KEGG   ORTHOLOGY: K12675
Entry
K12675                      KO                                     

Name
cs
Definition
clavaminate synthase [EC:1.14.11.21]
Pathway
ko00331  Clavulanic acid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00674  Clavaminate biosynthesis, arginine + glyceraldehyde-3P => clavaminate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00331 Clavulanic acid biosynthesis
    K12675  cs; clavaminate synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.21  clavaminate synthase
     K12675  cs; clavaminate synthase
Other DBs
RN: R05466 R05468 R05469
GO: 0033758
Genes
SFA: Sfla_0558
STRP: F750_6321
SCLF: BB341_13950
SFK: KY5_8015c
KAB: B7C62_18900
KAU: B6264_26740
SVI: Svir_33410
AG: AAA26722(cs1)
Reference
PMID:7601835 (Cyanobacteria_CYB)
  Authors
Wu TK, Busby RW, Houston TA, McIlwaine DB, Egan LA, Townsend CA
  Title
Identification, cloning, sequencing, and overexpression of the gene encoding proclavaminate amidino hydrolase and characterization of protein function in clavulanic acid biosynthesis.
  Journal
J Bacteriol 177:3714-20 (1995)
DOI:10.1128/JB.177.13.3714-3720.1995
Reference
  Authors
Zhang Z, Ren J, Stammers DK, Baldwin JE, Harlos K, Schofield CJ
  Title
Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
  Journal
Nat Struct Biol 7:127-33 (2000)
DOI:10.1038/72398
  Sequence
LinkDB

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