KEGG   ORTHOLOGY: K19670
Entry
K19670                      KO                                     

Name
phnA
Definition
phosphonoacetate hydrolase [EC:3.11.1.2]
Pathway
ko00440  Phosphonate and phosphinate metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K19670  phnA; phosphonoacetate hydrolase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.11  Acting on carbon-phosphorus bonds
   3.11.1  Acting on carbon-phosphorus bonds (only sub-subclass identified to date)
    3.11.1.2  phosphonoacetate hydrolase
     K19670  phnA; phosphonoacetate hydrolase
Other DBs
RN: R00318
COG: COG1524
GO: 0047400
Genes
CRG: 105331432
SPIS: 111345410
SOD: Sant_0055
LGU: LG3211_2563(phnA)
AVN: Avin_17500
AVL: AvCA_17500
AVD: AvCA6_17500
MARS: A8C75_10790
REH: H16_B0836(phnA) H16_B1948(h16_B1948)
CNC: CNE_2c07990(phnA1) CNE_2c19110(phnA2)
CUH: BJN34_32285
REU: Reut_B3720 Reut_B5876
CTI: RALTA_B0698(phnA) RALTA_B1649
CGD: CR3_4144
COX: E0W60_03290(phnA)
BMA: BMAA0859(phnA)
BMV: BMASAVP1_1762(phnA)
BML: BMA10229_2214(phnA)
BMN: BMA10247_A0900(phnA)
BMAE: DM78_3993(phnA)
BMAI: DM57_09860
BMAF: DM51_4553(phnA)
BMAZ: BM44_4873(phnA)
BMAB: BM45_3775(phnA)
BPS: BPSS0348
BPM: BURPS1710b_A1904(phnA)
BPL: BURPS1106A_A0491(phnA)
BPD: BURPS668_A0588(phnA)
BPSE: BDL_3580(phnA)
BPSM: BBQ_5851(phnA)
BPSU: BBN_3744(phnA)
BPSD: BBX_5418(phnA)
BPZ: BP1026B_II0378
BPQ: BPC006_II0468
BPK: BBK_5560(phnA)
BPSH: DR55_4999(phnA)
BPSA: BBU_5769(phnA)
BPSO: X996_4768(phnA)
BUT: X994_4268(phnA)
BTE: BTH_II2050(phnA-2)
BTQ: BTQ_5330(phnA)
BTJ: BTJ_3982(phnA)
BTZ: BTL_4806(phnA)
BTD: BTI_4382(phnA)
BTV: BTHA_5424(phnA)
BTHE: BTN_4456(phnA)
BTHM: BTRA_4721(phnA)
BTHA: DR62_4570
BTHL: BG87_4787(phnA)
BOK: DM82_4423(phnA)
BOC: BG90_6147(phnA)
BUU: WS70_19235
BVI: Bcep1808_3544
BVE: AK36_3215(phnA)
BUR: Bcep18194_A6493 Bcep18194_B0352
BCN: Bcen_2529 Bcen_3071
BCH: Bcen2424_3142 Bcen2424_5296
BCM: Bcenmc03_3158 Bcenmc03_4972
BCJ: BCAL0450 BCAM2494(phnA)
BCEN: DM39_3244(phnA) DM39_5343(phnA)
BCEW: DM40_3146(phnA)
BCEO: I35_3215 I35_6394(phnA)
BAM: Bamb_3194 Bamb_4657
BAC: BamMC406_3077 BamMC406_5185
BMJ: BMULJ_00095
BMU: Bmul_3134 Bmul_3427
BMK: DM80_1720(phnA) DM80_4810(phnA)
BMUL: NP80_114(phnA) NP80_5122(phnA)
BCT: GEM_0290 GEM_5901
BCED: DM42_1816(phnA) DM42_5480(phnA)
BCEP: APZ15_03720 APZ15_23025
BDL: AK34_3335(phnA)
BPYR: ABD05_05795 ABD05_23085
BCON: NL30_16300 NL30_28870
BUB: BW23_1740(phnA) BW23_3715(phnA)
BDF: WI26_15225 WI26_25290
BLAT: WK25_28320
BTEI: WS51_09425 WS51_26120
BSEM: WJ12_15750 WJ12_32530
BPSL: WS57_01645 WS57_34550
BMEC: WJ16_15940 WJ16_31005
BSTG: WT74_16575 WT74_31355
BSTL: BBJ41_12775 BBJ41_26450
BGL: bglu_2g03940
BGU: KS03_5526(phnA)
BUG: BC1001_5539
BGD: bgla_2g05650
BGO: BM43_4195(phnA) BM43_444(phnA)
BYI: BYI23_D005240
BUK: MYA_3171
BUE: BRPE67_DCDS07040
BUL: BW21_3915(phnA)
BUQ: AC233_30045
BGP: BGL_2c04860(phnA)
BPLA: bpln_2g05410
BUD: AQ610_21330
BUM: AXG89_18175
BUI: AX768_20705 AX768_27950
BXE: Bxe_B1870
BXB: DR64_7180(phnA)
BPH: Bphy_5070
BGE: BC1002_3628 BC1002_6646
BPX: BUPH_05554
BPY: Bphyt_4794
BUZ: AYM40_24085
BFN: OI25_4328(phnA) OI25_4864(phnA)
BCAI: K788_0006027 K788_0008336
PSPW: BJG93_17435
PARA: BTO02_27725
PARB: CJU94_20355(phnA)
PHS: C2L64_27730(phnA) C2L64_33580(phnA)
PTER: C2L65_20770(phnA) C2L65_30160(phnA)
PGP: CUJ91_07045(phnA) CUJ91_26155(phnA)
PCJ: CUJ87_19130(phnA)
PTS: CUJ90_19165(phnA)
PCAF: DSC91_001813
PMEG: FNZ07_09305(phnA)
PPK: U875_20725
PPNO: DA70_13415
PPNM: LV28_17285
PRB: X636_13450
PPUL: RO07_11410
PSPU: NA29_07230
PAPI: SG18_11790
PVE: UC34_03105
POX: MB84_07605
PTX: ABW99_14195
PFG: AB870_14320
PNR: AT302_11255
PAND: DRB87_02880(phnA)
PFIB: PI93_002835(phnA)
PLG: NCTC10937_03430(phnA)
CABA: SBC2_67570(phnA_1) SBC2_80210(phnA_2)
BUO: BRPE64_CCDS06620
BPAR: BN117_3778(phnA)
BBH: BN112_2433(phnA)
BBR: BB1010(phnA)
BBM: BN115_0965(phnA)
BBX: BBS798_0984(phnA)
BOZ: DBV39_15360(phnA)
AAQU: D3M96_18740(phnA)
PIG: EGT29_11350(phnA)
RHG: EXZ61_00860(phnA)
POL: Bpro_3220 Bpro_4692
POS: DT070_07560(phnA)
POO: F7R28_01860(phnA)
VEI: Veis_1096
VPE: Varpa_1737 Varpa_2142
VBO: CKY39_09870(phnA) CKY39_30080(phnA)
VAM: C4F17_27625(phnA) C4F17_29370(phnA)
ADN: Alide_4219
ADK: Alide2_4560
LIM: L103DPR2_01228(phnA)
DIH: G7047_26105(phnA)
DRG: H9K76_21720(phnA)
HEE: hmeg3_09350(phnA)
CFU: CFU_0637(phnA)
CARE: LT85_0694
CPRA: CPter91_0748(phnA) CPter91_4526(phnA)
URU: DSM104443_01235(phnA)
UPL: DSM104440_01165(phnA)
BEBA: BWI17_20735
SCU: SCE1572_15275
MRM: A7982_05269
MCI: Mesci_5290
MOP: Mesop_5913
MAM: Mesau_05387
MESW: A9K65_028935
MESP: C1M53_19320(phnA)
MERD: EB233_26580(phnA)
HOE: IMCC20628_02178
AAK: AA2016_5848
AMIH: CO731_05468(phnA)
PHT: BLM14_26045
SME: SM_b21538(phnA)
SMK: Sinme_4733
SMQ: SinmeB_3692
SMX: SM11_pD0622
SMI: BN406_05686(phnA)
SMEG: C770_GR4pD0607
SMEL: SM2011_b21538(phnA)
SMER: DU99_28545
SMD: Smed_4875
SIX: BSY16_5628(phnA)
EAH: FA04_31245
EMX: FKV68_16760(phnA)
AVI: Avi_9252
SHZ: shn_14570 shn_17315
AOL: S58_09400
BRK: CWS35_18315(phnA) CWS35_21300(phnA)
RPA: RPA3737
RPC: RPC_2339
RPT: Rpal_4258
OCA: OCAR_6851(phnA)
OCG: OCA5_c12270
OCO: OCA4_c12270
BOP: AXW83_08860
BOS: BSY19_940
BVV: BHK69_06145
BOI: BLM15_05125 BLM15_17275
BOF: FQV39_06790
STAR: G3545_02510(phnA)
APRA: G3A50_07905(phnA)
CHEL: AL346_10075
DEA: FPZ08_14935(phnA)
PSIN: CAK95_11570
NOH: G5V57_22795(phnA)
RUA: D1823_18760(phnA)
RUT: FIU92_18145(phnA)
PZH: CX676_16685(phnA)
PLIA: E4191_05970(phnA)
LMD: METH_22745
LAQU: R2C4_02150(phnA)
HAT: RC74_13420
DAA: AKL17_3749
SULI: C1J05_07705(phnA)
ROM: EI983_15765(phnA)
SEDI: EBB79_05345(phnA)
PAED: G5B38_01295(phnA) G5B38_14160(phnA)
THAS: C6Y53_07950(phnA)
SMAG: AN936_06190
SMAZ: LH19_15825
SPHX: E5675_16840
SHUM: STHU_12460
SVC: STVA_36690(phnA)
HTQ: FRZ44_32160(phnA)
HADH: FRZ61_15490(phnA)
PEL: SAR11G3_00179
APC: HIMB59_00004470
PSTG: E8M01_18205(phnA) E8M01_19125(phnA) E8M01_31375(phnA)
CBE: Cbei_3507
CBZ: Cbs_3507
CBEI: LF65_03952
CDY: F3K33_17780
PED: ING2D1G_1557
MEG: DKB62_09155
MGO: AFA91_28195
MLL: B1R94_12005
RHW: BFN03_00275 BFN03_19650
RHS: A3Q41_02879(phnA)
DIT: C3V38_14300
DPC: A6048_08745
DLU: A6035_08305
SALU: DC74_7218
SALL: SAZ_37420
SVT: SVTN_38865
ARY: ATC04_16335
LMOI: VV02_16600 VV02_16745
NOY: EXE57_08285
FRE: Franean1_0937
FRI: FraEuI1c_0768
FAL: FRAAL6035
FSY: FsymDg_0922
TRO: trd_1148
KBS: EPA93_07555
LUO: HHL09_10175(phnA)
SDYN: Mal52_16190(phnA)
GMS: SOIL9_67960
SUS: Acid_4377
PCM: AY601_2826
PSTY: BFS30_02930
PGS: CPT03_11840(phnA)
MUH: HYN43_024620
MGK: FSB76_03615
MRUB: DEO27_027060
SBX: CA265_07365
FPSZ: AMR72_12790
AALG: AREALGSMS7_02093(phnA)
AG: AAC15507(phnA)
 » show all
Reference
PMID:8529644
  Authors
McGrath JW, Wisdom GB, McMullan G, Larkin MJ, Quinn JP
  Title
The purification and properties of phosphonoacetate hydrolase, a novel carbon-phosphorus bond-cleavage enzyme from Pseudomonas fluorescens 23F.
  Journal
Eur J Biochem 234:225-30 (1995)
DOI:10.1111/j.1432-1033.1995.225_c.x
  Sequence
LinkDB

KEGG   ENZYME: 3.11.1.2
Entry
EC 3.11.1.2                 Enzyme                                 

Name
phosphonoacetate hydrolase
Class
Hydrolases;
Acting on carbon-phosphorus bonds;
Acting on carbon-phosphorus bonds (only sub-subclass identified to date)
Sysname
phosphonoacetate phosphonohydrolase
Reaction(IUBMB)
phosphonoacetate + H2O = acetate + phosphate [RN:R00318]
Reaction(KEGG)
R00318
Substrate
phosphonoacetate [CPD:C05682];
H2O [CPD:C00001]
Product
acetate [CPD:C00033];
phosphate [CPD:C00009]
Comment
A zinc-dependent enzyme. Belongs to the alkaline phosphatase superfamily of zinc-dependent hydrolases.
History
EC 3.11.1.2 created 1999
Pathway
ec00440  Phosphonate and phosphinate metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K19670  phosphonoacetate hydrolase
Genes
CRG: 105331432
SPIS: 111345410
SOD: Sant_0055
LGU: LG3211_2563(phnA)
AVN: Avin_17500
AVL: AvCA_17500
AVD: AvCA6_17500
MARS: A8C75_10790
REH: H16_B0836(phnA) H16_B1948(h16_B1948)
CNC: CNE_2c07990(phnA1) CNE_2c19110(phnA2)
CUH: BJN34_32285
REU: Reut_B3720 Reut_B5876
CTI: RALTA_B0698(phnA) RALTA_B1649
CGD: CR3_4144
COX: E0W60_03290(phnA)
BMA: BMAA0859(phnA)
BMV: BMASAVP1_1762(phnA)
BML: BMA10229_2214(phnA)
BMN: BMA10247_A0900(phnA)
BMAE: DM78_3993(phnA)
BMAI: DM57_09860
BMAF: DM51_4553(phnA)
BMAZ: BM44_4873(phnA)
BMAB: BM45_3775(phnA)
BPS: BPSS0348
BPM: BURPS1710b_A1904(phnA)
BPL: BURPS1106A_A0491(phnA)
BPD: BURPS668_A0588(phnA)
BPSE: BDL_3580(phnA)
BPSM: BBQ_5851(phnA)
BPSU: BBN_3744(phnA)
BPSD: BBX_5418(phnA)
BPZ: BP1026B_II0378
BPQ: BPC006_II0468
BPK: BBK_5560(phnA)
BPSH: DR55_4999(phnA)
BPSA: BBU_5769(phnA)
BPSO: X996_4768(phnA)
BUT: X994_4268(phnA)
BTE: BTH_II2050(phnA-2)
BTQ: BTQ_5330(phnA)
BTJ: BTJ_3982(phnA)
BTZ: BTL_4806(phnA)
BTD: BTI_4382(phnA)
BTV: BTHA_5424(phnA)
BTHE: BTN_4456(phnA)
BTHM: BTRA_4721(phnA)
BTHA: DR62_4570
BTHL: BG87_4787(phnA)
BOK: DM82_4423(phnA)
BOC: BG90_6147(phnA)
BUU: WS70_19235
BVI: Bcep1808_3544
BVE: AK36_3215(phnA)
BUR: Bcep18194_A6493 Bcep18194_B0352
BCN: Bcen_2529 Bcen_3071
BCH: Bcen2424_3142 Bcen2424_5296
BCM: Bcenmc03_3158 Bcenmc03_4972
BCJ: BCAL0450 BCAM2494(phnA)
BCEN: DM39_3244(phnA) DM39_5343(phnA)
BCEW: DM40_3146(phnA)
BCEO: I35_3215 I35_6394(phnA)
BAM: Bamb_3194 Bamb_4657
BAC: BamMC406_3077 BamMC406_5185
BMJ: BMULJ_00095
BMU: Bmul_3134 Bmul_3427
BMK: DM80_1720(phnA) DM80_4810(phnA)
BMUL: NP80_114(phnA) NP80_5122(phnA)
BCT: GEM_0290 GEM_5901
BCED: DM42_1816(phnA) DM42_5480(phnA)
BCEP: APZ15_03720 APZ15_23025
BDL: AK34_3335(phnA)
BPYR: ABD05_05795 ABD05_23085
BCON: NL30_16300 NL30_28870
BUB: BW23_1740(phnA) BW23_3715(phnA)
BDF: WI26_15225 WI26_25290
BLAT: WK25_28320
BTEI: WS51_09425 WS51_26120
BSEM: WJ12_15750 WJ12_32530
BPSL: WS57_01645 WS57_34550
BMEC: WJ16_15940 WJ16_31005
BSTG: WT74_16575 WT74_31355
BSTL: BBJ41_12775 BBJ41_26450
BGL: bglu_2g03940
BGU: KS03_5526(phnA)
BUG: BC1001_5539
BGD: bgla_2g05650
BGO: BM43_4195(phnA) BM43_444(phnA)
BYI: BYI23_D005240
BUK: MYA_3171
BUE: BRPE67_DCDS07040
BUL: BW21_3915(phnA)
BUQ: AC233_30045
BGP: BGL_2c04860(phnA)
BPLA: bpln_2g05410
BUD: AQ610_21330
BUM: AXG89_18175
BUI: AX768_20705 AX768_27950
BXE: Bxe_B1870
BXB: DR64_7180(phnA)
BPH: Bphy_5070
BGE: BC1002_3628 BC1002_6646
BPX: BUPH_05554
BPY: Bphyt_4794
BUZ: AYM40_24085
BFN: OI25_4328(phnA) OI25_4864(phnA)
BCAI: K788_0006027 K788_0008336
PSPW: BJG93_17435
PARA: BTO02_27725
PARB: CJU94_20355(phnA)
PHS: C2L64_27730(phnA) C2L64_33580(phnA)
PTER: C2L65_20770(phnA) C2L65_30160(phnA)
PGP: CUJ91_07045(phnA) CUJ91_26155(phnA)
PCJ: CUJ87_19130(phnA)
PTS: CUJ90_19165(phnA)
PCAF: DSC91_001813
PMEG: FNZ07_09305(phnA)
PPK: U875_20725
PPNO: DA70_13415
PPNM: LV28_17285
PRB: X636_13450
PPUL: RO07_11410
PSPU: NA29_07230
PAPI: SG18_11790
PVE: UC34_03105
POX: MB84_07605
PTX: ABW99_14195
PFG: AB870_14320
PNR: AT302_11255
PAND: DRB87_02880(phnA)
PFIB: PI93_002835(phnA)
PLG: NCTC10937_03430(phnA)
CABA: SBC2_67570(phnA_1) SBC2_80210(phnA_2)
BUO: BRPE64_CCDS06620
BPAR: BN117_3778(phnA)
BBH: BN112_2433(phnA)
BBR: BB1010(phnA)
BBM: BN115_0965(phnA)
BBX: BBS798_0984(phnA)
BOZ: DBV39_15360(phnA)
AAQU: D3M96_18740(phnA)
PIG: EGT29_11350(phnA)
RHG: EXZ61_00860(phnA)
POL: Bpro_3220 Bpro_4692
POS: DT070_07560(phnA)
POO: F7R28_01860(phnA)
VEI: Veis_1096
VPE: Varpa_1737 Varpa_2142
VBO: CKY39_09870(phnA) CKY39_30080(phnA)
VAM: C4F17_27625(phnA) C4F17_29370(phnA)
ADN: Alide_4219
ADK: Alide2_4560
LIM: L103DPR2_01228(phnA)
DIH: G7047_26105(phnA)
DRG: H9K76_21720(phnA)
HEE: hmeg3_09350(phnA)
CFU: CFU_0637(phnA)
CARE: LT85_0694
CPRA: CPter91_0748(phnA) CPter91_4526(phnA)
URU: DSM104443_01235(phnA)
UPL: DSM104440_01165(phnA)
BEBA: BWI17_20735
SCU: SCE1572_15275
MRM: A7982_05269
MCI: Mesci_5290
MOP: Mesop_5913
MAM: Mesau_05387
MESW: A9K65_028935
MESP: C1M53_19320(phnA)
MERD: EB233_26580(phnA)
HOE: IMCC20628_02178
AAK: AA2016_5848
AMIH: CO731_05468(phnA)
PHT: BLM14_26045
SME: SM_b21538(phnA)
SMK: Sinme_4733
SMQ: SinmeB_3692
SMX: SM11_pD0622
SMI: BN406_05686(phnA)
SMEG: C770_GR4pD0607
SMEL: SM2011_b21538(phnA)
SMER: DU99_28545
SMD: Smed_4875
SIX: BSY16_5628(phnA)
EAH: FA04_31245
EMX: FKV68_16760(phnA)
AVI: Avi_9252
SHZ: shn_14570 shn_17315
AOL: S58_09400
BRK: CWS35_18315(phnA) CWS35_21300(phnA)
RPA: RPA3737
RPC: RPC_2339
RPT: Rpal_4258
OCA: OCAR_6851(phnA)
OCG: OCA5_c12270
OCO: OCA4_c12270
BOP: AXW83_08860
BOS: BSY19_940
BVV: BHK69_06145
BOI: BLM15_05125 BLM15_17275
BOF: FQV39_06790
STAR: G3545_02510(phnA)
APRA: G3A50_07905(phnA)
CHEL: AL346_10075
DEA: FPZ08_14935(phnA)
PSIN: CAK95_11570
NOH: G5V57_22795(phnA)
RUA: D1823_18760(phnA)
RUT: FIU92_18145(phnA)
PZH: CX676_16685(phnA)
PLIA: E4191_05970(phnA)
LMD: METH_22745
LAQU: R2C4_02150(phnA)
HAT: RC74_13420
DAA: AKL17_3749
SULI: C1J05_07705(phnA)
ROM: EI983_15765(phnA)
SEDI: EBB79_05345(phnA)
PAED: G5B38_01295(phnA) G5B38_14160(phnA)
THAS: C6Y53_07950(phnA)
SMAG: AN936_06190
SMAZ: LH19_15825
SPHX: E5675_16840
SHUM: STHU_12460
SVC: STVA_36690(phnA)
HTQ: FRZ44_32160(phnA)
HADH: FRZ61_15490(phnA)
PEL: SAR11G3_00179
APC: HIMB59_00004470
PSTG: E8M01_18205(phnA) E8M01_19125(phnA) E8M01_31375(phnA)
CBE: Cbei_3507
CBZ: Cbs_3507
CBEI: LF65_03952
CDY: F3K33_17780
PED: ING2D1G_1557
MEG: DKB62_09155
MGO: AFA91_28195
MLL: B1R94_12005
RHW: BFN03_00275 BFN03_19650
RHS: A3Q41_02879(phnA)
DIT: C3V38_14300
DPC: A6048_08745
DLU: A6035_08305
SALU: DC74_7218
SALL: SAZ_37420
SVT: SVTN_38865
ARY: ATC04_16335
LMOI: VV02_16600 VV02_16745
NOY: EXE57_08285
FRE: Franean1_0937
FRI: FraEuI1c_0768
FAL: FRAAL6035
FSY: FsymDg_0922
TRO: trd_1148
KBS: EPA93_07555
LUO: HHL09_10175(phnA)
SDYN: Mal52_16190(phnA)
GMS: SOIL9_67960
SUS: Acid_4377
PCM: AY601_2826
PSTY: BFS30_02930
PGS: CPT03_11840(phnA)
MUH: HYN43_024620
MGK: FSB76_03615
MRUB: DEO27_027060
SBX: CA265_07365
FPSZ: AMR72_12790
AALG: AREALGSMS7_02093(phnA)
 » show all
Reference
1  [PMID:8529644]
  Authors
McGrath JW, Wisdom GB, McMullan G, Larkin MJ, Quinn JP
  Title
The purification and properties of phosphonoacetate hydrolase, a novel carbon-phosphorus bond-cleavage enzyme from Pseudomonas fluorescens 23F.
  Journal
Eur J Biochem 234:225-30 (1995)
DOI:10.1111/j.1432-1033.1995.225_c.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.11.1.2
IUBMB Enzyme Nomenclature: 3.11.1.2
ExPASy - ENZYME nomenclature database: 3.11.1.2
BRENDA, the Enzyme Database: 3.11.1.2
CAS: 153570-68-4
LinkDB

KEGG   REACTION: R00318
Entry
R00318                      Reaction                               

Name
Phosphonoacetate phosphonohydrolase
Definition
Phosphonoacetate + H2O <=> Acetate + Orthophosphate
Equation
Reaction class
RC01309  C00033_C05682
Enzyme
Pathway
rn00440  Phosphonate and phosphinate metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K19670  phosphonoacetate hydrolase [EC:3.11.1.2]
Other DBs
RHEA: 16752
LinkDB

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