KEGG   ORTHOLOGY: K16060
Entry
K16060                      KO                                     

Name
BIRC2_3
Definition
baculoviral IAP repeat-containing protein 2/3
Pathway
ko01524  Platinum drug resistance
ko04064  NF-kappa B signaling pathway
ko04120  Ubiquitin mediated proteolysis
ko04210  Apoptosis
ko04215  Apoptosis - multiple species
ko04217  Necroptosis
ko04390  Hippo signaling pathway
ko04510  Focal adhesion
ko04621  NOD-like receptor signaling pathway
ko04624  Toll and Imd signaling pathway
ko04668  TNF signaling pathway
ko05132  Salmonella infection
ko05145  Toxoplasmosis
ko05168  Herpes simplex virus 1 infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04064 NF-kappa B signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04668 TNF signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04215 Apoptosis - multiple species
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04217 Necroptosis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09150 Organismal Systems
  09151 Immune system
   04624 Toll and Imd signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04621 NOD-like receptor signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   05202 Transcriptional misregulation in cancer
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I32: IAP family
   K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
Other DBs
GO: 0043027
Genes
HSA: 329(BIRC2) 330(BIRC3)
PTR: 451507(BIRC3) 451508(BIRC2)
PPS: 100970636(BIRC2) 100971429(BIRC3)
GGO: 101126938(BIRC3) 101127675(BIRC2)
PON: 100457249(BIRC3) 100457858(BIRC2)
NLE: 100579740(BIRC3) 100580307(BIRC2)
MCC: 702468(BIRC3) 702592(BIRC2)
MCF: 102137780(BIRC3) 102138168(BIRC2)
CSAB: 103248332(BIRC3) 103248333(BIRC2)
RRO: 104674657(BIRC3) 104674658(BIRC2)
RBB: 108514076(BIRC2) 108514077(BIRC3)
CJC: 100394418(BIRC2)
SBQ: 101027816(BIRC2) 101043827(BIRC3)
MMU: 11796(Birc3) 11797(Birc2)
MCAL: 110301861(Birc2) 110302303
RNO: 60371(Birc2) 78971(Birc3)
MUN: 110553751(Birc3) 110553757
CGE: 100756596(Birc2) 100761700
NGI: 103731538(Birc2) 103746493(Birc3)
HGL: 101718804(Birc2) 101719143(Birc3)
CCAN: 109689097(Birc2) 109689098(Birc3)
OCU: 100338118(BIRC2) 100340120(BIRC3)
TUP: 102493795(BIRC2) 102494213(BIRC3)
CFA: 479464(BIRC2) 489433(BIRC3)
VVP: 112925935(BIRC3) 112925936(BIRC2)
UMR: 103662462(BIRC2) 103662463
UAH: 113260143(BIRC2) 113260144
ORO: 101372845(BIRC3) 101373139(BIRC2)
FCA: 101083444 101101663(BIRC2)
PTG: 102951731(BIRC3) 102972419(BIRC2)
PPAD: 109257521 109257526(BIRC2)
AJU: 106976507 106976508(BIRC2)
BTA: 514386(BIRC3) 539314(BIRC2)
BOM: 102269806(BIRC3) 102286771(BIRC2)
BIU: 109555878 109568764(BIRC3) 109569840(BIRC2)
BBUB: 102394110(BIRC3) 102394850
CHX: 102173485(BIRC2) 102173952(BIRC3)
OAS: 101119930(BIRC2) 101120189(BIRC3)
SSC: 100622590(BIRC3) 100622859
CFR: 102513751 102513991(BIRC2)
CDK: 105087177(BIRC2) 105087178(BIRC3)
BACU: 103006934(BIRC3) 103007434(BIRC2)
LVE: 103086871(BIRC3) 103087142(BIRC2)
OOR: 101276394(BIRC3) 101276649(BIRC2)
DLE: 111168369(BIRC2) 111168370(BIRC3)
PCAD: 102981700(BIRC3) 102981991(BIRC2)
ECB: 100061273(BIRC2) 100068894(BIRC3)
EPZ: 103552625(BIRC3) 103552627(BIRC2)
EAI: 106845876(BIRC3) 106845877
MYB: 102240943(BIRC3) 102241248(BIRC2)
MYD: 102771967(BIRC2) 102772449(BIRC3)
MNA: 107532417(BIRC2) 107532418
PALE: 102884388 102884651(BIRC2)
RAY: 107504640 107504641(BIRC2)
MJV: 108389053(BIRC3) 108389075(BIRC2)
MDO: 100010741 100010782(BIRC2)
OAA: 100077243
GGA: 374012(BIRC2)
MGP: 100543708(BIRC2)
CJO: 107308397(BIRC2)
NMEL: 110389900(BIRC2)
APLA: 101793263(BIRC2)
ACYG: 106034170(BIRC2)
TGU: 100225317(BIRC2)
LSR: 110470015
SCAN: 103827281
GFR: 102031819
FAB: 101821374(BIRC2)
PHI: 102110239(BIRC2)
PMAJ: 107210777(BIRC2)
CCAE: 111924350(BIRC2)
CCW: 104690066
ETL: 114067044(BIRC2)
FPG: 101924079(BIRC2)
FCH: 102051620(BIRC2)
CLV: 102090342
EGZ: 104128906(BIRC2)
NNI: 104023072(BIRC2)
ACUN: 113491430
PADL: 103918923(BIRC2)
AAM: 106495530(BIRC2)
ASN: 102368067
AMJ: 102562735(BIRC2)
PSS: 102448753
CMY: 102941252
CPIC: 101948146
ACS: 100554030(birc2)
PVT: 110080243(BIRC2)
PBI: 103052845(BIRC2)
PMUR: 107286355
TSR: 106549668
PMUA: 114595659(BIRC2)
XLA: 100036859(birc2.S) 108703748 446568(birc2.L)
XTR: 108648784 448041(birc2)
NPR: 108786933
DRE: 373107(birc2)
IPU: 100304597(birc2)
PHYP: 113541487(birc2)
AMEX: 103025481(birc2)
EEE: 113573611(birc2)
TRU: 101075537
LCO: 104934542
NCC: 104964663(birc2)
MZE: 101484124
ONL: 100705328
OLA: 101172600
XMA: 102228638(birc2)
XCO: 114153415(birc2)
PRET: 103475480(birc2)
CVG: 107098510(birc2)
NFU: 107387009(birc2)
KMR: 108237026
ALIM: 106514085(birc2)
AOCE: 111580650
CSEM: 103395117(birc2)
POV: 109628681
LCF: 108893387
SDU: 111234415
SLAL: 111666176
HCQ: 109509764
BPEC: 110158425
MALB: 109959278
SALP: 112072902
ELS: 105006427(birc2)
SFM: 108934246
PKI: 111838067
LCM: 102364182(BIRC2)
CMK: 103177430(birc2)
RTP: 109939041
CIN: 100175293 100182621 100183688 778881(zf(ring)-14)
SPU: 581540
APLC: 110981472
SKO: 100378904
DME: Dmel_CG8293(Diap2)
DER: 6548868
DSE: 6609342
DSI: Dsimw501_GD25587(Dsim_GD25587)
DYA: Dyak_GE14118(Dyak_Iap2)
DAN: 6496179
DSR: 110178237
DPE: 6603157
DWI: 6640629
DAZ: 108617526
DNV: 108653986
DHE: 111599683
DVI: 6627156
MDE: 101900624
AAG: 5568196
AALB: 109402332
AME: 413374
BIM: 100741028
BTER: 100647366
OBB: 114879108
SOC: 105199677
MPHA: 105829200
AEC: 105148032
ACEP: 105623438
PBAR: 105422658
VEM: 105567055
HST: 105182143
DQU: 106751808
CFO: 105249204
LHU: 105676081
OBO: 105282023
PCF: 106791785
NVI: 100122438
CSOL: 105359266
TCA: 663905(Tiap2)
DPA: 109534605
ATD: 109596674
NVL: 108568147
BMOR: 100529214(iap2)
BMAN: 114245563
PMAC: 106714052
PRAP: 110993152
HAW: 110383246
TNL: 113498337
API: 100159034
RMD: 113556228
CLEC: 106669703
ZNE: 110838931
CSCU: 111635727
PTEP: 107447772
NVE: 5501165
EPA: 110251845
ADF: 107347984
AMIL: 114959586
PDAM: 113672022
SPIS: 111334213
DGT: 114536589
 » show all
Reference
PMID:8643514
  Authors
Uren AG, Pakusch M, Hawkins CJ, Puls KL, Vaux DL
  Title
Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.
  Journal
Proc Natl Acad Sci U S A 93:4974-8 (1996)
DOI:10.1073/pnas.93.10.4974
  Sequence
[hsa:329 330]
Reference
  Authors
Dubrez-Daloz L, Dupoux A, Cartier J
  Title
IAPs: more than just inhibitors of apoptosis proteins.
  Journal
Cell Cycle 7:1036-46 (2008)
DOI:10.4161/cc.7.8.5783
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