KEGG   ORTHOLOGY: K21539
Entry
K21539            Tight     KO                                     
Symbol
mycF
Name
mycinamicin III 3''-O-methyltransferase [EC:2.1.1.237]
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00934  Mycinamicin biosynthesis, malonyl-CoA + methylmalonyl-CoA => protomycinolide IV => mycinamicin II
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K21539  mycF; mycinamicin III 3''-O-methyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K21539  mycF; mycinamicin III 3''-O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.237  mycinamicin III 3''-O-methyltransferase
     K21539  mycF; mycinamicin III 3''-O-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Methylase
   K21539  mycF; mycinamicin III 3''-O-methyltransferase
Other DBs
RN: R09823
Genes
AG: BAA03670(mycF)
Reference
  Authors
Li S, Anzai Y, Kinoshita K, Kato F, Sherman DH
  Title
Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics.
  Journal
Chembiochem 10:1297-301 (2009)
DOI:10.1002/cbic.200900088
  Sequence
LinkDB

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