KEGG   ORTHOLOGY: K23006Help
Entry
K23006                      KO                                     

Name
FAD3
Definition
omega-3 fatty acid desaturase (Delta-15 desaturase) [EC:1.14.19.-]
Pathway
ko01040  Biosynthesis of unsaturated fatty acids
ko01100  Metabolic pathways
ko01212  Fatty acid metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   01040 Biosynthesis of unsaturated fatty acids
    K23006  FAD3; omega-3 fatty acid desaturase (Delta-15 desaturase)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.-  
     K23006  FAD3; omega-3 fatty acid desaturase (Delta-15 desaturase)
BRITE hierarchy
Other DBs
RN: R12205
GO: 0042389
Genes
KLA: KLLA0_B00473g
KMX: KLMA_40623
LTH: KLTH0E10912g
PPA: PAS_chr4_0743
DHA: DEHA2E14542g
PIC: PICST_81126
PGU: PGUG_03640
SPAA: SPAPADRAFT_61534
LEL: LELG_00296
CAL: CAALFM_C113070CA(FAD3)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kainou K, Kamisaka Y, Kimura K, Uemura H
  Title
Isolation of Delta12 and omega3-fatty acid desaturase genes from the yeast Kluyveromyces lactis and their heterologous expression to produce linoleic and alpha-linolenic acids in Saccharomyces cerevisiae.
  Journal
Yeast 23:605-12 (2006)
DOI:10.1002/yea.1378
  Sequence
Reference
  Authors
Murayama SY, Negishi Y, Umeyama T, Kaneko A, Oura T, Niimi M, Ubukata K, Kajiwara S
  Title
Construction and functional analysis of fatty acid desaturase gene disruptants in Candida albicans.
  Journal
Microbiology 152:1551-8 (2006)
DOI:10.1099/mic.0.28751-0
  Sequence
LinkDB All DBs

KEGG   ORTHOLOGY: K22993Help
Entry
K22993                      KO                                     

Name
K22993
Definition
bifunctional Delta-12/omega-3 fatty acid desaturase [EC:1.14.19.6 1.14.19.-]
Pathway
ko01040  Biosynthesis of unsaturated fatty acids
ko01100  Metabolic pathways
ko01212  Fatty acid metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   01040 Biosynthesis of unsaturated fatty acids
    K22993  K22993; bifunctional Delta-12/omega-3 fatty acid desaturase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.6  acyl-CoA (9+3)-desaturase
     K22993  K22993; bifunctional Delta-12/omega-3 fatty acid desaturase
    1.14.19.-  
     K22993  K22993; bifunctional Delta-12/omega-3 fatty acid desaturase
BRITE hierarchy
Other DBs
RN: R12205
GO: 0045485 0042389
Genes
NCR: NCU09497
NTE: NEUTE1DRAFT116751(NEUTE1DRAFT_116751)
SMP: SMAC_07882
PAN: PODANSg2430
MTM: MYCTH_50837
CTHR: CTHT_0071750
MGR: MGG_08474
TMN: UCRPA7_3220
SSCK: SPSK_07620
FGR: FGSG_07890
CMT: CCM_09560
ANI: AN7204.2
ANG: ANI_1_962124(An14g06980)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Damude HG, Zhang H, Farrall L, Ripp KG, Tomb JF, Hollerbach D, Yadav NS
  Title
Identification of bifunctional delta12/omega3 fatty acid desaturases for improving the ratio of omega3 to omega6 fatty acids in microbes and plants.
  Journal
Proc Natl Acad Sci U S A 103:9446-51 (2006)
DOI:10.1073/pnas.0511079103
  Sequence
LinkDB All DBs

KEGG   REACTION: R12205Help
Entry
R12205                      Reaction                               

Name
linoleoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (15,16 cis-dehydrogenating)
Definition
Linoleoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (9Z,12Z,15Z)-Octadecatrienoyl-CoA + 2 Ferricytochrome b5 + 2 H2O
Equation
C02050 + 2 C00999 + C00007 + 2 C00080 <=> C16162 + 2 C00996 + 2 C00001
Enzyme
1.14.19.-
Pathway
rn01040  Biosynthesis of unsaturated fatty acids
rn01212  Fatty acid metabolism
Orthology
K22993  bifunctional Delta-12/omega-3 fatty acid desaturase [EC:1.14.19.6 1.14.19.-]
K23006  omega-3 fatty acid desaturase (Delta-15 desaturase) [EC:1.14.19.-]
LinkDB All DBs

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