KEGG   ORTHOLOGY: K19854
Entry
K19854                      KO                                     

Name
tylB
Definition
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase [EC:2.6.1.89]
Pathway
ko00523  Polyketide sugar unit biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00796  dTDP-D-mycaminose biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K19854  tylB; dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.89  dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase
     K19854  tylB; dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase
Other DBs
RN: R06423
Genes
SAMB: SAM23877_5622(srm15)
AG: AAA21342(tylB)
Reference
  Authors
Melancon CE 3rd, Hong L, White JA, Liu YN, Liu HW
  Title
Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and substrate specificity studies.
  Journal
Biochemistry 46:577-90 (2007)
DOI:10.1021/bi061907y
Reference
  Authors
Karray F, Darbon E, Oestreicher N, Dominguez H, Tuphile K, Gagnat J, Blondelet-Rouault MH, Gerbaud C, Pernodet JL
  Title
Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens.
  Journal
Microbiology 153:4111-22 (2007)
DOI:10.1099/mic.0.2007/009746-0
  Sequence
Reference
PMID:7984112
  Authors
Merson-Davies LA, Cundliffe E
  Title
Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome.
  Journal
Mol Microbiol 13:349-55 (1994)
DOI:10.1111/j.1365-2958.1994.tb00428.x
  Sequence
LinkDB

DBGET integrated database retrieval system