KEGG   ORTHOLOGY: K15959
Entry
K15959            Tight     KO                                     
Symbol
mtmMI
Name
O-methyltransferase [EC:2.1.1.-]
Pathway
map01057  Biosynthesis of type II polyketide products
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00782  Mithramycin biosynthesis, 4-demethylpremithramycinone => mithramycin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15959  mtmMI; O-methyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K15959  mtmMI; O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     K15959  mtmMI; O-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Methylase
   K15959  mtmMI; O-methyltransferase
Other DBs
RN: R06715
Genes
AG: CAK50791(mtmMI)
Reference
  Authors
Lozano MJ, Remsing LL, Quiros LM, Brana AF, Fernandez E, Sanchez C, Mendez C, Rohr J, Salas JA
  Title
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.
  Journal
J Biol Chem 275:3065-74 (2000)
DOI:10.1074/jbc.275.5.3065
  Sequence
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