KEGG   ORTHOLOGY: K18348
Entry
K18348                      KO                                     

Name
vanT
Definition
serine/alanine racemase [EC:5.1.1.18 5.1.1.1]
Pathway
ko01502  Vancomycin resistance
ko02020  Two-component system
Module
M00652  Vancomycin resistance, D-Ala-D-Ser type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18348  vanT; serine/alanine racemase
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18348  vanT; serine/alanine racemase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18348  vanT; serine/alanine racemase
Enzymes [BR:ko01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.1  Acting on amino acids and derivatives
    5.1.1.1  alanine racemase
     K18348  vanT; serine/alanine racemase
    5.1.1.18  serine racemase
     K18348  vanT; serine/alanine racemase
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Ser type
    K18348  vanT; serine/alanine racemase
Other DBs
COG: COG0787
GO: 0030378 0008784
Genes
BBE: BBR47_05890
BFM: BP422_28600
PJD: Pjdr2_5612
PBJ: VN24_01305
PRZ: GZH47_24205
SANS: DK43_03870
ECAS: ECBG_02847
EGA: AL523_09455
VCP: H9L18_13845(vanT)
WVR: IE337_06620
CACE: CACET_c25460(vanTG)
CSO: CLS_04640
HSD: SD1D_0543(vanTG)
ACEL: acsn021_25830(vanTG)
CDF: CD630_16280(vanTG)
PDC: CDIF630_01805(vanTG)
CDC: CD196_1551(vanTG)
CDL: CDR20291_1526(vanTG)
PDF: CD630DERM_16280(vanTG)
OVA: OBV_09480(alr)
ABUT: Ami103574_02985(vanT)
CAD: Curi_c05080(vanT)
EUC: EC1_04130
CIU: G4D55_13015(alr)
ERM: EYR00_02870(vanT)
 » show all
Reference
  Authors
Arias CA, Weisner J, Blackburn JM, Reynolds PE
  Title
Serine and alanine racemase activities of VanT: a protein necessary for vancomycin resistance in Enterococcus gallinarum BM4174.
  Journal
Microbiology 146 ( Pt 7):1727-34 (2000)
DOI:10.1099/00221287-146-7-1727
  Sequence
[ecas:ECBG_02847]
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