KEGG   ORTHOLOGY: K12250
Entry
K12250                      KO                                     

Name
E4.2.3.7
Definition
pentalenene synthase [EC:4.2.3.7]
Pathway
ko00909  Sesquiterpenoid and triterpenoid biosynthesis
ko00999  Biosynthesis of various secondary metabolites - part 1
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00819  Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K12250  E4.2.3.7; pentalenene synthase
  09110 Biosynthesis of other secondary metabolites
   00999 Biosynthesis of various secondary metabolites - part 1
    K12250  E4.2.3.7; pentalenene synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.7  pentalenene synthase
     K12250  E4.2.3.7; pentalenene synthase
Other DBs
RN: R02305
GO: 0050467
Genes
MFB: MFUL124B02_01465 MFUL124B02_01475 MFUL124B02_01480
SMA: SAVERM_2998(ptlA)
SBH: SBI_09679
SCI: B446_29695
SCW: TU94_27405
SLE: sle_13160(sle_13160)
SSIA: A7J05_09240
Reference
PMID:8180213
  Authors
Cane DE, Sohng JK, Lamberson CR, Rudnicki SM, Wu Z, Lloyd MD, Oliver JS, Hubbard BR
  Title
Pentalenene synthase. Purification, molecular cloning, sequencing, and high-level expression in Escherichia coli of a terpenoid cyclase from Streptomyces UC5319.
  Journal
Biochemistry 33:5846-57 (1994)
DOI:10.1021/bi00185a024
  Sequence
[sbh:SBI_09679]
Reference
  Authors
Tetzlaff CN, You Z, Cane DE, Takamatsu S, Omura S, Ikeda H
  Title
A gene cluster for biosynthesis of the sesquiterpenoid antibiotic pentalenolactone in Streptomyces avermitilis.
  Journal
Biochemistry 45:6179-86 (2006)
DOI:10.1021/bi060419n
LinkDB

DBGET integrated database retrieval system