KEGG   ORTHOLOGY: K15907
Entry
K15907                      KO                                     

Name
ptlI, CYP183A
Definition
pentalenene oxygenase [EC:1.14.15.32]
Pathway
ko00909  Sesquiterpenoid and triterpenoid biosynthesis
ko00999  Biosynthesis of various secondary metabolites - part 1
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00819  Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K15907  ptlI, CYP183A; pentalenene oxygenase
  09110 Biosynthesis of other secondary metabolites
   00999 Biosynthesis of various secondary metabolites - part 1
    K15907  ptlI, CYP183A; pentalenene oxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K15907  ptlI, CYP183A; pentalenene oxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.32  pentalenene oxygenase
     K15907  ptlI, CYP183A; pentalenene oxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, bacteria type
  CYP183 family
   K15907  ptlI, CYP183A; pentalenene oxygenase
Other DBs
RN: R09814
COG: COG2124
Genes
SMA: SAVERM_2999(ptlI)
SCT: SCAT_p0090(ptlI)
SCY: SCATT_p16540
SBH: SBI_09680(cyp48)
SDV: BN159_1442(ptlI)
SCI: B446_29700
SCW: TU94_27410
SLE: sle_13150(sle_13150)
SCLF: BB341_00225
SSIA: A7J05_09235
SALF: SMD44_00690(ptlI)
SALJ: SMD11_0076(ptlI) SMD11_6153(ptlI)
KSK: KSE_03600
 » show all
Reference
  Authors
Quaderer R, Omura S, Ikeda H, Cane DE
  Title
Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlI, a cytochrome P450 of Streptomyces avermitilis.
  Journal
J Am Chem Soc 128:13036-7 (2006)
DOI:10.1021/ja0639214
  Sequence
LinkDB

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