KEGG   ORTHOLOGY: K14369
Entry
K14369                      KO                                     

Name
eryG
Definition
erythromycin 3''-O-methyltransferase [EC:2.1.1.254]
Pathway
ko00522  Biosynthesis of 12-, 14- and 16-membered macrolides
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00774  Erythromycin biosynthesis, propanoyl-CoA + methylmalonyl-CoA => deoxyerythronolide B => erythromycin A/B
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K14369  eryG; erythromycin 3''-O-methyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K14369  eryG; erythromycin 3''-O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.254  erythromycin 3''-O-methyltransferase
     K14369  eryG; erythromycin 3''-O-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Methylase
   K14369  eryG; erythromycin 3''-O-methyltransferase
Other DBs
RN: R05520 R05532
Genes
AER: AERYTH_15890
SEN: SACE_0728(eryG)
Reference
PMID:1840640
  Authors
Haydock SF, Dowson JA, Dhillon N, Roberts GA, Cortes J, Leadlay PF
  Title
Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases.
  Journal
Mol Gen Genet 230:120-8 (1991)
DOI:10.1007/BF00290659
  Sequence
[sen:SACE_0728]
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