KEGG   ORTHOLOGY: K14349
Entry
K14349                      KO                                     

Name
NCEH1, AADACL1
Definition
neutral cholesterol ester hydrolase 1 [EC:3.1.1.-]
Pathway
ko04927  Cortisol synthesis and secretion
ko04934  Cushing syndrome
ko04976  Bile secretion
ko04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    K14349  NCEH1, AADACL1; neutral cholesterol ester hydrolase 1
  09154 Digestive system
   04976 Bile secretion
    K14349  NCEH1, AADACL1; neutral cholesterol ester hydrolase 1
   04979 Cholesterol metabolism
    K14349  NCEH1, AADACL1; neutral cholesterol ester hydrolase 1
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K14349  NCEH1, AADACL1; neutral cholesterol ester hydrolase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K14349  NCEH1, AADACL1; neutral cholesterol ester hydrolase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.-  
     K14349  NCEH1, AADACL1; neutral cholesterol ester hydrolase 1
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S9: prolyl oligopeptidase family
   K14349  NCEH1, AADACL1; neutral cholesterol ester hydrolase 1
Genes
HSA: 57552(NCEH1)
PTR: 470998(NCEH1)
PPS: 100988456(NCEH1)
GGO: 101132015(NCEH1)
PON: 100172976(NCEH1)
NLE: 100580453(NCEH1)
MCC: 694200(NCEH1)
MCF: 101867255(NCEH1)
CSAB: 103221242(NCEH1)
RRO: 104657163(NCEH1)
RBB: 108540417(NCEH1)
CJC: 100395412(NCEH1)
SBQ: 101030595(NCEH1)
MMU: 320024(Nceh1)
MCAL: 110291251(Nceh1)
MPAH: 110321005(Nceh1)
RNO: 294930(Nceh1)
MUN: 110558664(Nceh1)
CGE: 100756133(Nceh1)
NGI: 103739880(Nceh1)
HGL: 101703160(Nceh1)
CCAN: 109683464(Nceh1)
OCU: 100341189(NCEH1)
TUP: 102493014(NCEH1)
CFA: 488171(NCEH1)
VVP: 112926697(NCEH1)
AML: 100465000(NCEH1)
UMR: 103676138(NCEH1)
UAH: 113254997(NCEH1)
ORO: 101371746(NCEH1)
ELK: 111149950
FCA: 101082846(NCEH1)
PTG: 102963612(NCEH1)
PPAD: 109275140(NCEH1)
AJU: 106990056(NCEH1)
BTA: 534212(NCEH1)
BOM: 102287389(NCEH1)
BIU: 109558001(NCEH1)
BBUB: 102402958(NCEH1)
CHX: 102173042(NCEH1)
OAS: 101113553(NCEH1)
SSC: 100154209(NCEH1)
CFR: 102506408(NCEH1)
CDK: 105085941(NCEH1)
BACU: 103021143(NCEH1)
LVE: 103083075(NCEH1) 103083289
OOR: 101282318(NCEH1)
DLE: 111173945(NCEH1)
PCAD: 102976073(NCEH1)
ECB: 100064432(NCEH1)
EPZ: 103546355(NCEH1)
EAI: 106847538(NCEH1)
MYB: 102261543(NCEH1)
MYD: 102752271(NCEH1)
MNA: 107533528(NCEH1)
HAI: 109371670(NCEH1)
DRO: 112307538(NCEH1)
PALE: 102885919(NCEH1)
RAY: 107516337(NCEH1)
MJV: 108387456(NCEH1)
LAV: 100668092(NCEH1)
TMU: 101359651
MDO: 100010391(NCEH1)
SHR: 100929735(NCEH1)
PCW: 110204182(NCEH1)
OAA: 100089722(NCEH1)
GGA: 429158(NCEH1)
MGP: 100549988(NCEH1)
CJO: 107318305(NCEH1)
NMEL: 110397395(NCEH1)
APLA: 101798674(NCEH1)
ACYG: 106032001(NCEH1)
TGU: 100232669(NCEH1)
LSR: 110480342(NCEH1)
SCAN: 103815596(NCEH1)
GFR: 102042617(NCEH1)
FAB: 101805934(NCEH1)
PHI: 102100487(NCEH1)
PMAJ: 107208923(NCEH1)
CCAE: 111933594(NCEH1)
CCW: 104688033(NCEH1)
ETL: 114061179(NCEH1)
FPG: 101911827(NCEH1)
FCH: 102051095(NCEH1)
CLV: 102093153(NCEH1)
EGZ: 104132498(NCEH1)
NNI: 104022071(NCEH1)
ACUN: 113483362(NCEH1)
PADL: 103924982(NCEH1)
AAM: 106486597(NCEH1)
ASN: 102370787(NCEH1)
AMJ: 102577201(NCEH1)
PSS: 102461028(NCEH1)
CMY: 102946036(NCEH1)
CPIC: 101932253(NCEH1)
ACS: 100566353(nceh1)
PVT: 110079049(NCEH1)
PBI: 103068277(NCEH1)
PMUR: 107286547(NCEH1)
TSR: 106547750(NCEH1)
PMUA: 114597988(NCEH1)
GJA: 107113862(NCEH1)
XLA: 100101305(nceh1.S) 108717005(nceh1.L)
XTR: 493371(nceh1)
NPR: 108784831(NCEH1)
DRE: 432374(nceh1a) 777713(nceh1b.1) 797436
CCAR: 109059539
IPU: 108261838(nceh1) 108278037(NCEH1)
PHYP: 113524391 113541233(nceh1)
AMEX: 103023841(nceh1) 103029691
EEE: 113576102(nceh1) 113576493
LCO: 104920042 104939799(nceh1)
PRET: 103456719 103458423(nceh1)
CVG: 107085113(nceh1) 107103201
NFU: 107383106 107392067(nceh1)
ALIM: 106511398 106525541(nceh1)
AOCE: 111563447 111576220(nceh1)
CSEM: 103377513 103378966(nceh1)
SDU: 111225577 111238321(nceh1)
MALB: 109961055 109969611(nceh1)
LCM: 102346217(NCEH1)
CMK: 103175755(nceh1)
RTP: 109915153(nceh1)
CBR: CBG16012
PCAN: 112554313
LAK: 106162233
 » show all
Reference
  Authors
Zhao B, Natarajan R, Ghosh S
  Title
Human liver cholesteryl ester hydrolase: cloning, molecular characterization, and role in cellular cholesterol homeostasis.
  Journal
Physiol Genomics 23:304-10 (2005)
DOI:10.1152/physiolgenomics.00187.2005
  Sequence
[hsa:57552]
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