KEGG   ORTHOLOGY: K12719
Entry
K12719            Tight     KO                                     

Name
cloN4, couN4
Definition
L-proline---[L-prolyl-carrier protein] ligase [EC:6.2.1.53]
Pathway
ko00401  Novobiocin biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00401 Novobiocin biosynthesis
    K12719  cloN4, couN4; L-proline---[L-prolyl-carrier protein] ligase
Enzymes [BR:ko01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.53  L-proline---[L-prolyl-carrier protein] ligase
     K12719  cloN4, couN4; L-proline---[L-prolyl-carrier protein] ligase
Other DBs
RN: R06746 R12056 R12057
COG: COG1020 COG0318
Genes
AG: AAG29789(couN4) AAN65233(cloN4)
Reference
  Authors
Pojer F, Li SM, Heide L.
  Title
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.
  Journal
Microbiology 148:3901-11 (2002)
DOI:10.1099/00221287-148-12-3901
  Sequence
Reference
  Authors
Wang ZX, Li SM, Heide L
  Title
Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489.
  Journal
Antimicrob Agents Chemother 44:3040-8 (2000)
DOI:10.1128/AAC.44.11.3040-3048.2000
  Sequence
LinkDB

KEGG   ORTHOLOGY: K12720
Entry
K12720            Tight     KO                                     

Name
cloN5, couN5
Definition
peptidyl carrier protein
Pathway
ko00401  Novobiocin biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00401 Novobiocin biosynthesis
    K12720  cloN5, couN5; peptidyl carrier protein
Other DBs
RN: R06746 R12056 R12057
COG: COG0236
Genes
AG: AAG29790(couN5) AAN65234(cloN5)
Reference
  Authors
Pojer F, Li SM, Heide L.
  Title
Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics.
  Journal
Microbiology 148:3901-11 (2002)
DOI:10.1099/00221287-148-12-3901
  Sequence
Reference
  Authors
Wang ZX, Li SM, Heide L
  Title
Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489.
  Journal
Antimicrob Agents Chemother 44:3040-8 (2000)
DOI:10.1128/AAC.44.11.3040-3048.2000
  Sequence
Reference
  Authors
Garneau S, Dorrestein PC, Kelleher NL, Walsh CT
  Title
Characterization of the formation of the pyrrole moiety during clorobiocin and coumermycin A1 biosynthesis.
  Journal
Biochemistry 44:2770-80 (2005)
DOI:10.1021/bi0476329
LinkDB

DBGET integrated database retrieval system