KEGG   ORTHOLOGY: K17476
Entry
K17476                      KO                                     

Name
penM, pntM, CYP161C
Definition
pentalenolactone synthase [EC:1.14.19.8]
Pathway
ko00999  Biosynthesis of various secondary metabolites - part 1
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00819  Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00999 Biosynthesis of various secondary metabolites - part 1
    K17476  penM, pntM, CYP161C; pentalenolactone synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17476  penM, pntM, CYP161C; pentalenolactone synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.8  pentalenolactone synthase
     K17476  penM, pntM, CYP161C; pentalenolactone synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, bacteria type
  CYP161 family
   K17476  penM, pntM, CYP161C; pentalenolactone synthase
Other DBs
RN: R10162
COG: COG2124
Genes
SBH: SBI_09672(cyp47)
SCW: TU94_27370
SLE: sle_13230(sle_13230)
SSIA: A7J05_09275
AG: ADO85571(pntM) ADO85587(penM)
Reference
  Authors
Zhu D, Seo MJ, Ikeda H, Cane DE
  Title
Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.
  Journal
J Am Chem Soc 133:2128-31 (2011)
DOI:10.1021/ja111279h
  Sequence
LinkDB

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