KEGG   ORTHOLOGY: K22114
Entry
K22114                      KO                                     

Name
ddaF
Definition
dapdiamide synthase [EC:6.3.2.47]
Pathway
ko00997  Biosynthesis of various secondary metabolites - part 3
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00904  Dapdiamides biosynthesis, L-2,3-diaminopropanoate => dapdiamide A/B/C
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00997 Biosynthesis of various secondary metabolites - part 3
    K22114  ddaF; dapdiamide synthase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.47  dapdiamide synthase
     K22114  ddaF; dapdiamide synthase
Other DBs
RN: R10942 R10943 R10944
Genes
SPE: Spro_0344
SPLY: Q5A_016905(purD_2)
PVA: Pvag_pPag20162 Pvag_pPag20163
PAGC: BEE12_22710
AG: ADN39488(ddaF)
Reference
  Authors
Hollenhorst MA, Clardy J, Walsh CT
  Title
The ATP-dependent amide ligases DdaG and DdaF assemble the fumaramoyl-dipeptide scaffold of the dapdiamide antibiotics.
  Journal
Biochemistry 48:10467-72 (2009)
DOI:10.1021/bi9013165
  Sequence
LinkDB

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