KEGG   ORTHOLOGY: K14468Help
Entry
K14468                      KO                                     

Name
mcr
Definition
malonyl-CoA reductase / 3-hydroxypropionate dehydrogenase (NADP+) [EC:1.2.1.75 1.1.1.298]
Pathway
ko00640  Propanoate metabolism
ko00720  Carbon fixation pathways in prokaryotes
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00376  3-Hydroxypropionate bi-cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    K14468  mcr; malonyl-CoA reductase / 3-hydroxypropionate dehydrogenase (NADP+)
  09102 Energy metabolism
   00720 Carbon fixation pathways in prokaryotes
    K14468  mcr; malonyl-CoA reductase / 3-hydroxypropionate dehydrogenase (NADP+)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.298  3-hydroxypropionate dehydrogenase (NADP+)
     K14468  mcr; malonyl-CoA reductase / 3-hydroxypropionate dehydrogenase (NADP+)
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.75  malonyl-CoA reductase (malonate semialdehyde-forming)
     K14468  mcr; malonyl-CoA reductase / 3-hydroxypropionate dehydrogenase (NADP+)
BRITE hierarchy
Other DBs
RN: R00740 R09289
GO: 0035527
Genes
RRS: RoseRS_3201
RCA: Rcas_2929
CAU: Caur_2614
CHL: Chy400_2826
CAG: Cagg_1256
CTM: Cabther_B0159
TaxonomyKoalaUniProt
Reference
  Authors
Zarzycki J, Brecht V, Muller M, Fuchs G
  Title
Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus.
  Journal
Proc Natl Acad Sci U S A 106:21317-22 (2009)
DOI:10.1073/pnas.0908356106
Reference
  Authors
Hugler M, Menendez C, Schagger H, Fuchs G
  Title
Malonyl-coenzyme A reductase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO(2) fixation.
  Journal
J Bacteriol 184:2404-10 (2002)
DOI:10.1128/JB.184.9.2404-2410.2002
  Sequence
[cau:Caur_2614]
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