KEGG   ORTHOLOGY: K20432
Entry
K20432                      KO                                     

Name
valK
Definition
5-epi-valiolone dehydratase [EC:4.2.1.-]
Pathway
ko00525  Acarbose and validamycin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00815  Validamycin A biosynthesis, sedoheptulopyranose-7P => validamycin A
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00525 Acarbose and validamycin biosynthesis
    K20432  valK; 5-epi-valiolone dehydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.-  
     K20432  valK; 5-epi-valiolone dehydratase
Other DBs
RN: R11233
COG: COG0702
Genes
SUR: STAUR_3138(valK)
SHY: SHJG_0275
SHO: SHJGH_0109
SGU: SGLAU_01050(gacO)
AMI: Amir_1998
Reference
  Authors
Bai L, Li L, Xu H, Minagawa K, Yu Y, Zhang Y, Zhou X, Floss HG, Mahmud T, Deng Z
  Title
Functional analysis of the validamycin biosynthetic gene cluster and engineered production of validoxylamine A.
  Journal
Chem Biol 13:387-97 (2006)
DOI:10.1016/j.chembiol.2006.02.002
  Sequence
[shy:SHJG_0275]
Reference
  Authors
Cui L, Zhu Y, Guan X, Deng Z, Bai L, Feng Y
  Title
De Novo Biosynthesis of beta-Valienamine in Engineered Streptomyces hygroscopicus 5008.
  Journal
ACS Synth Biol 5:15-20 (2016)
DOI:10.1021/acssynbio.5b00138
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