KEGG   ORTHOLOGY: K14964
Entry
K14964                      KO                                     

Name
ASH2
Definition
Set1/Ash2 histone methyltransferase complex subunit ASH2
Pathway
ko04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K14964  ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K14964  ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    COMPASS/SET1 complex
     K14964  ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
    MLL-HCF complex
     K14964  ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
    MLL3/MLL4 complex
     K14964  ASH2; Set1/Ash2 histone methyltransferase complex subunit ASH2
Genes
HSA: 9070(ASH2L)
PTR: 464115(ASH2L)
PPS: 100991595(ASH2L)
GGO: 101126663(ASH2L)
PON: 100455544(ASH2L)
NLE: 100597221(ASH2L)
MCC: 699382(ASH2L)
MCF: 102133348(ASH2L)
CSAB: 103215637(ASH2L)
RRO: 104679666(ASH2L)
RBB: 108513582(ASH2L)
CJC: 100386808(ASH2L)
SBQ: 101029941(ASH2L)
MMU: 23808(Ash2l)
MCAL: 110299996(Ash2l)
MPAH: 110336212(Ash2l)
RNO: 290829(Ash2l)
MUN: 110540822(Ash2l)
CGE: 100771359(Ash2l)
NGI: 103745763(Ash2l) 103745772
HGL: 101709307(Ash2l)
CCAN: 109688943(Ash2l)
OCU: 100338600(ASH2L)
TUP: 102488704(ASH2L)
CFA: 475589(ASH2L)
VVP: 112916128(ASH2L)
AML: 100470005(ASH2L)
UMR: 103659122(ASH2L)
UAH: 113262098(ASH2L)
ORO: 101362095(ASH2L)
ELK: 111144497
FCA: 101088324(ASH2L)
PTG: 102951348(ASH2L)
PPAD: 109262308(ASH2L)
AJU: 106978383(ASH2L)
BTA: 100138350(ASH2L)
BOM: 102277921(ASH2L)
BIU: 109553477(ASH2L)
BBUB: 102411150(ASH2L)
CHX: 102186829(ASH2L)
OAS: 101111689(ASH2L)
SSC: 100627423(ASH2L)
CFR: 102517536(ASH2L)
CDK: 105089937(ASH2L)
BACU: 103014271(ASH2L)
LVE: 103075037(ASH2L)
OOR: 101277404(ASH2L)
DLE: 111173511(ASH2L)
PCAD: 102993767(ASH2L)
ECB: 100059465(ASH2L)
EPZ: 103540554(ASH2L)
EAI: 106824663(ASH2L)
MYB: 102249162(ASH2L)
MYD: 102763512(ASH2L)
MNA: 107535193(ASH2L)
HAI: 109393580(ASH2L)
DRO: 112306718(ASH2L)
PALE: 102881393(ASH2L)
RAY: 107515958(ASH2L)
MJV: 108409140(ASH2L)
LAV: 100665231(ASH2L)
TMU: 101348029
MDO: 100029781(ASH2L)
SHR: 100917906(ASH2L)
PCW: 110207587(ASH2L)
OAA: 100090368(ASH2L)
GGA: 426774(ASH2L)
MGP: 100546579(ASH2L)
CJO: 107323735(ASH2L)
NMEL: 110387050(ASH2L)
APLA: 101797934(ASH2L)
ACYG: 106044424(ASH2L)
TGU: 100222164(ASH2L)
LSR: 110473394(ASH2L)
SCAN: 103822698(ASH2L)
GFR: 102045658(ASH2L)
FAB: 101807665(ASH2L)
PHI: 102105269(ASH2L)
PMAJ: 107213852(ASH2L)
CCAE: 111938841(ASH2L)
CCW: 104694847(ASH2L)
ETL: 114066478(ASH2L)
FPG: 101919132(ASH2L)
FCH: 102055876(ASH2L)
CLV: 102083929(ASH2L)
EGZ: 104127849(ASH2L)
NNI: 104016014(ASH2L)
ACUN: 113488074(ASH2L)
PADL: 103912353(ASH2L)
AAM: 106496080(ASH2L)
ASN: 102383207(ASH2L)
AMJ: 102572553(ASH2L)
PSS: 102459345(ASH2L)
CMY: 102944579(ASH2L)
CPIC: 101935609(ASH2L)
ACS: 100554381(ash2l)
PVT: 110075173(ASH2L)
PBI: 103061967(ASH2L)
TSR: 106554412
PMUA: 114585347(ASH2L)
GJA: 107108167(ASH2L)
XLA: 100127317(ash2l.L) 108712672(ash2l.S)
XTR: 100492052(ash2l)
NPR: 108795412(ASH2L)
DRE: 558193(ash2l)
SRX: 107733292(ash2l) 107751890
SGH: 107549001(ash2l) 107568603
CCAR: 109082081 109093393(ash2l)
IPU: 108277215(ash2l)
PHYP: 113544920(ash2l)
AMEX: 103033518(ash2l)
EEE: 113584110(ash2l)
TRU: 101073289(ash2l)
LCO: 104934124(ash2l)
NCC: 104963370(ash2l)
MZE: 101468619(ash2l)
ONL: 100703050(ash2l)
OLA: 101168557(ash2l)
XMA: 102217364(ash2l)
XCO: 114150177(ash2l)
PRET: 103473194(ash2l)
CVG: 107102164(ash2l)
NFU: 107395663(ash2l)
KMR: 108245367(ash2l)
ALIM: 106532119(ash2l)
AOCE: 111574424(ash2l)
CSEM: 103389664(ash2l)
POV: 109626429(ash2l)
LCF: 108895486(ash2l)
SDU: 111239662(ash2l)
SLAL: 111659464(ash2l)
HCQ: 109525094(ash2l)
BPEC: 110166671(ash2l)
MALB: 109974762(ash2l)
ELS: 105015237(ash2l)
SFM: 108940332(ash2l)
PKI: 111861174(ash2l)
LCM: 102357711(ASH2L)
CMK: 103190312(ash2l)
RTP: 109931840(ash2l)
BFO: 118412063
CIN: 778945(ash2-like)
SPU: 584795
APLC: 110984817
DME: Dmel_CG6677(ash2)
DER: 6554708
DSE: 6607780
DSI: Dsimw501_GD21115(Dsim_GD21115)
DAN: 6500004
DSR: 110191161
DPE: 6595196
DMN: 108154791
DWI: 6647914
DAZ: 108617164
DNV: 108653520
DHE: 111593690
DVI: 6630339
MDE: 101895776
LCQ: 111676442
AME: 413573
BIM: 100740038
BTER: 100645379
CCAL: 108630460
OBB: 114876603
SOC: 105201347
MPHA: 105830715
AEC: 105147054
ACEP: 105625826
PBAR: 105425561
VEM: 105566036
HST: 105183425
DQU: 106745012
CFO: 105250679
LHU: 105673172
PGC: 109855014
OBO: 105286725
PCF: 106790235
NVI: 100122254
CSOL: 105362378
MDL: 103575150
TCA: 656910
DPA: 109540736
ATD: 109603140
NVL: 108561030
BMOR: 101746886
BMAN: 114253411
PMAC: 106720090
PRAP: 110996968
HAW: 110378020
TNL: 113500636
DNX: 107165832
AGS: 114127768
RMD: 113555178
BTAB: 109041959
CLEC: 106667141
ZNE: 110830398
FCD: 110849966
PVM: 113819197
TUT: 107371458
DPTE: 113793199
CSCU: 111612418
PTEP: 107449600
CEL: CELE_Y17G7B.2(ash-2)
CBR: CBG21026(Cbr-ash-2)
BMY: Bm1_16295
PCAN: 112575786
CRG: 105331718
MYI: 110450571
OBI: 106883251
LAK: 106154540
SHX: MS3_10930
EGL: EGR_01202
NVE: 116614573
EPA: 110231751
AMIL: 114948700
PDAM: 113666047
SPIS: 111337427
DGT: 114523085
HMG: 100207807
AQU: 100634607
ATH: AT1G51450(TRO)
ALY: 9330379
CRB: 17899927
BRP: 103871284
BOE: 106296371
RSZ: 108809359
THJ: 104817914
CPAP: 110811891
CIT: 102613335
TCC: 18589877
GRA: 105799387
GAB: 108456717
DZI: 111301159
VRA: 106756634
VAR: 108338791
VUN: 114169896
CCAJ: 109798528
CAM: 101504399
LJA: Lj3g3v3600530.1(Lj3g3v3600530.1) Lj3g3v3600530.2(Lj3g3v3600530.2)
ADU: 107477288
AIP: 107632469
FVE: 101315203
RCN: 112165198
PPER: 18780261
PMUM: 103326862
PAVI: 110753934
ZJU: 107412466
CSV: 101214790
CMO: 103492020
MCHA: 111021656
RCU: 8274316
JCU: 105648299
MESC: 110631141
QSU: 112018311
VVI: 100255238
SLY: 101243859
SPEN: 107002862
SOT: 102592430
CANN: 107847703
NSY: 104249073
NTO: 104104028
NAU: 109226647
INI: 109152433
SIND: 105170902
HAN: 110878395
LSV: 111899381
CCAV: 112520519
DCR: 108203039
BVG: 104890024
SOE: 110801214
DOSA: Os11t0145700-00(Os11g0145700) Os11t0146500-01(Os11g0146500) Os12t0143200-01(Os12g0143200)
ATS: 109741382(LOC109741382)
EGU: 105045576
MUS: 103993507
DCT: 110093645
PEQ: 110038093
AOF: 109848300
ATR: 18445931
VCN: VOLCADRAFT_107665(ASH2L)
MNG: MNEG_0868
APRO: F751_5651
DFA: DFA_05996
PCB: PCHAS_093370(PC000682.01.0)
TAN: TA04475
TPV: TP03_0423
BBO: BBOV_IV011530(23.m06312)
CPV: cgd1_740
SPAR: SPRG_06076
 » show all
Reference
  Authors
Wysocka J, Myers MP, Laherty CD, Eisenman RN, Herr W
  Title
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.
  Journal
Genes Dev 17:896-911 (2003)
DOI:10.1101/gad.252103
  Sequence
[hsa:9070]
Reference
  Authors
Cheng MK, Shearn A
  Title
The direct interaction between ASH2, a Drosophila trithorax group protein, and SKTL, a nuclear phosphatidylinositol 4-phosphate 5-kinase, implies a role for phosphatidylinositol 4,5-bisphosphate in maintaining transcriptionally active chromatin.
  Journal
Genetics 167:1213-23 (2004)
DOI:10.1534/genetics.103.018721
  Sequence
Reference
  Authors
Ikegawa S, Isomura M, Koshizuka Y, Nakamura Y
  Title
Cloning and characterization of ASH2L and Ash2l, human and mouse homologs of the Drosophila ash2 gene.
  Journal
Cytogenet Cell Genet 84:167-72 (1999)
DOI:10.1159/000015248
  Sequence
[hsa:9070]
LinkDB

KEGG   ORTHOLOGY: K14961
Entry
K14961                      KO                                     

Name
RBBP5, SWD1, CPS50
Definition
COMPASS component SWD1
Pathway
ko04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K14961  RBBP5, SWD1, CPS50; COMPASS component SWD1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K14961  RBBP5, SWD1, CPS50; COMPASS component SWD1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    COMPASS/SET1 complex
     K14961  RBBP5, SWD1, CPS50; COMPASS component SWD1
    COMPASS/SET1 complex (yeast)
     K14961  RBBP5, SWD1, CPS50; COMPASS component SWD1
    MLL-HCF complex
     K14961  RBBP5, SWD1, CPS50; COMPASS component SWD1
    MLL3/MLL4 complex
     K14961  RBBP5, SWD1, CPS50; COMPASS component SWD1
Genes
HSA: 5929(RBBP5)
PTR: 457665(RBBP5)
PPS: 100977836(RBBP5)
GGO: 101139973(RBBP5)
PON: 100173341(RBBP5)
NLE: 100597470(RBBP5)
MCC: 699057(RBBP5)
MCF: 102137661(RBBP5)
CSAB: 103230238(RBBP5)
RRO: 104664011(RBBP5)
RBB: 108535181(RBBP5)
CJC: 100404248(RBBP5)
SBQ: 101040515(RBBP5)
MMU: 213464(Rbbp5)
MCAL: 110298219(Rbbp5)
MPAH: 110321799(Rbbp5) 110336752
RNO: 304794(Rbbp5)
MUN: 110548251(Rbbp5)
CGE: 100754011(Rbbp5)
NGI: 103725958(Rbbp5)
HGL: 101713301(Rbbp5)
CCAN: 109699525(Rbbp5)
OCU: 100356995(RBBP5)
TUP: 102502448(RBBP5)
CFA: 488568(RBBP5)
VVP: 112914597(RBBP5)
AML: 100470847(RBBP5)
UMR: 103670980(RBBP5)
UAH: 113242494(RBBP5)
ORO: 101384563(RBBP5)
ELK: 111151058
FCA: 101084508(RBBP5)
PTG: 102969276(RBBP5)
PPAD: 109257194(RBBP5)
AJU: 106972908(RBBP5)
BTA: 510455(RBBP5)
BOM: 102271359(RBBP5) 102282073
BIU: 109570485(RBBP5)
BBUB: 102408109(RBBP5)
CHX: 102169037(RBBP5)
OAS: 101113868(RBBP5)
SSC: 100513301(RBBP5)
CFR: 102523404(RBBP5)
CDK: 105098639(RBBP5)
BACU: 103000552(RBBP5)
LVE: 103073848(RBBP5)
OOR: 101279508(RBBP5)
DLE: 111184778(RBBP5)
PCAD: 102992582(RBBP5)
ECB: 100054708(RBBP5)
EPZ: 103561208(RBBP5)
EAI: 106823587(RBBP5)
MYB: 102254870(RBBP5)
MYD: 102756331(RBBP5)
MNA: 107538731(RBBP5)
HAI: 109386502(RBBP5)
DRO: 112317999(RBBP5)
PALE: 102895616(RBBP5)
RAY: 107508587(RBBP5)
LAV: 100659816(RBBP5)
TMU: 101350636
MDO: 100013956(RBBP5)
SHR: 100931144(RBBP5)
PCW: 110219581(RBBP5)
OAA: 100076163(RBBP5)
GGA: 419826(RBBP5)
MGP: 100544888(RBBP5)
CJO: 107324706(RBBP5)
NMEL: 110388054(RBBP5)
APLA: 101800159(RBBP5)
ACYG: 106041309(RBBP5)
TGU: 100232275(RBBP5)
LSR: 110475008(RBBP5)
SCAN: 103825326
GFR: 102041594(RBBP5)
FAB: 101818618(RBBP5)
PHI: 102101916(RBBP5)
PMAJ: 107214771(RBBP5)
CCAE: 111939685(RBBP5)
CCW: 104692350(RBBP5)
ETL: 114071656(RBBP5)
FPG: 101914552(RBBP5)
FCH: 102048458(RBBP5)
CLV: 102088374(RBBP5)
EGZ: 104134067(RBBP5)
NNI: 104013133(RBBP5)
ACUN: 113488882(RBBP5)
PADL: 103919801(RBBP5)
AAM: 106490501(RBBP5)
ASN: 102378292(RBBP5)
AMJ: 102569964(RBBP5)
PSS: 102459516(RBBP5)
CMY: 102934348(RBBP5)
CPIC: 101950918(RBBP5)
ACS: 100566805(rbbp5)
PVT: 110080947(RBBP5)
PBI: 103053583(RBBP5)
PMUR: 107289108(RBBP5)
TSR: 106541860(RBBP5)
PMUA: 114599297(RBBP5)
GJA: 107117249(RBBP5)
XLA: 446510(rbbp5.S)
XTR: 595072(rbbp5)
NPR: 108799686(RBBP5)
DRE: 393215(rbbp5)
SANH: 107671568 107698287(rbbp5)
SGH: 107570668(rbbp5)
CCAR: 109064439(rbbp5) 109080063
IPU: 108255009(rbbp5)
AMEX: 103034189(rbbp5)
EEE: 113586970(rbbp5)
LCO: 104930692(rbbp5)
MZE: 101469538(rbbp5)
ONL: 100706391(rbbp5)
OLA: 101164873(rbbp5)
XMA: 102230869(rbbp5)
XCO: 114136028(rbbp5)
PRET: 103464638(rbbp5)
CVG: 107080720(rbbp5)
NFU: 107384813(rbbp5)
KMR: 108228266(rbbp5)
ALIM: 106522340(rbbp5)
AOCE: 111563158(rbbp5)
CSEM: 103386438(rbbp5)
POV: 109647353(rbbp5)
LCF: 108889797(rbbp5)
SDU: 111219384(rbbp5)
SLAL: 111662335(rbbp5)
HCQ: 109510280(rbbp5)
BPEC: 110174831(rbbp5)
MALB: 109966399(rbbp5)
OTW: 112244864(rbbp5)
ELS: 105016817(rbbp5)
SFM: 108923285(rbbp5)
PKI: 111834359(rbbp5)
LCM: 102364512(RBBP5)
CMK: 103182437(rbbp5)
RTP: 109918874(rbbp5)
BFO: 118417448
CIN: 100186009
SPU: 593381
APLC: 110983527
DME: Dmel_CG5585(Rbbp5)
DER: 6545232
DSE: 6616280
DSI: Dsimw501_GD12200(Dsim_GD12200)
DAN: 6506781
DSR: 110184616
DPE: 6595981
DMN: 108151624
DWI: 6638835
DAZ: 108614564
DNV: 108651682
DHE: 111605687
DVI: 6622529
MDE: 101900867
LCQ: 111679373
AAG: 5577229
AME: 410855
BIM: 100746759
BTER: 100647451
CCAL: 108627564
OBB: 114878544
SOC: 105204674
MPHA: 105838701
AEC: 105151953
ACEP: 105625018
PBAR: 105423568
VEM: 105565856
HST: 105181248
DQU: 106741921
CFO: 105250194
LHU: 105680139
PGC: 109854712
OBO: 105286375
PCF: 106786597
NVI: 100124260
CSOL: 105362212
MDL: 103573691
TCA: 658271
DPA: 109534383
NVL: 108568366
BMOR: 101740999
BMAN: 114248752
PMAC: 106715957
PRAP: 111003704
HAW: 110384432
TNL: 113497260
PXY: 105385198
API: 100165324
DNX: 107169530
RMD: 113548281
BTAB: 109035553
CLEC: 106672687
ZNE: 110833733
FCD: 110843605
PVM: 113811180
TUT: 107372272
DPTE: 113789254
CSCU: 111631010
PTEP: 107446308
CEL: CELE_F21H12.1(rbbp-5)
CBR: CBG02573
BMY: Bm1_24845
TSP: Tsp_08745
PCAN: 112567770
CRG: 105345017
MYI: 110464287
OBI: 106872501
SHX: MS3_03299
EGL: EGR_00423
NVE: 5515371
EPA: 110242028
ADF: 107345263
AMIL: 114953916
PDAM: 113686106
SPIS: 111338663
DGT: 114524876
HMG: 100203126
AQU: 100638554
ATH: AT3G21060(RBL)
CRB: 17893926
BRP: 103835503
BOE: 106314715
THJ: 104804661
CPAP: 110808599
CIT: 102620582
TCC: 18586896
GRA: 105783211
GAB: 108461280
EGR: 104454064
VAR: 108319599
LJA: Lj3g3v0807570.1(Lj3g3v0807570.1)
ADU: 107495182
AIP: 107605172
FVE: 101302219
RCN: 112173484
PPER: 18776303
PMUM: 103337023
PAVI: 110756463
PXB: 103933619
ZJU: 107413063
CSV: 101209834
CMO: 103489351
MCHA: 111018755
RCU: 8280770
JCU: 105635951
HBR: 110664023
JRE: 109017847
VVI: 100242780
SLY: 101252723
SPEN: 107004954
SOT: 102602044
CANN: 107839393
NSY: 104228889
NTO: 104103682
NAU: 109234019
INI: 109148377
SIND: 105172293
LSV: 111901049
CCAV: 112515131
DCR: 108204585
BVG: 104908686
SOE: 110774646
OSA: 4332006
DOSA: Os03t0207900-01(Os03g0207900)
OBR: 102714160
BDI: 100829872
ATS: 109763005(LOC109763005)
SBI: 8081855
ZMA: 100280497
MUS: 103979847
DCT: 110106036
PEQ: 110020423
AOF: 109837685
ATR: 18424650
PPP: 112289829
APRO: F751_3396
SCE: YAR003W(SWD1)
ERC: Ecym_6170
KMX: KLMA_10449(SWD1)
NCS: NCAS_0J01100(NCAS0J01100)
NDI: NDAI_0J01840(NDAI0J01840)
TPF: TPHA_0F00760(TPHA0F00760)
TBL: TBLA_0C03990(TBLA0C03990)
TDL: TDEL_0F02220(TDEL0F02220)
KAF: KAFR_0A06490(KAFR0A06490)
PIC: PICST_81347(SWD1)
CAL: CAALFM_C300690CA(SWD1)
SLB: AWJ20_1096(SWD1)
NCR: NCU02104
NTE: NEUTE1DRAFT51014(NEUTE1DRAFT_51014)
MGR: MGG_04651
SSCK: SPSK_05188
NHE: NECHADRAFT_75224(SWDA2101)
MAW: MAC_07407
MAJ: MAA_00660
CMT: CCM_05484
BFU: BCIN_05g01440(Bcswd1)
MBE: MBM_03517
ANI: AN0808.2
ANG: ANI_1_1722014(An01g12700)
ABE: ARB_00026
TVE: TRV_02752
PTE: PTT_15562
ZTR: MYCGRDRAFT_99872(SWDA2401)
SPO: SPAC23H3.05c(swd1)
CNE: CNC03150
CNB: CNBC4060
TASA: A1Q1_02764
LBC: LACBIDRAFT_303762(SWDA16201)
ABP: AGABI1DRAFT122989(AGABI1DRAFT_122989)
ABV: AGABI2DRAFT116704(AGABI2DRAFT_116704)
MGL: MGL_3013
MRT: MRET_3621
DDI: DDB_G0285847(rbbE)
DFA: DFA_00104(rbbE)
SPAR: SPRG_07694
 » show all
Reference
  Authors
Patel A, Dharmarajan V, Vought VE, Cosgrove MS
  Title
On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
  Journal
J Biol Chem 284:24242-56 (2009)
DOI:10.1074/jbc.M109.014498
  Sequence
[hsa:5929]
Reference
  Authors
Krogan NJ, Dover J, Khorrami S, Greenblatt JF, Schneider J, Johnston M, Shilatifard A
  Title
COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.
  Journal
J Biol Chem 277:10753-5 (2002)
DOI:10.1074/jbc.C200023200
  Sequence
[sce:YAR003W]
Reference
PMID:7558034
  Authors
Saijo M, Sakai Y, Kishino T, Niikawa N, Matsuura Y, Morino K, Tamai K, Taya Y
  Title
Molecular cloning of a human protein that binds to the retinoblastoma protein and chromosomal mapping.
  Journal
Genomics 27:511-9 (1995)
DOI:10.1006/geno.1995.1084
  Sequence
[hsa:5929]
LinkDB

KEGG   ORTHOLOGY: K14963
Entry
K14963                      KO                                     

Name
WDR5, SWD3, CPS30
Definition
COMPASS component SWD3
Pathway
ko04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HAT complexes
    ATAC complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
    NSL complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
   HMT complexes
    COMPASS/SET1 complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
    COMPASS/SET1 complex (yeast)
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
    MLL-HCF complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
    MLL3/MLL4 complex
     K14963  WDR5, SWD3, CPS30; COMPASS component SWD3
Genes
HSA: 11091(WDR5) 54554(WDR5B)
PTR: 460630(WDR5B) 746901(WDR5)
PPS: 100988935(WDR5) 103782718(WDR5B)
GGO: 101128389(WDR5) 101143690(WDR5B)
PON: 100174268(WDR5B) 100937108(WDR5)
NLE: 100583558(WDR5) 100605376(WDR5B)
MCC: 714703(WDR5B) 722123(WDR5)
MCF: 102133326(WDR5) 102142817(WDR5B)
CSAB: 103228188(WDR5B) 103239670(WDR5)
RRO: 104667922(WDR5B) 104669711(WDR5)
RBB: 108513196(WDR5) 108519294(WDR5B)
CJC: 100404600(WDR5B) 100407139(WDR5)
SBQ: 101044805(WDR5) 101046172(WDR5B)
MMU: 140858(Wdr5) 69544(Wdr5b)
MCAL: 110289684(Wdr5) 110311569(Wdr5b)
MPAH: 110318087(Wdr5) 110329721(Wdr5b)
RNO: 303907(Wdr5b) 362093(Wdr5)
MUN: 110547225(Wdr5b) 110548924(Wdr5)
CGE: 100767658(Wdr5b) 100768958(Wdr5)
NGI: 103741975(Wdr5b) 103742822(Wdr5)
HGL: 101696645(Wdr5b) 101723351(Wdr5)
CCAN: 109689244(Wdr5b) 109695048(Wdr5)
OCU: 100358109(WDR5B)
TUP: 102475039(WDR5B) 102501799(WDR5)
CFA: 100685660(WDR5B) 608113(WDR5)
VVP: 112913493(WDR5B) 112935884(WDR5)
AML: 100477065(WDR5) 100484804(WDR5B)
UMR: 103678761(WDR5B) 103679925(WDR5)
UAH: 113252248(WDR5B) 113266583(WDR5)
ORO: 101364832(WDR5) 101384276(WDR5B)
FCA: 101082447(WDR5) 101086592(WDR5B)
PTG: 102952912(WDR5B) 102957253(WDR5)
PPAD: 109258265(WDR5) 109266477(WDR5B)
AJU: 106984103(WDR5B) 106988270(WDR5)
BTA: 100125836(WDR5) 100138335(WDR5B)
BOM: 102264764(WDR5) 102273992(WDR5B)
BIU: 109555088(WDR5B)
BBUB: 102405727(WDR5B) 102405857(WDR5)
CHX: 102177810(WDR5) 102186906(WDR5B)
OAS: 101113552(WDR5B) 101118597(WDR5)
SSC: 100156729(WDR5) 100627452(WDR5B)
CFR: 102509213(WDR5) 102520548(WDR5B)
CDK: 105090294(WDR5B) 105102806(WDR5)
BACU: 103002089(WDR5B) 103004110(WDR5)
LVE: 103071811(WDR5B) 103083572(WDR5)
OOR: 101269329(WDR5B) 101270353(WDR5)
DLE: 111171472(WDR5B) 111177067(WDR5)
PCAD: 102991102(WDR5) 102991509(WDR5B)
ECB: 100069126(WDR5) 100070656(WDR5B)
EPZ: 103548429(WDR5B) 103561602(WDR5)
EAI: 106823723(WDR5B) 106845344(WDR5)
MYB: 102258638(WDR5B) 102259721(WDR5)
MYD: 102762509(WDR5) 102767541(WDR5B)
MNA: 107524615(WDR5) 107527400(WDR5B)
HAI: 109381213(WDR5) 109388223(WDR5B)
DRO: 112306429(WDR5) 112320639(WDR5B)
PALE: 102881828(WDR5) 102887720(WDR5B)
RAY: 107502029(WDR5) 107512488(WDR5B)
MJV: 108399549(WDR5) 108407467(WDR5B)
LAV: 100671380(WDR5B) 100673925(WDR5)
SHR: 100921909(WDR5) 100930938
PCW: 110205366(WDR5)
OAA: 100074270(WDR5)
GGA: 417144(WDR5)
MGP: 100541376(WDR5)
CJO: 107321859(WDR5)
NMEL: 110406798(WDR5)
APLA: 101797619(WDR5)
ACYG: 106044131(WDR5)
TGU: 100227253(WDR5)
LSR: 110477628(WDR5)
SCAN: 103818961(WDR5)
GFR: 102037774(WDR5)
FAB: 101812189(WDR5)
PHI: 102100079(WDR5)
PMAJ: 107211986(WDR5)
CCAE: 111937050(WDR5)
CCW: 104688343(WDR5)
ETL: 114059119(WDR5)
FPG: 101923680(WDR5)
FCH: 102048034(WDR5)
CLV: 102098320(WDR5)
EGZ: 104129338(WDR5)
NNI: 104023199(WDR5)
ACUN: 113486537(WDR5)
PADL: 103915262(WDR5)
AAM: 106486992(WDR5)
ASN: 102384300(WDR5)
AMJ: 102557893(WDR5)
PSS: 102443711(WDR5)
CMY: 102935004(WDR5)
CPIC: 101935819(WDR5)
ACS: 100566644(wdr5) 103280676(wdr88)
PVT: 110089297(WDR5)
PBI: 103047991(WDR5)
PMUR: 107291027(WDR5)
TSR: 106548360(WDR5) 106550562(WDR88)
PMUA: 114589250(WDR5)
GJA: 107106566(WDR5)
XLA: 446809(wdr5.L) 447447(wdr5.S)
XTR: 496891(wdr5)
NPR: 108795635(WDR5)
DRE: 406372(wdr5)
CCAR: 109078979 109098293(wdr5)
IPU: 108278780(wdr5)
PHYP: 113535582(wdr5)
AMEX: 103023146 103033424(wdr5)
EEE: 113573076 113573682(wdr5)
TRU: 101079208(wdr5)
LCO: 104924863(wdr5)
MZE: 101467125(wdr5)
ONL: 100690256(wdr5)
OLA: 101166483(wdr5)
XMA: 102234605(wdr5)
XCO: 114149502(wdr5)
PRET: 103474008(wdr5)
CVG: 107102159(wdr5)
NFU: 107396361(wdr5)
KMR: 108241381(wdr5)
ALIM: 106513572(wdr5)
AOCE: 111563718(wdr5)
CSEM: 103389491(wdr5) 103397940
POV: 109643566(wdr5)
LCF: 108880297(wdr5) 108894557
SDU: 111237447 111237506(wdr5)
SLAL: 111649058 111655952(wdr5)
HCQ: 109530340(wdr5)
BPEC: 110172341(wdr5)
MALB: 109957409 109960757(wdr5)
ELS: 105024177(wdr5)
SFM: 108927192 108938379(wdr5)
LCM: 102363163(WDR5)
CMK: 103182966(wdr5)
RTP: 109926241
BFO: 118421231
CIN: 100176938
SPU: 579376
APLC: 110988617
SKO: 100375790
DME: Dmel_CG10931(CG10931) Dmel_CG17437(wds)
DSI: Dsimw501_GD11312(Dsim_GD11312) Dsimw501_GD16610(Dsim_GD16610)
DAN: 6504881
DVI: 6633369
MDE: 101900923
LCQ: 111679275
AAG: 5580266
AME: 552669
BIM: 100742659
BTER: 100642280
CCAL: 108625612
OBB: 114877620
SOC: 105207713
MPHA: 105838145
AEC: 105148427
ACEP: 105619088
PBAR: 105433387
VEM: 105570420
HST: 105182660
DQU: 106744095
CFO: 105258800
LHU: 105673266
PGC: 109854748
OBO: 105280398
PCF: 106788391
NVI: 100114928
CSOL: 105360713
TCA: 660221
DPA: 109542708
NVL: 108562345
BMOR: 692642(Wds)
BMAN: 114245527
PMAC: 106719638
PRAP: 111004391
HAW: 110374459
TNL: 113494496
PXY: 105398547
DNX: 107169774
AGS: 114125296
RMD: 113552203
BTAB: 109040787
CLEC: 106661058
ZNE: 110835223
FCD: 110848000
TUT: 107362251
DPTE: 113791897
PTEP: 107455599
CEL: CELE_C14B1.4(wdr-5.1) CELE_K04G11.4(wdr-5.2) CELE_ZC302.2(wdr-5.3)
CBR: CBG08899 CBG09206(Cbr-tag-125) CBG09688
BMY: Bm1_28000
OBI: 106875273
LAK: 106154500
SHX: MS3_02750
EGL: EGR_07002
ATH: AT3G49660(WDR5a) AT4G02730(WDR5b)
LJA: Lj4g3v2352060.1(Lj4g3v2352060.1) Lj5g3v0977410.1(Lj5g3v0977410.1)
DOSA: Os03t0725400-01(Os03g0725400) Os07t0572000-01(Os07g0572000)
ATS: 109737680(LOC109737680) 109752048(LOC109752048) 109777321(LOC109777321) 109777636(LOC109777636)
ZMA: 100216826(pco089076) 100276374 103633326
VCN: VOLCADRAFT_109001(VMUT11)
APRO: F751_0490
SCE: YBR175W(SWD3)
ERC: Ecym_7078
KMX: KLMA_10808(SWD3)
NCS: NCAS_0B01910(NCAS0B01910)
NDI: NDAI_0C05770(NDAI0C05770)
TPF: TPHA_0I01690(TPHA0I01690)
TBL: TBLA_0B04390(TBLA0B04390)
TDL: TDEL_0A05290(TDEL0A05290)
KAF: KAFR_0I00640(KAFR0I00640)
PIC: PICST_32006(SWD3)
CAL: CAALFM_C602170CA(SWD3)
SLB: AWJ20_5017(SWD3)
NCR: NCU03244
NTE: NEUTE1DRAFT72317(NEUTE1DRAFT_72317)
MGR: MGG_04473
SSCK: SPSK_02354
NHE: NECHADRAFT_122274(SWDC2101)
MAW: MAC_03191
MAJ: MAA_04285
CMT: CCM_02300
MBE: MBM_01293
ANI: AN3926.2
ANG: ANI_1_1672094(An11g01650)
ABE: ARB_07942
TVE: TRV_04096
PTE: PTT_04320
ZTR: MYCGRDRAFT_100547(SWDC2401)
SPO: SPBC354.03(swd3)
CNE: CND01430
CNB: CNBD4890
TASA: A1Q1_03324
ABP: AGABI1DRAFT119061(AGABI1DRAFT_119061) AGABI1DRAFT32084(AGABI1DRAFT_32084)
ABV: AGABI2DRAFT115290(AGABI2DRAFT_115290) AGABI2DRAFT186220(AGABI2DRAFT_186220) AGABI2DRAFT62628(AGABI2DRAFT_62628)
DDI: DDB_G0287273(wdr5)
EHI: EHI_117620(157.t00011)
CPV: cgd2_2880
SMIN: v1.2.001462.t1(symbB.v1.2.001462.t1)
CALH: IJ00_02690
FTJ: FTUN_0953
 » show all
Reference
  Authors
Patel A, Dharmarajan V, Vought VE, Cosgrove MS
  Title
On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
  Journal
J Biol Chem 284:24242-56 (2009)
DOI:10.1074/jbc.M109.014498
  Sequence
[hsa:11091]
Reference
  Authors
Krogan NJ, Dover J, Khorrami S, Greenblatt JF, Schneider J, Johnston M, Shilatifard A
  Title
COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.
  Journal
J Biol Chem 277:10753-5 (2002)
DOI:10.1074/jbc.C200023200
  Sequence
[sce:YBR175W]
Reference
  Authors
Gori F, Divieti P, Demay MB
  Title
Cloning and characterization of a novel WD-40 repeat protein that dramatically accelerates osteoblastic differentiation.
  Journal
J Biol Chem 276:46515-22 (2001)
DOI:10.1074/jbc.M105757200
  Sequence
[hsa:11091]
LinkDB

KEGG   ORTHOLOGY: K09186
Entry
K09186                      KO                                     

Name
MLL1
Definition
[histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
Pathway
ko00310  Lysine degradation
ko01100  Metabolic pathways
ko04934  Cushing syndrome
ko05202  Transcriptional misregulation in cancer
Disease
H00001  B-cell acute lymphoblastic leukemia
H00002  T-cell acute lymphoblastic leukemia
H01879  Wiedemann-Steiner syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    K09186  MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K09186  MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K09186  MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09186  MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1
   03036 Chromosome and associated proteins
    K09186  MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     K09186  MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1
Transcription factors [BR:ko03000]
 Eukaryotic type
  Zinc finger
   CXXC CpG-binding proteins
    K09186  MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K09186  MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1
   HMT complexes
    MLL-HCF complex
     K09186  MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1
Other DBs
RN: R03875 R04866 R04867
GO: 0042800
Genes
HSA: 4297(KMT2A)
PTR: 451587(KMT2A)
PPS: 100984332(KMT2A)
GGO: 101129366(KMT2A)
PON: 100441102(KMT2A)
NLE: 100604245(KMT2A)
MCC: 705511(KMT2A)
CSAB: 103248594(KMT2A)
RRO: 104665589(KMT2A)
RBB: 108536375(KMT2A)
CJC: 100391138(KMT2A)
SBQ: 101029847(KMT2A)
MMU: 214162(Kmt2a)
MCAL: 110301786(Kmt2a)
MPAH: 110327485(Kmt2a)
RNO: 315606(Kmt2a)
MUN: 110549115(Kmt2a)
CGE: 100760424(Kmt2a)
NGI: 103748298(Kmt2a)
HGL: 101716671(Kmt2a)
CCAN: 109689973(Kmt2a)
OCU: 100353733(KMT2A)
TUP: 102473382(KMT2A)
CFA: 479417(KMT2A)
VVP: 112920160(KMT2A)
AML: 100484220(KMT2A)
UMR: 103662507(KMT2A)
UAH: 113259992(KMT2A)
ORO: 101363669(KMT2A)
ELK: 111153928
FCA: 101090288(KMT2A)
PTG: 102956940(KMT2A)
PPAD: 109278556(KMT2A)
AJU: 106966460(KMT2A)
BTA: 508330(KMT2A)
BOM: 102280025(KMT2A)
BIU: 109569413(KMT2A)
BBUB: 102401126(KMT2A)
CHX: 102169033(KMT2A)
OAS: 101101916(KMT2A)
SSC: 100623006(KMT2A)
CFR: 102517824(KMT2A)
CDK: 105090168(KMT2A)
BACU: 103014183(KMT2A)
LVE: 103068531(KMT2A)
OOR: 101278571(KMT2A)
DLE: 111166868(KMT2A)
ECB: 100071238(KMT2A)
EPZ: 103546689(KMT2A)
EAI: 106840333(KMT2A)
HAI: 109385301(KMT2A)
DRO: 112314381(KMT2A)
RAY: 107502258(KMT2A)
MJV: 108384991(KMT2A)
LAV: 100653681(KMT2A)
TMU: 101351964
MDO: 100031440(KMT2A)
SHR: 100924557(KMT2A)
PCW: 110207193(KMT2A)
OAA: 100086068(KMT2A)
GGA: 414897(KMT2A)
MGP: 100540662(KMT2A)
CJO: 107324133(KMT2A)
NMEL: 110387546(KMT2A)
APLA: 101797321(KMT2A)
ACYG: 106039772(KMT2A)
TGU: 100231049(KMT2A)
LSR: 110470458(KMT2A)
SCAN: 103822784(KMT2A)
GFR: 102036439(KMT2A)
FAB: 101813917(KMT2A)
PHI: 102103515(KMT2A)
PMAJ: 107214385(KMT2A)
CCAE: 111939213(KMT2A)
CCW: 104692048(KMT2A)
ETL: 114056306(KMT2A)
FPG: 101922729(KMT2A)
FCH: 102059401(KMT2A)
CLV: 102084453(KMT2A)
EGZ: 104135361(KMT2A)
NNI: 104016208(KMT2A)
ACUN: 113488577(KMT2A)
PADL: 103916551(KMT2A)
AAM: 106485191(KMT2A)
ASN: 102385246(KMT2A)
AMJ: 102572253(KMT2A)
PSS: 102463628(KMT2A)
CMY: 102941272(KMT2A)
CPIC: 101941687(KMT2A)
ACS: 100560745(kmt2a)
XTR: 100135006(kmt2a)
DRE: 557048(kmt2a)
CCAR: 109103211
IPU: 108277661(kmt2a)
PHYP: 113533005(kmt2a)
AMEX: 103035686
EEE: 113579441(kmt2a)
TRU: 101079297(kmt2a)
LCO: 104936774(kmt2a)
MZE: 101478918(kmt2a)
ONL: 100700211(kmt2a)
OLA: 101171020(kmt2a)
XMA: 102233842(kmt2a)
XCO: 114133379(kmt2a)
PRET: 103474566(kmt2a)
CVG: 107088316(kmt2a)
NFU: 107380358(kmt2a)
KMR: 108246035(kmt2a)
ALIM: 106533989(kmt2a)
AOCE: 111584353
CSEM: 103378141(kmt2a)
POV: 109630237(kmt2a)
LCF: 108886384(kmt2a)
SDU: 111228034(kmt2a)
SLAL: 111650938(kmt2a)
HCQ: 109529394(kmt2a)
BPEC: 110154093(kmt2a)
MALB: 109960262(kmt2a)
SASA: 106612477(kmt2a)
ELS: 105011706(kmt2a)
SFM: 108936191(kmt2a)
PKI: 111846253(kmt2a)
CIN: 100180972
SPU: 579728
DME: Dmel_CG8651(trx)
DSI: Dsimw501_GD20433(Dsim_GD20433)
DPE: 6587342
DMN: 108155493
DAZ: 108621479
DNV: 115563744
DHE: 111593273
AAG: 5573555
AALB: 109416761
AME: 408716
BIM: 100748492
BTER: 100646252
CCAL: 108625224
TCA: 658843(trithorax)
 » show all
Reference
  Authors
Avdic V, Zhang P, Lanouette S, Groulx A, Tremblay V, Brunzelle J, Couture JF
  Title
Structural and biochemical insights into MLL1 core complex assembly.
  Journal
Structure 19:101-8 (2011)
DOI:10.1016/j.str.2010.09.022
  Sequence
[hsa:4297]
Reference
  Authors
Ansari KI, Mandal SS
  Title
Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing.
  Journal
FEBS J 277:1790-804 (2010)
DOI:10.1111/j.1742-4658.2010.07606.x
Reference
PMID:8703835
  Authors
Nilson I, Lochner K, Siegler G, Greil J, Beck JD, Fey GH, Marschalek R
  Title
Exon/intron structure of the human ALL-1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias.
  Journal
Br J Haematol 93:966-72 (1996)
DOI:10.1046/j.1365-2141.1996.d01-1748.x
  Sequence
[hsa:4297]
LinkDB

KEGG   ORTHOLOGY: K09187
Entry
K09187                      KO                                     

Name
MLL2, ALR
Definition
[histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
Pathway
ko00310  Lysine degradation
ko01100  Metabolic pathways
ko04934  Cushing syndrome
Disease
H00570  Kabuki syndrome
H01613  Follicular lymphoma
H02434  Diffuse large B-cell lymphoma, not otherwise specified
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    K09187  MLL2, ALR; [histone H3]-lysine4 N-trimethyltransferase MLL2
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K09187  MLL2, ALR; [histone H3]-lysine4 N-trimethyltransferase MLL2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K09187  MLL2, ALR; [histone H3]-lysine4 N-trimethyltransferase MLL2
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.354  [histone H3]-lysine4 N-trimethyltransferase
     K09187  MLL2, ALR; [histone H3]-lysine4 N-trimethyltransferase MLL2
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K09187  MLL2, ALR; [histone H3]-lysine4 N-trimethyltransferase MLL2
   HMT complexes
    MLL-HCF complex
     K09187  MLL2, ALR; [histone H3]-lysine4 N-trimethyltransferase MLL2
Other DBs
RN: R03875 R04866 R04867
GO: 0042800
Genes
HSA: 8085(KMT2D)
PTR: 100610362(KMT2D)
PPS: 100995808(KMT2D)
GGO: 101144774(KMT2D)
PON: 100441715(KMT2D)
NLE: 100586637(KMT2D)
MCC: 710795(KMT2D)
MCF: 102123773(KMT2D)
CSAB: 103238253(KMT2D)
RRO: 104679726(KMT2D)
RBB: 108543918(KMT2D)
CJC: 100408425(KMT2D)
SBQ: 101037539(KMT2D)
MMU: 381022(Kmt2d)
MCAL: 110310214(Kmt2d)
MPAH: 110334561(Kmt2d)
RNO: 100362634(Kmt2d)
MUN: 110547438(Kmt2d)
CGE: 100765465(Kmt2d)
NGI: 103750570(Kmt2d)
HGL: 101718411(Kmt2d)
CCAN: 109694824(Kmt2d)
OCU: 100357052(KMT2D)
TUP: 102480722(KMT2D)
CFA: 486558(KMT2D)
VVP: 112921101(KMT2D)
AML: 100479447(KMT2D)
UMR: 103675622(KMT2D)
UAH: 113257661(KMT2D)
ORO: 101369213(KMT2D)
ELK: 111157787
FCA: 101095268(KMT2D)
PTG: 102962859(KMT2D)
PPAD: 109249058(KMT2D)
AJU: 106969329(KMT2D)
BTA: 506805(KMT2D)
BOM: 102268887(KMT2D)
BIU: 109559148(KMT2D)
BBUB: 102401706(KMT2D)
CHX: 102168698(KMT2D)
OAS: 101120741(KMT2D)
SSC: 110260656(KMT2D)
CFR: 102515223(KMT2D)
CDK: 105103813(KMT2D)
BACU: 103004413(KMT2D)
LVE: 103082116(KMT2D)
OOR: 101269640(KMT2D)
DLE: 111174034(KMT2D)
PCAD: 102981848(KMT2D)
ECB: 100058932(KMT2D)
EPZ: 103552202(KMT2D)
EAI: 106836860(KMT2D)
MYB: 102244965(KMT2D)
MYD: 102762410(KMT2D)
MNA: 107528109(KMT2D)
HAI: 109393224(KMT2D)
DRO: 112318232(KMT2D)
PALE: 102888593(KMT2D)
RAY: 107514237(KMT2D)
MJV: 108383409(KMT2D)
LAV: 100670013(KMT2D)
TMU: 101353099
MDO: 103099827(KMT2D)
SHR: 100928575(KMT2D)
PCW: 110194047(KMT2D)
GGA: 425846(KMT2D)
MGP: 104915798
CJO: 107325738(KMT2D)
NMEL: 110389135(KMT2D)
TGU: 100226907(KMT2D)
LSR: 110480395(KMT2D)
SCAN: 103824625(KMT2D)
FAB: 101818086(KMT2D)
PHI: 102100454(KMT2D)
PMAJ: 107198594(KMT2D)
ASN: 102373099(KMT2D)
CPIC: 101934288(KMT2D)
ACS: 100554175(kmt2d)
PVT: 110075080(KMT2D)
PMUA: 114587663
GJA: 107105838(KMT2D)
XTR: 100494109(kmt2d)
NPR: 108791395(KMT2D)
DRE: 100536523(kmt2d)
SRX: 107708781(kmt2d) 107716211
SGH: 107563643 107570495(kmt2d)
IPU: 108275851
PHYP: 113530648(kmt2d)
AMEX: 103042576(kmt2d)
EEE: 113584431(kmt2d)
TRU: 101062458(kmt2d)
LCO: 104932523(kmt2d)
NCC: 104956939(kmt2d)
MZE: 101486529(kmt2d)
ONL: 100706752(kmt2d)
OLA: 101172242(kmt2d)
XMA: 102237866(kmt2d)
XCO: 114140852(kmt2d)
PRET: 103467355(kmt2d)
CVG: 107086766(kmt2d)
NFU: 107390885(kmt2d)
KMR: 108235223(kmt2d)
ALIM: 106524867(kmt2d)
AOCE: 111577439(kmt2d)
CSEM: 103385102(kmt2d)
POV: 109630747(kmt2d)
LCF: 108876442(kmt2d)
SDU: 111219023(kmt2d)
SLAL: 111668971(kmt2d)
HCQ: 109531346(kmt2d)
BPEC: 110164958(kmt2d)
MALB: 109968659(kmt2d)
SASA: 106567046(kmt2d) 106572669
OTW: 112221704(kmt2d) 112247360
ELS: 105013562(kmt2d)
SFM: 108939256
PKI: 111860624
LCM: 102354014(KMT2D)
 » show all
Reference
  Authors
Andreu-Vieyra CV, Chen R, Agno JE, Glaser S, Anastassiadis K, Stewart AF, Matzuk MM
  Title
MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.
  Journal
PLoS Biol 8:e1000453 (2010)
DOI:10.1371/journal.pbio.1000453
  Sequence
[hsa:8085] [mmu:381022]
Reference
  Authors
Ansari KI, Mandal SS
  Title
Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing.
  Journal
FEBS J 277:1790-804 (2010)
DOI:10.1111/j.1742-4658.2010.07606.x
Reference
PMID:9247308
  Authors
Prasad R, Zhadanov AB, Sedkov Y, Bullrich F, Druck T, Rallapalli R, Yano T, Alder H, Croce CM, Huebner K, Mazo A, Canaani E
  Title
Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax.
  Journal
Oncogene 15:549-60 (1997)
DOI:10.1038/sj.onc.1201211
  Sequence
[hsa:8085]
LinkDB

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