KEGG   ORTHOLOGY: K12911
Entry
K12911            Tight     KO                                     

Name
phsA
Definition
peptide synthetase PhsA
Pathway
ko00440  Phosphonate and phosphinate metabolism
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K12911  phsA; peptide synthetase PhsA
Other DBs
RN: R08872
Genes
AG: CAA46313(phsA)
Reference
  Authors
Lee JH, Evans BS, Li G, Kelleher NL, van der Donk WA
  Title
In vitro characterization of a heterologously expressed nonribosomal Peptide synthetase involved in phosphinothricin tripeptide biosynthesis.
  Journal
Biochemistry 48:5054-6 (2009)
DOI:10.1021/bi900164d
LinkDB

KEGG   REACTION: R08872
Entry
R08872                      Reaction                               

Name
N-acetyldemethylphosphinothricin:L-alanine:L-alanine ligase (AMP-forming)
Definition
N-Acetyldemethylphosphinothricin + 2 L-Alanine + 3 ATP + H2O <=> N-Acetyldemethylphosphinothricin tripeptide + 3 AMP + 3 Diphosphate
Equation
C17949 + 2 C00041 + 3 C00002 + C00001 <=> C17950 + 3 C00020 + 3 C00013
Comment
nonribosomal peptide synthetase
Reaction class
RC00064  C00041_C17950
RC00141  C17949_C17950
RC01227  C00041_C17950
Pathway
rn00440  Phosphonate and phosphinate metabolism
rn01110  Biosynthesis of secondary metabolites
Orthology
K12911  peptide synthetase PhsA
K12912  peptide synthetase PhsB
K12913  peptide synthetase PhsC
LinkDB

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