KEGG   ORTHOLOGY: K20170
Entry
K20170                      KO                                     

Name
nicA1
Definition
nicotine oxidoreductase [EC:1.5.3.-]
Pathway
ko00760  Nicotinate and nicotinamide metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K20170  nicA1; nicotine oxidoreductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.3  With oxygen as acceptor
    1.5.3.-  
     K20170  nicA1; nicotine oxidoreductase
Other DBs
RN: R11175 R11177 R11178
COG: COG3344
Genes
PPT: PPS_0381
PSTU: UIB01_18630
Reference
  Authors
Tang H, Wang L, Wang W, Yu H, Zhang K, Yao Y, Xu P
  Title
Systematic unraveling of the unsolved pathway of nicotine degradation in Pseudomonas.
  Journal
PLoS Genet 9:e1003923 (2013)
DOI:10.1371/journal.pgen.1003923
  Sequence
[ppt:PPS_0381]
LinkDB

KEGG   ORTHOLOGY: K20169
Entry
K20169                      KO                                     

Name
nox, nicA2
Definition
nicotine oxidoreductase [EC:1.5.3.-]
Pathway
ko00760  Nicotinate and nicotinamide metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K20169  nox, nicA2; nicotine oxidoreductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.3  With oxygen as acceptor
    1.5.3.-  
     K20169  nox, nicA2; nicotine oxidoreductase
Other DBs
RN: R11175 R11177
COG: COG1231
Genes
PPT: PPS_4081
PMON: X969_19995
PMOT: X970_19630
AG: AGH68979(nox)
Reference
  Authors
Qiu J, Ma Y, Wen Y, Chen L, Wu L, Liu W
  Title
Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine.
  Journal
Appl Environ Microbiol 78:2154-60 (2012)
DOI:10.1128/AEM.07025-11
Reference
  Authors
Qiu J, Ma Y, Zhang J, Wen Y, Liu W
  Title
Cloning of a novel nicotine oxidase gene from Pseudomonas sp. strain HZN6 whose product nonenantioselectively degrades nicotine to pseudooxynicotine.
  Journal
Appl Environ Microbiol 79:2164-71 (2013)
DOI:10.1128/AEM.03824-12
  Sequence
Reference
  Authors
Tang H, Wang L, Wang W, Yu H, Zhang K, Yao Y, Xu P
  Title
Systematic unraveling of the unsolved pathway of nicotine degradation in Pseudomonas.
  Journal
PLoS Genet 9:e1003923 (2013)
DOI:10.1371/journal.pgen.1003923
  Sequence
[ppt:PPS_4081]
LinkDB

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