KEGG   ORTHOLOGY: K22480
Entry
K22480                      KO                                     

Name
hdrA1
Definition
heterodisulfide reductase subunit A1 [EC:1.8.7.3]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K22480  hdrA1; heterodisulfide reductase subunit A1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.7  With an iron-sulfur protein as acceptor
    1.8.7.3  ferredoxin:CoB-CoM heterodisulfide reductase
     K22480  hdrA1; heterodisulfide reductase subunit A1
Other DBs
RN: R11931
COG: COG1148
Genes
DTO: TOL2_C11620(hdlA3)
MST: Msp_0127(hdrA2)
METB: AW729_06500
MSI: Msm_0082
MEB: Abm4_0695(hdrA1)
MMIL: sm9_0984(hdrA1)
MEYE: TL18_05450
MOL: YLM1_0874
MEL: Metbo_1205 Metbo_2477
MEW: MSWAN_0048 MSWAN_1005
METH: MBMB1_1157
MFC: BRM9_1364(hdrA1)
MCUB: MCBB_1057(hdrA1)
MBAR: MSBR2_1663
MBAK: MSBR3_1666
MAC: MA_3128(hdrA)
MMA: MM_0387
MMAC: MSMAC_0918
METM: MSMTP_2284
MTHR: MSTHT_2519
MTHE: MSTHC_0766
MHOR: MSHOH_1117
MMH: Mmah_0415
MPD: MCP_1989(hdrA_mvhD)
MEZ: Mtc_1471(hdrA1)
RCI: LRC437(hdrA-1)
 » show all
Reference
  Authors
Buan NR, Metcalf WW
  Title
Methanogenesis by Methanosarcina acetivorans involves two structurally and functionally distinct classes of heterodisulfide reductase.
  Journal
Mol Microbiol 75:843-53 (2010)
DOI:10.1111/j.1365-2958.2009.06990.x
  Sequence
[mac:MA_3128]
LinkDB

KEGG   ORTHOLOGY: K22481
Entry
K22481                      KO                                     

Name
hdrB1
Definition
heterodisulfide reductase subunit B1 [EC:1.8.7.3]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K22481  hdrB1; heterodisulfide reductase subunit B1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.7  With an iron-sulfur protein as acceptor
    1.8.7.3  ferredoxin:CoB-CoM heterodisulfide reductase
     K22481  hdrB1; heterodisulfide reductase subunit B1
Other DBs
RN: R11931
COG: COG2048
Genes
BTS: Btus_2497
KYR: CVV65_12495
SAY: TPY_3530
SAP: Sulac_1385
STHR: BXT84_06255
AFO: Afer_0965
SYL: AWQ21_15430
CAN: Cyan10605_2791
CYC: PCC7424_1698
OAC: Oscil6304_5896
TRO: trd_0154
CTS: Ctha_0137
MST: Msp_0126(hdrB2)
MSI: Msm_0083
MEB: Abm4_0694(hdrB1)
MMIL: sm9_0983(hdrB1)
MEYE: TL18_05455
MOL: YLM1_0875
METH: MBMB1_1152
MFC: BRM9_1363(hdrB3)
MCUB: MCBB_1056(hdrB1)
MBAR: MSBR2_1665
MBAK: MSBR3_1668
MAC: MA_3126(hdrB)
MMA: MM_0389
MMAC: MSMAC_0916
METM: MSMTP_2282
MTHR: MSTHT_2521
MTHE: MSTHC_0764
MHOR: MSHOH_1119
MMH: Mmah_0417
MPD: MCP_1990(hdrB-2)
MEZ: Mtc_1470(hdrB-1)
RCI: LRC438(hdrB-1)
 » show all
Reference
  Authors
Buan NR, Metcalf WW
  Title
Methanogenesis by Methanosarcina acetivorans involves two structurally and functionally distinct classes of heterodisulfide reductase.
  Journal
Mol Microbiol 75:843-53 (2010)
DOI:10.1111/j.1365-2958.2009.06990.x
  Sequence
[mac:MA_3126]
LinkDB

KEGG   ORTHOLOGY: K22482
Entry
K22482                      KO                                     

Name
hdrC1
Definition
heterodisulfide reductase subunit C1 [EC:1.8.7.3]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K22482  hdrC1; heterodisulfide reductase subunit C1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.7  With an iron-sulfur protein as acceptor
    1.8.7.3  ferredoxin:CoB-CoM heterodisulfide reductase
     K22482  hdrC1; heterodisulfide reductase subunit C1
Other DBs
RN: R11931
COG: COG1150
Genes
HHC: M911_11240
EBS: ECTOBSL9_0287
TGR: Tgr7_2216
TKM: TK90_0632
TNI: TVNIR_3249
TVR: TVD_10650
APRS: BI364_13815
ACII: C4901_12980
SULF: CAP31_01840
SPLB: SFPGR_29470
HDN: Hden_0689
RHC: RGUI_1283
AFR: AFE_2555
ACU: Atc_2352
BTS: Btus_2498
SLP: Slip_1202
SAY: TPY_3531
AFO: Afer_0964
TRO: trd_0155
AFD: Alfi_2099
ASH: AL1_26650
CTS: Ctha_0138
MST: Msp_0125(hdrC2)
MSI: Msm_0084
MEB: Abm4_0693(hdrC1)
MMIL: sm9_0982(hdrC1)
MEYE: TL18_05460
MOL: YLM1_0876
METH: MBMB1_1151
MFC: BRM9_1362(hdrC2)
MCUB: MCBB_1055(hdrC1)
MBAR: MSBR2_1664
MBAK: MSBR3_1667
MAC: MA_3127(hdrC)
MMA: MM_0388
MMAC: MSMAC_0917
METM: MSMTP_2283
MTHR: MSTHT_2520
MTHE: MSTHC_0765
MHOR: MSHOH_1118
MMH: Mmah_0416
MPD: MCP_1991(hdrC-2)
MEZ: Mtc_1469(hdrC-1)
RCI: LRC439(hdrC-1)
 » show all
Reference
  Authors
Buan NR, Metcalf WW
  Title
Methanogenesis by Methanosarcina acetivorans involves two structurally and functionally distinct classes of heterodisulfide reductase.
  Journal
Mol Microbiol 75:843-53 (2010)
DOI:10.1111/j.1365-2958.2009.06990.x
  Sequence
[mac:MA_3127]
LinkDB

KEGG   ORTHOLOGY: K03388
Entry
K03388                      KO                                     

Name
hdrA2
Definition
heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K03388  hdrA2; heterodisulfide reductase subunit A2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.7  With an iron-sulfur protein as acceptor
    1.8.7.3  ferredoxin:CoB-CoM heterodisulfide reductase
     K03388  hdrA2; heterodisulfide reductase subunit A2
   1.8.98  With other, known, physiological acceptors
    1.8.98.4  coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase
     K03388  hdrA2; heterodisulfide reductase subunit A2
    1.8.98.5  H2:CoB-CoM heterodisulfide,ferredoxin reductase
     K03388  hdrA2; heterodisulfide reductase subunit A2
    1.8.98.6  formate:CoB-CoM heterodisulfide,ferredoxin reductase
     K03388  hdrA2; heterodisulfide reductase subunit A2
Other DBs
RN: R11928 R11931 R11943 R11944
COG: COG1148
Genes
TMB: Thimo_0253
HHC: M911_11230
EBS: ECTOBSL9_0285
TGR: Tgr7_2214
TKM: TK90_0634
TNI: TVNIR_3247(hdrA_[H])
TVR: TVD_10640
APRS: BI364_13805
ACII: C4901_12970
CBX: Cenrod_2147(hdrA)
SPLB: SFPGR_29450(hdrA)
SNIV: SFSGTM_27290(hdrA)
SLAC: SKTS_06230(hdrA-2)
GSU: GSU0090(hdrA)
GSK: KN400_0065(hdrA)
GME: Gmet_2084(bamE) Gmet_3426(hdrA)
GLO: Glov_0864
GBM: Gbem_0030(hdrA) Gbem_1447(bamE)
GEO: Geob_0215(bamE-1) Geob_0231(bamE-2) Geob_3723(hdrA)
DVU: DVU2402(hdrA)
DVL: Dvul_0828
DVM: DvMF_0324
DDS: Ddes_2100
DMA: DMR_01920(hdrA) DMR_22120
DHY: DESAM_21330(hdrA)
DGG: DGI_1050(hdrA)
DTR: RSDT_0567(hdrA)
DPI: BN4_11860(hdrA)
DPS: DP1010
DOL: Dole_1159
DML: Dmul_02770(hdrA1) Dmul_24500(bamE) Dmul_28860(hdrA2)
DAT: HRM2_06460 HRM2_11710(hdrA1) HRM2_11850(hdrA2) HRM2_14330(hdrA3) HRM2_14340(hdrA3') HRM2_22750(hdrA4)
DTO: TOL2_C03750(bamE1) TOL2_C11590(hdlA2) TOL2_C11630(hdlA3?) TOL2_C17900(hdlA5) TOL2_C24180(hdlA6) TOL2_C25730(hdlA7) TOL2_C28760(hdlA8) TOL2_C28830(hdlA9) TOL2_C41400(bamE2) TOL2_C43540(bamE3)
ADE: Adeh_4164
HDN: Hden_0691
BLAG: BLTE_14930(hdrA-2)
RHC: RGUI_1281
AFR: AFE_2553
ATX: GCD22_03148(hdrA) GCD22_03279(hdrA)
BTS: Btus_2496
RCH: RUM_10980
BPRO: PMF13cell1_01672(ndhI_2)
SWO: Swol_0397
SALQ: SYNTR_0264
PTH: PTH_1410(HdrA)
SGY: Sgly_1900
HMO: HM1_2008(hdrA)
SAY: TPY_3529(hdrA)
MTA: Moth_1453
MTHZ: MOTHA_c08510(ndhI3) MOTHA_c15280(mnmC2)
STED: SPTER_13760(mnmC)
AFO: Afer_0966
DFO: Dform_00920(hdrA) Dform_00941(hdrA)
TRO: trd_0153
OTE: Oter_3677
APS: CFPG_240
AFD: Alfi_2101
ASH: AL1_26630
BACC: BRDCF_p1060 BRDCF_p823(hdrA) BRDCF_p824(hdrA2)
CTE: CT1246(hdrA-2)
CPC: Cpar_0949
CCH: Cag_1029
CLI: Clim_1200
PVI: Cvib_0843
PLT: Plut_1109
PPH: Ppha_1306
CTS: Ctha_0136
AAE: aq_395(hdrA)
HTH: HTH_1881(hdrA)
TAL: Thal_1346
CABY: Cabys_1917
CTHI: THC_1756
BANA: BARAN1_0338(hdrA)
MMP: MMP0825(hdrA) MMP1697(hdrA)
MMD: GYY_04785
MMAK: MMKA1_09100(hdrA) MMKA1_19310(hdrA)
MMAO: MMOS7_08880(hdrA) MMOS7_18120(hdrA)
MMAD: MMJJ_01720(hdrA) MMJJ_11320(hdrA2)
MTH: MTH_1381
MMG: MTBMA_c17680(hdrA)
METC: MTCT_1255
MWO: MWSIV6_1762(hdrA)
METE: tca_01335(rsxB_2)
MST: Msp_1476(hdrA1)
MRU: mru_0117(hdrA)
MSI: Msm_1336
MEB: Abm4_1691(hdrA2)
MMIL: sm9_2251(hdrA2)
MEYE: TL18_00375
MOL: YLM1_1554
METH: MBMB1_1958(hdrA)
MFC: BRM9_2298(hdrA2)
MFI: DSM1535_1232(hdrA)
MCUB: MCBB_2243(hdrA3)
MFV: Mfer_0184
MKA: MK0249(hdrA_1) MK0265(hdrA_2)
MEAR: Mpt1_c10580(hdrA)
MARC: AR505_1479
ABI: Aboo_0977
MBAR: MSBR2_0910
MBAK: MSBR3_0798
MAC: MA_2868(hdrA)
MMA: MM_0056
METM: MSMTP_1469
MTHR: MSTHT_0375
MTHE: MSTHC_0346
MBU: Mbur_0552(hdrA)
MMET: MCMEM_1365
MMH: Mmah_0955
MTP: Mthe_1576
MCJ: MCON_3279(hdrA)
MHI: Mhar_0607
MBG: BN140_0752(hdrA1) BN140_1728(hdrA3)
MEMA: MMAB1_0971(hdrA) MMAB1_2223(hdrA)
MPD: MCP_1576(hdrA-1) MCP_2768(hdrA-2)
MEZ: Mtc_2473(hdrA-2)
RCI: RCIX596(hdrA-2) RRC258(hdrA-3)
HDF: AArcSl_1855(hdrA)
STO: STK_18730
SSO: SSO1131(hdrA)
SOL: Ssol_2101
SSOA: SULA_2132
SSOL: SULB_2133
SSOF: SULC_2131
SAI: Saci_0328(hdrA)
SID: M164_1089
SII: LD85_1217
SIH: SiH_1060
SIR: SiRe_0973
SIC: SiL_0979
MSE: Msed_1545
MCN: Mcup_0686
AHO: Ahos_1694
STEP: IC006_0777
BARC: AOA65_1112(hdrA_1) AOA65_1402(hdrA_3) AOA65_1719(hdlA_2) AOA65_1995(hdrA_4)
BARB: AOA66_0155(hdrA_1) AOA66_1510(hdrA_2) AOA66_1512(hdlA_2) AOA66_1513(hdrA_3) AOA66_1526(hdrA_4)
LOKI: Lokiarch_00290(hdrA_1) Lokiarch_01240(hdrA_2) Lokiarch_08680(hdrA_4) Lokiarch_09900(hdrA_5) Lokiarch_10040(hdlA_3) Lokiarch_17940(hdlA_5) Lokiarch_23600(hdrA_8) Lokiarch_25880(hdrA_9) Lokiarch_28050(hdrA_10) Lokiarch_40200(hdrA_13) Lokiarch_41160(hdrA_15) Lokiarch_49330(hdrA_16)
PSYT: DSAG12_01136(hdrA_1) DSAG12_01147(hdrA_2) DSAG12_02253(hdrA_3) DSAG12_02805(hdrA_4) DSAG12_03220(hdrA_5) DSAG12_03721(hdrA_6) DSAG12_03723(hdlA_4) DSAG12_03724(hdrA_7)
 » show all
Reference
PMID:2121478
  Authors
Hedderich R, Berkessel A, Thauer RK
  Title
Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg).
  Journal
Eur J Biochem 193:255-61 (1990)
DOI:10.1111/j.1432-1033.1990.tb19331.x
  Sequence
Reference
PMID:8119281
  Authors
Setzke E, Hedderich R, Heiden S, Thauer RK
  Title
H2: heterodisulfide oxidoreductase complex from Methanobacterium thermoautotrophicum. Composition and properties.
  Journal
Eur J Biochem 220:139-48 (1994)
DOI:10.1111/j.1432-1033.1994.tb18608.x
  Sequence
Reference
  Authors
Mander GJ, Pierik AJ, Huber H, Hedderich R
  Title
Two distinct heterodisulfide reductase-like enzymes in the sulfate-reducing archaeon Archaeoglobus profundus.
  Journal
Eur J Biochem 271:1106-16 (2004)
DOI:10.1111/j.1432-1033.2004.04013.x
  Sequence
[apo:Arcpr_1555] [afu:AF_1377]
LinkDB

KEGG   ORTHOLOGY: K03389
Entry
K03389                      KO                                     

Name
hdrB2
Definition
heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K03389  hdrB2; heterodisulfide reductase subunit B2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.7  With an iron-sulfur protein as acceptor
    1.8.7.3  ferredoxin:CoB-CoM heterodisulfide reductase
     K03389  hdrB2; heterodisulfide reductase subunit B2
   1.8.98  With other, known, physiological acceptors
    1.8.98.4  coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase
     K03389  hdrB2; heterodisulfide reductase subunit B2
    1.8.98.5  H2:CoB-CoM heterodisulfide,ferredoxin reductase
     K03389  hdrB2; heterodisulfide reductase subunit B2
    1.8.98.6  formate:CoB-CoM heterodisulfide,ferredoxin reductase
     K03389  hdrB2; heterodisulfide reductase subunit B2
Other DBs
RN: R11928 R11931 R11943 R11944
COG: COG2048
Genes
TIG: THII_2280
THIS: HZT40_21385
TVI: Thivi_3111
TMB: Thimo_0248
TSY: THSYN_16425
HHC: M911_11215 M911_11235
EBS: ECTOBSL9_0282 ECTOBSL9_0286
TGR: Tgr7_2211 Tgr7_2215
TKM: TK90_0633 TK90_0637
TNI: TVNIR_3244(hdrB_[H]) TVNIR_3248(hdlB_[H])
SLIM: SCL_2520
TBN: TBH_C2777
ENM: EBS_2145(hdrB)
SHD: SUTH_02769(hdrB)
TBD: Tbd_1645
SDR: SCD_n01881(hdrB)
SLAC: SKTS_06180(hdrB) SKTS_11890
GSU: GSU0091(hdrB)
GSK: KN400_0066(hdrB)
GME: Gmet_3425(hdrB)
GLO: Glov_0862
GBM: Gbem_0031(hdrB)
GEO: Geob_3724(hdrB)
GEM: GM21_0030
DVU: DVU2403(hdrB)
DVL: Dvul_0827
DVM: DvMF_0323
DDS: Ddes_2099
DMA: DMR_01910(hdrB)
DGG: DGI_1049(hdrB)
DTR: RSDT_0566(hdrB)
DAS: Daes_0784
DPI: BN4_11859(hdrB)
DOL: Dole_1160
DML: Dmul_28870(hdrB)
DAT: HRM2_22770(hdrD2')
SFU: Sfum_0819
BLAG: BLTE_14980
ATX: GCD22_01577(hdrB1) GCD22_02661(hdrB1) GCD22_03145(hdrB) GCD22_03149(hdrB1) GCD22_03192(hdrB1)
RCH: RUM_10960
RUM: CK1_05040
BPRO: PMF13cell1_01670(lutA)
SWO: Swol_0395
SALQ: SYNTR_0262
PTH: PTH_1412(HdrB)
SGY: Sgly_1901
HMO: HM1_2007
HCV: FTV88_1703(hdrB)
CHY: CHY_0929
ADG: Adeg_1334
TACI: TDSAC_1307
STED: SPTER_13750(sdhE_1)
DFO: Dform_00942(hdrB)
OTE: Oter_3676
TTF: THTE_4308
APS: CFPG_239
AFD: Alfi_2100
CTE: CT1245
CPC: Cpar_0950
CCH: Cag_1028
CLI: Clim_1201
PVI: Cvib_0844
PLT: Plut_1108
PPH: Ppha_1307
AAE: aq_400(hdrB)
HTH: HTH_1878(hdrB1) HTH_1882(hdrB2)
TTK: TST_1519(hdrB)
CABY: Cabys_1918
MMP: MMP1053(hdrB2) MMP1155(hdrB1)
MMAK: MMKA1_12180(hdrB) MMKA1_13330(hdrB)
MMAO: MMOS7_11480(hdrB) MMOS7_12630(hdrB)
MMAD: MMJJ_16900 MMJJ_17970(lutA)
MAE: Maeo_0308
METF: CFE53_06410(hdrB)
MTH: MTH_1879
MMG: MTBMA_c04500(hdrB)
METC: MTCT_1717
MWO: MWSIV6_0410(hdrB)
METE: tca_01815(lutA)
METK: FVF72_02310(hdrB)
MTHM: FZP57_01925(hdrB)
MST: Msp_1013(hdrB1)
MRU: mru_0817(hdrB1)
MSI: Msm_0795
MEB: Abm4_1308(hdrB2)
MMIL: sm9_1716(hdrB3)
MEYE: TL18_07635
MOL: YLM1_0405
METH: MBMB1_1274(hdrB)
MFC: BRM9_0490(hdrB1)
MFI: DSM1535_0471(hdrB)
MCUB: MCBB_1489(hdrB3)
METT: CIT01_08470(hdrB)
METO: CIT02_11685(hdrB)
MFV: Mfer_0739
MKA: MK0572(hdrB)
AFU: AF_1375
MEAR: Mpt1_c02970(hdrB1) Mpt1_c08830(hdrB2)
MARC: AR505_0274
ABI: Aboo_0976
MBAR: MSBR2_3160
MBAK: MSBR3_3156
MAC: MA_4237(hdrB)
METM: MSMTP_0364
MTHR: MSTHT_1573
MTHE: MSTHC_1716
MFZ: AOB57_006960(hdrB)
MBU: Mbur_1517(hdrB)
MMET: MCMEM_1990
MMH: Mmah_1786
MZI: HWN40_01880(hdrB)
MTP: Mthe_1573
MCJ: MCON_3283(hdrB)
MHI: Mhar_0604
MHU: Mhun_1837
MLA: Mlab_0240
MBG: BN140_1727(hdrB)
MEMA: MMAB1_2222(hdrB)
MBN: Mboo_0589
MPL: Mpal_2240
MPD: MCP_1577(hdrB-1) MCP_2769(hdrB-3)
MEZ: Mtc_2474(hdrB-2)
RCI: RCIX595(hdrB-2) RRC257(hdrB-3)
SSO: SSO1129(hdrB-1) SSO1135(hdrB-2)
SAI: Saci_0325(hdrB) Saci_0329
KCR: Kcr_0767
BARC: AOA65_1401(hdrB_2) AOA65_1887(hdrB_3) AOA65_1993(hdrB_4)
BARB: AOA66_1507(hdrB_1) AOA66_1731(hdrB_2)
LOKI: Lokiarch_01260(hdrB_1) Lokiarch_23590(hdrB_2) Lokiarch_39150(hdrB_3) Lokiarch_45510(hdrB_4)
PSYT: DSAG12_01137(hdrB_1) DSAG12_01146(hdrB_2) DSAG12_01161(hdrB_3) DSAG12_02807(hdrB_4) DSAG12_03223(hdrB_5) DSAG12_03725(hdrB_6) DSAG12_03952(hdrB_7)
 » show all
Reference
PMID:2121478
  Authors
Hedderich R, Berkessel A, Thauer RK
  Title
Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg).
  Journal
Eur J Biochem 193:255-61 (1990)
DOI:10.1111/j.1432-1033.1990.tb19331.x
  Sequence
Reference
PMID:8119281
  Authors
Setzke E, Hedderich R, Heiden S, Thauer RK
  Title
H2: heterodisulfide oxidoreductase complex from Methanobacterium thermoautotrophicum. Composition and properties.
  Journal
Eur J Biochem 220:139-48 (1994)
DOI:10.1111/j.1432-1033.1994.tb18608.x
  Sequence
Reference
  Authors
Mander GJ, Pierik AJ, Huber H, Hedderich R
  Title
Two distinct heterodisulfide reductase-like enzymes in the sulfate-reducing archaeon Archaeoglobus profundus.
  Journal
Eur J Biochem 271:1106-16 (2004)
DOI:10.1111/j.1432-1033.2004.04013.x
  Sequence
[apo:Arcpr_1553] [afu:AF_1375]
LinkDB

KEGG   ORTHOLOGY: K03390
Entry
K03390                      KO                                     

Name
hdrC2
Definition
heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K03390  hdrC2; heterodisulfide reductase subunit C2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.7  With an iron-sulfur protein as acceptor
    1.8.7.3  ferredoxin:CoB-CoM heterodisulfide reductase
     K03390  hdrC2; heterodisulfide reductase subunit C2
   1.8.98  With other, known, physiological acceptors
    1.8.98.4  coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase
     K03390  hdrC2; heterodisulfide reductase subunit C2
    1.8.98.5  H2:CoB-CoM heterodisulfide,ferredoxin reductase
     K03390  hdrC2; heterodisulfide reductase subunit C2
    1.8.98.6  formate:CoB-CoM heterodisulfide,ferredoxin reductase
     K03390  hdrC2; heterodisulfide reductase subunit C2
Other DBs
RN: R11928 R11931 R11943 R11944
COG: COG1150
Genes
TMB: Thimo_0247
HHC: M911_11220
EBS: ECTOBSL9_0283
TGR: Tgr7_2212
TKM: TK90_0636
TNI: TVNIR_3245(hdlC_[H])
TVR: TVD_10630
APRS: BI364_13795
ACII: C4901_12960
SULF: CAP31_01860
SPLB: SFPGR_29430(hdrC)
SNIV: SFSGTM_27270(hdrC)
SLAC: SKTS_06170
GSU: GSU0092(hdrC)
GSK: KN400_0067(hdrC)
GME: Gmet_3424(hdrC)
GLO: Glov_0861
GBM: Gbem_0032(hdrC)
GEO: Geob_3725(hdrC)
GEM: GM21_0031
DVU: DVU2404(hdrC)
DVL: Dvul_0826
DVM: DvMF_0322
DDS: Ddes_2098
DMA: DMR_01900(hdrC)
DGG: DGI_1048(hdrC)
DTR: RSDT_0565(hdrC)
DAS: Daes_0783
DPI: BN4_11858(hdrC)
DSF: UWK_01755
DOL: Dole_1161
DML: Dmul_28880(hdrC)
DAT: HRM2_22760(hdrD2)
DTO: TOL2_C17910(hdlC)
SFU: Sfum_0820
DBR: Deba_2022
HDN: Hden_0693
BLAG: BLTE_14840
RHC: RGUI_1279
AFR: AFE_2551
ACU: Atc_2348
ATX: GCD22_03146(hdlC)
RCH: RUM_10970
RUM: CK1_05050
BPRO: PMF13cell1_01671(rsxC_1)
SWO: Swol_0394
SLP: Slip_2075
SALQ: SYNTR_0261
PTH: PTH_1413(GlpC)
DAU: Daud_0563
SGY: Sgly_1902
HMO: HM1_2006
CHY: CHY_0927
DFO: Dform_00943(hdrC)
APS: CFPG_238
AAE: aq_391 aq_398(hdrC)
HTH: HTH_1879(hdrC1) HTH_1883(hdrC2)
TTK: TST_1518(hdrC)
BANA: BARAN1_0333(hdrC)
MMP: MMP1054(hdrC2) MMP1154(hdrC1)
MMAK: MMKA1_12190(hdrC) MMKA1_13320(hdrC)
MMAO: MMOS7_11490(hdrC) MMOS7_12620(hdrC)
MAE: Maeo_0307
METF: CFE53_02215(hdrC) CFE53_06415(hdrC)
MTH: MTH_1878
MMG: MTBMA_c04490(hdrC)
METC: MTCT_1716
MWO: MWSIV6_0409(hdrC)
METE: tca_01814
METK: FVF72_02315(hdrC)
MTHM: FZP57_01920(hdrC)
MST: Msp_1014(hdrC1)
MRU: mru_0816(hdrC)
MSI: Msm_0796
MEB: Abm4_1309(hdrC2)
MMIL: sm9_1717(hdrC2)
MEYE: TL18_07640
MOL: YLM1_0404
METH: MBMB1_1275
MFC: BRM9_0491(hdrC1)
MFI: DSM1535_0472(hdrC)
MCUB: MCBB_1490(hdrC3)
METT: CIT01_08465(hdrC)
METO: CIT02_11680(hdrC)
MFV: Mfer_0740
MKA: MK0573(hdrC)
AFU: AF_1376
GAH: GAH_01704
MEAR: Mpt1_c02960(hdrC1) Mpt1_c08840(hdrC2)
MARC: AR505_0273
ABI: Aboo_0975
MBAR: MSBR2_3161
MBAK: MSBR3_3157
MAC: MA_4236(hdrC)
MMA: MM_0979
METM: MSMTP_0365
MTHR: MSTHT_1572
MTHE: MSTHC_1717
MFZ: AOB57_006955(hdrC)
MBU: Mbur_1516(hdrC)
MMET: MCMEM_1991
MMH: Mmah_1787
MZI: HWN40_01885(hdrC)
MTP: Mthe_1574
MCJ: MCON_3282(hdrC)
MHI: Mhar_0605
MHU: Mhun_1836
MLA: Mlab_0239
MBG: BN140_1726(hdrC)
MEMA: MMAB1_2221(hdrC)
MBN: Mboo_0590
MPL: Mpal_2241
MPD: MCP_1578(hdrC-1) MCP_2770(hdrC-3)
MEZ: Mtc_2475(hdrC-2)
RCI: RCIX594(hdrC-2) RRC256(hdrC-3)
SSO: SSO1127(hdrC-1) SSO1134(hdrC-2)
SAI: Saci_0326 Saci_0334(hdrC)
VDI: Vdis_0690
VMO: VMUT_2339
KCR: Kcr_0766
BARC: AOA65_0030(hdrC_1) AOA65_1400(hdrC_2) AOA65_1888(hdrC_3) AOA65_1994(hdrC_4)
BARB: AOA66_1508(hdrC_1) AOA66_1732(hdrC_2)
LOKI: Lokiarch_01250(hdrC_1) Lokiarch_03060(hdrC_2) Lokiarch_23580(hdrC_3) Lokiarch_23870(hdrC_4) Lokiarch_39160(hdrC_5) Lokiarch_45500(hdrC_6)
PSYT: DSAG12_01138(hdrC_1) DSAG12_01145(hdrC_2) DSAG12_01162(hdrC_3) DSAG12_02806(hdrC_4) DSAG12_03218(hdrC_5) DSAG12_03726(hdrC_6) DSAG12_03953(hdrC_7)
 » show all
Reference
PMID:2121478
  Authors
Hedderich R, Berkessel A, Thauer RK
  Title
Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg).
  Journal
Eur J Biochem 193:255-61 (1990)
DOI:10.1111/j.1432-1033.1990.tb19331.x
  Sequence
Reference
PMID:8119281
  Authors
Setzke E, Hedderich R, Heiden S, Thauer RK
  Title
H2: heterodisulfide oxidoreductase complex from Methanobacterium thermoautotrophicum. Composition and properties.
  Journal
Eur J Biochem 220:139-48 (1994)
DOI:10.1111/j.1432-1033.1994.tb18608.x
  Sequence
Reference
  Authors
Mander GJ, Pierik AJ, Huber H, Hedderich R
  Title
Two distinct heterodisulfide reductase-like enzymes in the sulfate-reducing archaeon Archaeoglobus profundus.
  Journal
Eur J Biochem 271:1106-16 (2004)
DOI:10.1111/j.1432-1033.2004.04013.x
  Sequence
LinkDB

KEGG   ORTHOLOGY: K08264
Entry
K08264                      KO                                     

Name
hdrD
Definition
heterodisulfide reductase subunit D [EC:1.8.98.1]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K08264  hdrD; heterodisulfide reductase subunit D
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.98  With other, known, physiological acceptors
    1.8.98.1  dihydromethanophenazine:CoB-CoM heterodisulfide reductase
     K08264  hdrD; heterodisulfide reductase subunit D
Other DBs
RN: R04540
COG: COG1150
GO: 0051912
Genes
DAL: Dalk_1625 Dalk_4040 Dalk_4954
DTO: TOL2_C11570 TOL2_C26590
DTI: Desti_0745 Desti_5348 Desti_5359
SFU: Sfum_1176 Sfum_1801
DBR: Deba_2985
BJU: BJ6T_87480
BJP: RN69_42255
RHZ: RHPLAN_09760
BFD: NCTC4823_02385(fadF_3)
CLS: CXIVA_16140(GlpC)
STED: SPTER_30050(fadF)
AFO: Afer_2003
MBAS: ALGA_3860
CPI: Cpin_5887
FLN: FLA_3557
SGN: SGRA_1094
PHE: Phep_0746
SDJ: NCTC13534_04277(glpC)
STHA: NCTC11429_03180(glpC)
MUC: MuYL_1450
CHU: CHU_0123(ykgE)
DFE: Dfer_4016
SLI: Slin_5544
LBY: Lbys_2731
FAE: FAES_0224
HSW: Hsw_4302
FLM: MY04_1429
GFO: GFO_1636
GFL: GRFL_3307
FIN: KQS_07140
COC: Coch_0507
ZPR: ZPR_2739
MARM: YQ22_14830
CBAL: M667_12255
CBAT: M666_12175
DDO: I597_2441(glpC_2)
MLT: VC82_2479
NDO: DDD_3081
MPW: MPR_1407
WIN: WPG_3012
TMAR: MARIT_1250
SPON: HME9304_02805(glcD)
KAN: IMCC3317_06930(lutA)
MARF: CJ739_3272
MESQ: C7H62_2405
FBA: FIC_00133
FBU: UJ101_02687(glcD)
RAI: RA0C_1249
RAR: RIA_1247
RAG: B739_0901
RAE: G148_0626
RAT: M949_1368
EAO: BD94_3883
ELB: VO54_02815(lutA_1)
CHZ: CHSO_4739
CJG: NCTC13459_02299(glpC)
METC: MTCT_0104
METE: tca_00123(glpC)
MOL: YLM1_0621
METH: MBMB1_0927
FPL: Ferp_0942
GAC: GACE_1903
GAH: GAH_00753
MEAR: Mpt1_c14100(hdrD2)
MARC: AR505_0040
ABI: Aboo_0983
MBAR: MSBR2_2817
MBAK: MSBR3_1888
MAC: MA_0688(hdrD)
MMA: MM_1844(hdrD)
MMAC: MSMAC_1592
METM: MSMTP_2735
MTHR: MSTHT_2244
MTHE: MSTHC_1036
MHOR: MSHOH_3536
MPY: Mpsy_0936
MTP: Mthe_0980
MCJ: MCON_3442(hdrD)
MHI: Mhar_0793
MPL: Mpal_0771
IHO: Igni_1369
TPE: Tpen_0594
BARC: AOA65_0539(hdrD_2) AOA65_0555(hdrD_3) AOA65_1721(hdrD_4) AOA65_2237(hdrD_5)
BARB: AOA66_1745(hdrD_3) AOA66_1757(hdrD_4)
PSYT: DSAG12_01123(hdrD_1) DSAG12_02413(hdrD_2) DSAG12_02953(hdrD_3) DSAG12_03453(hdrD_6)
 » show all
Reference
  Authors
Mander GJ, Pierik AJ, Huber H, Hedderich R
  Title
Two distinct heterodisulfide reductase-like enzymes in the sulfate-reducing archaeon Archaeoglobus profundus.
  Journal
Eur J Biochem 271:1106-16 (2004)
DOI:10.1111/j.1432-1033.2004.04013.x
LinkDB

KEGG   ORTHOLOGY: K08265
Entry
K08265                      KO                                     

Name
hdrE
Definition
heterodisulfide reductase subunit E [EC:1.8.98.1]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K08265  hdrE; heterodisulfide reductase subunit E
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.98  With other, known, physiological acceptors
    1.8.98.1  dihydromethanophenazine:CoB-CoM heterodisulfide reductase
     K08265  hdrE; heterodisulfide reductase subunit E
Other DBs
RN: R04540
COG: COG1150
GO: 0051912
Genes
EVA: EIB75_06610
MBA: Mbar_A1598
MBY: MSBRM_2860
MBW: MSBRW_3133
MBAR: MSBR2_2818
MBAK: MSBR3_1887
MAC: MA_0687(hdrE)
MMA: MM_1843(hdrE)
MMAZ: MmTuc01_1919
MMJ: MSMAS_2839
MMAC: MSMAC_1591
METM: MSMTP_2736
MTHR: MSTHT_2243
MTHE: MSTHC_1037
MHOR: MSHOH_3537
MBU: Mbur_2436
MMET: MCMEM_0578
MMH: Mmah_0632
MPY: Mpsy_0935
MTP: Mthe_0981
MCJ: MCON_3441(hdrE)
MHI: Mhar_0792
MPL: Mpal_0770
 » show all
Reference
  Authors
Mander GJ, Pierik AJ, Huber H, Hedderich R
  Title
Two distinct heterodisulfide reductase-like enzymes in the sulfate-reducing archaeon Archaeoglobus profundus.
  Journal
Eur J Biochem 271:1106-16 (2004)
DOI:10.1111/j.1432-1033.2004.04013.x
LinkDB

KEGG   ORTHOLOGY: K14126
Entry
K14126                      KO                                     

Name
mvhA, vhuA, vhcA
Definition
F420-non-reducing hydrogenase large subunit [EC:1.12.99.- 1.8.98.5]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K14126  mvhA, vhuA, vhcA; F420-non-reducing hydrogenase large subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.98  With other, known, physiological acceptors
    1.8.98.5  H2:CoB-CoM heterodisulfide,ferredoxin reductase
     K14126  mvhA, vhuA, vhcA; F420-non-reducing hydrogenase large subunit
  1.12  Acting on hydrogen as donor
   1.12.99  With unknown physiological acceptors
    1.12.99.-  
     K14126  mvhA, vhuA, vhcA; F420-non-reducing hydrogenase large subunit
Other DBs
RN: R00019 R11943
COG: COG3259
Genes
CBX: Cenrod_2145(mvhA)
GSU: GSU2419(mvhL)
GSK: KN400_2367(mvhL)
GME: Gmet_3320(mvhL)
GLO: Glov_1553
GBM: Gbem_3884(mvhL)
GEM: GM21_3972
GAO: A2G06_05470
DSD: GD606_02930
DAF: Desaf_1384
DRT: Dret_2258
DPS: DP1013
DAL: Dalk_4962
DAT: HRM2_11740(mvhA)
ADE: Adeh_4162
DAU: Daud_1651
ADG: Adeg_2013
TACI: TDSAC_1304
DET: DET0615
DEH: cbdbA597
DEV: DhcVS_553(vhuA)
DMC: btf_575(vhcA)
DMD: dcmb_621(vhcA)
DMG: GY50_0541(mvhA)
DFO: Dform_00937(mvhA|vhcA)
OTE: Oter_3680
TTF: THTE_4313
CABY: Cabys_1914
BANA: BARAN1_0335(mvhA)
MJA: MJ_1192
MMP: MMP0823(vhcA) MMP1694(vhuA)
MMAK: MMKA1_09080(vhcA) MMKA1_19280(vhuA)
MMAO: MMOS7_08860(vhcA) MMOS7_18090(vhuA)
MMAD: MMJJ_01740(vhcA) MMJJ_11350(vhuA)
MTH: MTH_1134
MMG: MTBMA_c15170(mvhA)
METC: MTCT_1027
MWO: MWSIV6_1526(mvhA)
METE: tca_01090(hoxH)
MST: Msp_0316(mvhA)
MRU: mru_1906(mvhA)
MSI: Msm_0999
MEB: Abm4_1510(mvhA)
MMIL: sm9_2011(mvhA)
MEYE: TL18_09240
MOL: YLM1_1362
METH: MBMB1_1340(mvhA1) MBMB1_1661(mvhA3)
MFC: BRM9_0563(mvhA1) BRM9_0913(mvhA2)
MFI: DSM1535_0544(vhcA) DSM1535_0881(mvhA)
MCUB: MCBB_1580(vhcA) MCBB_1966(mvhA)
MFV: Mfer_0729
AFU: AF_1372
FPL: Ferp_0841
GAC: GACE_0711
GAH: GAH_02038
MEAR: Mpt1_c10550(mvhA)
MARC: AR505_1476
MBG: BN140_1835(mvhA)
MEMA: MMAB1_2368(vhcA)
MPI: Mpet_2718
MPD: MCP_2492(mvhA-1) MCP_2774(mvhA-2)
MEZ: Mtc_0109(mvhA-1) Mtc_2479(mvhA-2)
RCI: RCIX473(mvhA-1) RCIX590(mvhA-2)
KCR: Kcr_1119
BARC: AOA65_1722 AOA65_1885(mvhA)
BARB: AOA66_1505(mvhA_2)
PSYT: DSAG12_03951(vhcA)
 » show all
Reference
  Authors
Stojanowic A, Mander GJ, Duin EC, Hedderich R
  Title
Physiological role of the F420-non-reducing hydrogenase (Mvh) from Methanothermobacter marburgensis.
  Journal
Arch Microbiol 180:194-203 (2003)
DOI:10.1007/s00203-003-0577-9
  Sequence
LinkDB

KEGG   ORTHOLOGY: K14128
Entry
K14128                      KO                                     

Name
mvhG, vhuG, vhcG
Definition
F420-non-reducing hydrogenase small subunit [EC:1.12.99.- 1.8.98.5]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K14128  mvhG, vhuG, vhcG; F420-non-reducing hydrogenase small subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.98  With other, known, physiological acceptors
    1.8.98.5  H2:CoB-CoM heterodisulfide,ferredoxin reductase
     K14128  mvhG, vhuG, vhcG; F420-non-reducing hydrogenase small subunit
  1.12  Acting on hydrogen as donor
   1.12.99  With unknown physiological acceptors
    1.12.99.-  
     K14128  mvhG, vhuG, vhcG; F420-non-reducing hydrogenase small subunit
Other DBs
RN: R00019 R11943
COG: COG1941
Genes
CBX: Cenrod_2144(mvhG)
GSU: GSU2418(mvhS)
GSK: KN400_2366(mvhS)
GME: Gmet_3319(mvhS)
GLO: Glov_1552
GBM: Gbem_3885(mvhS)
GEM: GM21_3973
GAO: A2G06_05475
DSD: GD606_02925
DAF: Desaf_1385
DRT: Dret_2259
DPS: DP1012
DAL: Dalk_4963
DAT: HRM2_11730(mvhG)
ADE: Adeh_4163
DAU: Daud_1652
ADG: Adeg_2014
TACI: TDSAC_1305
DET: DET0614
DEH: cbdbA596
DEV: DhcVS_552(vhuG)
DMC: btf_574(vhcG)
DMD: dcmb_620(vhcG)
DMG: GY50_0540(mvhG)
DFO: Dform_00938(mvhG|vhcG)
OTE: Oter_3679
TTF: THTE_4312
CABY: Cabys_1915
BANA: BARAN1_0336(mvhG)
MJA: MJ_1191
MMP: MMP0822(vhcG) MMP1695(vhuG)
MMAK: MMKA1_09070(vhcG) MMKA1_19290(vhuG)
MMAO: MMOS7_08850(vhcG) MMOS7_18100(vhuG)
MMAD: MMJJ_01750(vhcG) MMJJ_11340(vhuG)
MTH: MTH_1135
MMG: MTBMA_c15180(mvhG)
METC: MTCT_1028
MWO: MWSIV6_1527(mvhG)
METE: tca_01091(hoxY)
MST: Msp_0315(mvhG)
MRU: mru_1907(mvhG)
MSI: Msm_1000
MEB: Abm4_1511(mvhG)
MMIL: sm9_2012(mvhG)
MEYE: TL18_09245
MOL: YLM1_1363
METH: MBMB1_1339 MBMB1_1662(mvhG)
MFC: BRM9_0562(mvhG1) BRM9_0914(mvhG2)
MCUB: MCBB_1579(vhuG) MCBB_1967(mvhG)
MFV: Mfer_0728
AFU: AF_1373
FPL: Ferp_0840
GAC: GACE_0710
GAH: GAH_02037
MEAR: Mpt1_c10560(mvhG)
MARC: AR505_1477
MBG: BN140_1834(mvhG)
MEMA: MMAB1_2367(vhcG)
MPI: Mpet_2719
MPD: MCP_2493(mvhG-1) MCP_2773(mvhG-2)
MEZ: Mtc_0111(mvhG-1) Mtc_2478(mvhG-2)
RCI: RCIX474(mvhG-1) RCIX591(mvhG-2)
KCR: Kcr_1118
BARC: AOA65_1723 AOA65_1886(mvhG)
BARB: AOA66_1506(mvhG)
PSYT: DSAG12_01149(mvhG_1) DSAG12_03954(mvhG_2)
 » show all
Reference
  Authors
Stojanowic A, Mander GJ, Duin EC, Hedderich R
  Title
Physiological role of the F420-non-reducing hydrogenase (Mvh) from Methanothermobacter marburgensis.
  Journal
Arch Microbiol 180:194-203 (2003)
DOI:10.1007/s00203-003-0577-9
  Sequence
LinkDB

KEGG   ORTHOLOGY: K14127
Entry
K14127                      KO                                     

Name
mvhD, vhuD, vhcD
Definition
F420-non-reducing hydrogenase iron-sulfur subunit [EC:1.12.99.- 1.8.98.5 1.8.98.6]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K14127  mvhD, vhuD, vhcD; F420-non-reducing hydrogenase iron-sulfur subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.98  With other, known, physiological acceptors
    1.8.98.5  H2:CoB-CoM heterodisulfide,ferredoxin reductase
     K14127  mvhD, vhuD, vhcD; F420-non-reducing hydrogenase iron-sulfur subunit
    1.8.98.6  formate:CoB-CoM heterodisulfide,ferredoxin reductase
     K14127  mvhD, vhuD, vhcD; F420-non-reducing hydrogenase iron-sulfur subunit
  1.12  Acting on hydrogen as donor
   1.12.99  With unknown physiological acceptors
    1.12.99.-  
     K14127  mvhD, vhuD, vhcD; F420-non-reducing hydrogenase iron-sulfur subunit
Other DBs
RN: R00019 R11943 R11944
COG: COG1908
Genes
TMB: Thimo_0254
CBX: Cenrod_2148(mvhD)
SLAC: SKTS_06250
GSK: KN400_0064(hdrG)
GME: Gmet_2083(bamF)
GUR: Gura_0148 Gura_3584
GLO: Glov_0865
GBM: Gbem_1448(bamF)
GEO: Geob_0216(bamF-1) Geob_0232(bamF-2) Geob_3721(hdrG)
GEM: GM21_2806
DMA: DMR_01930
DHY: DESAM_21329(vhcD)
DGG: DGI_1051(floxD)
DAS: Daes_0780
DPI: BN4_11861(mvhD)
DBA: Dbac_0851
DPS: DP1011
DOL: Dole_1158
DML: Dmul_28840(mvhD2)
DAT: HRM2_11720(mvhD2) HRM2_11860(mvhD3) HRM2_14350(mvhD4) HRM2_30880(mvhD7)
DTO: TOL2_C03740(bamF1) TOL2_C09050(mvhD1) TOL2_C11600(mvhD2) TOL2_C11640(mvhD3) TOL2_C17880(mvhD4) TOL2_C24190(mvhD5) TOL2_C25720(mvhD6) TOL2_C28770(mvhD7) TOL2_C28840(mvhD8) TOL2_C32340 TOL2_C33290(mvhD9) TOL2_C43530(bamF3)
BLAG: BLTE_14920(hdrG)
RCH: RUM_10990
RUM: CK1_05070
SWO: Swol_0398
SALQ: SYNTR_0265
DAE: Dtox_1354
PTH: PTH_1409(FrhD)
SGY: Sgly_1899
HCV: FTV88_1705(mvhD)
DFO: Dform_00940(mvhD|vhcD)
OTE: Oter_3678
TTF: THTE_4311
APS: CFPG_241
BACC: BRDCF_p825
MBAS: ALGA_3489
CPC: Cpar_0948
CCH: Cag_1030
CLI: Clim_1199
PVI: Cvib_0842
PLT: Plut_1110
PPH: Ppha_1305
CABY: Cabys_1916
TYE: THEYE_A1367(vhuD)
CTHI: THC_1757
BANA: BARAN1_0337(mvhD)
MMP: MMP0821(vhcD) MMP1696(vhuD)
MMAK: MMKA1_09060(vhcD) MMKA1_19300(vhuD)
MMAO: MMOS7_08840(vhcD) MMOS7_18110(vhuD)
MMAD: MMJJ_01760(vhcD) MMJJ_11330(vhuD)
MWO: MWSIV6_1528(mvhD) MWSIV6_1530(vhcD)
MST: Msp_0314(mvhD1) Msp_0638(mvhD2)
MRU: mru_1908(mvhD1) mru_2076(mvhD2)
MEB: Abm4_0853(mvhD2) Abm4_1512(mvhD)
MMIL: sm9_1348(flpD) sm9_2013(mvhD)
METH: MBMB1_1663(mvhD)
MFC: BRM9_0915(mvhD)
MFI: DSM1535_0883(mvhD)
MCUB: MCBB_1968(mvhD) MCBB_2030(vhcD)
MKA: MK0268(flpD_1) MK0627(flpD_2)
AFU: AF_1374
FPL: Ferp_0839
GAC: GACE_0709
GAH: GAH_02036
MEAR: Mpt1_c10570(vhcD)
MARC: AR505_1478
MMAC: MSMAC_2580
MHOR: MSHOH_1796
MPY: Mpsy_2942
MHU: Mhun_1839
MBG: BN140_1729(MvhD)
MEMA: MMAB1_2224(vhcD)
MPI: Mpet_2476
MPD: MCP_2767(mvhD-2)
MEZ: Mtc_2472(mvhD-2)
RCI: RCIX597(mvhD-1)
VMO: VMUT_2343
KCR: Kcr_1117
BARC: AOA65_1715(mvhD_1) AOA65_1718(mvhD_2) AOA65_1889(vhcD)
BARB: AOA66_1509(vhcD) AOA66_1511(mvhD)
LOKI: Lokiarch_25870(mvhD_2)
PSYT: DSAG12_01135(mvhD_1) DSAG12_01148(mvhD_2) DSAG12_02804(mvhD_4) DSAG12_03720(vhcD) DSAG12_03722(mvhD_5)
 » show all
Reference
  Authors
Stojanowic A, Mander GJ, Duin EC, Hedderich R
  Title
Physiological role of the F420-non-reducing hydrogenase (Mvh) from Methanothermobacter marburgensis.
  Journal
Arch Microbiol 180:194-203 (2003)
DOI:10.1007/s00203-003-0577-9
  Sequence
LinkDB

KEGG   ORTHOLOGY: K22516
Entry
K22516                      KO                                     

Name
fdhA
Definition
formate dehydrogenase (coenzyme F420) alpha subunit [EC:1.17.98.3 1.8.98.6]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K22516  fdhA; formate dehydrogenase (coenzyme F420) alpha subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.98  With other, known, physiological acceptors
    1.8.98.6  formate:CoB-CoM heterodisulfide,ferredoxin reductase
     K22516  fdhA; formate dehydrogenase (coenzyme F420) alpha subunit
  1.17  Acting on CH or CH2 groups
   1.17.98  With other, known, physiological acceptors
    1.17.98.3  formate dehydrogenase (coenzyme F420)
     K22516  fdhA; formate dehydrogenase (coenzyme F420) alpha subunit
Other DBs
RN: R10797 R11944
COG: COG3383
GO: 0043794
Genes
VNA: PN96_21155
VEJ: VEJY3_20411
PGB: H744_1c0419
PSH: Psest_3905
PSTU: UIB01_19765
PCH: EY04_14750
PSED: DM292_16890
GNI: GNIT_2862
CHIZ: HQ393_09255
CFON: HZU75_11945
CCO: CCC13826_0200(fdhH)
CCOC: CCON33237_0536(fdhH)
CGRA: CGRAC_1361(fdhH)
CPIN: CPIN18020_0262(fdhH)
CGEO: CGEO_1649(fdhH)
AHS: AHALO_1025(fdhH)
AMAR: AMRN_1963(fdhH)
ACAA: ACAN_2017(fdhH)
SULJ: SJPD1_1032
GEO: Geob_0149
PCA: Pcar_2701
DSF: UWK_03159
DAT: HRM2_11880(fdhA3) HRM2_14370(fdhA4)
DALK: DSCA_57160
EFS: EFS1_1216
ENE: ENT_08450
CSQ: CSCA_0253
DSY: DSY1990
DHD: Dhaf_3153
SFI: SFUL_466
MJA: MJ_0006
MMP: MMP0138(fdhA) MMP1298(fdhA)
MMAK: MMKA1_01430(fdhA) MMKA1_15230(fdhA)
MMAO: MMOS7_01690(fdhA) MMOS7_14050(fdhA)
MMAD: MMJJ_09470(fdhF_2) MMJJ_15440(fdhA2)
MAE: Maeo_0578
MTH: MTH_1140
MMG: MTBMA_c15230(fdhA2)
METE: tca_01096
MST: Msp_0640(fdhA)
MRU: mru_0333(fdhA1) mru_2074(fdhA2)
MEB: Abm4_0131(fdhA) Abm4_0855(fdhA2)
MMIL: sm9_1350(flpA) sm9_2183(fdhA)
MEYE: TL18_01670
METH: MBMB1_0104(fdhA)
MFC: BRM9_0168(fdhA)
MFI: DSM1535_1486(fdhA)
MCUB: MCBB_2028(fdhA)
MKA: MK0321
FPL: Ferp_0094
TAC: Ta0045
TVO: TVG0003442(TVG0003442)
FAI: FAD_1471
ABI: Aboo_0808
PYN: PNA2_1925
PYS: Py04_1234
TKO: TK2076
TGA: TGAM_0065(mhy2A) TGAM_0249(fdh1A) TGAM_0631(fdhA)
TSI: TSIB_0067
PPAC: PAP_03230
MBAR: MSBR2_2855
MMAC: MSMAC_2582
METM: MSMTP_1177
MHOR: MSHOH_1794
MPY: Mpsy_2944
MCJ: MCON_2237(fdhA)
MBG: BN140_0842(fdhA) BN140_1327(fdhA1) BN140_1329(fdhA2) BN140_2198(fdhA3)
MEMA: MMAB1_1106(fdhA) MMAB1_1689(fdhA) MMAB1_2914(fdhA)
MBN: Mboo_0923
MPD: MCP_1570(fdhA-1) MCP_2407(fdhA-2)
MEZ: Mtc_2125(fdhA)
RCI: RCIX1628(fdhA-1) RCIX2373(fdhA-2) RCIX2378(fdhA-3) RRC251(fdhA-4)
HHB: Hhub_2705(fdhA)
HALH: HTSR_1736(fdhA) HTSR_1740(fdhA2)
HHSR: HSR6_1802(fdoG2) HSR6_1806(fdoG3)
HHI: HAH_5041(fdhA)
NMO: Nmlp_2714(fdhA)
HLA: Hlac_1238
HALQ: Hrr1229_013155(fdhF)
HALU: HUG12_20610(fdhF)
HDF: AArcSl_0465(fdoG) AArcSl_1489(fdoG2)
HTU: Htur_0685
HALY: HYG82_00570(fdhF)
IHO: Igni_1101
IIS: EYM_07315
MSE: Msed_1457
AHO: Ahos_2012
STEP: IC006_0501
VDI: Vdis_2449
TPE: Tpen_0190
 » show all
Reference
  Authors
Lupa B, Hendrickson EL, Leigh JA, Whitman WB
  Title
Formate-dependent H2 production by the mesophilic methanogen Methanococcus maripaludis.
  Journal
Appl Environ Microbiol 74:6584-90 (2008)
DOI:10.1128/AEM.01455-08
Reference
  Authors
Costa KC, Lie TJ, Xia Q, Leigh JA
  Title
VhuD facilitates electron flow from H2 or formate to heterodisulfide reductase in Methanococcus maripaludis.
  Journal
J Bacteriol 195:5160-5 (2013)
DOI:10.1128/JB.00895-13
LinkDB

KEGG   ORTHOLOGY: K00125
Entry
K00125                      KO                                     

Name
fdhB
Definition
formate dehydrogenase (coenzyme F420) beta subunit [EC:1.17.98.3 1.8.98.6]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00356  Methanogenesis, methanol => methane
M00357  Methanogenesis, acetate => methane
M00563  Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00567  Methanogenesis, CO2 => methane
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K00125  fdhB; formate dehydrogenase (coenzyme F420) beta subunit
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.98  With other, known, physiological acceptors
    1.8.98.6  formate:CoB-CoM heterodisulfide,ferredoxin reductase
     K00125  fdhB; formate dehydrogenase (coenzyme F420) beta subunit
  1.17  Acting on CH or CH2 groups
   1.17.98  With other, known, physiological acceptors
    1.17.98.3  formate dehydrogenase (coenzyme F420)
     K00125  fdhB; formate dehydrogenase (coenzyme F420) beta subunit
Other DBs
RN: R10797 R11944
COG: COG1035 COG1139
GO: 0043794
Genes
TMB: Thimo_0255
SLAC: SKTS_06260
DDE: Dde_1211 Dde_3528
DDN: DND132_1390
DMA: DMR_01940
DSA: Desal_0598
DHY: DESAM_21328
DGG: DGI_1052(floxC)
DFL: DFE_0758 DFE_2489
DCB: C3Y92_00575
DAS: Daes_0781
DPI: BN4_11862
DBA: Dbac_2346
DRT: Dret_0419
DAL: Dalk_5062
DAT: HRM2_22740(fdhB6)
DBR: Deba_2134
BLAG: BLTE_14910
RCH: RUM_11000
RUM: CK1_05080
SWO: Swol_0400
SALQ: SYNTR_0266
PTH: PTH_1407(RnfC)
DAU: Daud_0567
SGY: Sgly_1898
HMO: HM1_2010
CTHM: CFE_1626
CHY: CHY_0932
ADG: Adeg_1331
MJA: MJ_0005
MMP: MMP0139(fdhB) MMP1297(fdhB)
MMAK: MMKA1_01440(fdhB) MMKA1_15220(fdhB)
MMAO: MMOS7_01700(fdhB) MMOS7_14040(fdhB)
MMAD: MMJJ_09460 MMJJ_15460(fdhB1)
MAE: Maeo_0577
MTH: MTH_1139
MMG: MTBMA_c15220(fdhB)
MWO: MWSIV6_0698(fdhB1) MWSIV6_1531(fdhB3)
METE: tca_01095
MST: Msp_0639(fdhB)
MRU: mru_0334(fdhB1) mru_2075(fdhB2)
MEB: Abm4_0132(fdhB) Abm4_0854(fdhB2)
MMIL: sm9_1349(flpB) sm9_2182(fdhB)
METH: MBMB1_0103(fdhB)
MFC: BRM9_0167(fdhB)
MFI: DSM1535_1485(fdhB)
MCUB: MCBB_2029(fdhB1) MCBB_2031(fdhB3)
MKA: MK0322
ABI: Aboo_0980
MBAR: MSBR2_2854
MMAC: MSMAC_2581
MHOR: MSHOH_1795
MPY: Mpsy_2943
MHI: Mhar_0324
MBG: BN140_0841(fdhB) BN140_1328(fdhB1) BN140_1330(fdhB2) BN140_2197(fdhB3)
MEMA: MMAB1_1105(fdhB) MMAB1_1690(fdhB) MMAB1_2913(fdhB)
MBN: Mboo_0924
MPD: MCP_1569(fdhB-1) MCP_2406(fdhB-2)
MEZ: Mtc_2124(fdhB)
RCI: RCIX1630(fdhB-1) RCIX2372(fdhB-2) RCIX2376(fdhB-3) RRC252(fdhB-4)
PSYT: DSAG12_02784(fdhB_1) DSAG12_03719(fdhB_2)
 » show all
Reference
  Authors
Lupa B, Hendrickson EL, Leigh JA, Whitman WB
  Title
Formate-dependent H2 production by the mesophilic methanogen Methanococcus maripaludis.
  Journal
Appl Environ Microbiol 74:6584-90 (2008)
DOI:10.1128/AEM.01455-08
Reference
  Authors
Costa KC, Lie TJ, Xia Q, Leigh JA
  Title
VhuD facilitates electron flow from H2 or formate to heterodisulfide reductase in Methanococcus maripaludis.
  Journal
J Bacteriol 195:5160-5 (2013)
DOI:10.1128/JB.00895-13
LinkDB

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