KEGG   ORTHOLOGY: K11541
Entry
K11541                      KO                                     
Symbol
URA2
Name
carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
Pathway
map00240  Pyrimidine metabolism
map00250  Alanine, aspartate and glutamate metabolism
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Module
M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Reaction
R00256  L-glutamine amidohydrolase
R00575  HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)
R01395  ATP:carbamate phosphotransferase
R01397  carbamoyl-phosphate:L-aspartate carbamoyltransferase
R10948  ATP:HCO3- phosphotransferase
R10949  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     K11541  URA2; carbamoyl-phosphate synthase / aspartate carbamoyltransferase
Other DBs
GO: 0004088 0004070
Genes
SCE: YJL130C(URA2)
SEUB: DI49_2892
SPAO: SPAR_J00800
AGO: AGOS_ACR263C
ERC: Ecym_5206
KLA: KLLA0_E15357g
KMX: KLMA_60037(URA2)
LTH: KLTH0F05874g
VPO: Kpol_448p15
ZRO: ZYRO0D03300g
CGR: CAGL0L05676g
NCS: NCAS_0A09770(NCAS0A09770)
NDI: NDAI_0G06170(NDAI0G06170)
TPF: TPHA_0B03110(TPHA0B03110)
TBL: TBLA_0B07830(TBLA0B07830)
TGB: HG536_0F01080
TDL: TDEL_0H01050(TDEL0H01050)
KAF: KAFR_0F02010(KAFR0F02010)
KNG: KNAG_0C02690(KNAG0C02690)
ZMK: HG535_0C00940
PPA: PAS_chr2-2_0142
DHA: DEHA2A10384g
PIC: PICST_90563(URA2)
PGU: PGUG_01980
SPAA: SPAPADRAFT_49095
LEL: PVL30_002943(URA2)
CAL: CAALFM_CR07050CA(URA2)
CTP: CTRG_03135
COT: CORT_0D03260
CDU: CD36_32590
CTEN: CANTEDRAFT_109941
YLI: YALI0E09493g
CLU: CLUG_04779
CLUS: A9F13_11g00132
CAUR: CJI96_0002752
SLB: AWJ20_2038(URA2)
PKZ: C5L36_0C03730
BNN: FOA43_002511(URA2)
BBRX: BRETT_000063(URA2)
OPA: HPODL_00057
SLUD: SCDLUD_002630
NCR: NCU08287(pyr-3)
NTE: NEUTE1DRAFT128592(NEUTE1DRAFT_128592)
SMP: SMAC_00930
PAN: PODANSg7147
PBEL: QC761_606090(URA2)
PPSD: QC762_606090(URA2)
PPSP: QC763_606090(URA2)
PPSA: QC764_606090(URA2)
TTT: THITE_2115457
MTM: MYCTH_2299023
CTHR: CTHT_0032600
MGR: MGG_01537
PPEI: PpBr36_01052
PGRI: PgNI_03967
TMN: UCRPA7_7878
SSCK: SPSK_00652
FGR: FGSG_09638
FPU: FPSE_05918
FPOA: FPOAC1_012011
FVN: FVRRES_13081
FVR: FVEG_04203
FOX: FOXG_06351
NHE: NECHADRAFT_103501
FFC: NCS54_00281200
FKR: NCS57_00277200
FMU: J7337_004201
TRE: TRIREDRAFT_55928
TRR: M419DRAFT_5640
MAW: MAC_06383
MAJ: MAA_06517
PCHM: VFPPC_09022
CMT: CCM_04128
AMUS: LMH87_006695
PLJ: VFPFJ_00849
PTKZ: JDV02_007809(URA2)
VAL: VDBG_00866
VDA: VDAG_00477
CFJ: CFIO01_12029
CLUP: CLUP02_17471
CHIG: CH63R_07786
SAPO: SAPIO_CDS7513
ELA: UCREL1_6069
PFY: PFICI_05144
SSL: SS1G_08553
BFU: BCIN_12g04860
MBE: MBM_04336
PSCO: LY89DRAFT_790580
GLZ: GLAREA_10907
ANI: ANIA_00565
AFM: AFUA_6G11310
ACT: ACLA_084980
NFI: NFIA_057010
AOR: AO090023000483
ANG: An08g07420
AFV: AFLA_006827
ALUC: AKAW2_30351S
ACHE: ACHE_60114A
APUU: APUU_11522S
PCS: N7525_006351
PDP: PDIP_39750
POU: POX_d04845
TMF: EYB26_008391
TRG: TRUGW13939_00157
CIM: CIMG_09796
CPW: CPC735_022860
URE: UREG_04713
PBL: PAAG_05242
PBN: PADG_05071
ABE: ARB_01717
TVE: TRV_03411
AJE: HCAG_08357
BGH: BDBG_01634
PNO: SNOG_08506
PTE: PTT_17704
BZE: COCCADRAFT_8075
BSC: COCSADRAFT_78202
BOR: COCMIDRAFT_728
AALT: CC77DRAFT_989762
ZTR: MYCGRDRAFT_110798
PFJ: MYCFIDRAFT_86968
CBET: CB0940_06934
BCOM: BAUCODRAFT_152247
NPA: UCRNP2_6662
TML: GSTUM_00005367001
SPO: SPAC22G7.06c(ura1)
SOM: SOMG_01656(ura1)
CNE: CNA06000
CNB: CNBA5810
CNG: CNAG_07373
CGI: CGB_A6470C
CDEU: CNBG_9118
TMS: TREMEDRAFT_72254
CCAC: CcaHIS019_0212810(URA2)
TVS: TRAVEDRAFT_155672
DSQ: DICSQDRAFT_87297
PCO: PHACADRAFT_103993
SHS: STEHIDRAFT_169813
HIR: HETIRDRAFT_53393
PSQ: PUNSTDRAFT_90646
ADL: AURDEDRAFT_107770
FME: FOMMEDRAFT_169884
GTR: GLOTRDRAFT_63880
RSX: RhiXN_07705
LBC: LACBIDRAFT_294748
CCI: CC1G_04764
ABP: AGABI1DRAFT122679(AGABI1DRAFT_122679)
ABV: AGABI2DRAFT188488(AGABI2DRAFT_188488)
PCUB: JR316_0012332
MRR: Moror_3989
MORE: E1B28_012198
SCM: SCHCO_02629622(SCHCODRAFT_02629622)
CPUT: CONPUDRAFT_109182
SLA: SERLADRAFT_362361
WSE: WALSEDRAFT_31765
WIC: J056_002512
UMA: UMAG_15005
PFP: PFL1_02607
SGRA: EX895_006517
MGL: MGL_1489
MRT: MRET_3870
MSYM: MSY001_2403
PGR: PGTG_15132
PTRC: PtA15_6A721
PSTR: Pst134EA_002821
MLR: MELLADRAFT_45459
BBIG: BBBOND_0311560
 » show all
Reference
PMID:2570735
  Authors
Souciet JL, Nagy M, Le Gouar M, Lacroute F, Potier S
  Title
Organization of the yeast URA2 gene: identification of a defective dihydroorotase-like domain in the multifunctional carbamoylphosphate synthetase-aspartate transcarbamylase complex.
  Journal
Gene 79:59-70 (1989)
DOI:10.1016/0378-1119(89)90092-9
  Sequence
[sce:YJL130C]
LinkDB

DBGET integrated database retrieval system