KEGG   ORTHOLOGY: K17940
Entry
K17940                      KO                                     

Name
pqsH
Definition
2-heptyl-3-hydroxy-4(1H)-quinolone synthase [EC:1.14.13.182]
Pathway
ko00405  Phenazine biosynthesis
ko01110  Biosynthesis of secondary metabolites
ko02024  Quorum sensing
ko02025  Biofilm formation - Pseudomonas aeruginosa
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00405 Phenazine biosynthesis
    K17940  pqsH; 2-heptyl-3-hydroxy-4(1H)-quinolone synthase
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K17940  pqsH; 2-heptyl-3-hydroxy-4(1H)-quinolone synthase
   02025 Biofilm formation - Pseudomonas aeruginosa
    K17940  pqsH; 2-heptyl-3-hydroxy-4(1H)-quinolone synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.182  2-heptyl-3-hydroxy-4(1H)-quinolone synthase
     K17940  pqsH; 2-heptyl-3-hydroxy-4(1H)-quinolone synthase
Other DBs
RN: R10467
COG: COG0654
Genes
PAE: PA2587(pqsH)
PAEV: N297_2666
PAEI: N296_2666
PAU: PA14_30630(pqsH)
PAP: PSPA7_2611
PAG: PLES_26011(pqsH)
PAF: PAM18_2406(pqsH)
PNC: NCGM2_3602(pqsH)
PAEB: NCGM1900_3928(pqsH)
PDK: PADK2_11725
PAEP: PA1S_12675
PAEM: U769_12240
PAEL: T223_13295
PAEU: BN889_02851(pqsH)
PAEG: AI22_21235
PAEC: M802_2663
PAEO: M801_2532
SECH: B18_25370
 » show all
Reference
  Authors
Schertzer JW, Brown SA, Whiteley M
  Title
Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH.
  Journal
Mol Microbiol 77:1527-38 (2010)
DOI:10.1111/j.1365-2958.2010.07303.x
  Sequence
LinkDB

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