KEGG   ORTHOLOGY: K15293
Entry
K15293                      KO                                     

Name
UNC13A_B_C, MUNC13
Definition
protein unc-13 A/B/C
Pathway
map04721  Synaptic vesicle cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09156 Nervous system
   04721 Synaptic vesicle cycle
    K15293  UNC13A_B_C, MUNC13; protein unc-13 A/B/C
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K15293  UNC13A_B_C, MUNC13; protein unc-13 A/B/C
Membrane trafficking [BR:ko04131]
 SNARE
  SNARE associated proteins
   Syntaxin-binding proteins
    K15293  UNC13A_B_C, MUNC13; protein unc-13 A/B/C
Genes
HSA: 10497(UNC13B) 23025(UNC13A) 440279(UNC13C)
PTR: 453453(UNC13C) 455844(UNC13A) 464150(UNC13B)
PPS: 100973070(UNC13A) 100983391(UNC13B) 100993672(UNC13C)
GGO: 101142045(UNC13B) 101151166(UNC13C) 101151197(UNC13A)
PON: 100172629(UNC13B) 100451530(UNC13C) 100461446(UNC13A)
NLE: 100593085(UNC13B) 100596083(UNC13C) 100602347(UNC13A)
MCC: 697368(UNC13C) 697393(UNC13B) 720000(UNC13A)
MCF: 101866166(UNC13C) 102115169(UNC13B) 102123626(UNC13A)
CSAB: 103219228(UNC13B) 103234148(UNC13A) 103245596(UNC13C)
CATY: 105598148(UNC13B) 105601128(UNC13C) 105601675(UNC13A)
PANU: 100997179(UNC13B) 101003139(UNC13A)
RRO: 104653799(UNC13C) 104660964(UNC13A) 104680034(UNC13B)
RBB: 108524483(UNC13B) 108534281(UNC13A) 108542601 108542752
TFN: 117070625(UNC13C) 117076465(UNC13A) 117099019(UNC13B)
PTEH: 111536772(UNC13B) 111552797(UNC13C) 111554241(UNC13A)
CJC: 100397539(UNC13C) 100405414(UNC13B) 100411765(UNC13A)
SBQ: 101031450(UNC13A) 101044601(UNC13B) 101051957(UNC13C)
MMUR: 105854992(UNC13A) 105874312(UNC13B) 105881425(UNC13C)
MMU: 208898(Unc13c) 22249(Unc13b) 382018(Unc13a)
MCAL: 110292216(Unc13b) 110299674(Unc13a) 110301288(Unc13c)
MPAH: 110327527(Unc13c) 110337002(Unc13a) 110338617(Unc13b)
RNO: 286931(Unc13c) 64829(Unc13a) 64830(Unc13b)
MCOC: 116069526(Unc13a) 116072609(Unc13c) 116095885(Unc13b)
MUN: 110547125(Unc13b) 110549132 110549195(Unc13a) 110564510
CGE: 100754632(Unc13c) 100773787(Unc13a) 100774681(Unc13b)
PLEU: 114687947(Unc13a) 114690444(Unc13c) 114703217(Unc13b)
NGI: 103726893(Unc13a) 103731415(Unc13c) 103741550(Unc13b)
HGL: 101710593(Unc13a) 101717680(Unc13b) 101722108(Unc13c)
CCAN: 109674706 109674723 109685312(Unc13b) 109698334(Unc13a)
OCU: 100345810(UNC13B) 100352093(UNC13C)
TUP: 102479230(UNC13B) 102484282(UNC13A) 102487672(UNC13C)
CFA: 100683511(UNC13B) 484833(UNC13A) 487564(UNC13C)
VVP: 112913175(UNC13A) 112917048(UNC13C) 112930856(UNC13B)
VLG: 121485427(UNC13C) 121494156(UNC13A) 121494471(UNC13B)
AML: 100472307(UNC13B) 100473240(UNC13A) 100473303(UNC13C)
UMR: 103667115(UNC13B) 103675172(UNC13A) 103676767(UNC13C)
UAH: 113256599(UNC13A) 113260485(UNC13B) 113269643(UNC13C)
ORO: 101364807(UNC13C) 101372298(UNC13A) 101379557(UNC13B)
ELK: 111144141 111145919 111153260
MPUF: 101670588(UNC13B) 101672448(UNC13C) 101691440(UNC13A)
EJU: 114196461(UNC13A) 114206459(UNC13C) 114218239(UNC13B)
MLX: 118003149(UNC13C) 118004967(UNC13A) 118017980(UNC13B)
FCA: 101087486(UNC13C) 101089655(UNC13B) 101091602(UNC13A)
PTG: 102957742(UNC13B) 102965122(UNC13A) 102969661(UNC13C)
PPAD: 109247959(UNC13A) 109262960(UNC13C) 109270180(UNC13B)
AJU: 106969159(UNC13A) 106981229(UNC13B) 106989033(UNC13C)
HHV: 120221294(UNC13B) 120239204(UNC13A) 120246597(UNC13C)
BTA: 100337128(UNC13C) 526874(UNC13A) 530692(UNC13B)
BOM: 102273158(UNC13B) 102285437(UNC13A) 102285566 102286324(UNC13C)
BIU: 109560824(UNC13A) 109563000(UNC13B) 109565111(UNC13C)
BBUB: 102388992(UNC13A) 102412475(UNC13C) 102415278(UNC13B)
CHX: 102172616(UNC13A) 102176042(UNC13B) 102189961(UNC13C)
OAS: 101113588(UNC13A) 101117731(UNC13B) 101123470(UNC13C)
ODA: 120853011(UNC13C) 120864202(UNC13A) 120878442(UNC13B)
SSC: 100516123(UNC13C) 100621404(UNC13B) 100627038(UNC13A)
CFR: 102504108 102511994(UNC13A) 102515705(UNC13C)
CDK: 105088679(UNC13C) 105101853(UNC13A) 105102307(UNC13B) 116152678
BACU: 103004386(UNC13C) 103013800(UNC13A) 103019218(UNC13B)
LVE: 103068548(UNC13C) 103078014 103081150(UNC13A) 103082589(UNC13B)
OOR: 101284941(UNC13A) 101290145(UNC13C) 101290381(UNC13B)
DLE: 111166647(UNC13A) 111177634(UNC13C) 111187954(UNC13B)
PCAD: 102980081(UNC13B) 102986290(UNC13C) 102988188(UNC13A)
ECB: 100054917(UNC13C) 100055666(UNC13B) 100146356(UNC13A)
EPZ: 103541482(UNC13A) 103554398 103556377(UNC13C) 103566719(UNC13B)
EAI: 106830823(UNC13A) 106837151(UNC13C) 106846991(UNC13B)
MYB: 102246928(UNC13B) 102254367(UNC13C) 102255200(UNC13A)
MYD: 102766041(UNC13B) 102768558(UNC13A) 102769108(UNC13C)
MMYO: 118652117(UNC13C) 118659050(UNC13A) 118667351(UNC13B)
MNA: 107534289(UNC13A) 107544962(UNC13B) 107546465(UNC13C)
HAI: 109382396(UNC13A) 109393766(UNC13B) 109394243(UNC13C)
DRO: 112304542(UNC13B) 112305141(UNC13A) 112311351(UNC13C)
SHON: 118975078(UNC13A) 118979803(UNC13B) 118992235(UNC13C)
AJM: 119046813(UNC13A) 119048727 119065530(UNC13C)
MMF: 118616098(UNC13A) 118629420(UNC13B) 118631562(UNC13C)
PALE: 102879862(UNC13C) 102888671(UNC13B) 102897623(UNC13A)
RAY: 107502766(UNC13B) 107515167(UNC13C) 107517237(UNC13A)
MJV: 108383447 108388009(UNC13A) 108391731(UNC13B)
TOD: 119232552(UNC13B) 119238643(UNC13C) 119241105(UNC13A)
LAV: 100662227(UNC13C) 100669085(UNC13B) 100674161(UNC13A)
TMU: 101343860 101352304 101354912
MDO: 100031506(UNC13C) 100618160(UNC13B) 100619916(UNC13A) 107652056
SHR: 100915455(UNC13C) 100918963 100920361(UNC13A)
PCW: 110196238(UNC13A) 110201436(UNC13B) 110204930(UNC13C)
OAA: 100076365(UNC13A) 100085315(UNC13C) 103166756(UNC13B)
GGA: 100858799(UNC13B) 415413(UNC13C) 430487(UNC13A)
PCOC: 116236099(UNC13A) 116239153 116244676(UNC13C)
MGP: 100547334 100549757(UNC13A) 104912810 104914788
CJO: 107305796(UNC13B) 107318760(UNC13C) 107325608(UNC13A)
NMEL: 110389082(UNC13A) 110389477(UNC13B) 110403660(UNC13C)
APLA: 101793422(UNC13C) 101804257 113840128(UNC13B)
ACYG: 106033673(UNC13C) 106045644 106048543(UNC13B)
TGU: 100220362(UNC13A) 100224334(UNC13B) 100231238(UNC13C)
LSR: 110469501(UNC13A) 110474213(UNC13C) 110484208(UNC13B)
SCAN: 103815995(UNC13C) 103821989(UNC13A) 103822932(UNC13B)
PMOA: 120496372(UNC13A) 120498237(UNC13B) 120509101(UNC13C)
GFR: 102035760(UNC13B) 102038758(UNC13A) 102041441(UNC13C)
FAB: 101806327(UNC13B) 101809474(UNC13C) 101817495(UNC13A)
PHI: 102102462(UNC13A) 102113137(UNC13B) 102113622(UNC13C)
PMAJ: 107209358(UNC13C) 107215362(UNC13A) 107216351(UNC13B)
CCAE: 111933887(UNC13C) 111940356(UNC13A) 111940994(UNC13B)
CCW: 104684019(UNC13C) 104686736(UNC13B) 104696951(UNC13A)
ETL: 114057153(UNC13C) 114068946 114069557(UNC13B) 114070645(UNC13A)
FPG: 101912697(UNC13A) 101918359(UNC13C) 101923350(UNC13B)
FCH: 102047725(UNC13A) 102050044(UNC13B) 102052641(UNC13C)
CLV: 102088947(UNC13C) 102095057(UNC13A) 102097415(UNC13B)
EGZ: 104130895(UNC13C) 104133833(UNC13B) 104135333(UNC13A)
NNI: 104009653(UNC13A) 104011381(UNC13B) 104017153(UNC13C)
ACUN: 113483801(UNC13C) 113489715(UNC13B) 113490443(UNC13A)
PADL: 103916431(UNC13C) 103921919(UNC13A) 103922314(UNC13B)
AAM: 106482753 106492907(UNC13B) 106496557(UNC13C)
ASN: 102379777(UNC13A) 102383518(UNC13C) 102384778(UNC13B)
AMJ: 102557750(UNC13A) 102564081(UNC13C) 102573827(UNC13B)
CPOO: 109307801(UNC13B) 109309003(UNC13C) 109320536
GGN: 109288620(UNC13C) 109294685(UNC13A) 109298152(UNC13B)
PSS: 102454861 102460068(UNC13C) 102462546(UNC13B)
CMY: 102941090(UNC13C) 102942108 102947512(UNC13B)
CPIC: 101936784(UNC13B) 101939310(UNC13A) 101951450(UNC13C)
TST: 117869092(UNC13A) 117878847 117883646(UNC13C)
CABI: 116823567 116834517(UNC13C) 116835817
ACS: 100561674(unc13c) 100565343 103282322 103282718 103283018
PVT: 110074538(UNC13C) 110079307(UNC13A) 110082813(UNC13B)
PBI: 103057839(UNC13C) 103064787(UNC13A) 103065994
PMUR: 107282181(UNC13A) 107283180(UNC13C) 107296951(UNC13B) 107300006 107300086
TSR: 106542895(UNC13C) 106551451 106555404 106555855
PGUT: 117660928(UNC13C) 117677478(UNC13A) 117679737(UNC13B)
PMUA: 114584211(UNC13C) 114588413 114606479(UNC13B)
ZVI: 118077203(UNC13B) 118085996(UNC13A) 118093163(UNC13C)
GJA: 107107447(UNC13A) 107117598(UNC13C)
XLA: 108706831 108711380 108712370 108718947
XTR: 100489443 100492289(unc13a) 100494605(unc13c) 116412604
NPR: 108792854 108796994 108799480 108804232(UNC13C)
DRE: 100329499(unc13bb) 100534673 100535393 101884666 568618(unc13a)
SRX: 107708291 107712779 107713368 107719588 107724981 107729682 107735091(unc13c) 107741279 107744117 107744157 107752132
SANH: 107655208 107659092 107660688 107662500(unc13c) 107665324 107671790 107672597 107672622 107675908 107684986 107684992 107686461 107688005
SGH: 107554226 107555513 107562566 107586430 107595956 107596290 107596898 107597299 107597300 107600875(unc13c)
CCAR: 109044877 109051339 109055488 109057224 109058679 109060786 109067047 109072547
CAUA: 113040026 113040060 113040482 113045219 113048978 113054113 113061422 113061424 113064638 113064946 113075330 113075833 113082034 113096091 113097300 113099334 113109450 113111941 113118084(unc13c)
IPU: 108255548 108264818(unc13c) 108270949 108277117(unc13b) 108280289
PHYP: 113527917 113528156 113533480 113534663(unc13c) 113544078(unc13b)
AMEX: 103026877 103031140 103047397 111188759
EEE: 113575120(unc13b) 113576214 113584686 113586784 113586859 113591823
TRU: 101061525 101064353(unc13a) 101076037 101078171 101078499
TNG: GSTEN00003652G001 GSTEN00003653G001 GSTEN00020103G001 GSTEN00021472G001 GSTEN00028525G001 GSTEN00028577G001 GSTEN00032900G001
LCO: 104919738 104920723 104927702(unc13b) 104929668 104935500
NCC: 104940955 104944421 104956465 104961541 104965126(unc13a) 104965288 104965289
ELY: 117252354 117252770 117253694(unc13a) 117269876(unc13bb) 117272199
PLEP: 121940960(unc13a) 121944715 121950959 121959524 121963669
SLUC: 116037264 116037560 116045139 116063348(unc13a)
ECRA: 117948892 117950713(unc13a) 117954028
PFLV: 114553801 114556266 114561573(unc13a) 114565205 114571179(unc13b)
GAT: 120815736 120823877(unc13a) 120830185 120833683
MSAM: 119884077 119890745 119891218 119900891(unc13a) 119902924 119914513
CUD: 121509581 121512562 121512693(unc13a) 121519896 121525226
MZE: 101463761(unc13b) 101465195 101481162(unc13a) 101482480 101482850
ONL: 100697680 100702202(unc13a) 100704842(unc13c) 100707952 100709582(unc13b)
OAU: 116310043(unc13a) 116318694 116325564 116333366 116333377
OLA: 101157931(unc13c) 101164968(unc13a) 101167071(unc13b) 105356230
OML: 112136336 112147594 112156682(unc13a) 112160546 112163029(unc13bb)
XMA: 102217077 102220203(unc13b) 102224386 102228331 102230312
XCO: 114142934 114146980 114149354 114150584(unc13a) 114154128
XHE: 116718448(unc13c) 116721682 116724899 116725182(unc13a) 116729372
PRET: 103462162(unc13c) 103463658(unc13a) 103474018(unc13b) 103479452
CVG: 107085206(unc13c) 107094673(unc13b) 107095723 107096951 107098387
CTUL: 119773497 119785426 119786455 119792546(unc13a)
NFU: 107384142 107386072 107386073 107393302(unc13a) 107396498(unc13b) 107396706(unc13c)
KMR: 108230730(unc13a) 108232671 108237353 108239455 108244537
ALIM: 106513582(unc13b) 106515017 106518347 106525446 106526424 106527155(unc13c)
AOCE: 111562838(unc13c) 111565599 111572306 111573549 111574472
CSEM: 103379431(unc13c) 103390383(unc13b) 103395938 103399932
POV: 109624845 109625690 109641527 109641758 109645980 109647116
LCF: 108876972 108877282 108880302(unc13b) 108883601 108887158
SDU: 111219163(unc13c) 111229031 111232095 111237509(unc13b)
SLAL: 111655950(unc13b) 111656358 111657477 111658883 111659134 111660929 111667592
XGL: 120789765 120790845(unc13a) 120798614 120804901 120806167
HCQ: 109507438 109513954 109530165(unc13b) 109532368(unc13a)
BPEC: 110158651 110160166(unc13b) 110172422 110174027(unc13a) 110175368
MALB: 109955838 109957290 109960819(unc13b) 109969250 109974175(unc13a)
SASA: 106562407 106563215 106565090 106569526 106570851 106584438 106585885 106587603 106587638 106592186 106600004 106613770
OTW: 112219384 112227319 112227328 112231066 112237791 112238222 112246888 112251552 112260563 112264232
OMY: 110506127 110508422 110509879 110522750 110522920(unc13bb) 110524288(unc13a) 110525085 110526645 110530995 110536437
SALP: 111961532 111964092 111971827 111973915 111976103 111979835 112077541
ELS: 105011550 105014530 105014966(unc13b) 105020519 105022641
SFM: 108919801 108921409 108926721 108929063 108930042 108938954
PKI: 111845002 111846757 111850305 111857778(unc13b) 111860222(unc13a)
LOC: 102687210(unc13c) 102693323(unc13a)
PSPA: 121294842 121299143 121301024 121301272 121306654 121306693 121309409
ARUT: 117401418 117403970 117429276 117962291 117964279 117974004
LCM: 102359084 102360551(UNC13A) 102365057(UNC13C)
CMK: 103177885(unc13b) 103189394(unc13c) 103189689(unc13a)
RTP: 109926673 109931109(unc13a) 109931667
BFO: 118404553
CIN: 100176945
SCLV: 120338476 120344332
SPU: 576527
APLC: 110977314
SKO: 100377818
DME: Dmel_CG2999(unc-13)
DER: 6555838
DSE: 6619490
DSI: Dsimw501_GD24368(Dsim_unc-13)
DYA: Dyak_GE14499
DAN: 6501778
DSR: 110185455
DPO: Dpse_GA22413 Dpse_GA31855
DPE: 6603482
DMN: 108164394 117189218
DWI: 6651488
DGR: Dgri_GH24008 Dgri_GH24009
DMO: Dmoj_GI14058
DAZ: 108617762
DNV: 108655360 108655389 115565293 115565428
DHE: 111593704
MDE: 101887559
LCQ: 111684783 111687737
AGA: AgaP_AGAP000065
ACOZ: 120949155
AARA: 120906853
AAG: 5574316
AALB: 109424983 109431126
CQU: CpipJ_CPIJ006394
CPII: 120413281
AME: 100577517
ACER: 107995194 108001507
BIM: 100744677
BTER: 100650524
CCAL: 108632717
OBB: 114873991
MGEN: 117219026 117223066
NMEA: 116428658
CGIG: 122401500 122401501
SOC: 105194478
MPHA: 105832861 105835854 105837479
AEC: 105148454
ACEP: 105619068
PBAR: 105428060
VEM: 105570389
HST: 105181265
DQU: 106745134
CFO: 105254874
FEX: 115237569 115237571
LHU: 105678225
PGC: 109858754
OBO: 105274478
PCF: 106785859
NVI: 100680292 107981437
CSOL: 105366156
MDL: 103570661 106693679
TCA: 658165
DPA: 109542778
ATD: 109604180
AGB: 108910349
NVL: 108564037
APLN: 108741634
PPYR: 116166509 116166817 116167227
OTU: 111413691
BMOR: 101743696
BMAN: 114248270
MSEX: 115440116
DPL: KGM_204826 KGM_204827
BANY: 112046768
PMAC: 106710037
PPOT: 106104848
PXU: 106119419
PRAP: 111003573
ZCE: 119839549
HAW: 110384263
TNL: 113503452
PXY: 105391455
API: 100159009
DNX: 107165401
AGS: 114122033
RMD: 113553468
BTAB: 109036269
CLEC: 106667999
NLU: 111055574
PHU: Phum_PHUM432180
ZNE: 110831305
CSEC: 111863312
FCD: 110855498 110862265
DPX: DAPPUDRAFT_60333
PVM: 113815928
HAME: 121856280 121865276
EAF: 111708785
ISC: IscW_ISCW023875
DSV: 119443015
RSAN: 119388162
RMP: 119186565
VDE: 111254901
VJA: 111260672 111272144
TUT: 107368708
DPTE: 113793680 113794312
CSCU: 111624581
PTEP: 107444247
SDM: 118189412
CEL: CELE_ZK524.2(unc-13)
CBR: CBG11942(Cbr-unc-13) CBG11945
BMY: BM_BM7972(Bma-unc-13)
LOA: LOAG_18413
NAI: NECAME_11523
TSP: Tsp_11658
HRO: HELRODRAFT_162287 HELRODRAFT_186739
LGI: LOTGIDRAFT_157505
PCAN: 112554604
BGT: 106073711
GAE: 121384461
CRG: 105330539
MYI: 110456312
PMAX: 117335123
OBI: 106879696
LAK: 106182076
SMM: Smp_134590 Smp_172040
OVI: T265_04621 T265_14218
EGL: EGR_04296 EGR_09651
NVE: 5500960 5503043
EPA: 110241583
ATEN: 116303644
ADF: 107333631
AMIL: 114961819
PDAM: 113672644
SPIS: 111329162
DGT: 114522532
HMG: 100215891
TAD: TRIADDRAFT_22095
AQU: 100634159
 » show all
Reference
  Authors
Martin TF
  Title
Prime movers of synaptic vesicle exocytosis.
  Journal
Neuron 34:9-12 (2002)
DOI:10.1016/S0896-6273(02)00651-7
Reference
  Authors
Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, Reim K, Rosenmund C
  Title
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.
  Journal
Proc Natl Acad Sci U S A 99:9037-42 (2002)
DOI:10.1073/pnas.122623799
  Sequence
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