K14714                      KO                                     

solute carrier family 39 (zinc transporter), member 8
ko04216  Ferroptosis
H00119  Congenital disorders of glycosylation type II
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    K14714  SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K14714  SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC39: Metal ion transporter
   K14714  SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
Other DBs
GO: 0005385
TC: 2.A.5.4.8 2.A.5.4.15
HSA: 64116(SLC39A8)
PTR: 461405(SLC39A8)
PPS: 100978566(SLC39A8)
GGO: 101147092(SLC39A8)
PON: 100171966(SLC39A8)
NLE: 100582544(SLC39A8)
MCC: 710142(SLC39A8)
MCF: 102137377(SLC39A8)
CSAB: 103236046(SLC39A8)
RRO: 104662314(SLC39A8)
RBB: 108532819(SLC39A8)
CJC: 100385303(SLC39A8)
SBQ: 101035154(SLC39A8)
MMU: 67547(Slc39a8)
MCAL: 110290845(Slc39a8)
MPAH: 110320285(Slc39a8)
RNO: 295455(Slc39a8)
MUN: 110562611(Slc39a8)
CGE: 100767442(Slc39a8)
NGI: 103728035(Slc39a8)
HGL: 101713325(Slc39a8)
CCAN: 109675700(Slc39a8)
OCU: 100351178(SLC39A8)
TUP: 102502956(SLC39A8)
CFA: 478494(SLC39A8)
VVP: 112908379(SLC39A8)
AML: 100470583(SLC39A8)
UMR: 103677987(SLC39A8)
UAH: 113263102(SLC39A8)
ORO: 101370996(SLC39A8)
ELK: 111156218
FCA: 101096887(SLC39A8)
PTG: 102951767(SLC39A8)
PPAD: 109247369(SLC39A8)
AJU: 106984698(SLC39A8)
BTA: 508193(SLC39A8)
BOM: 102287443(SLC39A8)
BIU: 109560298(SLC39A8)
BBUB: 102413959(SLC39A8)
CHX: 102182487(SLC39A8)
OAS: 101108488(SLC39A8)
SSC: 100524695(SLC39A8)
CFR: 102505646(SLC39A8)
CDK: 105089557(SLC39A8)
BACU: 103004766(SLC39A8)
LVE: 103068373(SLC39A8)
OOR: 101279349(SLC39A8)
DLE: 111179109(SLC39A8)
PCAD: 102994939(SLC39A8)
ECB: 100067821(SLC39A8)
EPZ: 103556718(SLC39A8)
EAI: 106825954(SLC39A8)
MYB: 102255760(SLC39A8)
MYD: 102754372(SLC39A8)
MNA: 107545486(SLC39A8)
DRO: 112317859(SLC39A8)
PALE: 102880280(SLC39A8)
RAY: 107517910(SLC39A8)
MJV: 108391708(SLC39A8)
LAV: 100674152(SLC39A8)
TMU: 101351603
MDO: 100014598(SLC39A8)
SHR: 100917883(SLC39A8)
PCW: 110209685(SLC39A8)
OAA: 100073920(SLC39A8)
GGA: 430411(SLC39A8)
MGP: 100547628(SLC39A8)
CJO: 107313654(SLC39A8)
NMEL: 110398429(SLC39A8)
APLA: 101802996(SLC39A8)
ACYG: 106045307(SLC39A8)
TGU: 100217712(SLC39A8)
LSR: 110471150(SLC39A8)
SCAN: 103826266(SLC39A8)
GFR: 102036794(SLC39A8)
FAB: 101815328(SLC39A8)
PHI: 102110184(SLC39A8)
PMAJ: 107203510(SLC39A8)
CCAE: 111928327(SLC39A8)
CCW: 104697285(SLC39A8)
ETL: 114068167(SLC39A8)
FPG: 101920184(SLC39A8)
FCH: 102049637(SLC39A8)
CLV: 102086264(SLC39A8)
EGZ: 104122597(SLC39A8)
NNI: 104021324(SLC39A8)
ACUN: 113479680(SLC39A8)
PADL: 103919559(SLC39A8)
AAM: 106491828(SLC39A8)
ASN: 102370497(SLC39A8)
AMJ: 102566753(SLC39A8)
PSS: 102457379(SLC39A8)
CMY: 102933344(SLC39A8)
CPIC: 101936280(SLC39A8)
ACS: 100555224(slc39a8)
PVT: 110085337(SLC39A8)
PBI: 103057537(SLC39A8)
PMUR: 107298992(SLC39A8)
TSR: 106548336(SLC39A8)
PMUA: 114604316(SLC39A8)
GJA: 107105759(SLC39A8)
XLA: 108706737(slc39a8.S) 108710800(slc39a8.L)
XTR: 100487145(slc39a8)
NPR: 108789055(SLC39A8)
DRE: 100002893(slc39a8)
IPU: 108263549 108277197(slc39a8)
PHYP: 113543974 113546963(slc39a8)
TRU: 101069036
MZE: 101466283
ONL: 102076192(slc39a8)
OLA: 101159549(slc39a8)
XMA: 102230222(slc39a8)
XCO: 114134609(slc39a8)
PRET: 103458197
CVG: 107096797
NFU: 107391880(slc39a8)
ALIM: 106536672
AOCE: 111578757(slc39a8)
CSEM: 103381431(slc39a8)
POV: 109636290(slc39a8)
LCF: 108876629(slc39a8)
SDU: 111225479
SLAL: 111672801
HCQ: 109528149
BPEC: 110157422(slc39a8)
MALB: 109962409(slc39a8)
SASA: 106591239
SALP: 112071969
ELS: 105015842(slc39a8)
PKI: 111833171(slc39a8) 111853943
LCM: 102364396(SLC39A8)
CMK: 103177624(slc39a8)
API: 100164672
AGS: 114125785
RMD: 113561254
CLEC: 106670214
ZNE: 110836010
FCD: 110858015
DPTE: 113792008
TSP: Tsp_05260
MYI: 110445450
 » show all
Begum NA, Kobayashi M, Moriwaki Y, Matsumoto M, Toyoshima K, Seya T
Mycobacterium bovis BCG cell wall and lipopolysaccharide induce a novel gene, BIGM103, encoding a 7-TM protein: identification of a new protein family having Zn-transporter and Zn-metalloprotease signatures.
Genomics 80:630-45 (2002)

K14720                      KO                                     

SLC39A14, ZIP14
solute carrier family 39 (zinc transporter), member 14
ko04216  Ferroptosis
H01938  Hypermanganesemia with dystonia
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    K14720  SLC39A14, ZIP14; solute carrier family 39 (zinc transporter), member 14
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K14720  SLC39A14, ZIP14; solute carrier family 39 (zinc transporter), member 14
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC39: Metal ion transporter
   K14720  SLC39A14, ZIP14; solute carrier family 39 (zinc transporter), member 14
Other DBs
GO: 0005385
TC: 2.A.5.4.5
HSA: 23516(SLC39A14)
PTR: 464044(SLC39A14)
PPS: 100977282(SLC39A14)
GGO: 101134955(SLC39A14)
PON: 100172692(SLC39A14)
NLE: 100596898(SLC39A14)
MCC: 716112(SLC39A14)
MCF: 102121052(SLC39A14)
CSAB: 103215453(SLC39A14)
RRO: 104663965(SLC39A14)
RBB: 108540789(SLC39A14)
CJC: 100387296(SLC39A14)
SBQ: 101044319(SLC39A14)
MMU: 213053(Slc39a14)
MCAL: 110309206(Slc39a14)
MPAH: 110325482(Slc39a14)
RNO: 306009(Slc39a14)
MUN: 110551664(Slc39a14)
CGE: 100768099(Slc39a14)
NGI: 103747852(Slc39a14)
HGL: 101717982(Slc39a14)
CCAN: 109690448(Slc39a14)
OCU: 100353576(SLC39A14)
TUP: 102503139(SLC39A14)
CFA: 486124(SLC39A14)
VVP: 112926819(SLC39A14)
AML: 100472331(SLC39A14)
UMR: 103673319(SLC39A14)
UAH: 113270002(SLC39A14)
ORO: 101384512(SLC39A14)
ELK: 111157452
FCA: 101087988(SLC39A14)
PTG: 102948590(SLC39A14)
PPAD: 109277351(SLC39A14)
AJU: 106981115(SLC39A14)
BTA: 515437(SLC39A14)
BOM: 102286469(SLC39A14)
BIU: 109563106(SLC39A14)
BBUB: 102407602(SLC39A14)
CHX: 102174119(SLC39A14)
OAS: 101116017(SLC39A14)
SSC: 100152468(SLC39A14)
CFR: 102515916(SLC39A14)
CDK: 105102658(SLC39A14)
BACU: 103009736(SLC39A14)
LVE: 103070257(SLC39A14)
OOR: 101270783(SLC39A14)
DLE: 111168988(SLC39A14)
PCAD: 102996182(SLC39A14)
EPZ: 103552774(SLC39A14)
EAI: 106847713(SLC39A14)
MYB: 102255981(SLC39A14)
MYD: 102753756(SLC39A14)
MNA: 107536109(SLC39A14)
HAI: 109382473(SLC39A14)
DRO: 112304948(SLC39A14)
PALE: 102898226(SLC39A14)
RAY: 107509228(SLC39A14)
MJV: 108393195(SLC39A14)
LAV: 100665119(SLC39A14)
TMU: 101360340
MDO: 100033103(SLC39A14)
SHR: 100915037(SLC39A14)
PCW: 110200407(SLC39A14)
OAA: 100087458(SLC39A14)
GGA: 429550(SLC39A14)
MGP: 100551133(SLC39A14)
CJO: 107307313(SLC39A14)
NMEL: 110391320
APLA: 101794487(SLC39A14)
ACYG: 106049201(SLC39A14)
TGU: 100219649(SLC39A14)
LSR: 110479427(SLC39A14)
SCAN: 103824436(SLC39A14)
GFR: 102039907(SLC39A14)
FAB: 101807618(SLC39A14)
PHI: 102099841(SLC39A14)
PMAJ: 107213971(SLC39A14)
CCAE: 111938824(SLC39A14)
CCW: 104694839(SLC39A14)
ETL: 114070079(SLC39A14)
FPG: 101917676(SLC39A14)
FCH: 102051982(SLC39A14)
CLV: 102094255(SLC39A14)
EGZ: 104127931(SLC39A14)
NNI: 104019552(SLC39A14)
ACUN: 113490862(SLC39A14)
PADL: 103921518(SLC39A14)
AAM: 106499980(SLC39A14)
ASN: 102372901(SLC39A14)
AMJ: 102575837(SLC39A14)
PSS: 102446011(SLC39A14)
CMY: 102944462(SLC39A14)
CPIC: 101941154(SLC39A14)
ACS: 100551962(slc39a14)
PVT: 110072174(SLC39A14)
PBI: 103052384(SLC39A14)
PMUR: 107289246(SLC39A14)
TSR: 106539735(SLC39A14)
PMUA: 114585211(SLC39A14)
GJA: 107112989(SLC39A14)
XLA: 108711619(slc39a14.L) 108712699(slc39a14.S)
XTR: 100038282(slc39a14)
NPR: 108792815(SLC39A14)
DRE: 799782(slc39a14)
SRX: 107707824 107755875(slc39a14)
IPU: 108255751(slc39a14)
PHYP: 113537098(slc39a14)
AMEX: 103025206(slc39a14)
EEE: 113588536(slc39a14)
TRU: 101062206
LCO: 104935496(slc39a14)
NCC: 104959785
MZE: 101464144
ONL: 100698478
OLA: 101159804(slc39a14)
XMA: 102227820(slc39a14)
XCO: 114154139(slc39a14)
PRET: 103469789(slc39a14)
CVG: 107095932(slc39a14)
NFU: 107386092(slc39a14)
KMR: 108244526(slc39a14)
ALIM: 106525450(slc39a14)
AOCE: 111565776(slc39a14)
CSEM: 103396889 103397726(slc39a14)
POV: 109643832(slc39a14)
LCF: 108891355
SDU: 111227344
SLAL: 111660898
HCQ: 109526898
BPEC: 110172475(slc39a14)
MALB: 109951146(slc39a14)
SASA: 106570872(slc39a14)
OTW: 112262537
SALP: 111957826
ELS: 105029831
SFM: 108929538(slc39a14)
PKI: 111857490(slc39a14)
LCM: 102360991(SLC39A14)
CMK: 103187825(slc39a14)
RTP: 109912397(slc39a14)
CIN: 100182828
SPU: 763759
SKO: 100373486
BTAB: 109031528
ZNE: 110831261
FCD: 110858108
PVM: 113822799
TUT: 107368767
PTEP: 107449242
CEL: CELE_Y55F3BL.2(zipt-15)
CRG: 105318169
OBI: 106879150
SHX: MS3_08092
NVE: 5508879
EPA: 110254188
ADF: 107345861
AMIL: 114954476
PDAM: 113666445
SPIS: 111331739
 » show all
Tuschl K, Meyer E, Valdivia LE, Zhao N, Dadswell C, Abdul-Sada A, Hung CY, Simpson MA, Chong WK, Jacques TS, Woltjer RL, Eaton S, Gregory A, Sanford L, Kara E, Houlden H, Cuno SM, Prokisch H, Valletta L, Tiranti V, Younis R, Maher ER, Spencer J, Straatman-Iwanowska A, Gissen P, Selim LA, Pintos-Morell G, Coroleu-Lletget W, Mohammad SS, Yoganathan S, Dale RC, Thomas M, Rihel J, Bodamer OA, Enns CA, Hayflick SJ, Clayton PT, Mills PB, Kurian MA, Wilson SW
Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia.
Nat Commun 7:11601 (2016)

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