KEGG   ORTHOLOGY: K16245
Entry
K16245                      KO                                     
Symbol
dmpO, poxE, tomA4
Name
phenol/toluene 2-monooxygenase (NADH) P4/A4 [EC:1.14.13.244 1.14.13.243]
Pathway
map00361  Chlorocyclohexane and chlorobenzene degradation
map00362  Benzoate degradation
map00623  Toluene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00548  Benzene degradation, benzene => catechol
Reaction
R03560  toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating)
R03608  o-cresol,NADH:oxygen oxidoreductase (2,3-dihydroxylating)
R10042  benzene,NADH:oxygen oxidoreductase
R10043  phenol,NADH:oxygen oxidoreductase (2-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4
   00623 Toluene degradation
    K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.243  toluene 2-monooxygenase
     K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4
    1.14.13.244  phenol 2-monooxygenase (NADH)
     K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4
Genes
PSD: DSC_04420
RTH: LRK53_10155
RBD: ALSL_0897
PRE: PCA10_07000(dmpO)
PFUW: KF707C_6730(dmpO)
PCQ: PcP3B5_25340
PPG: PputGB1_3307
PPJ: RK21_04243
PVR: PverR02_14675
PKC: PKB_1745
PALK: PSAKL28_05910
PALL: UYA_20185
PUM: HGP31_14985
PLAL: FXN65_03430
PPHN: HU825_05000
PIZ: LAB08_R22520
PKM: PZ739_17295
PKK: QQ992_10230
AVN: Avin_08820(dmpO) Avin_30720(lapO)
AVL: AvCA_08820(dmpO) AvCA_30720(lapO)
AVD: AvCA6_08820(dmpO) AvCA6_30720(lapO)
HPEG: EAO82_09395
HAES: LO767_17640
PPHA: BVH74_06125
MAD: HP15_4028
MSR: AU15_20695
MLQ: ASQ50_09245
MSQ: BKP64_13880
MARJ: MARI_05370
MALL: PBN92_01640
MSHE: MAALD49_03370(mphO) MAALD49_03800(mphO)
MANP: EHN06_02415
PSPG: AK823_07305
PSYG: AK825_07400
ABK: LX00_05870
ABAU: IX87_04555
ACC: BDGL_000471(mphO)
ALC: OTEC02_12960
ASEI: I8T81_12975
ACD: AOLE_13315
AJO: RZ95_18645
ACW: A0J50_11615
ALA: BFG52_11015
ADV: DJ533_01820 DJ533_11010
AWU: BEN71_12700
AGU: AS4_16420(dsoE)
ABER: BSR55_16105
ACHI: CDG60_14315
ATG: J4G44_06380
ACIU: A3K93_13810
AFUS: EYZ66_02630
CZA: CYCME_2108
BLEP: AL038_01330
THIS: HZT40_13290
TBN: TBH_C0909
MARS: A8C75_10410
MGEO: CFI10_13965
MSEC: LN244_11605
MRZ: KDW95_03650
NCU: F0U83_03020
NJP: NEJAP_0666(dmpO)
NIK: F5I99_10135
AJP: AMJAP_3007(dmpO)
SINI: GT972_13695
NZO: SAMEA4504057_0441
NCI: NCTC10296_00920
NWD: H3L96_04790
NDU: LVJ88_00565
VFF: VITFI_CDS1385
PTES: JQU52_04835
USU: LVJ78_03635
AQL: BXU06_12770 BXU06_16835
RPI: Rpic_4627
RPF: Rpic12D_3551
RPJ: N234_08125
REH: H16_B0543(poxE)
CNC: CNE_2c04890(poxE)
REU: Reut_A1703 Reut_B5684
RME: Rmet_1327(tomA4) Rmet_1783(phyD)
CBW: RR42_s2489
CCUP: BKK81_27065
CUP: BKK80_29255
CUU: BKK79_35205
COX: E0W60_07750
CCAX: KZ686_09960
CUK: KB879_20165
BVI: Bcep1808_7597
BUR: Bcep18194_B2967
BCEN: DM39_4840(phO)
BCT: GEM_5409
BCED: DM42_4999(phO)
BCON: NL30_24630
BDF: WI26_15955
BTEI: WS51_00530
BPSL: WS57_12195
BSTL: BBJ41_10480
BANN: JFN94_19095
BYI: BYI23_C000530
BUE: BRPE67_CCDS12540
BUZ: AYM40_16200
PARB: CJU94_38085
PTER: C2L65_07825
PPK: U875_01930
PRB: X636_07540
LIMN: HKT17_03885
BOJ: CBF45_04545
APES: FOC84_00360
CDN: BN940_04346
AFA: UZ73_17850
AFQ: AFA_08535
AAQU: D3M96_09755
AAMM: FE795_07750
PIG: EGT29_26540
KGY: EHF36_04930
AJS: Ajs_0210
ACID: CBP33_01055
ACIP: CBP36_01155
ACIN: CBP34_01065
ACIS: CBP35_17795
AMON: H9L24_14240
VEI: Veis_2792
CTT: CtCNB1_3158
COF: FOZ74_08270
ADN: Alide_0327
ADK: Alide2_0274
OTD: J1M35_00085
HYL: LPB072_18145
HPSE: HPF_01910(tbuD)
HYN: F9K07_02715
HTN: KI616_02000
DIH: G7047_01710
DRG: H9K76_11605
SIMP: C6571_13585
MELA: C6568_07890
MJE: LVC68_00970
STHM: IS481_10495
SAQA: OMP39_09075
MPT: Mpe_A2281(dmpO) Mpe_A3305(dmpO)
METP: C1M51_06255 C1M51_06280 C1M51_15440
SNN: EWH46_19250
IDC: LRM40_19530
LCH: Lcho_3359
MASW: AM586_18625
TMJ: P0M04_30690
RBU: PG1C_06890
DAR: Daro_3793
DEY: HYN24_14140 HYN24_14255
DDEN: KI615_16925
DECH: GBK02_02795
QAU: KI612_13865
FLE: KI610_15390 KI610_15505
AZO: azo1849(lapO) azo2440(poxE)
AOA: dqs_1999 dqs_2584
AZD: CDA09_10270 CDA09_10425
AZR: CJ010_12210 CJ010_15250
TMZ: Tmz1t_3112
THU: AC731_001780
THK: CCZ27_10680 CCZ27_10785
THAU: C4PIVTH_2796(dmpO)
AZQ: G3580_00485 G3580_01310 G3580_08225
MTUN: MTUNDRAET4_3885
MAAD: AZF01_11215
MLUT: JET14_11660
SMY: BJP26_18685
SHAN: PPZ50_08290
SJP: SJA_C1-12020(tomA4)
SINB: SIDU_08255
SYB: TZ53_09085
SUFL: FIL70_18930
SBAR: H5V43_20580
ACIB: ACBT_0276(dmpO)
AFC: AFAEC_1854(dmpO)
AAQI: AAQM_0973(dmpO)
ACLO: ACLO_a0151(dmpO)
ADZ: ADFLV_2565(dmpO)
ARC: ABLL_2456
AROS: NJU99_01610
ALK: ALEK_0374(dmpO)
AANA: AANAER_1249(dmpO)
SAY: TPY_0631
SAP: Sulac_3008
MSA: Mycsm_01967
MLL: B1R94_25100
GOQ: ACH46_03540
GOC: CXX93_06745
GAM: GII34_22045
GSI: P5P27_15495
TOY: FO059_13980
JTE: ASJ30_00075
JLI: EXU32_15390
JME: EEW87_015380
JCR: O9K63_12560
PHW: G7075_13210
AUS: IPK37_11625
TCU: Tcur_0527
AACD: LWP59_26110 LWP59_38100
PDX: Psed_0767
AG: BAA23334(dsoE)
 » show all
Reference
PMID:2254258
  Authors
Nordlund I, Powlowski J, Shingler V
  Title
Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.
  Journal
J Bacteriol 172:6826-33 (1990)
DOI:10.1128/jb.172.12.6826-6833.1990
  Sequence
[ppj:RK21_04243]
Reference
PMID:11751810
  Authors
Canada KA, Iwashita S, Shim H, Wood TK
  Title
Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation.
  Journal
J Bacteriol 184:344-9 (2002)
DOI:10.1128/jb.184.2.344-349.2002
  Sequence
[bvi:Bcep1808_7597]
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