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Entry
K19853                      KO                                     

Name
tyl1a
Definition
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase [EC:5.3.2.4]
Pathway
ko00523  Polyketide sugar unit biosynthesis
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00796  dTDP-D-mycaminose biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K19853  tyl1a; TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.2  Interconverting keto- and enol-groups
    5.3.2.4  TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming)
     K19853  tyl1a; TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase
BRITE hierarchy
Other DBs
RN: R06424
Genes
SAMB: SAM23877_5623(srm14)
TaxonomyKoalaUniProt
Reference
  Authors
Melancon CE 3rd, Hong L, White JA, Liu YN, Liu HW
  Title
Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and substrate specificity studies.
  Journal
Biochemistry 46:577-90 (2007)
DOI:10.1021/bi061907y
Reference
  Authors
Karray F, Darbon E, Oestreicher N, Dominguez H, Tuphile K, Gagnat J, Blondelet-Rouault MH, Gerbaud C, Pernodet JL
  Title
Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.
  Journal
Microbiology 153:4111-22 (2007)
DOI:10.1099/mic.0.2007/009746-0
  Sequence
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