KEGG   ORTHOLOGY: K13375
Entry
K13375                      KO                                     

Name
TGFB1
Definition
transforming growth factor beta-1
Pathway
map04010  MAPK signaling pathway
map04060  Cytokine-cytokine receptor interaction
map04068  FoxO signaling pathway
map04110  Cell cycle
map04218  Cellular senescence
map04350  TGF-beta signaling pathway
map04380  Osteoclast differentiation
map04390  Hippo signaling pathway
map04659  Th17 cell differentiation
map04672  Intestinal immune network for IgA production
map04926  Relaxin signaling pathway
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map05140  Leishmaniasis
map05142  Chagas disease
map05144  Malaria
map05145  Toxoplasmosis
map05146  Amoebiasis
map05152  Tuberculosis
map05161  Hepatitis B
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05205  Proteoglycans in cancer
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05220  Chronic myeloid leukemia
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05321  Inflammatory bowel disease
map05323  Rheumatoid arthritis
map05410  Hypertrophic cardiomyopathy
map05414  Dilated cardiomyopathy
map05415  Diabetic cardiomyopathy
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H00434  Camurati-Engelmann disease
H01593  Osteoporosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
   04350 TGF-beta signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
   04390 Hippo signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
   04068 FoxO signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13375  TGFB1; transforming growth factor beta-1
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K13375  TGFB1; transforming growth factor beta-1
   04218 Cellular senescence
    K13375  TGFB1; transforming growth factor beta-1
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K13375  TGFB1; transforming growth factor beta-1
   04672 Intestinal immune network for IgA production
    K13375  TGFB1; transforming growth factor beta-1
  09152 Endocrine system
   04926 Relaxin signaling pathway
    K13375  TGFB1; transforming growth factor beta-1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K13375  TGFB1; transforming growth factor beta-1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K13375  TGFB1; transforming growth factor beta-1
   05205 Proteoglycans in cancer
    K13375  TGFB1; transforming growth factor beta-1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K13375  TGFB1; transforming growth factor beta-1
   05212 Pancreatic cancer
    K13375  TGFB1; transforming growth factor beta-1
   05225 Hepatocellular carcinoma
    K13375  TGFB1; transforming growth factor beta-1
   05226 Gastric cancer
    K13375  TGFB1; transforming growth factor beta-1
   05220 Chronic myeloid leukemia
    K13375  TGFB1; transforming growth factor beta-1
   05211 Renal cell carcinoma
    K13375  TGFB1; transforming growth factor beta-1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K13375  TGFB1; transforming growth factor beta-1
   05161 Hepatitis B
    K13375  TGFB1; transforming growth factor beta-1
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K13375  TGFB1; transforming growth factor beta-1
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K13375  TGFB1; transforming growth factor beta-1
   05144 Malaria
    K13375  TGFB1; transforming growth factor beta-1
   05145 Toxoplasmosis
    K13375  TGFB1; transforming growth factor beta-1
   05140 Leishmaniasis
    K13375  TGFB1; transforming growth factor beta-1
   05142 Chagas disease
    K13375  TGFB1; transforming growth factor beta-1
  09163 Immune disease
   05323 Rheumatoid arthritis
    K13375  TGFB1; transforming growth factor beta-1
   05321 Inflammatory bowel disease
    K13375  TGFB1; transforming growth factor beta-1
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K13375  TGFB1; transforming growth factor beta-1
   05414 Dilated cardiomyopathy
    K13375  TGFB1; transforming growth factor beta-1
   05415 Diabetic cardiomyopathy
    K13375  TGFB1; transforming growth factor beta-1
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K13375  TGFB1; transforming growth factor beta-1
   04933 AGE-RAGE signaling pathway in diabetic complications
    K13375  TGFB1; transforming growth factor beta-1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K13375  TGFB1; transforming growth factor beta-1
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K13375  TGFB1; transforming growth factor beta-1
   00536 Glycosaminoglycan binding proteins
    K13375  TGFB1; transforming growth factor beta-1
Chaperones and folding catalysts [BR:ko03110]
 Intramolecular chaperones
  Others
   K13375  TGFB1; transforming growth factor beta-1
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K13375  TGFB1; transforming growth factor beta-1
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   K13375  TGFB1; transforming growth factor beta-1
Genes
HSA: 7040(TGFB1)
PTR: 456060(TGFB1)
PPS: 100980947(TGFB1)
GGO: 101124474(TGFB1)
PON: 100459982(TGFB1)
NLE: 100581386(TGFB1)
MCC: 106992315(TGFB1)
MCF: 102129546(TGFB1)
CSAB: 103234729(TGFB1)
CATY: 105598017(TGFB1)
PANU: 101006627(TGFB1)
RRO: 104676086(TGFB1)
RBB: 108536158(TGFB1)
TFN: 117075968(TGFB1)
PTEH: 111554142(TGFB1)
CJC: 100401979(TGFB1)
SBQ: 101047980(TGFB1)
MMUR: 105869115(TGFB1)
MMU: 21803(Tgfb1)
MCAL: 110298438(Tgfb1)
MPAH: 110336543(Tgfb1)
RNO: 59086(Tgfb1)
MCOC: 116101857(Tgfb1)
MUN: 110561197(Tgfb1)
CGE: 100773359(Tgfb1)
PLEU: 114685302(Tgfb1)
NGI: 103751514(Tgfb1)
HGL: 101704230(Tgfb1)
CCAN: 109685632(Tgfb1)
TUP: 102488524(TGFB1)
CFA: 403998(TGFB1)
VVP: 112928349(TGFB1)
VLG: 121485274(TGFB1)
AML: 100470703(TGFB1)
UMR: 103677394
UAH: 113243540(TGFB1)
ORO: 101385166(TGFB1)
ELK: 111161420
MPUF: 101670127(TGFB1)
EJU: 114202548(TGFB1)
MLX: 118022632(TGFB1)
FCA: 768263(TGFB1)
PTG: 102951285(TGFB1)
AJU: 106987682(TGFB1)
HHV: 120243258(TGFB1)
BTA: 282089(TGFB1)
BOM: 102283357(TGFB1)
BIU: 109572866(TGFB1)
BBUB: 102413660(TGFB1)
CHX: 102191364(TGFB1)
OAS: 443417(TGFB1)
ODA: 120872413(TGFB1)
SSC: 397078(TGFB1)
CFR: 102509937(TGFB1)
CDK: 105093367(TGFB1)
BACU: 103002687(TGFB1)
LVE: 103075846(TGFB1)
OOR: 101286197(TGFB1)
DLE: 111180824(TGFB1)
PCAD: 102975643(TGFB1)
ECB: 100033900(TGFB1)
EPZ: 103562543(TGFB1)
EAI: 106843812(TGFB1)
MYB: 102262083(TGFB1)
MYD: 102752983(TGFB1)
MMYO: 118674276(TGFB1)
MNA: 107534176(TGFB1)
HAI: 109376590(TGFB1)
DRO: 112320009(TGFB1)
SHON: 118982068(TGFB1)
AJM: 119058462(TGFB1)
MMF: 118638486(TGFB1)
PALE: 102884154(TGFB1)
RAY: 107505490(TGFB1)
MJV: 108383720(TGFB1)
TOD: 119248636 119249350(TGFB1)
LAV: 100667634(TGFB1)
TMU: 101342543
MDO: 100019183(TGFB1)
SHR: 100932607(TGFB1)
PCW: 110202366(TGFB1)
OAA: 114812005(TGFB1)
GGA: 100873157(TGFB1)
PCOC: 116241290
CJO: 107307103(TGFB1)
LSR: 110482796
FAB: 101818496(TGFB1)
PHI: 102112781(TGFB1)
PMAJ: 107198990(TGFB1)
CCAE: 111942551
ASN: 102369002(TGFB1)
AMJ: 102567067(TGFB1)
CMY: 114022153(TGFB1)
CPIC: 101937891(TGFB1)
CABI: 116833884(TGFB1)
ACS: 100553920(tgfb1)
PVT: 110088538(TGFB1)
PBI: 103064413(TGFB1)
PMUR: 107295274(TGFB1)
TSR: 106551445(TGFB1)
PGUT: 117677694(TGFB1)
PMUA: 114603306(TGFB1)
ZVI: 118086683(TGFB1)
GJA: 107123911(TGFB1)
XLA: 108700276(tgfb1.S) 397778(tgfb1.L)
XTR: 100498430(tgfb1)
NPR: 108800768
DRE: 359834(tgfb1a) 563884(tgfb1b)
IPU: 108279384(tgfb1) 108280750(tgfb1)
AMEX: 103024607 103033069(tgfb1)
TRU: 101074275(tgf-beta1)
LCO: 109141681
NCC: 104950840
ELY: 117259934(tgfb1a)
PLEP: 121943219(tgfb1a)
SLUC: 116039943(tgfb1a)
ECRA: 117941999(tgfb1a)
PFLV: 114552362
GAT: 120821525(tgfb1a)
MSAM: 119882881(tgfb1a)
CUD: 121521145(tgfb1a)
MZE: 101473892
ONL: 100694653
OAU: 116320331(tgfb1a)
OLA: 101157631
OML: 112149754(tgfb1a)
XMA: 102216881
XCO: 114161405
XHE: 116707510
PRET: 103475119
CVG: 107103699
CTUL: 119784075(tgfb1a)
NFU: 107379821
KMR: 108228916(tgfb1a)
ALIM: 106529655
AOCE: 111581736
CSEM: 103377845
POV: 109630415
LCF: 108876160
SDU: 111216899
SLAL: 111662255
XGL: 120791875(tgfb1a)
HCQ: 109510758
BPEC: 110163549
MALB: 109963227
SASA: 100136559(TGFB1) 106563563(TGF-beta) 106613337
OMY: 100136774 101268942(tgfb1a) 110534057 118936254(tgfb1a)
LOC: 102698936(tgfb1)
PSPA: 121304906
ARUT: 117394578
LCM: 102364242(TGFB1)
RTP: 109936507
 » show all
Reference
PMID:3470709
  Authors
Derynck R, Rhee L, Chen EY, Van Tilburg A
  Title
Intron-exon structure of the human transforming growth factor-beta precursor gene.
  Journal
Nucleic Acids Res 15:3188-9 (1987)
DOI:10.1093/nar/15.7.3188
  Sequence
[hsa:7040]
LinkDB

KEGG   ORTHOLOGY: K13376
Entry
K13376                      KO                                     

Name
TGFB2
Definition
transforming growth factor beta-2
Pathway
map04010  MAPK signaling pathway
map04060  Cytokine-cytokine receptor interaction
map04068  FoxO signaling pathway
map04110  Cell cycle
map04218  Cellular senescence
map04350  TGF-beta signaling pathway
map04380  Osteoclast differentiation
map04390  Hippo signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map05140  Leishmaniasis
map05142  Chagas disease
map05144  Malaria
map05145  Toxoplasmosis
map05146  Amoebiasis
map05152  Tuberculosis
map05161  Hepatitis B
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05220  Chronic myeloid leukemia
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05321  Inflammatory bowel disease
map05323  Rheumatoid arthritis
map05410  Hypertrophic cardiomyopathy
map05414  Dilated cardiomyopathy
map05415  Diabetic cardiomyopathy
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H00800  Loeys-Dietz syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
   04350 TGF-beta signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
   04390 Hippo signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
   04068 FoxO signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13376  TGFB2; transforming growth factor beta-2
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K13376  TGFB2; transforming growth factor beta-2
   04218 Cellular senescence
    K13376  TGFB2; transforming growth factor beta-2
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K13376  TGFB2; transforming growth factor beta-2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K13376  TGFB2; transforming growth factor beta-2
   05206 MicroRNAs in cancer
    K13376  TGFB2; transforming growth factor beta-2
   05205 Proteoglycans in cancer
    K13376  TGFB2; transforming growth factor beta-2
  09162 Cancer: specific types
   05210 Colorectal cancer
    K13376  TGFB2; transforming growth factor beta-2
   05212 Pancreatic cancer
    K13376  TGFB2; transforming growth factor beta-2
   05225 Hepatocellular carcinoma
    K13376  TGFB2; transforming growth factor beta-2
   05226 Gastric cancer
    K13376  TGFB2; transforming growth factor beta-2
   05220 Chronic myeloid leukemia
    K13376  TGFB2; transforming growth factor beta-2
   05211 Renal cell carcinoma
    K13376  TGFB2; transforming growth factor beta-2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K13376  TGFB2; transforming growth factor beta-2
   05161 Hepatitis B
    K13376  TGFB2; transforming growth factor beta-2
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K13376  TGFB2; transforming growth factor beta-2
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K13376  TGFB2; transforming growth factor beta-2
   05144 Malaria
    K13376  TGFB2; transforming growth factor beta-2
   05145 Toxoplasmosis
    K13376  TGFB2; transforming growth factor beta-2
   05140 Leishmaniasis
    K13376  TGFB2; transforming growth factor beta-2
   05142 Chagas disease
    K13376  TGFB2; transforming growth factor beta-2
  09163 Immune disease
   05323 Rheumatoid arthritis
    K13376  TGFB2; transforming growth factor beta-2
   05321 Inflammatory bowel disease
    K13376  TGFB2; transforming growth factor beta-2
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K13376  TGFB2; transforming growth factor beta-2
   05414 Dilated cardiomyopathy
    K13376  TGFB2; transforming growth factor beta-2
   05415 Diabetic cardiomyopathy
    K13376  TGFB2; transforming growth factor beta-2
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K13376  TGFB2; transforming growth factor beta-2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K13376  TGFB2; transforming growth factor beta-2
   00536 Glycosaminoglycan binding proteins
    K13376  TGFB2; transforming growth factor beta-2
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K13376  TGFB2; transforming growth factor beta-2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   K13376  TGFB2; transforming growth factor beta-2
Genes
HSA: 7042(TGFB2)
PTR: 457742(TGFB2)
PPS: 100985755(TGFB2)
GGO: 101125504(TGFB2)
PON: 100461291(TGFB2)
NLE: 100596183(TGFB2)
MCC: 707540(TGFB2)
MCF: 101925182(TGFB2)
CSAB: 103230082(TGFB2)
CATY: 105577004(TGFB2)
PANU: 101009253(TGFB2)
RRO: 104662252(TGFB2)
RBB: 108528282(TGFB2)
TFN: 117074794(TGFB2)
PTEH: 111537117(TGFB2)
CJC: 100390586(TGFB2)
SBQ: 101044624(TGFB2)
MMUR: 105868760(TGFB2)
MMU: 21808(Tgfb2)
MCAL: 110292955(Tgfb2)
MPAH: 110321649(Tgfb2)
RNO: 81809(Tgfb2)
MCOC: 116068447(Tgfb2)
MUN: 110549244(Tgfb2)
CGE: 100774918(Tgfb2)
PLEU: 114698210(Tgfb2)
NGI: 103728817(Tgfb2)
HGL: 101707457(Tgfb2)
CCAN: 109698650(Tgfb2)
OCU: 100009371(TGFB2)
TUP: 102500482(TGFB2)
CFA: 488596(TGFB2)
VVP: 112914338(TGFB2)
VLG: 121471376(TGFB2)
AML: 100463584(TGFB2)
UMR: 103658194(TGFB2)
UAH: 113268733(TGFB2)
ORO: 101380860(TGFB2)
ELK: 111151068
MPUF: 101677182(TGFB2)
EJU: 114210508(TGFB2)
MLX: 118014087(TGFB2)
FCA: 101093414(TGFB2)
PTG: 102951894(TGFB2)
PPAD: 109276581(TGFB2)
AJU: 106979500(TGFB2)
HHV: 120221741(TGFB2)
BTA: 534069(TGFB2)
BOM: 102283491(TGFB2)
BIU: 109570509(TGFB2)
BBUB: 102390629(TGFB2)
CHX: 100861228(TGFB2)
OAS: 554322(TGFB2)
ODA: 120880130(TGFB2)
SSC: 397084(TGFB2)
CFR: 102505811(TGFB2)
CDK: 105100091(TGFB2)
BACU: 103001453(TGFB2)
LVE: 103070826(TGFB2)
OOR: 101276254(TGFB2)
DLE: 111177477(TGFB2)
PCAD: 102993033(TGFB2)
ECB: 100050377(TGFB2) 111771316
EPZ: 103543045(TGFB2)
EAI: 106836714(TGFB2)
MYB: 102250887(TGFB2)
MYD: 102755920(TGFB2)
MMYO: 118678846(TGFB2)
MNA: 107543622(TGFB2)
HAI: 109381205(TGFB2)
DRO: 112318906(TGFB2)
SHON: 119003169(TGFB2)
AJM: 119045813(TGFB2)
MMF: 118640680(TGFB2)
PALE: 102881295(TGFB2)
RAY: 107520844(TGFB2)
MJV: 108403151(TGFB2)
TOD: 119234883(TGFB2)
LAV: 100656534(TGFB2)
TMU: 101347669
MDO: 100017548(TGFB2)
SHR: 100914910(TGFB2)
PCW: 110205565(TGFB2)
OAA: 100080176(TGFB2)
GGA: 421352(TGFB2)
PCOC: 116230622(TGFB2)
MGP: 100549559(TGFB2)
CJO: 107311051(TGFB2)
NMEL: 110395798(TGFB2)
APLA: 101794148(TGFB2)
ACYG: 106031565(TGFB2)
TGU: 100231617(TGFB2)
LSR: 110479104(TGFB2)
SCAN: 103821503(TGFB2)
PMOA: 120496994(TGFB2)
GFR: 102037698(TGFB2)
FAB: 101814341(TGFB2)
PHI: 102114598(TGFB2)
PMAJ: 107202393(TGFB2)
CCAE: 111926211(TGFB2)
CCW: 104685626(TGFB2)
ETL: 114064354(TGFB2)
FPG: 101917357(TGFB2)
FCH: 102047778(TGFB2)
CLV: 102085196(TGFB2)
EGZ: 104133428(TGFB2)
NNI: 104019653(TGFB2)
ACUN: 113478516(TGFB2)
PADL: 103916133(TGFB2)
AAM: 106490440(TGFB2)
ASN: 102382227(TGFB2)
AMJ: 102562163(TGFB2)
CPOO: 109319735(TGFB2)
GGN: 109296861(TGFB2)
PSS: 102452874(TGFB2)
CMY: 102946116(TGFB2)
CPIC: 101945771(TGFB2)
TST: 117874463(TGFB2)
CABI: 116828212(TGFB2)
ACS: 100568228(tgfb2)
PVT: 110083352 110087066(TGFB2)
PBI: 103063485(TGFB2) 103067099
PMUR: 107293669(TGFB2) 107299193
TSR: 106538869(TGFB2) 106539344
PGUT: 117671719(TGFB2)
PMUA: 114586591 114594660(TGFB2)
ZVI: 118076237 118083182(TGFB2)
GJA: 107110247(TGFB2) 107115203
XLA: 108717706(tgfb2.S) 373801(tgfb2.L)
XTR: 100489680(tgfb2)
NPR: 108795797(TGFB2)
DRE: 369194(tgfb2) 559723(tgfb2l)
IPU: 108268908 108269996(tgfb2)
PHYP: 113526787(tgfb2) 113528823
AMEX: 103026112(tgfb2) 103042476
EEE: 113572191(tgfb2) 113581676
LCO: 104925539 104936633(tgfb2)
NCC: 104945388
ELY: 117251444(tgfb5) 117264719(tgfb2)
PLEP: 121946355(tgfb2) 121947966(tgfb5)
SLUC: 116052623(tgfb5) 116064582(tgfb2)
ECRA: 117946043(tgfb2) 117951661(tgfb5)
PFLV: 114557393(tgfb2) 114562717
GAT: 120810593(tgfb2) 120817123(tgfb5)
MSAM: 119889077(tgfb5) 119896887(tgfb2)
CUD: 121515929(tgfb5)
MZE: 101466107 101469764(tgfb2)
ONL: 100690458 100707856(tgfb2)
OAU: 116317211(tgfb5) 116327679(tgfb2)
OLA: 101155037
OML: 112152993(tgfb5)
XMA: 102223216
XCO: 114139436
XHE: 116714966
PRET: 103471446(tgfb2)
CVG: 107087932(tgfb2)
CTUL: 119784511(tgfb5)
NFU: 107377547
KMR: 108231423(tgfb5)
ALIM: 106515824
AOCE: 111569136(tgfb2) 111576372
CSEM: 103388748(tgfb2) 103390834
POV: 109631969(tgfb2) 109642431
LCF: 108872574 108886089(tgfb2)
SDU: 111227872(tgfb2) 111232504
SLAL: 111655785 111664155(tgfb2)
XGL: 120784280(tgfb2) 120784927(tgfb5)
HCQ: 109511954 109521921(tgfb2)
BPEC: 110158948 110159085(tgfb2)
MALB: 109956839 109973033(tgfb2)
OMY: 110489077(tgfb5) 110490140 110519367(tgfb2)
ELS: 105007294(tgfb2) 105026733
SFM: 108925415 108929121(tgfb2)
PKI: 111835201 111851556(tgfb2)
LOC: 102682814 102683493(tgfb2)
LCM: 102352268 102358422(TGFB2)
CMK: 103172825 103185816(tgfb2)
RTP: 109911779(tgfb2)
CIN: 778780(tgfbeta2)
SKO: 100329003(TGFbeta2)
VDE: 111249885
VJA: 111273048
PDAM: 113671019
AQU: 105312053
 » show all
Reference
  Authors
Chen YG
  Title
Endocytic regulation of TGF-beta signaling.
  Journal
Cell Res 19:58-70 (2009)
DOI:10.1038/cr.2008.315
Reference
  Authors
Singla DK, Sun B
  Title
Transforming growth factor-beta2 enhances differentiation of cardiac myocytes from embryonic stem cells.
  Journal
Biochem Biophys Res Commun 332:135-41 (2005)
DOI:10.1016/j.bbrc.2005.04.098
  Sequence
[hsa:7042]
Reference
PMID:3322813
  Authors
de Martin R, Haendler B, Hofer-Warbinek R, Gaugitsch H, Wrann M, Schlusener H, Seifert JM, Bodmer S, Fontana A, Hofer E
  Title
Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.
  Journal
EMBO J 6:3673-7 (1987)
DOI:10.1002/j.1460-2075.1987.tb02700.x
  Sequence
[hsa:7042]
LinkDB

KEGG   ORTHOLOGY: K13377
Entry
K13377                      KO                                     

Name
TGFB3
Definition
transforming growth factor beta-3
Pathway
map04010  MAPK signaling pathway
map04060  Cytokine-cytokine receptor interaction
map04068  FoxO signaling pathway
map04110  Cell cycle
map04218  Cellular senescence
map04350  TGF-beta signaling pathway
map04390  Hippo signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map05140  Leishmaniasis
map05142  Chagas disease
map05144  Malaria
map05145  Toxoplasmosis
map05146  Amoebiasis
map05152  Tuberculosis
map05161  Hepatitis B
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05220  Chronic myeloid leukemia
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05321  Inflammatory bowel disease
map05323  Rheumatoid arthritis
map05410  Hypertrophic cardiomyopathy
map05414  Dilated cardiomyopathy
map05415  Diabetic cardiomyopathy
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H00293  Arrhythmogenic right ventricular cardiomyopathy
H00431  Ossification of the posterior longitudinal ligament of spine
H00800  Loeys-Dietz syndrome
H01385  Rienhoff syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
   04350 TGF-beta signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
   04390 Hippo signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
   04068 FoxO signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13377  TGFB3; transforming growth factor beta-3
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K13377  TGFB3; transforming growth factor beta-3
   04218 Cellular senescence
    K13377  TGFB3; transforming growth factor beta-3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K13377  TGFB3; transforming growth factor beta-3
  09162 Cancer: specific types
   05210 Colorectal cancer
    K13377  TGFB3; transforming growth factor beta-3
   05212 Pancreatic cancer
    K13377  TGFB3; transforming growth factor beta-3
   05225 Hepatocellular carcinoma
    K13377  TGFB3; transforming growth factor beta-3
   05226 Gastric cancer
    K13377  TGFB3; transforming growth factor beta-3
   05220 Chronic myeloid leukemia
    K13377  TGFB3; transforming growth factor beta-3
   05211 Renal cell carcinoma
    K13377  TGFB3; transforming growth factor beta-3
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K13377  TGFB3; transforming growth factor beta-3
   05161 Hepatitis B
    K13377  TGFB3; transforming growth factor beta-3
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K13377  TGFB3; transforming growth factor beta-3
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K13377  TGFB3; transforming growth factor beta-3
   05144 Malaria
    K13377  TGFB3; transforming growth factor beta-3
   05145 Toxoplasmosis
    K13377  TGFB3; transforming growth factor beta-3
   05140 Leishmaniasis
    K13377  TGFB3; transforming growth factor beta-3
   05142 Chagas disease
    K13377  TGFB3; transforming growth factor beta-3
  09163 Immune disease
   05323 Rheumatoid arthritis
    K13377  TGFB3; transforming growth factor beta-3
   05321 Inflammatory bowel disease
    K13377  TGFB3; transforming growth factor beta-3
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K13377  TGFB3; transforming growth factor beta-3
   05414 Dilated cardiomyopathy
    K13377  TGFB3; transforming growth factor beta-3
   05415 Diabetic cardiomyopathy
    K13377  TGFB3; transforming growth factor beta-3
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K13377  TGFB3; transforming growth factor beta-3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K13377  TGFB3; transforming growth factor beta-3
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K13377  TGFB3; transforming growth factor beta-3
Genes
HSA: 7043(TGFB3)
PTR: 453054(TGFB3)
PPS: 100990987(TGFB3)
GGO: 101133741(TGFB3)
PON: 100433208(TGFB3)
NLE: 100591391(TGFB3)
MCC: 703239(TGFB3)
MCF: 102119907(TGFB3)
CSAB: 103229367(TGFB3)
CATY: 105590879(TGFB3)
PANU: 100997116(TGFB3)
RRO: 104677599(TGFB3)
RBB: 108534939(TGFB3)
TFN: 117069299(TGFB3)
PTEH: 111555026(TGFB3)
CJC: 100392463(TGFB3)
SBQ: 101048819(TGFB3)
MMUR: 105858956(TGFB3)
MMU: 21809(Tgfb3)
MCAL: 110306834(Tgfb3)
MPAH: 110324521(Tgfb3)
RNO: 25717(Tgfb3)
MCOC: 116080097(Tgfb3)
MUN: 110558214(Tgfb3)
CGE: 100756831(Tgfb3)
PLEU: 114697904(Tgfb3)
NGI: 103739777(Tgfb3)
HGL: 101712904(Tgfb3)
CCAN: 109686152(Tgfb3)
OCU: 100358982(TGFB3)
TUP: 102497029(TGFB3)
CFA: 490796(TGFB3)
VVP: 112927298(TGFB3)
VLG: 121493196(TGFB3)
AML: 100475861(TGFB3)
UMR: 103670922(TGFB3)
UAH: 113270312(TGFB3)
ORO: 101364584(TGFB3)
ELK: 111148592
MPUF: 101678400(TGFB3)
EJU: 114207516(TGFB3)
MLX: 118002625(TGFB3)
FCA: 101098469(TGFB3)
PTG: 102949760(TGFB3)
PPAD: 109253865(TGFB3)
AJU: 106974351(TGFB3)
HHV: 120231992(TGFB3)
BTA: 538957(TGFB3)
BOM: 102265567(TGFB3)
BIU: 109565371(TGFB3)
BBUB: 102389416(TGFB3)
CHX: 102189962(TGFB3)
OAS: 554323(TGFB3)
ODA: 120852691(TGFB3)
SSC: 397400(TGFB3)
CFR: 102517948(TGFB3)
CDK: 105086078(TGFB3)
BACU: 103001029(TGFB3)
LVE: 103086562(TGFB3)
OOR: 101289027(TGFB3)
DLE: 111176232(TGFB3)
PCAD: 102977345(TGFB3)
ECB: 100051765(TGFB3)
EPZ: 103555506(TGFB3)
EAI: 106830938(TGFB3)
MYB: 102249502(TGFB3)
MYD: 102767291(TGFB3)
MMYO: 118658350(TGFB3)
MNA: 107533843(TGFB3)
HAI: 109381619(TGFB3)
DRO: 112311221(TGFB3)
SHON: 118976756(TGFB3)
AJM: 119049266(TGFB3)
MMF: 118633354(TGFB3)
PALE: 102893304(TGFB3)
RAY: 107498899(TGFB3)
MJV: 108404608(TGFB3)
TOD: 119239348(TGFB3)
LAV: 100653832(TGFB3)
TMU: 101358028
MDO: 100017937(TGFB3)
SHR: 100929617(TGFB3)
PCW: 110208305(TGFB3)
OAA: 100074840(TGFB3)
GGA: 396438(TGFB3)
PCOC: 116228975(TGFB3)
MGP: 100544554(TGFB3) 109364721
CJO: 107315120(TGFB3)
NMEL: 110401408(TGFB3)
APLA: 101802287(TGFB3)
ACYG: 106038869(TGFB3)
TGU: 100232487(TGFB3)
LSR: 110477235(TGFB3)
PMOA: 120500429(TGFB3)
GFR: 102037028(TGFB3)
FAB: 101809258(TGFB3)
PHI: 102102248(TGFB3)
PMAJ: 107205526(TGFB3)
CCAE: 111929961(TGFB3)
CCW: 104685280(TGFB3)
ETL: 114056022(TGFB3)
FPG: 101912650(TGFB3)
FCH: 102055453(TGFB3)
CLV: 102088125(TGFB3)
EGZ: 104133279(TGFB3)
NNI: 104020998(TGFB3)
ACUN: 113480465(TGFB3)
PADL: 103912969(TGFB3)
AAM: 106482877(TGFB3)
ASN: 102384560(TGFB3)
AMJ: 102563668(TGFB3)
CPOO: 109320856(TGFB3)
GGN: 109299319(TGFB3)
PSS: 102456369(TGFB3)
CMY: 102929710(TGFB3)
CPIC: 101941121(TGFB3)
TST: 117876373(TGFB3)
CABI: 116837512(TGFB3)
ACS: 100551709(tgfb3)
PVT: 110079121(TGFB3)
PBI: 103061116(TGFB3)
PMUR: 107285957(TGFB3)
TSR: 106545079(TGFB3)
PGUT: 117665844(TGFB3)
PMUA: 114591728(TGFB3)
ZVI: 118081749(TGFB3)
GJA: 107116455(TGFB3)
DRE: 369195(tgfb3)
SRX: 107723269 107724242(tgfb3)
SANH: 107688075 107702240(tgfb3)
SGH: 107554783(tgfb3)
IPU: 108270130(tgfb3)
PHYP: 113538920(tgfb3)
AMEX: 103032923(tgfb3)
EEE: 113585931(tgfb3)
TRU: 101065117(tgfb3) 101077955
LCO: 104921351(tgfb3) 104922426
NCC: 104943712(tgfb3) 104964434
ELY: 117267019(tgfb3) 117270870
PLEP: 121953311(tgfb3) 121955433
SLUC: 116035577(tgfb3) 116066112
ECRA: 117935617(tgfb3) 117961404
PFLV: 114546436(tgfb3) 114573007
GAT: 120807995 120832683(tgfb3)
MSAM: 119909133 119910740(tgfb3)
CUD: 121521710 121526006(tgfb3)
ONL: 100710008 100712568(tgfb3)
OAU: 116313325(tgfb3) 116314093
OLA: 101155815 101165927(tgfb3)
OML: 112157680 112162206(tgfb3)
XMA: 102221990(tgfb3) 102223288
XCO: 114134077(tgfb3) 114158174
XHE: 116708847(tgfb3) 116734514
PRET: 103457593 103459051(tgfb3)
CVG: 107083120 107092398(tgfb3)
CTUL: 119785110 119787547(tgfb3)
NFU: 107377518 107392404(tgfb3)
KMR: 108235253(tgfb3) 108242427
ALIM: 106520481(tgfb3) 106525282
POV: 109628154(tgfb3) 109636158
LCF: 108892510(tgfb3) 108895683
SDU: 111225435(tgfb3) 111238468
SLAL: 111653047 111663127(tgfb3)
XGL: 120789452 120795080(tgfb3)
HCQ: 109507757(tgfb3)
BPEC: 110153435 110155280(tgfb3)
MALB: 109955077(tgfb3) 109969998
ELS: 105015709(tgfb3) 105029941
SFM: 108930719(tgfb3) 108936661
PKI: 111844437 111852442(tgfb3)
LOC: 102691880(tgfb3)
PSPA: 121324804 121329880(tgfb3)
LCM: 102358543(TGFB3)
RTP: 109921206(tgfb3)
BFO: 118430343
APLC: 110979251
DSV: 119433276
ATEN: 116300211
 » show all
Reference
PMID:3164476
  Authors
ten Dijke P, Hansen P, Iwata KK, Pieler C, Foulkes JG
  Title
Identification of another member of the transforming growth factor type beta gene family.
  Journal
Proc Natl Acad Sci U S A 85:4715-9 (1988)
DOI:10.1073/pnas.85.13.4715
  Sequence
[hsa:7043]
Reference
  Authors
Bocharov EV, Korzhnev DM, Blommers MJ, Arvinte T, Orekhov VY, Billeter M, Arseniev AS
  Title
Dynamics-modulated biological activity of transforming growth factor beta3.
  Journal
J Biol Chem 277:46273-9 (2002)
DOI:10.1074/jbc.M206274200
  Sequence
[hsa:7043]
Reference
PMID:3208746
  Authors
Derynck R, Lindquist PB, Lee A, Wen D, Tamm J, Graycar JL, Rhee L, Mason AJ, Miller DA, Coffey RJ, et al.
  Title
A new type of transforming growth factor-beta, TGF-beta 3.
  Journal
EMBO J 7:3737-43 (1988)
DOI:10.1002/j.1460-2075.1988.tb03257.x
  Sequence
[hsa:7043]
LinkDB

DBGET integrated database retrieval system