KEGG   ORTHOLOGY: K16333
Entry
K16333                      KO                                     

Name
CRTC2, TORC2
Definition
CREB-regulated transcription coactivator 2
Pathway
ko04151  PI3K-Akt signaling pathway
ko04152  AMPK signaling pathway
ko04922  Glucagon signaling pathway
ko04931  Insulin resistance
ko05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
   04152 AMPK signaling pathway
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
Genes
HSA: 200186(CRTC2)
PTR: 738694(CRTC2)
PPS: 100976458(CRTC2)
GGO: 101149666(CRTC2)
PON: 100438416(CRTC2)
NLE: 100597840(CRTC2)
MCC: 715908(CRTC2)
MCF: 102137277(CRTC2)
CSAB: 103223939(CRTC2)
RRO: 104663514(CRTC2)
RBB: 108518844(CRTC2)
CJC: 103789006(CRTC2)
SBQ: 101040859(CRTC2)
MMU: 74343(Crtc2)
MCAL: 110291453(Crtc2)
MPAH: 110320038(Crtc2)
RNO: 310615(Crtc2)
MUN: 110554243(Crtc2)
CGE: 100751848(Crtc2)
NGI: 103751715(Crtc2)
HGL: 101709168(Crtc2)
CCAN: 109688050(Crtc2)
OCU: 100358960(CRTC2)
TUP: 102481058(CRTC2)
CFA: 612305(CRTC2)
VVP: 112918870(CRTC2)
AML: 100472270(CRTC2)
UMR: 103668413(CRTC2)
UAH: 113245327(CRTC2)
ORO: 101383200(CRTC2)
ELK: 111138927
FCA: 101101104(CRTC2)
PTG: 102953123(CRTC2)
PPAD: 109256187
BTA: 540959(CRTC2)
BOM: 102280934(CRTC2)
BIU: 109554474(CRTC2)
BBUB: 102397007(CRTC2)
CHX: 102180907(CRTC2)
OAS: 101102117(CRTC2)
SSC: 100519835(CRTC2)
CFR: 102515899(CRTC2)
CDK: 105089365(CRTC2)
BACU: 103004880(CRTC2)
LVE: 103086651(CRTC2)
OOR: 101287600(CRTC2)
DLE: 111167180(CRTC2)
PCAD: 112061832(CRTC2)
ECB: 100056571(CRTC2)
EPZ: 103555397(CRTC2)
EAI: 106846251(CRTC2)
MYB: 102257000(CRTC2)
MYD: 102770919(CRTC2)
MNA: 107543902(CRTC2)
HAI: 109373525(CRTC2)
DRO: 112316349(CRTC2)
PALE: 102879203(CRTC2)
RAY: 107509408(CRTC2)
MJV: 108408207(CRTC2)
LAV: 100673108(CRTC2)
TMU: 101344998
MDO: 100019951(CRTC2)
SHR: 100922824(CRTC2)
PCW: 110211993(CRTC2)
OAA: 114808055(CRTC2)
CJO: 107324475(CRTC2)
TGU: 100221000(CRTC2)
LSR: 110476855(CRTC2)
SCAN: 108964479
FAB: 101816291(CRTC2)
PHI: 102110933(CRTC2)
PMAJ: 107214640(CRTC2)
FPG: 101923752(CRTC2)
FCH: 102050437(CRTC2)
CLV: 110364232(CRTC2)
EGZ: 104123012(CRTC2)
NNI: 104018282(CRTC2)
AAM: 106484278(CRTC2)
ASN: 102372662(CRTC2)
AMJ: 102571416(CRTC2)
CMY: 102939459(CRTC2)
CPIC: 101942224(CRTC2)
PVT: 110088491(CRTC2)
PBI: 103055527(CRTC2)
PMUR: 107285215(CRTC2)
TSR: 106552862
PMUA: 114586231
GJA: 107110880(CRTC2)
XTR: 101733698(crtc2)
DRE: 108179660
SRX: 107745155
CCAR: 109073074
IPU: 108256981 108267545(crtc2)
TRU: 101063579(crtc2)
MZE: 101479703(crtc2)
ONL: 100694646(crtc2)
OLA: 101166701
XMA: 102220988(crtc2)
XCO: 114141694(crtc2)
PRET: 103477480(crtc2)
CVG: 107095534(crtc2)
NFU: 107378893
KMR: 108229424
AOCE: 111568265
CSEM: 103388972(crtc2)
POV: 109646180
LCF: 108884694
SDU: 111234090
HCQ: 109512134(crtc2)
BPEC: 110157907
MALB: 109970057
ELS: 105012688(crtc2) 105019155
SFM: 108941900
PKI: 111838365(crtc2) 111848277
LCM: 102352254(CRTC2)
RTP: 109926463
 » show all
Reference
  Authors
Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M
  Title
TORCs: transducers of regulated CREB activity.
  Journal
Mol Cell 12:413-23 (2003)
DOI:10.1016/j.molcel.2003.08.013
Reference
  Authors
Iourgenko V, Zhang W, Mickanin C, Daly I, Jiang C, Hexham JM, Orth AP, Miraglia L, Meltzer J, Garza D, Chirn GW, McWhinnie E, Cohen D, Skelton J, Terry R, Yu Y, Bodian D, Buxton FP, Zhu J, Song C, Labow MA
  Title
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.
  Journal
Proc Natl Acad Sci U S A 100:12147-52 (2003)
DOI:10.1073/pnas.1932773100
  Sequence
[hsa:200186]
LinkDB

DBGET integrated database retrieval system