KEGG   ORTHOLOGY: K21946
Entry
K21946                      KO                                     

Name
DUSP6
Definition
dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
Pathway
ko04010  MAPK signaling pathway
ko05202  Transcriptional misregulation in cancer
ko05221  Acute myeloid leukemia
Disease
H00255  Hypogonadotropic hypogonadism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K21946  DUSP6; dual specificity phosphatase 6
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K21946  DUSP6; dual specificity phosphatase 6
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    K21946  DUSP6; dual specificity phosphatase 6
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K21946  DUSP6; dual specificity phosphatase 6
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K21946  DUSP6; dual specificity phosphatase 6
    3.1.3.48  protein-tyrosine-phosphatase
     K21946  DUSP6; dual specificity phosphatase 6
Protein phosphatases and associated proteins [BR:ko01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    K21946  DUSP6; dual specificity phosphatase 6
Other DBs
GO: 0017017 0004725
Genes
HSA: 1848(DUSP6)
PTR: 452115(DUSP6)
PPS: 100974933(DUSP6)
GGO: 101127326(DUSP6)
PON: 100460800(DUSP6)
NLE: 100588912(DUSP6)
MCC: 708907(DUSP6)
MCF: 101926722(DUSP6)
CSAB: 103238831(DUSP6)
RRO: 104662546(DUSP6)
RBB: 108524461(DUSP6)
CJC: 100409879(DUSP6)
SBQ: 101048106(DUSP6)
MMU: 67603(Dusp6)
MCAL: 110303747(Dusp6)
MPAH: 110326343(Dusp6)
RNO: 116663(Dusp6)
MUN: 110552128(Dusp6)
CGE: 100764365(Dusp6)
NGI: 103726469(Dusp6)
HGL: 101697963(Dusp6)
CCAN: 109696668(Dusp6)
OCU: 100355690(DUSP6)
TUP: 102503417(DUSP6)
CFA: 482594(DUSP6)
VVP: 112914896(DUSP6)
AML: 100466694(DUSP6)
UMR: 103660145(DUSP6)
UAH: 113256188(DUSP6)
ORO: 101378028(DUSP6)
ELK: 111142278
FCA: 101097255(DUSP6)
PTG: 102949309(DUSP6)
PPAD: 109265302(DUSP6)
AJU: 106976657(DUSP6)
BTA: 515310(DUSP6)
BOM: 102282587(DUSP6)
BIU: 109558960(DUSP6)
BBUB: 102391799(DUSP6)
CHX: 102172327(DUSP6)
OAS: 101110315(DUSP6)
SSC: 100622968(DUSP6)
CFR: 102513995(DUSP6)
CDK: 105094865(DUSP6)
BACU: 103001134(DUSP6)
LVE: 103079648(DUSP6)
OOR: 101278296(DUSP6)
DLE: 111163578(DUSP6)
PCAD: 102989050(DUSP6)
ECB: 100051565(DUSP6)
EPZ: 103547849(DUSP6)
EAI: 106845652(DUSP6)
MYB: 102259806(DUSP6)
MYD: 102757190(DUSP6)
MNA: 107538934(DUSP6)
HAI: 109392791(DUSP6)
DRO: 112315297(DUSP6)
PALE: 102884454(DUSP6)
RAY: 107520910(DUSP6)
MJV: 108407733(DUSP6)
LAV: 100655977(DUSP6)
TMU: 101344321
MDO: 100014655(DUSP6)
SHR: 100921269(DUSP6)
PCW: 110213205(DUSP6)
OAA: 100080443 114816698(DUSP6)
GGA: 374272(DUSP6)
MGP: 100542108(DUSP6)
CJO: 107311338(DUSP6)
NMEL: 110403090(DUSP6)
APLA: 101789550(DUSP6)
ACYG: 106036888(DUSP6)
TGU: 100222847(DUSP6)
LSR: 110469366(DUSP6)
SCAN: 103813409(DUSP6)
GFR: 102045296(DUSP6)
FAB: 101810587(DUSP6)
PHI: 102111436(DUSP6)
PMAJ: 107205186(DUSP6)
CCAE: 111933474(DUSP6)
CCW: 104698486(DUSP6)
ETL: 114063221(DUSP6)
FPG: 101922044(DUSP6)
FCH: 102046230(DUSP6)
CLV: 102098608(DUSP6)
EGZ: 104134497(DUSP6)
NNI: 104011638(DUSP6)
ACUN: 113489252(DUSP6)
PADL: 103914681(DUSP6)
AAM: 106488179(DUSP6)
ASN: 102372926(DUSP6)
AMJ: 102567008(DUSP6)
PSS: 102443378(DUSP6)
CMY: 102936123(DUSP6)
CPIC: 101953255(DUSP6)
ACS: 100558871(dusp6)
PVT: 110069921(DUSP6)
PBI: 103060298(DUSP6)
PMUR: 107283121(DUSP6)
TSR: 106551711(DUSP6)
PMUA: 114605192(DUSP6)
GJA: 107122829
XLA: 100505429 398829(dusp6.L) 495060
XTR: 733815(dusp6)
NPR: 108787235(DUSP6)
DRE: 353314(dusp6)
IPU: 108269200(dusp6)
PHYP: 113546656(dusp6)
AMEX: 103030496(dusp6)
EEE: 113584985
TRU: 100137150(dusp6)
NCC: 104948972(dusp6)
MZE: 101468411(dusp6)
ONL: 100708360(dusp6)
OLA: 101164462(dusp6)
XMA: 102233359(dusp6)
XCO: 114159540(dusp6)
PRET: 103465624(dusp6)
CVG: 107083225(dusp6)
NFU: 107373573
KMR: 108248253(dusp6)
ALIM: 106536807
AOCE: 111572786(dusp6)
CSEM: 103379594(dusp6)
POV: 109624493(dusp6)
LCF: 108894031(dusp6)
SDU: 111222512(dusp6)
SLAL: 111655570(dusp6)
HCQ: 109530907(dusp6)
BPEC: 110155113(dusp6)
MALB: 109956469(dusp6)
SASA: 100306828(dus6) 106573116
OTW: 112218860(dusp6) 112252656
ELS: 105018300(dusp6)
LCM: 102352064(DUSP6)
CMK: 103179844(dusp6)
RTP: 109923680
CIN: 778898(dusp6.9)
AQU: 100632228
 » show all
Reference
PMID:8670865
  Authors
Groom LA, Sneddon AA, Alessi DR, Dowd S, Keyse SM
  Title
Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase.
  Journal
EMBO J 15:3621-32 (1996)
DOI:10.1002/j.1460-2075.1996.tb00731.x
  Sequence
[hsa:1848]
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