KEGG   ORTHOLOGY: K12570
Entry
K12570                      KO                                     

Name
aphD, strA
Definition
streptomycin 6-kinase [EC:2.7.1.72]
Pathway
ko00521  Streptomycin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    K12570  aphD, strA; streptomycin 6-kinase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K12570  aphD, strA; streptomycin 6-kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.72  streptomycin 6-kinase
     K12570  aphD, strA; streptomycin 6-kinase
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  Aminoglycoside resistance genes
   O-Phosphotransferases
    K12570  aphD, strA; streptomycin 6-kinase
Other DBs
RN: R02225
GO: 0050300
Genes
SGR: SGR_5932(aphD)
SFA: Sfla_6555
SGU: SGLAU_01165(sph)
SLD: T261_7610
NAL: B005_4930
AG: AAX82592(aph(6)-Ia) CAA29136(aph(6)-Ib)
Reference
PMID:8385262
  Authors
Shaw KJ, Rather PN, Hare RS, Miller GH
  Title
Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.
  Journal
Microbiol Rev 57:138-63 (1993)
Reference
PMID:2995326
  Authors
Ohnuki T, Imanaka T, Aiba S
  Title
Self-cloning in Streptomyces griseus of an str gene cluster for streptomycin biosynthesis and streptomycin resistance.
  Journal
J Bacteriol 164:85-94 (1985)
DOI:10.1128/JB.164.1.85-94.1985
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