KEGG   ORTHOLOGY: K13060
Entry
K13060                      KO                                     

Name
lasI
Definition
acyl homoserine lactone synthase [EC:2.3.1.184]
Pathway
ko00270  Cysteine and methionine metabolism
ko01100  Metabolic pathways
ko02024  Quorum sensing
ko02025  Biofilm formation - Pseudomonas aeruginosa
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    K13060  lasI; acyl homoserine lactone synthase
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K13060  lasI; acyl homoserine lactone synthase
   02025 Biofilm formation - Pseudomonas aeruginosa
    K13060  lasI; acyl homoserine lactone synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.184  acyl-homoserine-lactone synthase
     K13060  lasI; acyl homoserine lactone synthase
Other DBs
RN: R08940
COG: COG3916
GO: 0061579
Genes
SOF: NCTC11214_01456(lasI)
EAME: GXP68_13300
LMB: C9I47_0679
LYJ: FKV23_13885
XBA: C7S18_10815
PAE: PA1432(lasI)
PAEV: N297_1473(lasI)
PAEI: N296_1473(lasI)
PAU: PA14_45940(lasI)
PAP: PSPA7_3897(lasI)
PAG: PLES_39821(lasI)
PAF: PAM18_3699(lasI)
PNC: NCGM2_2314(lasI)
PAEB: NCGM1900_5154(lasI)
PAEM: U769_18600
PAEL: T223_20340
PAEU: BN889_01520(lasI)
PAEG: AI22_14715
PAEC: M802_1470(lasI)
PAEO: M801_1472(lasI)
PSES: PSCI_0294(ppuI)
SPSW: Sps_00211
PAT: Patl_0361
SDE: Sde_3498
BMK: DM80_4757(lasI)
BDL: AK34_3747(lasI)
BXE: Bxe_B0608
BXB: DR64_5938(lasI)
BPH: Bphy_4437
BFN: OI25_6299(lasI)
GCA: Galf_1450
NIM: W01_04680(lasI)
PGD: Gal_02723
SECH: B18_18930
 » show all
Reference
PMID:8790360
  Authors
Schaefer AL, Val DL, Hanzelka BL, Cronan JE Jr, Greenberg EP
  Title
Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified Vibrio fischeri LuxI protein.
  Journal
Proc Natl Acad Sci U S A 93:9505-9 (1996)
DOI:10.1073/pnas.93.18.9505
Reference
  Authors
Gould TA, Schweizer HP, Churchill ME
  Title
Structure of the Pseudomonas aeruginosa acyl-homoserinelactone synthase LasI.
  Journal
Mol Microbiol 53:1135-46 (2004)
DOI:10.1111/j.1365-2958.2004.04211.x
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