KEGG   ORTHOLOGY: K20431
Entry
K20431                      KO                                     

Name
cetB, valD
Definition
2-epi-5-epi-valiolone epimerase [EC:5.1.3.33]
Pathway
ko00525  Acarbose and validamycin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00815  Validamycin A biosynthesis, sedoheptulopyranose-7P => validamycin A
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00525 Acarbose and validamycin biosynthesis
    K20431  cetB, valD; 2-epi-5-epi-valiolone epimerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.3  Acting on carbohydrates and derivatives
    5.1.3.33  2-epi-5-epi-valiolone epimerase
     K20431  cetB, valD; 2-epi-5-epi-valiolone epimerase
Other DBs
RN: R11079
COG: COG0346
Genes
SHY: SHJG_0279
SHO: SHJGH_0113
MCAB: HXZ27_14360
AG: ABL74382(cetB)
Reference
  Authors
Xu H, Zhang Y, Yang J, Mahmud T, Bai L, Deng Z
  Title
Alternative epimerization in C(7)N-aminocyclitol biosynthesis is catalyzed by ValD, a large protein of the vicinal oxygen chelate superfamily.
  Journal
Chem Biol 16:567-76 (2009)
DOI:10.1016/j.chembiol.2009.04.006
  Sequence
[shy:SHJG_0279]
Reference
  Authors
Wu X, Flatt PM, Xu H, Mahmud T
  Title
Biosynthetic gene cluster of cetoniacytone A, an unusual aminocyclitol from the endosymbiotic Bacterium Actinomyces sp. Lu 9419.
  Journal
Chembiochem 10:304-14 (2009)
DOI:10.1002/cbic.200800527
  Sequence
LinkDB

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