KEGG   ORTHOLOGY: K13302
Entry
K13302                      KO                                     

Name
SGK1
Definition
serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
Pathway
ko04068  FoxO signaling pathway
ko04150  mTOR signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04960  Aldosterone-regulated sodium reabsorption
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K13302  SGK1; serum/glucocorticoid-regulated kinase 1
   04151 PI3K-Akt signaling pathway
    K13302  SGK1; serum/glucocorticoid-regulated kinase 1
   04150 mTOR signaling pathway
    K13302  SGK1; serum/glucocorticoid-regulated kinase 1
 09150 Organismal Systems
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K13302  SGK1; serum/glucocorticoid-regulated kinase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K13302  SGK1; serum/glucocorticoid-regulated kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K13302  SGK1; serum/glucocorticoid-regulated kinase 1
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  SGK family [OT]
   K13302  SGK1; serum/glucocorticoid-regulated kinase 1
Genes
HSA: 6446(SGK1)
PTR: 463011(SGK1)
PPS: 100984960(SGK1)
GGO: 101132422(SGK1)
PON: 100447685(SGK1)
NLE: 100586194(SGK1)
MCC: 713082(SGK1)
MCF: 101866184(SGK1)
CSAB: 103240340(SGK1)
RRO: 104678238
RBB: 108531834(SGK1)
CJC: 100389266(SGK1)
SBQ: 101046433(SGK1)
MMU: 20393(Sgk1)
MCAL: 110302862(Sgk1)
MPAH: 110338537(Sgk1)
RNO: 29517(Sgk1)
MUN: 110550419(Sgk1)
CGE: 100771433(Sgk1)
NGI: 103724913(Sgk1) 103733926
HGL: 101708117(Sgk1)
CCAN: 109697937(Sgk1)
OCU: 100008723(SGK1)
TUP: 102499967(SGK1)
CFA: 403647(SGK1)
VVP: 112919455(SGK1)
AML: 100468926(SGK1)
UMR: 103663385(SGK1)
UAH: 113259468(SGK1)
ORO: 101378055(SGK1)
ELK: 111147659
FCA: 101098954(SGK1)
PTG: 102966723(SGK1)
PPAD: 109249901(SGK1)
AJU: 106976864(SGK1)
BTA: 515854(SGK1)
BOM: 102272039(SGK1)
BIU: 109563967
BBUB: 102405402(SGK1)
CHX: 102176607(SGK1)
OAS: 101107709(SGK1)
SSC: 100625739(SGK1)
CFR: 102516719(SGK1)
CDK: 105096363(SGK1)
BACU: 103016100(SGK1)
LVE: 103071928(SGK1)
OOR: 101280111 101281043(SGK1)
ECB: 100073151(SGK1)
EPZ: 103556350
EAI: 106837176(SGK1)
MYB: 102250674(SGK1)
MYD: 102766031(SGK1)
MNA: 107530994(SGK1)
HAI: 109371924(SGK1)
DRO: 112297072(SGK1)
PALE: 102891704
RAY: 107516175(SGK1)
MJV: 108394031(SGK1)
LAV: 100666881
TMU: 101349244
MDO: 100025435(SGK1)
SHR: 100935143(SGK1)
PCW: 110208905(SGK1)
OAA: 100073891(SGK1)
GGA: 395133(SGK1)
MGP: 100541500(SGK1)
CJO: 107311699(SGK1)
NMEL: 110390596
APLA: 101801765
ACYG: 106032508(SGK1)
TGU: 100219883(SGK1)
LSR: 110476052(SGK1)
SCAN: 103820550(SGK1)
GFR: 102037330(SGK1)
FAB: 101810101(SGK1)
PHI: 102101880(SGK1)
PMAJ: 107202355
CCAE: 111927653(SGK1)
CCW: 104690470(SGK1)
ETL: 114065221(SGK1)
FPG: 101924246(SGK1)
FCH: 102052186
CLV: 102094792(SGK1)
EGZ: 104131203(SGK1)
NNI: 104008826(SGK1)
ACUN: 113478259(SGK1)
PADL: 103912698(SGK1)
AAM: 106498005(SGK1)
ASN: 102371183(SGK1)
AMJ: 102576261(SGK1)
PSS: 102450219(SGK1)
CMY: 102932644(SGK1)
CPIC: 101936659(SGK1)
ACS: 100565714(sgk1)
PVT: 110071906(SGK1)
PBI: 103054879
PMUR: 107289907(SGK1)
TSR: 106555854(SGK1)
PMUA: 114594162(SGK1)
GJA: 107111430(SGK1)
XLA: 399130(sgk1.L) 444618(sgk1.S)
XTR: 594981(sgk1)
NPR: 108794122
DRE: 324140(sgk1) 559050(sgk2b) 768159(si:ch211-195b13.1)
NCC: 104955017 104965738(sgk1)
CMK: 103179483 103185144(s-sgk1)
SPU: 576586
PVM: 113825060
TUT: 107366196
CEL: CELE_W10G6.2(sgk-1)
CBR: CBG16386(Cbr-sgk-1)
ADF: 107329566
SPAR: SPRG_09607
 » show all
Reference
  Authors
Verrey F, Loffing J, Zecevic M, Heitzmann D, Staub O
  Title
SGK1: aldosterone-induced relay of Na+ transport regulation in distal kidney nephron cells.
  Journal
Cell Physiol Biochem 13:21-8 (2003)
DOI:10.1159/000070246
Reference
PMID:9114008
  Authors
Waldegger S, Barth P, Raber G, Lang F
  Title
Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume.
  Journal
Proc Natl Acad Sci U S A 94:4440-5 (1997)
DOI:10.1073/pnas.94.9.4440
  Sequence
[hsa:6446]
LinkDB

KEGG   ORTHOLOGY: K13303
Entry
K13303                      KO                                     

Name
SGK2
Definition
serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
Pathway
ko04068  FoxO signaling pathway
ko04151  PI3K-Akt signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K13303  SGK2; serum/glucocorticoid-regulated kinase 2
   04151 PI3K-Akt signaling pathway
    K13303  SGK2; serum/glucocorticoid-regulated kinase 2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K13303  SGK2; serum/glucocorticoid-regulated kinase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K13303  SGK2; serum/glucocorticoid-regulated kinase 2
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  SGK family [OT]
   K13303  SGK2; serum/glucocorticoid-regulated kinase 2
Genes
HSA: 10110(SGK2)
PTR: 740699(SGK2)
PPS: 100969822(SGK2)
GGO: 101139934(SGK2)
PON: 100171824(SGK2)
NLE: 100589087(SGK2)
MCC: 695356(SGK2)
MCF: 102120204(SGK2)
CSAB: 103245773(SGK2)
RRO: 104678887(SGK2)
RBB: 108533395(SGK2)
CJC: 100396756(SGK2)
SBQ: 101038785(SGK2)
MMU: 27219(Sgk2)
MCAL: 110284250(Sgk2)
MPAH: 110318250(Sgk2)
RNO: 171497(Sgk2)
MUN: 110548220(Sgk2)
CGE: 100772733(Sgk2)
NGI: 103748372(Sgk2)
HGL: 101717022(Sgk2)
CCAN: 109692501(Sgk2)
OCU: 100352204(SGK2)
TUP: 102496805(SGK2)
CFA: 610835(SGK2)
VVP: 112920093(SGK2)
AML: 100470932(SGK2)
UMR: 103669748(SGK2)
UAH: 113258622(SGK2)
ORO: 101362306(SGK2)
ELK: 111141638
FCA: 101095733(SGK2)
PTG: 102955962(SGK2)
PPAD: 109272422(SGK2)
AJU: 106968942(SGK2)
BTA: 517909(SGK2)
BOM: 102278866(SGK2)
BIU: 109567701(SGK2)
BBUB: 102394498(SGK2)
CHX: 102190431(SGK2)
OAS: 101107121(SGK2)
SSC: 100157757(SGK2)
CFR: 102508180(SGK2)
CDK: 105087124(SGK2)
BACU: 103013234(SGK2)
LVE: 103071415(SGK2)
OOR: 101283340(SGK2)
DLE: 111184161(SGK2)
PCAD: 102992091(SGK2)
ECB: 100070683
EPZ: 103548164(SGK2)
EAI: 106834350(SGK2)
MYD: 102767028(L3MBTL1)
DRO: 112304125(SGK2)
PALE: 102897615(SGK2)
MJV: 108398892(SGK2)
LAV: 100656013(SGK2)
TMU: 101357765
MDO: 100032629(SGK2)
SHR: 100921029(SGK2)
PCW: 110216720(SGK2)
OAA: 100080312(SGK2)
GGA: 419166(SGK2)
MGP: 100546118
CJO: 107322884(SGK2)
NMEL: 110408194(SGK2)
APLA: 101804068(SGK2)
ACYG: 106043491(SGK2)
TGU: 100226841(SGK2)
LSR: 110473166(SGK2)
SCAN: 103818601(SGK2)
GFR: 102031612(SGK2)
FAB: 101813648(SGK2)
PHI: 102102082(SGK2)
PMAJ: 107213394(SGK2)
CCAE: 111938271(SGK2)
CCW: 104687773(SGK2)
ETL: 114060937(SGK2)
FPG: 101916585(SGK2)
FCH: 102049201(SGK2)
CLV: 102089296(SGK2)
EGZ: 104132207(SGK2)
NNI: 104013077(SGK2)
ACUN: 113487591(SGK2)
PADL: 103912404(SGK2)
AAM: 106488186(SGK2)
ASN: 102383702(SGK2)
AMJ: 102559820(SGK2)
PSS: 102463821(SGK2)
CMY: 102935803(SGK2)
CPIC: 101941483(SGK2)
ACS: 100566896(sgk2)
PVT: 110083029(SGK2)
PBI: 103054499(SGK2)
PMUR: 107290466(SGK2)
TSR: 106542640(SGK2)
PMUA: 114599533(SGK2)
GJA: 107124827(SGK2)
XLA: 108704609
XTR: 100036607(sgk2) 100485686
NPR: 108791968(SGK2)
DRE: 570956(sgk2a)
IPU: 108276347(sgk2)
PHYP: 113545576
AMEX: 103045730(sgk2)
EEE: 113572299(sgk2)
TRU: 101062596(sgk2)
LCO: 104936179
NCC: 104943891(sgk2)
MZE: 101478315(sgk2)
ONL: 100711106(sgk2)
OLA: 101162289(sgk2)
XMA: 102222170(sgk2)
XCO: 114147442(sgk2)
PRET: 103468023(sgk2)
CVG: 107086632(sgk2)
NFU: 107390595(sgk2)
KMR: 108236800(sgk2)
ALIM: 106513062(sgk2)
AOCE: 111577689(sgk2)
CSEM: 103384515(sgk2)
POV: 109630569(sgk2)
LCF: 108891669(sgk2)
SDU: 111220523(sgk2)
SLAL: 111670783(sgk2)
HCQ: 109517809(sgk2)
BPEC: 110174711(sgk2)
MALB: 109971140(sgk2)
SASA: 100194914(sgk2) 106571978(SGK2) 106582834
ELS: 105026341(sgk2)
SFM: 108939527(sgk2)
PKI: 111840297(sgk2)
LCM: 102363200(SGK2)
RTP: 109911055(sgk2)
AQU: 100637084
SCE: YKL126W(YPK1) YMR104C(YPK2)
KMX: KLMA_30098(YPK1)
NCS: NCAS_0A04360(NCAS0A04360) NCAS_0F01460(NCAS0F01460)
NDI: NDAI_0H02340(NDAI0H02340) NDAI_0K01370(NDAI0K01370)
TPF: TPHA_0G02480(TPHA0G02480) TPHA_0G02910(TPHA0G02910)
TBL: TBLA_0I01370(TBLA0I01370)
TDL: TDEL_0A02220(TDEL0A02220)
KAF: KAFR_0D03020(KAFR0D03020)
PIC: PICST_65306(YPK2)
CAL: CAALFM_C108540CA(CaO19.399)
SLB: AWJ20_4719(YPK1)
NCR: NCU07280(stk-50)
NTE: NEUTE1DRAFT136721(NEUTE1DRAFT_136721)
MGR: MGG_06599
SSCK: SPSK_08674
CMT: CCM_09293
MBE: MBM_06638
ANI: AN5973.2
ANG: ANI_1_808024(An02g05860)
PTE: PTT_15539
ZTR: MYCGRDRAFT_86313(MgTpk3)
SPO: SPCC24B10.07(gad8)
CNE: CNJ01100
CNB: CNBJ2370
TASA: A1Q1_06414
ABP: AGABI1DRAFT114034(AGABI1DRAFT_114034) AGABI1DRAFT116625(AGABI1DRAFT_116625) AGABI1DRAFT130693(AGABI1DRAFT_130693)
ABV: AGABI2DRAFT114695(AGABI2DRAFT_114695) AGABI2DRAFT193872(AGABI2DRAFT_193872) AGABI2DRAFT195357(AGABI2DRAFT_195357)
MGL: MGL_1165
MRT: MRET_2986
DDI: DDB_G0290157(pkgB)
DFA: DFA_01466 DFA_02499(pkgB) DFA_05853(pkgE_ps)
EHI: EHI_053130(4.t00082)
PTM: GSPATT00000560001 GSPATT00000619001 GSPATT00000926001 GSPATT00001230001 GSPATT00001268001 GSPATT00001870001 GSPATT00002094001 GSPATT00003501001 GSPATT00004152001 GSPATT00004514001 GSPATT00004601001 GSPATT00004764001 GSPATT00005611001 GSPATT00006810001 GSPATT00007028001 GSPATT00007652001 GSPATT00007689001 GSPATT00008134001 GSPATT00008410001 GSPATT00008463001 GSPATT00008497001 GSPATT00008738001 GSPATT00008893001 GSPATT00009502001 GSPATT00009512001 GSPATT00010072001 GSPATT00010120001 GSPATT00011004001 GSPATT00011816001 GSPATT00012931001 GSPATT00014197001 GSPATT00014478001 GSPATT00014962001 GSPATT00015299001 GSPATT00015301001 GSPATT00015702001 GSPATT00016075001 GSPATT00016186001 GSPATT00016635001 GSPATT00017666001 GSPATT00017771001 GSPATT00019217001 GSPATT00020501001 GSPATT00020656001 GSPATT00020863001 GSPATT00021227001 GSPATT00021382001 GSPATT00021531001 GSPATT00021625001 GSPATT00021645001 GSPATT00021843001 GSPATT00022042001 GSPATT00022296001 GSPATT00022804001 GSPATT00023311001 GSPATT00023907001 GSPATT00024274001 GSPATT00024644001 GSPATT00024788001 GSPATT00026274001 GSPATT00026362001 GSPATT00027222001 GSPATT00027355001 GSPATT00027672001 GSPATT00027740001 GSPATT00027796001 GSPATT00028137001 GSPATT00029366001 GSPATT00029443001 GSPATT00029723001 GSPATT00029761001 GSPATT00030525001 GSPATT00030745001 GSPATT00031242001 GSPATT00031701001 GSPATT00032533001 GSPATT00032763001 GSPATT00033682001 GSPATT00034954001 GSPATT00035588001 GSPATT00035666001 GSPATT00036971001 GSPATT00037166001 GSPATT00037818001 GSPATT00038175001 PTMB.04c
SMIN: v1.2.022320.t1(symbB.v1.2.022320.t1)
TCR: 508965.60
 » show all
Reference
  Authors
Friedrich B, Feng Y, Cohen P, Risler T, Vandewalle A, Broer S, Wang J, Pearce D, Lang F
  Title
The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC.
  Journal
Pflugers Arch 445:693-6 (2003)
DOI:10.1007/s00424-002-0993-8
  Sequence
[hsa:10110]
Reference
  Authors
deHart AK, Schnell JD, Allen DA, Hicke L
  Title
The conserved Pkh-Ypk kinase cascade is required for endocytosis in yeast.
  Journal
J Cell Biol 156:241-8 (2002)
DOI:10.1083/jcb.200107135
LinkDB

KEGG   ORTHOLOGY: K13304
Entry
K13304                      KO                                     

Name
SGK3
Definition
serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
Pathway
ko04068  FoxO signaling pathway
ko04151  PI3K-Akt signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K13304  SGK3; serum/glucocorticoid-regulated kinase 3
   04151 PI3K-Akt signaling pathway
    K13304  SGK3; serum/glucocorticoid-regulated kinase 3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K13304  SGK3; serum/glucocorticoid-regulated kinase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K13304  SGK3; serum/glucocorticoid-regulated kinase 3
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  SGK family [OT]
   K13304  SGK3; serum/glucocorticoid-regulated kinase 3
Genes
HSA: 100533105(C8orf44-SGK3) 23678(SGK3)
PTR: 464217
PPS: 100987089(SGK3)
GGO: 101136884
PON: 100174621(SGK3)
NLE: 100586435
MCC: 703700
MCF: 101925870(SGK3)
CSAB: 103236916
RRO: 104668803
RBB: 108544905(SGK3)
CJC: 100387916(C16H8orf44)
SBQ: 101035562
MMU: 170755(Sgk3)
MCAL: 110292472
MPAH: 110338619
RNO: 171498(Sgk3)
MUN: 110552849
CGE: 100767615(Sgk3)
NGI: 103751373
HGL: 101712816(Sgk3)
OCU: 100343709(SGK3)
TUP: 102481125(SGK3)
CFA: 486981(SGK3)
VVP: 112929873
AML: 100475793
UMR: 103677485
UAH: 113268043
ORO: 101363423
ELK: 111155378
FCA: 101095636(SGK3)
PTG: 102968087(SGK3)
PPAD: 109269304(SGK3)
AJU: 106979770(SGK3)
BTA: 504480(SGK3)
BOM: 102271420(SGK3)
BIU: 109568578(SGK3)
BBUB: 102392047
CHX: 102172279(SGK3)
OAS: 101122444
SSC: 100521447
CFR: 102511863
CDK: 105095980
BACU: 103003704(SGK3)
LVE: 103082546(SGK3)
OOR: 101289491
DLE: 111185579
PCAD: 102982053
ECB: 100052030
EPZ: 103555257(SGK3)
EAI: 106829408(SGK3)
MYB: 102251712(SGK3)
MYD: 102756639(SGK3)
MNA: 107532161(SGK3)
HAI: 109375109
DRO: 112315584
PALE: 102889775(SGK3)
RAY: 107514820
MJV: 108407758(SGK3)
LAV: 100674894(SGK3)
TMU: 101343492
MDO: 100029120(SGK3)
SHR: 100918178
PCW: 110219058
OAA: 100079213
GGA: 420167(SGK3)
MGP: 100542838
CJO: 107310235
NMEL: 110393269
APLA: 101800569(SGK3)
ACYG: 106030622
TGU: 100231693(SGK3)
LSR: 110484723
SCAN: 103812575
GFR: 102036813(SGK3)
FAB: 101821448(SGK3)
PHI: 102113475(SGK3)
PMAJ: 107199865
CCAE: 111924677
CCW: 104692837
ETL: 114062809
FPG: 101913504(SGK3)
FCH: 102059079
CLV: 102086726
EGZ: 104122395(SGK3)
NNI: 104018500
ACUN: 113476140
PADL: 103926207
AAM: 106484648
ASN: 102368712
AMJ: 102573167(SGK3)
PSS: 102451137
CMY: 102941738(SGK3)
CPIC: 101950370(SGK3)
ACS: 100565570(sgk3)
PVT: 110089237
PBI: 103052207
PMUR: 107295114
TSR: 106540505
GJA: 107108501
XLA: 108695327(sgk3.S) 108719280(sgk3.L)
XTR: 100491891(sgk3)
NPR: 108785180
DRE: 564523(sgk3)
SGH: 107586697(sgk3) 107590197
IPU: 108256491(sgk3)
PHYP: 113541222(sgk3)
AMEX: 103040639(sgk3)
EEE: 113573866(sgk3)
TRU: 101065298(sgk3)
LCO: 104921584(sgk3)
MZE: 101472799(sgk3)
ONL: 100697141(sgk3)
OLA: 101156366(sgk3)
XMA: 102224026(sgk3)
XCO: 114136852(sgk3)
PRET: 103456598
CVG: 107090815(sgk3)
NFU: 107382892(sgk3)
KMR: 108230471(sgk3)
ALIM: 106513455(sgk3)
AOCE: 111572451(sgk3)
CSEM: 103377124(sgk3)
POV: 109629892
LCF: 108881792
SDU: 111221005(sgk3)
SLAL: 111662994
HCQ: 109530954(sgk3)
BPEC: 110160922(sgk3)
MALB: 109960153(sgk3)
SASA: 106579527 106590407(sgk3)
ELS: 105019586(sgk3)
SFM: 108935537
PKI: 111834824 111861148(sgk3)
LCM: 102345438(SGK3)
CMK: 103180737
BFO: 118409654
CIN: 100182808
APLC: 110985681
SKO: 100367908
API: 100163770
DNX: 107173505
AGS: 114120298
RMD: 113550454
BTAB: 109030344
ZNE: 110828013
DPTE: 113794301
CSCU: 111641299
PTEP: 107442867
PCAN: 112574410
CRG: 105331539
MYI: 110455794
OBI: 106869056
LAK: 106169652
SHX: MS3_03209
NVE: 5509324
EPA: 110233580
DGT: 114525386
HMG: 100215651(sgk3)
AQU: 100640366
 » show all
Reference
  Authors
Friedrich B, Feng Y, Cohen P, Risler T, Vandewalle A, Broer S, Wang J, Pearce D, Lang F
  Title
The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC.
  Journal
Pflugers Arch 445:693-6 (2003)
DOI:10.1007/s00424-002-0993-8
  Sequence
[hsa:23678]
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