG: HMPREF0421_21230(bccA)
SIJ: SCIP_0274
PDO: PSDT_1230
RXY: Rxyl_2464
AFO: Afer_0730
AYM: YM304_28760(accA)
RCA: Rcas_4290
CAU: Caur_1378
CAG: Cagg_2537
HAU: Haur_4207
STI: Sthe_2003
TTR: Tter_1619
HAL: VNG_1532G(acc)
HSL: OE_3177F(pccA2)
HHB: Hhub_2879(pccA)
HSU: HLASF_1696(accC)
HSF: HLASA_1683(accC)
HMA: rrnAC0002(accC2) rrnB0263(accC1)
HHI: HAH_0766(accC2) HAH_4373(accC1)
NPH: NP_4252A(pccA1) NP_4368A(pccA2)
NMO: Nmlp_3309(pccA)
HMU: Hmuk_2575
HALL: LC1Hm_1915(pccA)
HWA: HQ_2906A(pccA)
HWC: Hqrw_3306(pccA)
HVO: HVO_2486(bccA)
HME: HFX_2490(accA2)
HLA: Hlac_2540
HDF: AArcSl_1438(bccA)
HTU: Htur_1729
NMG: Nmag_2123(pccA1) Nmag_3094(pccA2) Nmag_4033(pccA3)
SALI: L593_09100
 » show all
Reference
  Authors
Hou J, Xiang H, Han J
  Title
Propionyl coenzyme A (propionyl-CoA) carboxylase in Haloferax mediterranei: Indispensability for propionyl-CoA assimilation and impacts on global metabolism.
  Journal
Appl Environ Microbiol 81:794-804 (2015)
DOI:10.1128/AEM.03167-14
  Sequence
[hme:HFX_2490]
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