KEGG   ORTHOLOGY: K12791
Entry
K12791                      KO                                     

Name
ARHGEF2, GEF-H1
Definition
Rho guanine nucleotide exchange factor 2
Pathway
ko04530  Tight junction
ko05130  Pathogenic Escherichia coli infection
ko05131  Shigellosis
ko05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K12791  ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K12791  ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K12791  ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
   05131 Shigellosis
    K12791  ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12791  ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
Membrane trafficking [BR:ko04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    K12791  ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
Other DBs
GO: 0005089 0030676
Genes
HSA: 9181(ARHGEF2)
PTR: 457378(ARHGEF2)
PPS: 100985016(ARHGEF2)
GGO: 101137778(ARHGEF2)
PON: 100434709(ARHGEF2)
NLE: 100601565(ARHGEF2)
MCC: 719369(ARHGEF2)
MCF: 102131561(ARHGEF2)
CSAB: 103223865(ARHGEF2)
RRO: 104666104(ARHGEF2)
RBB: 108515504(ARHGEF2)
CJC: 100410054(ARHGEF2)
SBQ: 101050808(ARHGEF2)
MMU: 16800(Arhgef2)
MCAL: 110290909(Arhgef2)
MPAH: 110319838(Arhgef2)
RNO: 310635(Arhgef2)
MUN: 110548972(Arhgef2)
CGE: 100758849(Arhgef2)
NGI: 103750677(Arhgef2)
HGL: 101698496(Arhgef2)
CCAN: 109676179 109697617(Arhgef2)
OCU: 100346634(ARHGEF2)
TUP: 102480580(ARHGEF2)
CFA: 403498(ARHGEF2)
VVP: 112918934(ARHGEF2)
AML: 100476171(ARHGEF2)
UMR: 103668692(ARHGEF2)
UAH: 113245255(ARHGEF2)
ORO: 101385607(ARHGEF2)
ELK: 111138883
FCA: 101087196(ARHGEF2)
PTG: 102969284(ARHGEF2)
PPAD: 109256294(ARHGEF2)
AJU: 106981513
BTA: 505940(ARHGEF2)
BOM: 102278165(ARHGEF2)
BIU: 109553423(ARHGEF2)
BBUB: 102394642(ARHGEF2)
CHX: 102181739(ARHGEF2)
OAS: 101121729(ARHGEF2)
SSC: 100145887(ARHGEF2)
CFR: 102514672(ARHGEF2)
CDK: 105105664(ARHGEF2)
BACU: 103009184(ARHGEF2)
LVE: 103083503(ARHGEF2)
OOR: 101285147
DLE: 111167163(ARHGEF2)
PCAD: 102979146(ARHGEF2)
ECB: 100057582(ARHGEF2)
EPZ: 103548817(ARHGEF2)
EAI: 106828479(ARHGEF2)
MYB: 102259302(ARHGEF2)
MYD: 102763460(ARHGEF2)
MNA: 107543816(ARHGEF2)
HAI: 109393427(ARHGEF2)
DRO: 112317066(ARHGEF2)
PALE: 102896899(ARHGEF2)
RAY: 107521493(ARHGEF2)
MJV: 108405067(ARHGEF2)
LAV: 100661367(ARHGEF2)
TMU: 101346957
MDO: 100617588(ARHGEF2)
SHR: 100933486(ARHGEF2)
PCW: 110211935(ARHGEF2)
OAA: 114807981(ARHGEF2)
TGU: 115498401(ARHGEF2)
LSR: 110476857
SCAN: 103824796(ARHGEF2)
GFR: 102035205(ARHGEF2)
PHI: 102104974(ARHGEF2)
PMAJ: 107214694(ARHGEF2)
ETL: 114072420
FPG: 101919506(ARHGEF2)
FCH: 114016779
NNI: 104014463(ANKRD35)
ASN: 102388381(ARHGEF2)
AMJ: 102558337(ARHGEF2)
PSS: 102461987
CMY: 102935687(ARHGEF2)
CPIC: 101947435(ARHGEF2)
ACS: 100560612(arhgef2) 103282867
PVT: 110083746(ARHGEF2)
PBI: 103067930
TSR: 106546033(ARHGEF2)
PMUA: 114586056(ARHGEF2)
GJA: 107110123(ARHGEF2)
XLA: 108699605(arhgef2.L) 398353(arhgef2.S)
XTR: 407848(arhgef2)
NPR: 108800773(ARHGEF2)
DRE: 368266(arhgef1a) 561276(arhgef2)
IPU: 108272707(arhgef2) 108280391
AMEX: 103025304(arhgef2)
EEE: 113584952 113589117(arhgef2)
LCO: 104933078(arhgef2) 104937303
OLA: 101169675(arhgef2)
XMA: 102217389(arhgef2)
XCO: 114140860(arhgef2)
PRET: 103477448(arhgef2)
CVG: 107095261
NFU: 107379241(arhgef2)
KMR: 108248729(arhgef2)
CSEM: 103388044 103394490(arhgef2)
POV: 109643149 109644354(arhgef2)
LCF: 108884698 108896392(arhgef2)
HCQ: 109512131 109514556(arhgef2)
BPEC: 110153610 110167926(arhgef2)
MALB: 109970920 109974562(arhgef2)
ELS: 105012729(arhgef2) 105019166
SFM: 108925568(arhgef2)
LCM: 102363693(ARHGEF2)
 » show all
Reference
  Authors
Krendel M, Zenke FT, Bokoch GM
  Title
Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton.
  Journal
Nat Cell Biol 4:294-301 (2002)
DOI:10.1038/ncb773
  Sequence
[hsa:9181]
Reference
PMID:9857026
  Authors
Ren Y, Li R, Zheng Y, Busch H
  Title
Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases.
  Journal
J Biol Chem 273:34954-60 (1998)
DOI:10.1074/jbc.273.52.34954
  Sequence
[hsa:9181]
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