KEGG   ORTHOLOGY: K11304
Entry
K11304                      KO                                     

Name
TIP60, KAT5, ESA1
Definition
histone acetyltransferase HTATIP [EC:2.3.1.48]
Pathway
ko05017  Spinocerebellar ataxia
ko05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP
   03036 Chromosome and associated proteins
    K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   Cys2HisCys zinc factors
    K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP
   HAT complexes
    TIP60 complex
     K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP
    NuA4 complex
     K11304  TIP60, KAT5, ESA1; histone acetyltransferase HTATIP
Other DBs
GO: 0004402
Genes
HSA: 10524(KAT5)
PTR: 451329(KAT5)
PPS: 100986738(KAT5)
GGO: 101151018(KAT5)
PON: 100174410(KAT5)
NLE: 100589110(KAT5)
MCC: 715880(KAT5)
MCF: 102125755(KAT5)
CSAB: 103226976(KAT5)
RRO: 104664813(KAT5)
RBB: 108518700(KAT5)
CJC: 100386097(KAT5)
SBQ: 101041150(KAT5)
MMU: 81601(Kat5)
MCAL: 110285313(Kat5)
MPAH: 110312918(Kat5)
RNO: 192218(Kat5)
MUN: 110549323(Kat5)
CGE: 100761603(Kat5)
NGI: 103724996(Kat5)
HGL: 101715110(Kat5)
CCAN: 109687139(Kat5)
OCU: 100340634(KAT5)
TUP: 102478867(KAT5)
CFA: 483728(KAT5)
VVP: 112924252(KAT5)
AML: 100465899(KAT5)
UMR: 103679585(KAT5)
UAH: 113244098(KAT5)
ORO: 101380153(KAT5)
ELK: 111149712
FCA: 101099586(KAT5)
PTG: 102972308(KAT5)
PPAD: 109246750(KAT5)
AJU: 106971218(KAT5)
BTA: 505619(KAT5)
BOM: 102278226(KAT5)
BIU: 109554534(KAT5)
BBUB: 102396976(KAT5)
CHX: 100861366(KAT5)
OAS: 101109495(KAT5)
SSC: 100511913(KAT5)
CFR: 102514207(KAT5)
CDK: 105102592(KAT5)
BACU: 103020179(KAT5)
LVE: 103086473(KAT5)
OOR: 101271074(KAT5)
DLE: 111183743(KAT5)
PCAD: 102974775(KAT5)
ECB: 100051541(KAT5)
EPZ: 103560065(KAT5)
EAI: 106833565(KAT5)
MYB: 102255979(KAT5)
MYD: 102760765(KAT5)
MNA: 107533622(KAT5)
HAI: 109384147(KAT5)
DRO: 112317174(KAT5)
PALE: 102887245(KAT5)
RAY: 107497512(KAT5)
MJV: 108397003(KAT5)
LAV: 100660228(KAT5)
TMU: 101359652
MDO: 100016743(KAT5)
SHR: 100932216(KAT5)
PCW: 110195564(KAT5)
OAA: 114810247(KAT5)
GGA: 395413(KAT5)
ACYG: 106049800
TGU: 115492070(KAT5)
LSR: 110478846(KAT5)
PHI: 102103280(KAT5)
ASN: 102377696(KAT5)
AMJ: 102572350(KAT5)
PSS: 102456484(KAT5)
CMY: 102946842(KAT5)
CPIC: 101932006(KAT5)
ACS: 100565870(kat5)
PVT: 110069794(KAT5) 110069898
PBI: 103048961(KAT5)
PMUR: 107297119(KAT5)
TSR: 106543362(KAT5)
PMUA: 114586301(KAT5)
GJA: 107115218(KAT5)
XLA: 108713942(kat5.L)
XTR: 779727(kat5)
NPR: 108784122(KAT5)
DRE: 436638(kat5a) 503731(kat5b)
IPU: 108259920(kat5)
PHYP: 113531142(kat5)
AMEX: 103039324(kat5)
EEE: 113582118(kat5)
TRU: 101069305(kat5)
LCO: 104934511(kat5)
NCC: 104950150(kat5)
MZE: 101476849(kat5)
ONL: 100696624(kat5)
OLA: 101161500(kat5)
XMA: 102225592(kat5)
XCO: 114153463(kat5)
PRET: 103475818(kat5)
CVG: 107089857(kat5)
NFU: 107386462(kat5)
KMR: 108245243(kat5)
ALIM: 106516337(kat5)
AOCE: 111575209(kat5)
CSEM: 103395306(kat5)
POV: 109628391(kat5)
LCF: 108893587(kat5)
SDU: 111234604(kat5)
SLAL: 111654010(kat5)
HCQ: 109517874(kat5)
BPEC: 110158414(kat5)
MALB: 109959567(kat5)
ELS: 105010917(kat5)
SFM: 108925468(kat5)
PKI: 111859842(kat5)
LCM: 102364037(KAT5)
CMK: 103191031
CIN: 100177949
SPU: 580902
APLC: 110987565
SKO: 100374213
DME: Dmel_CG6121(Tip60)
DER: 6550973
DSE: 6612535
DSI: Dsimw501_GD16311(Dsim_EG:EG0007.7)
DYA: Dyak_GE16871(Dyak_EG:EG0007.7)
DAN: 6504173
DSR: 110183054
DVI: 6633774
MDE: 101893518
LCQ: 111684236
AAG: 5579231
AALB: 109418279
AME: 413101
BIM: 100740352
BTER: 100652130
CCAL: 108624397
OBB: 114878521
SOC: 105199634
MPHA: 105829351
AEC: 105151620
ACEP: 105617467
PBAR: 105430441
VEM: 105570206
HST: 105182752
DQU: 106745909
CFO: 105255901
LHU: 105676244
PGC: 109859928
OBO: 105286526
NVI: 100122899
CSOL: 105363226
MDL: 103576348
TCA: 664310
DPA: 109534434
ATD: 109599926
NVL: 108569214
BMOR: 101740289
BMAN: 114240937
PMAC: 106710978
PRAP: 110995904
HAW: 110384579
TNL: 113496098
PXY: 105380072
API: 100167126
AGS: 114123914
RMD: 113556748
BTAB: 109032912
CLEC: 106661094
ZNE: 110826618
FCD: 110853825
PVM: 113803928
TUT: 107367519
DPTE: 113791628
PTEP: 107440453
CEL: CELE_VC5.4(mys-1)
CBR: CBG19077(Cbr-mys-1)
BMY: Bm1_24465
TSP: Tsp_05023
PCAN: 112570196
CRG: 105342395
MYI: 110466367
OBI: 106879052
LAK: 106168972
EGL: EGR_03479
EPA: 110233947
ADF: 107354886
AMIL: 114947506
PDAM: 113670564
SPIS: 111327983
DGT: 114522128
HMG: 100213192
AQU: 100633667
SCE: YOR244W(ESA1)
ERC: Ecym_2400
KMX: KLMA_20206(ESA1)
NCS: NCAS_0B01620(NCAS0B01620)
NDI: NDAI_0E01170(NDAI0E01170)
TPF: TPHA_0D01230(TPHA0D01230)
TBL: TBLA_0C01850(TBLA0C01850)
TDL: TDEL_0A06190(TDEL0A06190)
KAF: KAFR_0A03850(KAFR0A03850)
CAL: CAALFM_C300490WA(ESA1)
SLB: AWJ20_3913(ESA1)
NCR: NCU05218(hat-4)
NTE: NEUTE1DRAFT80548(NEUTE1DRAFT_80548)
MGR: MGG_04133
SSCK: SPSK_07426
NHE: NECHADRAFT_44019(HAM2102)
MAW: MAC_08180
MAJ: MAA_02727
CMT: CCM_00422
BFU: BCIN_12g06640(Bcesa1)
MBE: MBM_03322
ANG: ANI_1_1914024(An02g13870)
ABE: ARB_03883
TVE: TRV_06628
PTE: PTT_10387
ZTR: MYCGRDRAFT_101232(HAM2402)
SPO: SPAC637.12c(mst1)
CNE: CNB03160
CNB: CNBB2530
TASA: A1Q1_00737
LBC: LACBIDRAFT_246659(HAM16203)
ABP: AGABI1DRAFT55679(AGABI1DRAFT_55679)
ABV: AGABI2DRAFT185135(AGABI2DRAFT_185135)
MGL: MGL_1551
MRT: MRET_3805
DFA: DFA_06488
 » show all
Reference
  Authors
Sun Y, Jiang X, Chen S, Fernandes N, Price BD
  Title
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM.
  Journal
Proc Natl Acad Sci U S A 102:13182-7 (2005)
DOI:10.1073/pnas.0504211102
  Sequence
[hsa:10524]
Reference
PMID:8607265
  Authors
Kamine J, Elangovan B, Subramanian T, Coleman D, Chinnadurai G
  Title
Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator.
  Journal
Virology 216:357-66 (1996)
DOI:10.1006/viro.1996.0071
  Sequence
[hsa:10524]
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