KEGG   ORTHOLOGY: K12159
Entry
K12159                      KO                                     

Name
ISG15
Definition
ubiquitin cross-reactive protein
Pathway
ko04622  RIG-I-like receptor signaling pathway
ko05165  Human papillomavirus infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
Disease
H00089  IFN-gamma/IL-12 axis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    K12159  ISG15; ubiquitin cross-reactive protein
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    K12159  ISG15; ubiquitin cross-reactive protein
   05169 Epstein-Barr virus infection
    K12159  ISG15; ubiquitin cross-reactive protein
   05165 Human papillomavirus infection
    K12159  ISG15; ubiquitin cross-reactive protein
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K12159  ISG15; ubiquitin cross-reactive protein
Ubiquitin system [BR:ko04121]
 Ubiquitins and ubiquitin-like proteins
  Ubiquitin-like proteins (UBLs)
   K12159  ISG15; ubiquitin cross-reactive protein
Genes
HSA: 9636(ISG15)
PTR: 100609237(ISG15)
PPS: 100989384(ISG15)
PON: 100461684(ISG15)
NLE: 115833016(ISG15)
MCC: 700141(ISG15)
MCF: 102119028(ISG15)
CSAB: 103225828(ISG15)
RRO: 104673206(ISG15)
RBB: 108516786(ISG15)
CJC: 100384985(ISG15)
SBQ: 101047532(ISG15)
MMU: 100038882(Isg15)
MCAL: 110292529(Isg15)
MPAH: 110323809(Isg15)
RNO: 298693(Isg15)
MUN: 110560368(Isg15)
CGE: 100772582(Isg15)
NGI: 103749728(Isg15)
HGL: 101725499(Isg15)
CCAN: 109685577(Isg15)
OCU: 100354504(ISG15)
TUP: 102496379(ISG15)
CFA: 100855667(ISG15)
VVP: 112926136(ISG15)
AML: 100469387(ISG15)
UMR: 103682059(ISG15)
UAH: 113270654(ISG15)
ORO: 101366118(ISG15)
ELK: 111154860
FCA: 100174787(ISG15)
PTG: 102971262(ISG15)
PPAD: 109273903(ISG15)
AJU: 106988777(ISG15)
BTA: 281871(ISG15)
BOM: 102276802(ISG15)
BIU: 109570760(ISG15)
BBUB: 102401758(ISG15)
CHX: 102169982(ISG15)
OAS: 443057(ISG15)
SSC: 100145895(ISG15)
CFR: 102506432(ISG15)
CDK: 105105589(ISG15)
BACU: 103014948(ISG15)
LVE: 103076606
OOR: 101275176(ISG15)
DLE: 111187178(ISG15)
PCAD: 102986939(ISG15)
ECB: 100066364(ISG15)
EPZ: 103558553(ISG15)
EAI: 106845250(ISG15)
MYB: 102260813(ISG15)
MYD: 102760772(ISG15)
HAI: 109391180(ISG15)
DRO: 112299549(ISG15)
PALE: 102878693(ISG15)
RAY: 107510656(ISG15)
MJV: 108405696(ISG15)
LAV: 100661639(ISG15)
TMU: 101343892
MDO: 100020081(ISG15)
PCW: 110201233(ISG15)
OAA: 114809060(ISG15)
CMY: 102937006
CPIC: 101946299(ISG15)
ACS: 103280520(isg15)
PBI: 103049269(ISG15)
PMUR: 107285475(ISG15)
TSR: 106552569(ISG15)
PMUA: 114586820(ISG15)
GJA: 107122107
 » show all
Reference
  Authors
Zhao C, Denison C, Huibregtse JM, Gygi S, Krug RM
  Title
Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.
  Journal
Proc Natl Acad Sci U S A 102:10200-5 (2005)
DOI:10.1073/pnas.0504754102
  Sequence
[hsa:9636]
Reference
PMID:3087979
  Authors
Blomstrom DC, Fahey D, Kutny R, Korant BD, Knight E Jr
  Title
Molecular characterization of the interferon-induced 15-kDa protein. Molecular cloning and nucleotide and amino acid sequence.
  Journal
J Biol Chem 261:8811-6 (1986)
  Sequence
[hsa:9636]
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