KEGG   ORTHOLOGY: K15994
Entry
K15994            Tight     KO                                     

Name
tylCV
Definition
demethyllactenocin mycarosyltransferase [EC:2.4.1.318]
Pathway
ko00522  Biosynthesis of 12-, 14- and 16-membered macrolides
ko01052  Type I polyketide structures
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00773  Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K15994  tylCV; demethyllactenocin mycarosyltransferase
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K15994  tylCV; demethyllactenocin mycarosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.318  demethyllactenocin mycarosyltransferase
     K15994  tylCV; demethyllactenocin mycarosyltransferase
Other DBs
RN: R06452
CAZy: GT1
Genes
AG: AAD41824(tylCV)
Reference
  Authors
Rawlings BJ.
  Title
Type I polyketide biosynthesis in bacteria (part B).
  Journal
Nat Prod Rep 18:231-81 (2001)
DOI:10.1039/B100191O
Reference
  Authors
Bate N, Butler AR, Smith IP, Cundliffe E
  Title
The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin.
  Journal
Microbiology 146 ( Pt 1):139-46 (2000)
DOI:10.1099/00221287-146-1-139
  Sequence
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