KEGG   ORTHOLOGY: K14465
Entry
K14465                      KO                                     

Name
K14465
Definition
succinate semialdehyde reductase (NADPH) [EC:1.1.1.-]
Pathway
ko00720  Carbon fixation pathways in prokaryotes
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00374  Dicarboxylate-hydroxybutyrate cycle
M00375  Hydroxypropionate-hydroxybutylate cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Carbon fixation pathways in prokaryotes
    K14465  K14465; succinate semialdehyde reductase (NADPH)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-  
     K14465  K14465; succinate semialdehyde reductase (NADPH)
Other DBs
RN: R09281
Genes
LPIL: LIP_2864
ROA: Pd630_LPD07337
GOR: KTR9_4592
GTA: BCM27_24145
DIT: C3V38_00360
DIZ: CT688_10230
DPC: A6048_10575
DLU: A6035_10085
SRJ: SRO_1586
MLV: CVS47_02985
PFRE: RM25_1821
SEN: SACE_1391
AHE: Arch_0038
TPYO: X956_00825
STO: STK_20560(ssr)
SSO: SSO0472(adh-1)
SOL: Ssol_1454
SSOA: SULA_1497
SSOL: SULB_1498
SSOF: SULC_1496
SAI: Saci_2145(adh)
SID: M164_1679
SII: LD85_1888
SIH: SiH_1606
SIR: SiRe_1527
SIC: SiL_1519
MSE: Msed_1424
MCN: Mcup_0811
AHO: Ahos_2277
STEP: IC006_1473
PIS: Pisl_0251
PCL: Pcal_1391
PYR: P186_0714
TNE: Tneu_0419
TTN: TTX_1106
TUZ: TUZN_0945
 » show all
Reference
  Authors
Berg IA, Kockelkorn D, Buckel W, Fuchs G
  Title
A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea.
  Journal
Science 318:1782-6 (2007)
DOI:10.1126/science.1149976
Reference
  Authors
Ramos-Vera WH, Berg IA, Fuchs G
  Title
Autotrophic carbon dioxide assimilation in Thermoproteales revisited.
  Journal
J Bacteriol 191:4286-97 (2009)
DOI:10.1128/JB.00145-09
LinkDB

KEGG   ORTHOLOGY: K18121
Entry
K18121                      KO                                     

Name
GLYR
Definition
glyoxylate/succinic semialdehyde reductase [EC:1.1.1.79 1.1.1.-]
Pathway
ko00630  Glyoxylate and dicarboxylate metabolism
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K18121  GLYR; glyoxylate/succinic semialdehyde reductase
   00650 Butanoate metabolism
    K18121  GLYR; glyoxylate/succinic semialdehyde reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.79  glyoxylate reductase (NADP+)
     K18121  GLYR; glyoxylate/succinic semialdehyde reductase
    1.1.1.-  
     K18121  GLYR; glyoxylate/succinic semialdehyde reductase
Other DBs
RN: R00465 R01392 R09281
Genes
AAG: 110675196
ATH: AT1G17650(GLYR2) AT3G25530(GLYR1)
ALY: 9321794 9329023
CRB: 17892502 17900051
CSAT: 104740463 104747092 104756097 104766463 104775879 104790215
EUS: EUTSA_v10002631mg EUTSA_v10008217mg
BRP: 103828609 103872547
BNA: 106346856 106367684 106430323 106447268
BOE: 106295360 106321159
RSZ: 108835198 108856805 108856833
THJ: 104808825
LJA: Lj3g3v0323280.1(Lj3g3v0323280.1) Lj3g3v2387600.1(Lj3g3v2387600.1)
PXB: 103944427
SLY: 100147724(SSR1) 100147725(SSR2)
DOSA: Os01t0574600-01(Os01g0574600) Os02t0562700-01(Os02g0562700)
ATS: 109737508(LOC109737508) 109750521(LOC109750521)
DCT: 110097871
PEQ: 110018475
APRO: F751_5526
NGD: NGA_0545500(MMSB)
PIN: Ping_3356
GUR: Gura_0588
GBM: Gbem_0351(ghr)
GEB: GM18_0428
PPD: Ppro_2197
DES: DSOUD_0196(ghr)
AAC: Aaci_1877
AAD: TC41_1975
TACI: TDSAC_0791
OTE: Oter_1928
AMU: Amuc_1944
GFL: GRFL_3267
 » show all
Reference
  Authors
Breitkreuz KE, Allan WL, Van Cauwenberghe OR, Jakobs C, Talibi D, Andre B, Shelp BJ
  Title
A novel gamma-hydroxybutyrate dehydrogenase: identification and expression of an Arabidopsis cDNA and potential role under oxygen deficiency.
  Journal
J Biol Chem 278:41552-6 (2003)
DOI:10.1074/jbc.M305717200
  Sequence
[ath:AT3G25530]
Reference
  Authors
Ching SL, Gidda SK, Rochon A, van Cauwenberghe OR, Shelp BJ, Mullen RT
  Title
Glyoxylate reductase isoform 1 is localized in the cytosol and not peroxisomes in plant cells.
  Journal
J Integr Plant Biol 54:152-68 (2012)
DOI:10.1111/j.1744-7909.2012.01103.x
  Sequence
[ath:AT3G25530]
Reference
  Authors
Simpson JP, Di Leo R, Dhanoa PK, Allan WL, Makhmoudova A, Clark SM, Hoover GJ, Mullen RT, Shelp BJ
  Title
Identification and characterization of a plastid-localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification.
  Journal
J Exp Bot 59:2545-54 (2008)
DOI:10.1093/jxb/ern123
  Sequence
[ath:AT1G17650]
LinkDB

KEGG   ORTHOLOGY: K00043
Entry
K00043                      KO                                     

Name
gbd
Definition
4-hydroxybutyrate dehydrogenase [EC:1.1.1.61]
Pathway
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
ko01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    K00043  gbd; 4-hydroxybutyrate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.61  4-hydroxybutyrate dehydrogenase
     K00043  gbd; 4-hydroxybutyrate dehydrogenase
Other DBs
RN: R01644
GO: 0047577
Genes
PMK: MDS_0271
PPF: Pput_2157
PPG: PputGB1_3155
PPB: PPUBIRD1_3027
PPI: YSA_00253
PPX: T1E_2653(dhaT)
PPUT: L483_10705
PPUN: PP4_31900(gbd)
POR: APT59_05510
PVR: PverR02_11545
PSIL: PMA3_16430
PALL: UYA_00985
CSA: Csal_1756
HEL: HELO_1042
AXE: P40_19220
RSO: RSc1771(gbd1) RSp0986(gbd2)
RSN: RSPO_c01807(gbd1) RSPO_m01535(gbd2)
RSY: RSUY_19640(dhaT_1) RSUY_45330(dhaT_2)
RPI: Rpic_1435
REH: H16_A1553(gbd)
CNC: CNE_1c15720(gbd1) CNE_2c21420(dhaT)
CGD: CR3_1469(gbd)
BMA: BMA0905
BMAL: DM55_2122
BMAE: DM78_2160
BMAQ: DM76_2097
BMAI: DM57_2961
BMAF: DM51_660
BMAZ: BM44_2344
BMAB: BM45_1909
BPS: BPSL2002
BPM: BURPS1710b_1823(gbd1)
BPSE: BDL_538
BPSM: BBQ_1873
BPSU: BBN_1999
BPSD: BBX_2477
BPK: BBK_48
BPSH: DR55_3113
BPSA: BBU_708
BPSO: X996_2727
BUT: X994_1181
BTE: BTH_I2655
BTQ: BTQ_1369
BTJ: BTJ_1083
BTZ: BTL_2324
BTD: BTI_2398
BTV: BTHA_2523
BTHE: BTN_2444
BTHM: BTRA_2604
BTHA: DR62_2589
BTHL: BG87_2548
BOK: DM82_940
BOC: BG90_3662
BUL: BW21_2365
BXE: Bxe_A1316
BXB: DR64_3477
BPH: Bphy_1609
PPNO: DA70_12605
PPNM: LV28_18090
PPUL: RO07_03920
PSPU: NA29_15990
CABA: SBC2_25090(dhaT_1)
BPAR: BN117_1237(gbd)
BPA: BPP2084(gbd)
BBH: BN112_1980(gbd)
BBR: BB1480(gbd)
BBM: BN115_1435(gbd)
BBX: BBS798_1441(gbd)
ODI: ODI_R3947
POL: Bpro_2526
PNA: Pnap_1943
AAV: Aave_3418
AJS: Ajs_1711
AAA: Acav_1813
DAC: Daci_3383
CTES: O987_09340
RTA: Rta_19890
LIM: L103DPR2_01788(dhaT_2)
LIH: L63ED372_01374(dhaT)
HYB: Q5W_09540
HPSE: HPF_11925(mdh2)
CBAA: SRAA_1594
CBAB: SMCB_1500
MPT: Mpe_A1798
HSE: Hsero_0146(gbd)
HRB: Hrubri_0160(gbd)
RGE: RGE_26150
MXA: MXAN_5629
CCX: COCOR_06119(dhaT)
MES: Meso_4502
AVI: Avi_6101
BRS: S23_32850
SNO: Snov_3495
MET: M446_3465
MNO: Mnod_0063
MAQU: Maq22A_1p34110(eutG) Maq22A_c07255(eutG)
PHL: KKY_2679
RBM: TEF_19965
TSV: DSM104635_00837(gbsB)
KVL: KVU_0808(gbd)
CID: P73_4768
LABT: FIU93_02600(dhaT1)
HNE: HNE_0174(gbd)
SHUM: STHU_13550
LMOI: VV02_02230
SESP: BN6_54060
IPA: Isop_0941
SACI: Sinac_0778
PBOR: BSF38_02758(adhB)
AGV: OJF2_08320(dhaT_1)
 » show all
Reference
PMID:7851418
  Authors
Valentin HE, Zwingmann G, Schonebaum A, Steinbuchel A
  Title
Metabolic pathway for biosynthesis of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from 4-hydroxybutyrate by Alcaligenes eutrophus.
  Journal
Eur J Biochem 227:43-60 (1995)
DOI:10.1111/j.1432-1033.1995.tb20358.x
  Sequence
LinkDB

KEGG   ORTHOLOGY: K08318
Entry
K08318                      KO                                     

Name
yihU
Definition
4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase [EC:1.1.1.61 1.1.1.373]
Pathway
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
ko01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    K08318  yihU; 4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.61  4-hydroxybutyrate dehydrogenase
     K08318  yihU; 4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase
    1.1.1.373  sulfolactaldehyde 3-reductase
     K08318  yihU; 4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase
Other DBs
RN: R01644 R10719
COG: COG2084
GO: 0047577 0061596
Genes
ECO: b3882(yihU)
ECJ: JW3853(yihU)
ECD: ECDH10B_4072(yihU)
EBW: BWG_3552(yihU)
ECOK: ECMDS42_3321(yihU)
ECE: Z5420(yihU)
ECS: ECs4805
ECF: ECH74115_5329
ETW: ECSP_4938(yihU)
ELX: CDCO157_4544
EOI: ECO111_4702(yihU)
EOJ: ECO26_4708(yihU)
EOH: ECO103_4289(yihU)
ESL: O3K_24495
ESO: O3O_00840
ESM: O3M_24415
EOK: G2583_4683(yihU)
ELH: ETEC_4152
ECP: ECP_4088
ENA: ECNA114_3975(yihU)
ECOS: EC958_4354(yihU)
ECY: ECSE_4165
ECR: ECIAI1_4082(yihU)
ECQ: ECED1_4582(yihU)
EUM: ECUMN_4409(yihU)
ECT: ECIAI39_3118(yihU)
EOC: CE10_4546(yihU)
EBR: ECB_03767(yihU)
EBL: ECD_03767(yihU)
EBE: B21_03716(yihU)
EBD: ECBD_4145
ECI: UTI89_C4463(yihU)
ECC: c4826(yihU)
ESE: ECSF_3733
EKF: KO11_03195(yihU)
EDJ: ECDH1ME8569_3753(yihU)
ELW: ECW_m4186(yihU)
ELL: WFL_20395(yihU)
ELC: i14_4419(yihU)
ELD: i02_4419(yihU)
ELF: LF82_610
ECOI: ECOPMV1_04237(garR_4)
ECOJ: P423_21510
ESZ: FEM44_09220(yihU)
STY: STY3855(yihU)
STT: t3598(yihU)
STM: STM4023(yihU)
SEO: STM14_4836(yihU)
SEY: SL1344_3969(yihU)
SEJ: STMUK_4006(yihU)
SEB: STM474_4200(yihU)
SEF: UMN798_4360(yihU)
SENR: STMDT2_38831(yihU)
SEND: DT104_40301(yihU)
SENI: CY43_21025
SPT: SPA3864(yihU)
SEK: SSPA3594
SEI: SPC_4126(yihU)
SEC: SCH_3913(yihU)
SHB: SU5_0119
SENS: Q786_19720
SED: SeD_A4411
SEG: SG3402(yihU)
SEL: SPUL_3649(yihU)
SEGA: SPUCDC_3635(yihU)
SET: SEN3811(yihU)
SENA: AU38_19695
SENO: AU37_19710
SENV: AU39_19730
SENQ: AU40_22020
SENL: IY59_20190
SEEP: I137_17525
SENE: IA1_19550
SBG: SBG_3540(yihU)
SBZ: A464_4064
SFL: SF3954(yihU)
SFX: S3792(yihU)
SFV: SFV_3617(yihU)
SFE: SFxv_4308(yihU)
SFN: SFy_5649
SFS: SFyv_5712
SFT: NCTC1_04280(yihU)
SSN: SSON_4048(yihU)
SBO: SBO_3887(yihU)
ENC: ECL_05103
ECLX: LI66_22510
ECLY: LI62_24595
ECLZ: LI64_21625
ECLO: ENC_00300
EEC: EcWSU1_04480(yihU)
ECHG: FY206_24275(yihU)
EBG: FAI37_07030(yihU)
ESA: ESA_04058
CSK: ES15_0037
CTU: CTU_41740(yihU)
CRO: ROD_38791
CKO: CKO_03131
CPOT: FOB25_10635(yihU)
CAMA: F384_21000
LER: GNG29_22755(yihU)
LEA: GNG26_22095(yihU)
AHN: NCTC12129_04955(garR_2)
YAL: AT01_41
RAA: Q7S_20720
PAM: PANA_3497(yihU)
PLF: PANA5342_0554(yihU)
PAJ: PAJ_2726(yihU)
PSTW: DSJ_21395
MTHI: C7M52_01008(yihU)
LRI: NCTC12151_00811(Hgd)
BFN: OI25_3878
BBR: BB4070
RBM: TEF_16385
PSF: PSE_2341(garR)
RID: RIdsm_01292(hgd_4)
SPKC: KC8_02205
SHUM: STHU_22030
SVC: STVA_25540(garR)
HTQ: FRZ44_48020(yihU)
VG: 26040587(APL44_gp022)
 » show all
Reference
  Authors
Saito N, Robert M, Kochi H, Matsuo G, Kakazu Y, Soga T, Tomita M
  Title
Metabolite profiling reveals YihU as a novel hydroxybutyrate dehydrogenase for alternative succinic semialdehyde metabolism in Escherichia coli.
  Journal
J Biol Chem 284:16442-51 (2009)
DOI:10.1074/jbc.M109.002089
Reference
  Authors
Denger K, Weiss M, Felux AK, Schneider A, Mayer C, Spiteller D, Huhn T, Cook AM, Schleheck D
  Title
Sulphoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulphur cycle.
  Journal
Nature 507:114-7 (2014)
DOI:10.1038/nature12947
  Sequence
[eco:b3882]
LinkDB

KEGG   ORTHOLOGY: K18120
Entry
K18120                      KO                                     

Name
4hbD, abfH
Definition
4-hydroxybutyrate dehydrogenase [EC:1.1.1.61]
Pathway
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
ko01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    K18120  4hbD, abfH; 4-hydroxybutyrate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.61  4-hydroxybutyrate dehydrogenase
     K18120  4hbD, abfH; 4-hydroxybutyrate dehydrogenase
Other DBs
RN: R01644
GO: 0047577
Genes
LNG: BSQ50_05330
CAC: CA_C1574
CAE: SMB_G1599(4hbD)
CAY: CEA_G1589
CPE: CPE0539
CPF: CPF_0518
CPR: CPR_0507
CBE: Cbei_4933
CBZ: Cbs_4933
CKL: CKL_3014(4hbD)
CKR: CKR_2662
CLJ: CLJU_c38930(4hbD)
CSQ: CSCA_3619
CTYK: CTK_C07610(4hbD)
CDF: CD630_23380(4hbD)
PDC: CDIF630_02577(gbd)
CDC: CD196_2181(abfH)
CDL: CDR20291_2227(abfH)
PDF: CD630DERM_23380(4hbD)
PHX: KGNDJEFE_01613(mdh)
MED: MELS_0336
EBM: SG0102_24860(4hbD)
BDE: BDP_2141(adh2)
BDN: BBDE_2011
BTP: D805_1109
GVG: HMPREF0421_21009(4hbD)
PGI: PG_0689(4hbD)
PGN: PGN_0724
PGT: PGTDC60_1814(4hbD)
PCRE: NCTC12858_01804(adhB)
PCAG: NCTC12856_01247(eutG)
TFO: BFO_1487
 » show all
Reference
PMID:7606170
  Authors
Wolff RA, Kenealy WR
  Title
Purification and characterization of the oxygen-sensitive 4-hydroxybutanoate dehydrogenase from Clostridium kluyveri.
  Journal
Protein Expr Purif 6:206-12 (1995)
DOI:10.1006/prep.1995.1026
LinkDB

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