KEGG   ORTHOLOGY: K17751
Entry
K17751                      KO                                     

Name
MYH6_7
Definition
myosin heavy chain 6/7
Pathway
ko04022  cGMP-PKG signaling pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04919  Thyroid hormone signaling pathway
ko05410  Hypertrophic cardiomyopathy
ko05414  Dilated cardiomyopathy
ko05416  Viral myocarditis
Disease
H00292  Hypertrophic cardiomyopathy
H00294  Dilated cardiomyopathy
H00546  Atrial septal defect
H00594  Distal myopathy
H00656  Scapuloperoneal myopathy
H00703  Myosin storage myopathy
H01216  Left ventricular noncompaction
H01977  Laing distal myopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K17751  MYH6_7; myosin heavy chain 6/7
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K17751  MYH6_7; myosin heavy chain 6/7
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K17751  MYH6_7; myosin heavy chain 6/7
   04261 Adrenergic signaling in cardiomyocytes
    K17751  MYH6_7; myosin heavy chain 6/7
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K17751  MYH6_7; myosin heavy chain 6/7
   05414 Dilated cardiomyopathy
    K17751  MYH6_7; myosin heavy chain 6/7
   05416 Viral myocarditis
    K17751  MYH6_7; myosin heavy chain 6/7
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K17751  MYH6_7; myosin heavy chain 6/7
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K17751  MYH6_7; myosin heavy chain 6/7
Genes
HSA: 4624(MYH6) 4625(MYH7)
PTR: 452801(MYH6) 745215(MYH7)
PPS: 100978192(MYH6) 100978529(MYH7)
GGO: 101138909 101143194
PON: 100448481(MYH6) 100448828
NLE: 100599213 100601359
MCC: 100428939 713471(MYH6)
MCF: 102118251(MYH6) 102118628(MYH7)
CSAB: 103231478(MYH6) 103231480(MYH7)
RRO: 104664872 104674161
RBB: 108523551 108523597(MYH6)
CJC: 100400067(MYH6) 100400430(MYH7)
SBQ: 101027633(MYH7) 101027939(MYH6)
MMU: 140781(Myh7) 17888(Myh6)
MCAL: 110309088(Myh7) 110309092(Myh6)
MPAH: 110325261(Myh7) 110325318(Myh6)
RNO: 29556(Myh6) 29557(Myh7)
MUN: 110542857 110566645
CGE: 100770130 100772734
NGI: 103739453(Myh6) 103739454(Myh7)
HGL: 101707190(Myh7) 101707554(Myh6)
CCAN: 109697767(Myh6) 109697768(Myh7)
OCU: 100125987(MYH6)
TUP: 102484562(MYH6) 102485681(MYH7)
CFA: 100685644(MYH6) 403807(MYH7)
VVP: 112926472 112926516
AML: 100469933 100470185(MYH6)
UMR: 103681067(MYH6) 103681068
UAH: 113245998 113246045
ORO: 101385604(MYH7) 101385904(MYH6)
ELK: 111158831
FCA: 101095986(MYH6) 101096736
PTG: 102955104(MYH7)
AJU: 106979458
BTA: 100296004(MYH6) 282714(MYH7)
BOM: 102272267(MYH6) 102273976(MYH7)
BIU: 109564796
BBUB: 102401416(MYH6) 102413515
CHX: 102181869(MYH7) 106502520
OAS: 101120580 442995
SSC: 100736765 396860(MYH7)
CFR: 102504269(MYH6) 102514829
CDK: 105098287 105106562
BACU: 103014002(MYH7) 103020695(MYH6)
LVE: 103090453(MYH7) 103090716(MYH6)
OOR: 101290098(MYH7) 101290350(MYH6)
PCAD: 102978583 102979950(MYH6) 114487067
ECB: 111767446(MYH6) 791234(MYH7)
EPZ: 103563014 103563015
EAI: 106840636
MYB: 102249796(MYH7) 102250088(MYH6)
MYD: 102759546(MYH6) 102763864(MYH7)
MNA: 107531658 107531708(MYH6)
HAI: 109393614 109393661
DRO: 112300691(MYH7) 112301295
PALE: 102879915(MYH7) 102880161
RAY: 107498010(MYH6) 107498011
MJV: 108400003
LAV: 100670087 100670377
TMU: 101353289
MDO: 100024758(MYH7) 100030608(MYH6)
SHR: 100925998 100935261(MYH6)
PCW: 110193568(MYH7) 110193748(MYH6)
OAA: 100088789 100089536(MYH6)
GGA: 395350(MYH7) 429272(MYO7L2)
MGP: 100545344 100549331
CJO: 107306777 107322603
NMEL: 110391953 110407856
TGU: 100229852 100230474 115493804
LSR: 110479530 110479532 110481825 116183099
SCAN: 103815434 103815441 103825210
GFR: 102040228 102041027
FAB: 101807739 101809654(MYH7)
PHI: 102102789 102107249 102107556(MYH7)
PMAJ: 107199261 107215968 107215970
CCAE: 111922638 111925389 111944670
CCW: 104685869 104685921
ETL: 114055155 114055158 114072520
FPG: 101919808(MYH6)
CLV: 102088960 102098265
EGZ: 104123279
AAM: 106484950
ASN: 102378097 102378497
AMJ: 102576117(MYH6)
PSS: 102450688 102455980
CMY: 102943726(MYH7) 102948216(MYH6)
CPIC: 101942994(MYH7) 101943457(MYH6)
ACS: 100567487(myh7) 100567683
PVT: 110087834 110087836
PBI: 103065114 103065347
PMUR: 107293090 107293091
PMUA: 114581469 114583613
GJA: 107105618 107107576
XLA: 108707020 108714867 108714868 432141(myh6.S)
XTR: 100216059(myh6) 100485637
NPR: 108786749(MYH7) 108786757
DRE: 100124599(smyhc2) 100329748 100329813 30616(myh7) 321552(smyhc1) 386711(myh6) 768300(myh7l)
SRX: 107722552 107753078 107753080
SANH: 107676815 107680223 107680224 107686843 107686853 107687159 107688458
SGH: 107560354 107560364 107560365 107560368 107586102 107589804 107589805
CCAR: 109050073 109050079
IPU: 108261464 108261465 108271481 108271487 108271488 108280896
PHYP: 113526615 113526616 113526618 113543184
AMEX: 103031694 103040277 103041884 111193355
EEE: 113568155 113570510 113572963 113572964 113572973 113585001
TRU: 100462945 101064672 101067216 780532
TNG: GSTEN00006200G001 GSTEN00008412G001
LCO: 104927528 104934815 104934821 104940148
NCC: 104941941 104942661 104942663 104965207
MZE: 101463895 101470061 101483728 101484004 105941235
ONL: 100707241 100711599 100712135 106098809 106098811
OLA: 100125526 100415781(vmhc) 101156287 101157595 101164097
XMA: 102229576 102230019 102232694 102232954
XCO: 114136525 114146201 114146202 114146203 114146204
PRET: 103479335 103479338 103482310
CVG: 107088600 107088601 107088603 107095245
NFU: 107384188 107384189 107384191 107384435
KMR: 108229141 108229685 108251423(myh6)
ALIM: 106514903 106514905
AOCE: 111583263 111583281 111583290 111583297 111587068
CSEM: 103381356 103396567 103396568 103396570 103396571
POV: 109629688 109638373 109640947
LCF: 108874635 108874636 108884480 108884482 108898235
SDU: 111223819 111223820 111223821 111223822 111240132 111240133
SLAL: 111648209 111669807 111669811 111669812
HCQ: 109524130 109524131 109524132
BPEC: 110160808 110170424 110170425
MALB: 109974384 109974385
SASA: 100136486 106569202 106579610 106589989 106590239 106590267 106590268 106590270 106594615
OTW: 112215298 112224716 112226875 112227823 112227824 112227826 112260537
SALP: 111953950 111953951 111972756 111979807 112072575
ELS: 105008681 105009935 105019489 105019511 105019649 105029872 106023710
SFM: 108927716 108930074 108930075 108934018 108934025
PKI: 111835601 111840776 111840835 111859615
LCM: 102349723 102350257(MYH6)
BFO: 118422862
CIN: 100182775
APLC: 110980848
SKO: 100313659
DME: Dmel_CG17927(Mhc)
DER: 6547749
DSE: 6614425
DSI: Dsimw501_GD24080(Dsim_GD24080)
DYA: Dyak_GE12765(Dyak_Mhc)
DAN: 6498172
DSR: 110184857
DPO: Dpse_GA25794
DPE: 6589460
DMN: 108163265
DWI: 6643711
DGR: Dgri_GH11564
DMO: Dmoj_GI17055
DAZ: 108610128
DNV: 108649295
DHE: 111602527
DVI: 6627927
MDE: 101893508
LCQ: 111678371
AGA: AgaP_AGAP010147
AAG: 110678344 5566809 5566990
AALB: 109402113 109412105 109429391 109430926
CQU: CpipJ_CPIJ000848 CpipJ_CPIJ000849 CpipJ_CPIJ000853
AME: 409843
BIM: 100744258
BTER: 100647343
CCAL: 108622790
OBB: 114876930
SOC: 105201286
MPHA: 105835380
AEC: 105144318
ACEP: 105619195
PBAR: 105433414
VEM: 105570649
HST: 105191850
DQU: 106747433
CFO: 105249081
LHU: 105673098
PGC: 109856373
OBO: 105283737
PCF: 106791968 106792815
NVI: 100123633
CSOL: 105368914
MDL: 103577568
TCA: 659358(Mhc1)
DPA: 109544441
ATD: 109598056
NVL: 108560030
BMOR: 100188972
BMAN: 114244973
DPL: KGM_206365
PMAC: 106709212
PRAP: 111001269
HAW: 110379227
TNL: 113498905
PXY: 105388810
API: 100167379
DNX: 107169832
AGS: 114126581
RMD: 113554970
BTAB: 109044765
CLEC: 106664483
PHU: Phum_PHUM098460
ZNE: 110833622
FCD: 110842497 110846404 110849333 110849414 110853473 110853684 110857173 110861366
DPX: DAPPUDRAFT_347733
PVM: 113801120 113801999 113802012 113802013 113802024 113807015 113807016 113807700 113810225 113810227 113810231 113816511 113816514 113816527 113816950 113819191 113819192 113825417 113829966 113829968 113829970 113829972
ISC: IscW_ISCW001340
TUT: 107361059
DPTE: 113794921
CSCU: 111613174 111630771
PTEP: 107443488 107457063
CEL: CELE_F11C3.3(unc-54) CELE_F58G4.1(myo-5) CELE_K12F2.1(myo-3) CELE_R06C7.10(myo-1) CELE_T18D3.4(myo-2)
CBR: CBG00120(Cbr-myo-2) CBG11357(Cbr-myo-5) CBG19730(Cbr-unc-54) CBG21911(Cbr-let-75) CBG23416(Cbr-myo-3)
BMY: Bm1_40715 Bm1_50805 Bm1_51435
LOA: LOAG_16482 LOAG_16751 LOAG_17800
NAI: NECAME_05507 NECAME_07391 NECAME_07589 NECAME_08300
TSP: Tsp_02984 Tsp_08431
LGI: LOTGIDRAFT_223645
PCAN: 112574048
CRG: 105329786 105338907
MYI: 110450619 110459505 110459508
OBI: 106872354(MYH)
LAK: 106168235
SMM: Smp_085540.1
SHX: MS3_05811
OVI: T265_09952
EGL: EGR_03301
NVE: 5516909
EPA: 110239943
ADF: 107352751
AMIL: 114958645
PDAM: 113664641
SPIS: 111324002
DGT: 114528998
HMG: 100205834
AQU: 100631811
 » show all
Reference
PMID:1776652
  Authors
Matsuoka R, Beisel KW, Furutani M, Arai S, Takao A
  Title
Complete sequence of human cardiac alpha-myosin heavy chain gene and amino acid comparison to other myosins based on structural and functional differences.
  Journal
Am J Med Genet 41:537-47 (1991)
DOI:10.1002/ajmg.1320410435
  Sequence
[hsa:4624]
Reference
PMID:2249844
  Authors
Jaenicke T, Diederich KW, Haas W, Schleich J, Lichter P, Pfordt M, Bach A, Vosberg HP
  Title
The complete sequence of the human beta-myosin heavy chain gene and a comparative analysis of its product.
  Journal
Genomics 8:194-206 (1990)
DOI:10.1016/0888-7543(90)90272-v
  Sequence
[hsa:4625]
Reference
  Authors
Berg JS, Powell BC, Cheney RE
  Title
A millennial myosin census.
  Journal
Mol Biol Cell 12:780-94 (2001)
DOI:10.1091/mbc.12.4.780
  Sequence
LinkDB

KEGG   ORTHOLOGY: K10351
Entry
K10351                      KO                                     

Name
MYL2
Definition
myosin regulatory light chain 2
Pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04371  Apelin signaling pathway
ko04510  Focal adhesion
ko04530  Tight junction
ko04670  Leukocyte transendothelial migration
ko04810  Regulation of actin cytoskeleton
ko05131  Shigellosis
ko05132  Salmonella infection
ko05410  Hypertrophic cardiomyopathy
ko05414  Dilated cardiomyopathy
Disease
H00292  Hypertrophic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K10351  MYL2; myosin regulatory light chain 2
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K10351  MYL2; myosin regulatory light chain 2
   04530 Tight junction
    K10351  MYL2; myosin regulatory light chain 2
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K10351  MYL2; myosin regulatory light chain 2
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K10351  MYL2; myosin regulatory light chain 2
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K10351  MYL2; myosin regulatory light chain 2
   04261 Adrenergic signaling in cardiomyocytes
    K10351  MYL2; myosin regulatory light chain 2
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K10351  MYL2; myosin regulatory light chain 2
   05414 Dilated cardiomyopathy
    K10351  MYL2; myosin regulatory light chain 2
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K10351  MYL2; myosin regulatory light chain 2
   05131 Shigellosis
    K10351  MYL2; myosin regulatory light chain 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K10351  MYL2; myosin regulatory light chain 2
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K10351  MYL2; myosin regulatory light chain 2
Genes
HSA: 4633(MYL2)
PTR: 452243(MYL2)
PPS: 100973169(MYL2)
GGO: 101146701(MYL2)
PON: 100462280(MYL2)
NLE: 100590389(MYL2)
MCC: 711937(MYL2)
MCF: 102147025(MYL2)
CSAB: 103239122(MYL2)
RRO: 104674641(MYL2)
RBB: 108512247(MYL2)
CJC: 100408790(MYL2)
SBQ: 101050353(MYL2)
MMU: 17906(Myl2)
MCAL: 110294798(Myl2)
MPAH: 110312960(Myl2)
RNO: 363925(Myl2)
MUN: 110545344(Myl2)
CGE: 100773969(Myl2)
NGI: 103745580(Myl2)
HGL: 101713909(Myl2) 101714346
CCAN: 109685543
OCU: 100353304(MYL2)
TUP: 102502505(MYL2)
CFA: 403614(MYL2)
VVP: 112935243(MYL2)
AML: 100483724(MYL2)
UMR: 103661279(MYL2)
UAH: 113267112(MYL2)
ORO: 101385566(MYL2)
ELK: 111156317
FCA: 101101169(MYL2)
PTG: 102954811(MYL2)
PPAD: 109277655(MYL2)
AJU: 106967527(MYL2)
BTA: 505519(MYL2)
BOM: 102275987(MYL2)
BIU: 109571417(MYL2)
BBUB: 102393988(MYL2)
CHX: 102179873(MYL2)
OAS: 100196904(MYL2)
SSC: 396690(MYL2)
CFR: 102509636(MYL2)
CDK: 105102482(MYL2)
BACU: 103016555(MYL2)
LVE: 103077775(MYL2)
OOR: 101287240(MYL2)
DLE: 111187002(MYL2)
PCAD: 102983557(MYL2)
ECB: 100147688(MYL2)
EPZ: 103544050
EAI: 106842271(MYL2)
MYB: 102258260(MYL2)
MYD: 102754925(MYL2)
MNA: 107529566(MYL2)
HAI: 109386121 109386122
DRO: 112310679 112310708
PALE: 102888244(MYL2)
RAY: 107513248(MYL2)
MJV: 108400560(MYL2)
TMU: 101351770
MDO: 100019715(MYL2)
SHR: 100917142(MYL2)
PCW: 110196868(MYL2)
OAA: 100074559(MYL2)
GGA: 416874(MYL2)
MGP: 100547128(MYL2)
CJO: 107321507(MYL2)
NMEL: 110406487(MYL2)
ACYG: 106031114(MYL2)
TGU: 100223766(MYL2)
LSR: 110478104(MYL2)
SCAN: 103818146(MYL2)
GFR: 102032391(MYL2)
FAB: 101808099(MYL2)
PHI: 102101963(MYL2)
PMAJ: 107211518(MYL2)
CCAE: 111936417(MYL2)
CCW: 104688679(MYL2)
ETL: 114062679(MYL2)
FPG: 101916533(MYL2)
FCH: 102046529(MYL2)
CLV: 102085726 102098030
EGZ: 104122714(MYL2)
NNI: 104019401(MYL2)
ACUN: 113486078(MYL2)
PADL: 103914543(MYL2)
AAM: 106495672(MYL2)
ASN: 102375176(MYL2)
AMJ: 102563829(MYL2)
PSS: 102449621(MYL2)
CMY: 102937866
CPIC: 101931587(MYL2)
ACS: 100566191(myl2)
PVT: 110083871(MYL2)
PBI: 103055734(MYL2)
PMUR: 107286997(MYL2)
TSR: 106548632(MYL2)
PMUA: 114602734(MYL2)
GJA: 107112184(MYL2)
XLA: 108697104 447131(myl2.S)
XTR: 100135705(myl2)
NPR: 108788538(MYL2)
DRE: 100537244(myl2a) 677750(myl2b)
SRX: 107714591 107720970 107743076
SANH: 107670978 107699636 107701848
SGH: 107552143 107553045 107563425 107567947
CCAR: 109049019 109066430 109089231 109095081 109095082
AMEX: 103044021 103047490
EEE: 113571031 113583613
TRU: 101064268 101071916
TNG: GSTEN00021603G001 GSTEN00035940G001
LCO: 104926365 104927948
NCC: 104965458(myl2)
MZE: 101478915 101482094
ONL: 100690118 100699907
OLA: 101155507 101162219
XMA: 102221311 102235799
XCO: 114135493 114155283
PRET: 103464970 103469530
CVG: 107093673 107097276
NFU: 107385499
KMR: 108239856(myl2a)
ALIM: 106518399 106529458
AOCE: 111567162 111577851
CSEM: 103386220 103397433(myl2)
POV: 109629026 109633730
LCF: 108878787 108899709
SDU: 111221531 111226251
SLAL: 111647905 111670903
HCQ: 109522138
BPEC: 110153909
MALB: 109955954 109959694
SASA: 100196342(mlrv) 106583376 106585309
OTW: 112215535 112255301
SALP: 111964589
ELS: 105017044
SFM: 108933343(myl2)
PKI: 111842153(myl2)
LCM: 102362592(MYL2)
CMK: 103184326(myl2)
RTP: 109935120
NVI: 100115182
 » show all
Reference
  Authors
Stevens L, Bastide B, Hedou J, Cieniewski-Bernard C, Montel V, Cochon L, Dupont E, Mounier Y
  Title
Potential regulation of human muscle plasticity by MLC2 post-translational modifications during bed rest and countermeasures.
  Journal
Arch Biochem Biophys 540:125-32 (2013)
DOI:10.1016/j.abb.2013.10.016
Reference
PMID:2704627
  Authors
Dalla Libera L, Hoffmann E, Floroff M, Jackowski G
  Title
Isolation and nucleotide sequence of the cDNA encoding human ventricular myosin light chain 2.
  Journal
Nucleic Acids Res 17:2360 (1989)
DOI:10.1093/nar/17.6.2360
  Sequence
[hsa:4633]
LinkDB

KEGG   ORTHOLOGY: K12749
Entry
K12749                      KO                                     

Name
MYL3
Definition
myosin light chain 3
Pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04371  Apelin signaling pathway
ko05410  Hypertrophic cardiomyopathy
ko05414  Dilated cardiomyopathy
Disease
H00292  Hypertrophic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K12749  MYL3; myosin light chain 3
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K12749  MYL3; myosin light chain 3
   04261 Adrenergic signaling in cardiomyocytes
    K12749  MYL3; myosin light chain 3
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K12749  MYL3; myosin light chain 3
   05414 Dilated cardiomyopathy
    K12749  MYL3; myosin light chain 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12749  MYL3; myosin light chain 3
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12749  MYL3; myosin light chain 3
Genes
HSA: 4634(MYL3)
PTR: 460327(MYL3)
PPS: 100994049(MYL3)
GGO: 101130342(MYL3)
PON: 100174572(MYL3)
NLE: 100583112(MYL3)
MCC: 712209(MYL3)
MCF: 102117313(MYL3)
CSAB: 103227553(MYL3)
RRO: 104671315(MYL3)
RBB: 108517652(MYL3)
CJC: 100402415(MYL3)
SBQ: 101033364(MYL3)
MMU: 17897(Myl3)
MCAL: 110301920(Myl3)
MPAH: 110328443(Myl3)
RNO: 24585(Myl3)
MUN: 110554994(Myl3)
CGE: 100766026(Myl3)
NGI: 103732019(Myl3)
HGL: 101716754(Myl3)
CCAN: 109701071(Myl3)
OCU: 100347740(MYL3)
TUP: 102474564(MYL3)
CFA: 476644(MYL3)
VVP: 112913253(MYL3)
AML: 100466054(MYL3)
UMR: 103675121(MYL3)
UAH: 113256802(MYL3)
ORO: 101363411(MYL3)
ELK: 111143787
FCA: 101084780(MYL3)
PTG: 102953715(MYL3)
PPAD: 109247726(MYL3)
AJU: 106969037(MYL3)
BTA: 618352(MYL3)
BOM: 102264943(MYL3)
BIU: 109576315(MYL3)
BBUB: 102396703(MYL3)
CHX: 102175068(MYL3)
OAS: 101115408(MYL3)
SSC: 100515755(MYL3)
CFR: 102513520(MYL3)
CDK: 105103584(MYL3)
BACU: 102999204(MYL3)
LVE: 103085123(MYL3)
OOR: 101277071(MYL3)
DLE: 111174466(MYL3)
PCAD: 102978650(MYL3)
ECB: 100054327(MYL3)
EPZ: 103551037(MYL3)
EAI: 106823258(MYL3)
MYB: 102258821(MYL3)
MYD: 102768945(MYL3)
MNA: 107529383(MYL3)
HAI: 109375284(MYL3)
DRO: 112309882(MYL3)
PALE: 102892357(MYL3)
RAY: 107509109(MYL3)
MJV: 108396488(MYL3)
LAV: 100656780(MYL3)
TMU: 101342128
MDO: 100018980(MYL3)
SHR: 100932686(MYL3)
PCW: 110217119(MYL3)
OAA: 100080927(MYL3)
GGA: 396067(MYL3)
MGP: 100538682(MYL3)
CJO: 107308825(MYL3)
NMEL: 110394307(MYL3)
APLA: 101804464(MYL3)
ACYG: 106036876(MYL3)
LSR: 110476935(MYL3)
SCAN: 103812673(MYL3)
GFR: 102037456(MYL3)
FAB: 101820982(MYL3)
PHI: 102114016(MYL3)
PMAJ: 107215438(MYL3)
CCAE: 111925574(MYL3)
CCW: 104686379(MYL3)
ETL: 114071430
FPG: 101911020(MYL3)
FCH: 102053884(MYL3)
CLV: 102094328(MYL3)
EGZ: 104127426(MYL3)
NNI: 104021723(MYL3)
ACUN: 113476596(MYL3)
PADL: 103924701(MYL3)
AAM: 106485299(MYL3)
ASN: 102376376(MYL3)
AMJ: 102565509(MYL3)
PSS: 102460214(MYL3)
CMY: 102941102
CPIC: 101942875(MYL3)
ACS: 100557845(myl3)
PVT: 110085110
PBI: 103060920
PMUR: 107286016(MYL3)
TSR: 106540512
PMUA: 114607612(MYL3)
GJA: 107123952
XLA: 398607(myl3.L)
XTR: 394608(myl3)
IPU: 108267096
AMEX: 103034677
TRU: 101061450
TNG: GSTEN00016127G001
LCO: 104917696
NCC: 104942410(myl3)
MZE: 101476377
ONL: 100693213
OLA: 101157250
XMA: 102217899
XCO: 114146921
CVG: 107081728(myl3) 107103051
NFU: 107395748
KMR: 108241640(myl13)
ALIM: 106533199(myl3)
AOCE: 111568623
CSEM: 103396388(myl3)
POV: 109640970
LCF: 108883346(myl3)
SDU: 111230999
SLAL: 111653239
HCQ: 109509331 109521149
BPEC: 110158347
MALB: 109955390
SASA: 100136504(MLEC) 100194663
OTW: 112226781 112260649
SALP: 111956293 111978968
ELS: 105019866
SFM: 108931683
LCM: 102358075(MYL3)
CMK: 103174090
RTP: 109915031
PVM: 113807035
 » show all
Reference
PMID:3417683
  Authors
Kurabayashi M, Komuro I, Tsuchimochi H, Takaku F, Yazaki Y
  Title
Molecular cloning and characterization of human atrial and ventricular myosin alkali light chain cDNA clones.
  Journal
J Biol Chem 263:13930-6 (1988)
  Sequence
[hsa:4634]
LinkDB

KEGG   ORTHOLOGY: K12750
Entry
K12750                      KO                                     

Name
MYL4
Definition
myosin light chain 4
Pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko04371  Apelin signaling pathway
Disease
H00731  Atrial fibrillation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K12750  MYL4; myosin light chain 4
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K12750  MYL4; myosin light chain 4
   04261 Adrenergic signaling in cardiomyocytes
    K12750  MYL4; myosin light chain 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12750  MYL4; myosin light chain 4
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12750  MYL4; myosin light chain 4
Genes
HSA: 4635(MYL4)
PTR: 454814(MYL4)
PPS: 100973937(MYL4)
GGO: 101148883(MYL4)
PON: 100444983(MYL4)
NLE: 100594384(MYL4)
MCC: 717354(MYL4)
MCF: 102143592(MYL4)
CSAB: 103243275(MYL4)
RRO: 104662520(MYL4)
RBB: 108536301(MYL4)
CJC: 100415216(MYL4)
SBQ: 101031337(MYL4)
MMU: 17896(Myl4)
MCAL: 110305335(Myl4)
MPAH: 110332070(Myl4)
RNO: 688228(Myl4)
MUN: 110545657(Myl4)
CGE: 100771007(Myl4)
NGI: 103724764(Myl4)
HGL: 101716492(Myl4)
CCAN: 109696586(Myl4)
OCU: 100345621(MYL4)
TUP: 102475162(MYL4)
CFA: 480490(MYL4)
VVP: 112920591(MYL4)
AML: 100475266(MYL4)
UMR: 103665614(MYL4)
UAH: 113265310(MYL4)
ORO: 101370256(MYL4)
ELK: 111158127
FCA: 100316866(MYL4)
PTG: 102969488(MYL4)
PPAD: 109259741(MYL4)
AJU: 106988849(MYL4)
BTA: 504201(MYL4)
BOM: 102269199(MYL4)
BIU: 109573406(MYL4)
BBUB: 102390547(MYL4)
CHX: 102168763(MYL4)
OAS: 101121691(MYL4)
SSC: 100516998(MYL4)
CFR: 102511774(MYL4)
CDK: 105090430(MYL4)
BACU: 103005624(MYL4)
LVE: 103069828(MYL4)
OOR: 101275610(MYL4)
DLE: 111182587(MYL4)
PCAD: 102988459(MYL4)
ECB: 100054510(MYL4)
EPZ: 103560743(MYL4)
EAI: 106836500(MYL4)
MYB: 102262432(MYL4)
MYD: 102761232(MYL4)
MNA: 107531022(MYL4)
HAI: 109380256(MYL4)
DRO: 112316415(MYL4)
PALE: 102881447(MYL4)
RAY: 107508180(MYL4)
MJV: 108396089(MYL4)
LAV: 100665527(MYL4)
TMU: 101359616
MDO: 100021133(MYL4)
SHR: 100913949(MYL4)
PCW: 110215795(MYL4)
OAA: 100087899(MYL4)
GGA: 396472(MYL4)
MGP: 100543339(MYL4)
CJO: 107325141(MYL4)
NMEL: 110388475(MYL4)
APLA: 101791820(MYL4)
ACYG: 106045949(MYL4)
TGU: 100220758
LSR: 110474821(MYL4)
SCAN: 103821661(MYL4)
GFR: 102031521(MYL4)
FAB: 101816985
PHI: 102113085
PMAJ: 107215266(MYL4)
CCAE: 111939923(MYL4)
CCW: 104698635
ETL: 114066937
FPG: 101923465
FCH: 102047288(MYL4)
EGZ: 104127028(MYL4)
NNI: 104012258(MYL4)
ACUN: 113489241
PADL: 103913877(MYL4)
AAM: 106497421(MYL4)
ASN: 102376762(MYL4)
AMJ: 102571199(MYL4)
PSS: 102453002(MYL4)
CMY: 102931763
CPIC: 101930898(MYL4)
ACS: 100558684(myl4)
PVT: 110082051
PBI: 103059639(MYL4)
PMUR: 107303059(MYL4)
TSR: 106556907(MYL4)
PMUA: 114582326
GJA: 107118448(MYL4)
XLA: 100037107 373844(myl4.L)
XTR: 100124786(myl4)
NPR: 108802637(MYL4)
DRE: 100037358(zgc:163073) 574004(myl4) 64671(cmlc1)
SRX: 107708955 107711693 107727541 107732170 107740645 107754315
SANH: 107653918 107662407 107664608 107694961
SGH: 107557349 107568487 107585102 107598675
CCAR: 109047525 109052177 109087734 109099905
IPU: 108272405(myl4)
PHYP: 113527501 113531068 113543886
AMEX: 103026687 103026881
EEE: 113567933 113587833
TRU: 101063574 101065484
TNG: GSTEN00003411G001 GSTEN00034685G001
LCO: 104931894 109142454
NCC: 104957373
MZE: 101483891(myl4)
ONL: 100694366
OLA: 101156903
XMA: 102226792
XCO: 114149012
PRET: 103460389 103473836
CVG: 107095684
NFU: 107374630
KMR: 108230875
ALIM: 106518216
AOCE: 111568168 111570928 111577474 111577731 111585517
CSEM: 103390188
POV: 109626010
LCF: 108873229(myl4) 108874130
SDU: 111230416 111238509
SLAL: 111649333 111664749
HCQ: 109522893
BPEC: 110160456
MALB: 109960656 109972666
SASA: 100196435(myl4) 106600870
OTW: 112225812 112231011 112233494 112259399
SALP: 111981341
ELS: 105023360(myl4)
SFM: 108924846 108941718
PKI: 111843447 111856076
LCM: 102358220(MYL4)
CMK: 103174141
RTP: 109918399
OBI: 106874269
 » show all
Reference
PMID:2849544
  Authors
Arnold HH, Lohse P, Seidel U, Bober E
  Title
A novel human myosin alkali light chain is developmentally regulated. Expression in fetal cardiac and skeletal muscle and in adult atria.
  Journal
Eur J Biochem 178:53-60 (1988)
DOI:10.1111/j.1432-1033.1988.tb14428.x
  Sequence
[hsa:4635]
LinkDB

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