KEGG   ORTHOLOGY: K19268
Entry
K19268                      KO                                     

Name
glmE, mutE, mamB
Definition
methylaspartate mutase epsilon subunit [EC:5.4.99.1]
Pathway
ko00630  Glyoxylate and dicarboxylate metabolism
ko00660  C5-Branched dibasic acid metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00740  Methylaspartate cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K19268  glmE, mutE, mamB; methylaspartate mutase epsilon subunit
   00660 C5-Branched dibasic acid metabolism
    K19268  glmE, mutE, mamB; methylaspartate mutase epsilon subunit
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.99  Transferring other groups
    5.4.99.1  methylaspartate mutase
     K19268  glmE, mutE, mamB; methylaspartate mutase epsilon subunit
Other DBs
RN: R00262
GO: 0050097
Genes
ECE: Z0893
ECS: ECs0762
ECF: ECH74115_0830(mutE)
ETW: ECSP_0780
ELX: CDCO157_0742
ECOO: ECRM13514_0751
ECOH: ECRM13516_0698
EOK: G2583_0893(mutE)
ELR: ECO55CA74_04345
ECM: EcSMS35_0750(mutE)
EOC: CE10_0731(mutE)
ELO: EC042_0754(mutE)
EFE: EFER_2377
SDY: SDY_0674
KOX: KOX_14670
KOE: A225_1757
CKO: CKO_02418
CAMA: F384_03290
YEN: YE4042(mutE)
YEY: Y11_31531
YEW: CH47_3689
YET: CH48_1494
YEE: YE5303_38761(mutE)
YAL: AT01_1097
YIN: CH53_312
YRO: CH64_1339
MMK: MU9_1022
GAI: IMCC3135_17395(glmE)
AELL: AELL_1273(gmuE)
AAQI: AAQM_1184(gmuE)
ASUI: ASUIS_1231(gmuE)
AHS: AHALO_1532(gmuE)
AMYT: AMYT_1637(gmuE)
AMAR: AMRN_1555(gmuE)
ACAA: ACAN_1585(gmuE)
APAI: APAC_1387(gmuE)
HBV: ABIV_1443(gmuE)
HEBR: AEBR_1480(gmuE)
PACO: AACT_1414(gmuE)
ARC: ABLL_1388
SMUL: SMUL_1980(glmE)
SHAL: SHALO_1754
SULJ: SJPD1_1761
SUN: SUN_1086
CTC: CTC_02565(mutE)
CTET: BN906_02815(mutE)
CKL: CKL_0302(mutE)
CKR: CKR_0253
CLJ: CLJU_c40620(mutE)
CSQ: CSCA_4327
CACE: CACET_c34420(glmE)
CCOH: SAMEA4530647_2260(mutE)
AMT: Amet_3415
HHW: NCTC503_02398(mutE)
BPRO: PMF13cell1_03216(glmE)
EAC: EAL2_808p05900(glmE)
DSY: DSY3234
DHD: Dhaf_4401
DRM: Dred_2690
PTH: PTH_2420
CTHM: CFE_0618
CHY: CHY_0309(mutE)
TPZ: Tph_c20260(glmE)
TAE: TepiRe1_0119(glmE)
PUF: UFO1_3074
PFT: JBW_01515
MANA: MAMMFC1_00633(glmE)
STED: SPTER_10680(glmE)
MBJ: KQ51_00878(glmE)
RHB: NY08_3253
SFA: Sfla_0985
SBH: SBI_00835
SALS: SLNWT_0920
STRP: F750_5863
SLD: T261_1325
SPRI: SPRI_3471
SRW: TUE45_pSRc_0423(mutE)
SRN: A4G23_02370(mutE)
SMAL: SMALA_8120
SLAU: SLA_0040
SLX: SLAV_09275(mutE)
AOI: AORI_3155
AMYY: YIM_11505(mutE)
AORI: SD37_16090
SAQ: Sare_2952
ACTN: L083_4626
AFS: AFR_18510
CAI: Caci_6323
TDE: TDE2236(glmE)
TPED: TPE_1191(glmE)
FNU: FN1855
PCRE: NCTC12858_01579(mutE)
CPI: Cpin_3405
DTU: Dtur_1345
HAL: VNG_2288G(mamB)
HSL: OE_4206F(mamB)
HMA: rrnAC0685(mamB)
HHI: HAH_1338(mamB)
HMU: Hmuk_2981
HALL: LC1Hm_2318(glmE)
HTU: Htur_1593
NMG: Nmag_3335(mamB)
NAT: NJ7G_3292
SALI: L593_04675
 » show all
Reference
PMID:7880251
  Authors
Zelder O, Beatrix B, Leutbecher U, Buckel W
  Title
Characterization of the coenzyme-B12-dependent glutamate mutase from Clostridium cochlearium produced in Escherichia coli.
  Journal
Eur J Biochem 226:577-85 (1994)
DOI:10.1111/j.1432-1033.1994.tb20083.x
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
  Sequence
[hma:rrnAC0685]
LinkDB

KEGG   ORTHOLOGY: K01846
Entry
K01846                      KO                                     

Name
glmS, mutS, mamA
Definition
methylaspartate mutase sigma subunit [EC:5.4.99.1]
Pathway
ko00630  Glyoxylate and dicarboxylate metabolism
ko00660  C5-Branched dibasic acid metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00740  Methylaspartate cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K01846  glmS, mutS, mamA; methylaspartate mutase sigma subunit
   00660 C5-Branched dibasic acid metabolism
    K01846  glmS, mutS, mamA; methylaspartate mutase sigma subunit
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.99  Transferring other groups
    5.4.99.1  methylaspartate mutase
     K01846  glmS, mutS, mamA; methylaspartate mutase sigma subunit
Other DBs
RN: R00262
COG: COG2185
GO: 0050097
Genes
ECE: Z0895
ECS: ECs0764
ECF: ECH74115_0832(mamA)
ETW: ECSP_0782
ELX: CDCO157_0744
ECOO: ECRM13514_0753
ECOH: ECRM13516_0700
ECG: E2348C_0612
EOK: G2583_0895(mamA)
ELR: ECO55CA74_04355
ECM: EcSMS35_0752(mamA)
EOC: CE10_0733(mamA)
ELO: EC042_0756(mamA)
EFE: EFER_2375
SDY: SDY_0676
KOX: KOX_14680
KOE: A225_1759
CKO: CKO_02416
CAMA: F384_03300
YEN: YE4040(mamA)
YEY: Y11_31551
YEW: CH47_3691(mamA)
YET: CH48_1492(mamA)
YEE: YE5303_38741(mamA)
YAL: AT01_1095(mamA)
YIN: CH53_310(mamA)
YRO: CH64_1337(mamA)
MMK: MU9_1020
GAI: IMCC3135_17400(glmS_1)
AELL: AELL_1274(gmuS)
AAQI: AAQM_1185(gmuS)
ASUI: ASUIS_1232(gmuS)
AHS: AHALO_1531(gmuS)
AMYT: AMYT_1636(gmuS)
AMAR: AMRN_1554(gmuS)
ACAA: ACAN_1584(gmuS)
AMOL: AMOL_1598(gmuS)
APAI: APAC_1388(gmuS)
HBV: ABIV_1442(gmuS)
HEBR: AEBR_1481(gmuS)
PACO: AACT_1415(gmuS)
ARC: ABLL_1389
SMUL: SMUL_1981(mamA)
SHAL: SHALO_1755
SULJ: SJPD1_1762
SUN: SUN_1085
RID: RIdsm_04434(mamA)
CTC: CTC_02568(mutS)
CTET: BN906_02817(mutS_3)
CLJ: CLJU_c40640(mutS4)
CSQ: CSCA_4325
CACE: CACET_c34440(glmS1)
CCOH: SAMEA4530647_2262(mutS_3)
AMT: Amet_3416
HHW: NCTC503_02400(mutS_4)
BPRO: PMF13cell1_03214(glmS_2)
EAC: EAL2_808p05920(mamA)
DSY: DSY3236
DHD: Dhaf_4403
DRM: Dred_2692
PTH: PTH_2419(Sbm)
CTHM: CFE_0616
CHY: CHY_0307(mamA)
TPZ: Tph_c20280(mamA)
TAE: TepiRe1_0117(mamA)
PUF: UFO1_3076
PFT: JBW_01513
MANA: MAMMFC1_00635(mamA)
STED: SPTER_10660(glmS_2)
MBJ: KQ51_00876(mamA)
RHB: NY08_3254
SFA: Sfla_0986
SBH: SBI_00836
SVE: SVEN_6011
SALS: SLNWT_0922
STRP: F750_5862
SLD: T261_1326
SPRI: SPRI_3472
SRW: TUE45_pSRc_0422(TUE45_pSRTUE45c_0422)
SMAL: SMALA_8119
SLAU: SLA_0041
AOI: AORI_3154
AMYY: YIM_11500
AORI: SD37_16085
KAL: KALB_1482
SAQ: Sare_2951
ACTN: L083_4626
AFS: AFR_18515
CAI: Caci_6322
TDE: TDE1023(mamA)
TPI: TREPR_1301(mamA)
TPED: TPE_1063(mamA)
FNU: FN1853
PCRE: NCTC12858_01577(mamA)
PIT: PIN17_0464(mamA)
CPI: Cpin_3405
DTH: DICTH_1232(mamA)
DTU: Dtur_1347
HAL: VNG_2286G(mamA)
HSL: OE_4204F(mamA)
HMA: rrnAC0684(mamA1) rrnAC0984(mamA2)
HHI: HAH_1337(mamA1) HAH_1611(mamA2)
HMU: Hmuk_2980
HALL: LC1Hm_2317(glmS3)
NMG: Nmag_3334(mamA)
SALI: L593_04680
 » show all
LinkDB

KEGG   ENZYME: 5.4.99.1
Entry
EC 5.4.99.1                 Enzyme                                 

Name
methylaspartate mutase;
glutamate mutase;
glutamic mutase;
glutamic isomerase;
glutamic acid mutase;
glutamic acid isomerase;
methylaspartic acid mutase;
beta-methylaspartate-glutamate mutase;
glutamate isomerase
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
L-threo-3-methylaspartate carboxy-aminomethylmutase
Reaction(IUBMB)
L-threo-3-methylaspartate = L-glutamate [RN:R00262]
Reaction(KEGG)
R00262
Substrate
L-threo-3-methylaspartate [CPD:C03618]
Product
L-glutamate [CPD:C00025]
Comment
Requires a cobamide coenzyme.
History
EC 5.4.99.1 created 1961
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec00660  C5-Branched dibasic acid metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K01846  methylaspartate mutase sigma subunit
K19268  methylaspartate mutase epsilon subunit
Genes
ECE: Z0893 Z0895
ECS: ECs0762 ECs0764
ECF: ECH74115_0830(mutE) ECH74115_0832(mamA)
ETW: ECSP_0780 ECSP_0782
ELX: CDCO157_0742 CDCO157_0744
ECOO: ECRM13514_0751 ECRM13514_0753
ECOH: ECRM13516_0698 ECRM13516_0700
ECG: E2348C_0612
EOK: G2583_0893(mutE) G2583_0895(mamA)
ELR: ECO55CA74_04345 ECO55CA74_04355
ECM: EcSMS35_0750(mutE) EcSMS35_0752(mamA)
EOC: CE10_0731(mutE) CE10_0733(mamA)
ELO: EC042_0754(mutE) EC042_0756(mamA)
YEN: YE4040(mamA) YE4042(mutE)
YEW: CH47_3689 CH47_3691(mamA)
YET: CH48_1492(mamA) CH48_1494
YEE: YE5303_38741(mamA) YE5303_38761(mutE)
YAL: AT01_1095(mamA) AT01_1097
YIN: CH53_310(mamA) CH53_312
YRO: CH64_1337(mamA) CH64_1339
GAI: IMCC3135_17395(glmE) IMCC3135_17400(glmS_1)
AELL: AELL_1273(gmuE) AELL_1274(gmuS)
AAQI: AAQM_1184(gmuE) AAQM_1185(gmuS)
ASUI: ASUIS_1231(gmuE) ASUIS_1232(gmuS)
AHS: AHALO_1531(gmuS) AHALO_1532(gmuE)
AMYT: AMYT_1636(gmuS) AMYT_1637(gmuE)
AMAR: AMRN_1554(gmuS) AMRN_1555(gmuE)
ACAA: ACAN_1584(gmuS) ACAN_1585(gmuE)
AMOL: AMOL_1598(gmuS)
APAI: APAC_1387(gmuE) APAC_1388(gmuS)
HBV: ABIV_1442(gmuS) ABIV_1443(gmuE)
HEBR: AEBR_1480(gmuE) AEBR_1481(gmuS)
PACO: AACT_1414(gmuE) AACT_1415(gmuS)
SMUL: SMUL_1980(glmE) SMUL_1981(mamA)
RID: RIdsm_04434(mamA)
CTC: CTC_02565(mutE) CTC_02568(mutS)
CTET: BN906_02815(mutE) BN906_02817(mutS_3)
CKL: CKL_0302(mutE)
CKR: CKR_0253
CLJ: CLJU_c40620(mutE) CLJU_c40640(mutS4)
CACE: CACET_c34420(glmE) CACET_c34440(glmS1)
HHW: NCTC503_02398(mutE) NCTC503_02400(mutS_4)
BPRO: PMF13cell1_03214(glmS_2) PMF13cell1_03216(glmE)
EAC: EAL2_808p05900(glmE) EAL2_808p05920(mamA)
PTH: PTH_2419(Sbm) PTH_2420
CHY: CHY_0307(mamA) CHY_0309(mutE)
TPZ: Tph_c20260(glmE) Tph_c20280(mamA)
TAE: TepiRe1_0117(mamA) TepiRe1_0119(glmE)
MANA: MAMMFC1_00633(glmE) MAMMFC1_00635(mamA)
STED: SPTER_10660(glmS_2) SPTER_10680(glmE)
MBJ: KQ51_00876(mamA) KQ51_00878(glmE)
SVE: SVEN_6011
SRW: TUE45_pSRc_0422(TUE45_pSRTUE45c_0422) TUE45_pSRc_0423(mutE)
AMYY: YIM_11500 YIM_11505(mutE)
KAL: KALB_1482
ACTN: L083_4626
TDE: TDE1023(mamA) TDE2236(glmE)
TPED: TPE_1063(mamA) TPE_1191(glmE)
PCRE: NCTC12858_01577(mamA) NCTC12858_01579(mutE)
CPI: Cpin_3405
HAL: VNG_2286G(mamA) VNG_2288G(mamB)
HSL: OE_4204F(mamA) OE_4206F(mamB)
HMA: rrnAC0684(mamA1) rrnAC0685(mamB) rrnAC0984(mamA2)
HHI: HAH_1337(mamA1) HAH_1338(mamB) HAH_1611(mamA2)
HALL: LC1Hm_2317(glmS3) LC1Hm_2318(glmE)
NMG: Nmag_3334(mamA) Nmag_3335(mamB)
 » show all
Reference
1  [PMID:14245371]
  Authors
BARKER HA, ROOZE V, SUZUKI F, IODICE AA.
  Title
THE GLUTAMATE MUTASE SYSTEM. ASSAYS AND PROPERTIES.
  Journal
J Biol Chem 239:3260-6 (1964)
Reference
2  [PMID:16590408]
  Authors
Weissbach H, Toohey J, Barker HA.
  Title
ISOLATION AND PROPERTIES OF B(12) COENZYMES CONTAINING BENZIMIDAZOLE OR DIMETHYLBENZIMIDAZOLE.
  Journal
Proc Natl Acad Sci U S A 45:521-5 (1959)
DOI:10.1073/pnas.45.4.521
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.1
IUBMB Enzyme Nomenclature: 5.4.99.1
ExPASy - ENZYME nomenclature database: 5.4.99.1
BRENDA, the Enzyme Database: 5.4.99.1
CAS: 9032-97-7
LinkDB

KEGG   REACTION: R00262
Entry
R00262                      Reaction                               

Name
L-threo-3-methylaspartate carboxy-aminomethylmutase
Definition
L-threo-3-Methylaspartate <=> L-Glutamate
Equation
Reaction class
RC01221  C00025_C03618
Enzyme
Pathway
rn00630  Glyoxylate and dicarboxylate metabolism
rn00660  C5-Branched dibasic acid metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00740  Methylaspartate cycle
Orthology
K01846  methylaspartate mutase sigma subunit [EC:5.4.99.1]
K19268  methylaspartate mutase epsilon subunit [EC:5.4.99.1]
Other DBs
RHEA: 12860
LinkDB

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