KEGG   ORTHOLOGY: K13769Help
Entry
K13769                      KO                                     

Name
IGF2
Definition
insulin-like growth factor 2
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04151  PI3K-Akt signaling pathway
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05225  Hepatocellular carcinoma
Disease
H00033  Adrenal carcinoma
H00048  Hepatocellular carcinoma
H00711  Russell-Silver syndrome
H00713  Beckwith-Wiedemann syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K13769  IGF2; insulin-like growth factor 2
   04010 MAPK signaling pathway
    K13769  IGF2; insulin-like growth factor 2
   04151 PI3K-Akt signaling pathway
    K13769  IGF2; insulin-like growth factor 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K13769  IGF2; insulin-like growth factor 2
   05205 Proteoglycans in cancer
    K13769  IGF2; insulin-like growth factor 2
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K13769  IGF2; insulin-like growth factor 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K13769  IGF2; insulin-like growth factor 2
   00536 Glycosaminoglycan binding proteins
    K13769  IGF2; insulin-like growth factor 2
Cytokines and growth factors [BR:ko04052]
 Growth factors
  Growth factors (RTK binding)
   K13769  IGF2; insulin-like growth factor 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Growth factors/receptors
   K13769  IGF2; insulin-like growth factor 2
BRITE hierarchy
Other DBs
GO: 0005159
Genes
HSA: 3481(IGF2)
PTR: 742381(IGF2)
PPS: 100968468(IGF2)
GGO: 101133471(IGF2)
PON: 100453365(IGF2)
NLE: 100585821(IGF2)
MCC: 710802(IGF2)
MCF: 102126663(IGF2)
CSAB: 103239180(IGF2)
RRO: 104677104(IGF2)
RBB: 108539209(IGF2)
CJC: 100393815(IGF2)
SBQ: 101036519(IGF2)
MMU: 16002(Igf2)
MCAL: 110298427(Igf2)
MPAH: 110316402(Igf2)
RNO: 24483(Igf2)
MUN: 110546690(Igf2)
CGE: 100762359(Igf2)
NGI: 103738988(Igf2)
HGL: 101720309(Igf2)
CCAN: 109689792(Igf2)
OCU: 100328792(IGF2)
TUP: 102481608(IGF2)
CFA: 483664(IGF2)
VVP: 112924139(IGF2)
AML: 100483184(IGF2)
UMR: 103671055(IGF2)
UAH: 113243959(IGF2)
ORO: 101384061(IGF2)
FCA: 101093644(IGF2)
AJU: 113595529(IGF2)
BTA: 281240(IGF2)
BOM: 102274689(IGF2)
BIU: 109554335(IGF2)
BBUB: 102395378(IGF2)
PHD: 102344174(IGF2)
CHX: 100861277(IGF2)
OAS: 443325(IGF2)
SSC: 396916(IGF2)
CFR: 102515540(IGF2)
CDK: 105106402(IGF2)
BACU: 102997276(IGF2)
LVE: 103084737(IGF2)
OOR: 101278742(IGF2)
DLE: 111183604(IGF2)
ECB: 100034182(IGF2)
EPZ: 103567613(IGF2)
EAI: 106824098(IGF2)
MYB: 102247355(IGF2)
MNA: 107539909(IGF2)
HAI: 109395935(IGF2)
RSS: 109435671(IGF2) 109442997
DRO: 112317267(IGF2)
PALE: 102880410(IGF2)
LAV: 100664990(IGF2)
SHR: 100928068(IGF2)
PCW: 110197133(IGF2)
OAA: 791102(IGF2)
GGA: 395097(IGF2)
MGP: 100303676(IGF2)
CJO: 107314538(IGF2)
APLA: 101799111(IGF2)
ACYG: 106042580(IGF2)
TGU: 100218445(IGF2)
LSR: 110468650(IGF2)
SCAN: 103826753(IGF2)
GFR: 102032627(IGF2)
FAB: 101812363(IGF2)
PHI: 102111387(IGF2)
PMAJ: 107206324(IGF2)
CCAE: 111930776(IGF2)
CCW: 104687627(IGF2)
ETL: 114059841(IGF2)
FPG: 101915916(IGF2)
FCH: 102057742(IGF2)
CLV: 102094702(IGF2)
EGZ: 104124918(IGF2)
NNI: 104010403(IGF2)
ACUN: 113481190(IGF2)
AAM: 106496994(IGF2)
ASN: 102378893(IGF2)
AMJ: 102565996(IGF2)
PSS: 102445459(IGF2)
CMY: 102935902(IGF2)
CPIC: 101937814(IGF2)
ACS: 100565807(igf2)
PVT: 110076544(IGF2)
PBI: 103061017(IGF2)
PMUR: 107299015(IGF2)
GJA: 107123375(IGF2)
XLA: 108697782 398240(igf2.S) 398245(igf3.L) 432206(igf2.L)
XTR: 100134992(igf2) 100145502(igf3)
NPR: 108791995(IGF2) 108800079
DRE: 30710(igf2a) 324215(igf2b)
IPU: 100304637 100528676(igf2)
TRU: 100462940(igf2)
LCO: 109140778(igf2)
NCC: 104966228(igf2)
MZE: 101468736(igf2)
OLA: 101172047(igf2)
XMA: 102222127(igf2)
XCO: 114158858(igf2)
PRET: 103466159(igf2)
NFU: 107389021(igf2)
KMR: 108237538(igf2)
CSEM: 103380367(igf2)
LCF: 108875327(igf2)
SDU: 111228384(igf2)
HCQ: 109530494(igf2)
BPEC: 110165965(igf2)
MALB: 109967897(igf2)
SASA: 100136550(IGF-II) 106572168
OTW: 112218392
SALP: 111961991
ELS: 105005983
LCM: 102347414 102348010(IGF2)
LHU: 105675058
BMOR: 100169715(Bbx-b10) 100169716(Bbx-b7) 100169719(Bbx-b1) 100169720(Bbx-b4) 100169721(Bbx-b2) 100169723(Bbx-b6)
DNX: 107162072
PCAN: 112566539
MYI: 110452351
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Constancia M, Hemberger M, Hughes J, Dean W, Ferguson-Smith A, Fundele R, Stewart F, Kelsey G, Fowden A, Sibley C, Reik W
  Title
Placental-specific IGF-II is a major modulator of placental and fetal growth.
  Journal
Nature 417:945-8 (2002)
DOI:10.1038/nature00819
Reference
PMID:9722981
  Authors
O'Dell SD, Day IN
  Title
Insulin-like growth factor II (IGF-II).
  Journal
Int J Biochem Cell Biol 30:767-71 (1998)
DOI:10.1016/S1357-2725(98)00048-X
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