KEGG   ORTHOLOGY: K21224
Entry
K21224                      KO                                     

Name
kedN5
Definition
radical SAM C-methyltransferase
Pathway
ko01059  Biosynthesis of enediyne antibiotics
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00831  Kedarcidin 2-hydroxynaphthoate moiety biosynthesis, malonyl-CoA => 3,6,8-trihydroxy-2-naphthoate => 3-hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21224  kedN5; radical SAM C-methyltransferase
Other DBs
RN: R11389
COG: COG1032
Genes
SGR: SGR_913
SNK: CP967_12565
SESP: BN6_45930
KPHY: AOZ06_30985
AHM: TL08_15140
SAQ: Sare_2941
MAU: Micau_3868
MIL: ML5_4549
PSUU: Psuf_000750
AG: AFV52163(kedN5)
Reference
  Authors
Lohman JR, Huang SX, Horsman GP, Dilfer PE, Huang T, Chen Y, Wendt-Pienkowski E, Shen B
  Title
Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.
  Journal
Mol Biosyst 9:478-91 (2013)
DOI:10.1039/c3mb25523a
  Sequence
LinkDB

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