KEGG   ORTHOLOGY: K18312
Entry
K18312            Tight     KO                                     

Name
styC
Definition
styrene-oxide isomerase [EC:5.3.99.7]
Pathway
ko00643  Styrene degradation
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00643 Styrene degradation
    K18312  styC; styrene-oxide isomerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.99  Other intramolecular oxidoreductases
    5.3.99.7  styrene-oxide isomerase
     K18312  styC; styrene-oxide isomerase
Other DBs
RN: R10697
GO: 0018846
Genes
PSV: PVLB_26567
Reference
PMID:9603811
  Authors
Panke S, Witholt B, Schmid A, Wubbolts MG
  Title
Towards a biocatalyst for (S)-styrene oxide production: characterization of the styrene degradation pathway of Pseudomonas sp. strain VLB120.
  Journal
Appl Environ Microbiol 64:2032-43 (1998)
DOI:10.1128/AEM.64.6.2032-2043.1998
  Sequence
LinkDB

KEGG   ENZYME: 5.3.99.7
Entry
EC 5.3.99.7                 Enzyme                                 

Name
styrene-oxide isomerase;
SOI
Class
Isomerases;
Intramolecular oxidoreductases;
Other intramolecular oxidoreductases
Sysname
styrene-oxide isomerase (epoxide-cleaving)
Reaction(IUBMB)
styrene oxide = phenylacetaldehyde [RN:R02615]
Reaction(KEGG)
R02615 > R10697
Substrate
styrene oxide [CPD:C02083]
Product
phenylacetaldehyde [CPD:C00601]
Comment
Highly specific.
History
EC 5.3.99.7 created 1992
Pathway
ec00643  Styrene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18312  styrene-oxide isomerase
Genes
PSV: PVLB_26567
Reference
1  [PMID:16348047]
  Authors
Hartmans S, Smits JP, van der Werf MJ, Volkering F, de Bont JA.
  Title
Metabolism of Styrene Oxide and 2-Phenylethanol in the Styrene-Degrading Xanthobacter Strain 124X.
  Journal
Appl Environ Microbiol 55:2850-2855 (1989)
DOI:10.1128/AEM.55.11.2850-2855.1989
Other DBs
ExplorEnz - The Enzyme Database: 5.3.99.7
IUBMB Enzyme Nomenclature: 5.3.99.7
ExPASy - ENZYME nomenclature database: 5.3.99.7
UM-BBD (Biocatalysis/Biodegradation Database): 5.3.99.7
BRENDA, the Enzyme Database: 5.3.99.7
CAS: 124541-89-5
LinkDB

KEGG   REACTION: R10697
Entry
R10697                      Reaction                               

Name
styrene-oxide isomerase (epoxide-cleaving)
Definition
(S)-2-Phenyloxirane <=> Phenylacetaldehyde
Equation
Reaction class
RC00758  C00601_C20782
Enzyme
Pathway
rn00643  Styrene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K18312  styrene-oxide isomerase [EC:5.3.99.7]
LinkDB

DBGET integrated database retrieval system