KEGG   ORTHOLOGY: K21260
Entry
K21260                      KO                                     

Name
calG2
Definition
calicheamicin 4-deoxy-4-thio-alpha-D-digitoxosyltransferase [EC:2.4.1.-]
Pathway
ko01059  Biosynthesis of enediyne antibiotics
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00833  Calicheamicin biosynthesis, calicheamicinone => calicheamicin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    K21260  calG2; calicheamicin 4-deoxy-4-thio-alpha-D-digitoxosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.-  
     K21260  calG2; calicheamicin 4-deoxy-4-thio-alpha-D-digitoxosyltransferase
Other DBs
RN: R11418
COG: COG1819
CAZy: GT1
Genes
SAQ: Sare_2036
AG: AAM70348(calG2)
Reference
  Authors
Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS
  Title
The calicheamicin gene cluster and its iterative type I enediyne PKS.
  Journal
Science 297:1173-6 (2002)
DOI:10.1126/science.1072105
  Sequence
Reference
  Authors
Zhang C, Bitto E, Goff RD, Singh S, Bingman CA, Griffith BR, Albermann C, Phillips GN Jr, Thorson JS
  Title
Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis.
  Journal
Chem Biol 15:842-53 (2008)
DOI:10.1016/j.chembiol.2008.06.011
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