KEGG   ORTHOLOGY: K23146
Entry
K23146                      KO                                     

Name
HPD1
Definition
3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase [EC:1.1.1.31 1.1.1.59]
Pathway
ko00280  Valine, leucine and isoleucine degradation
ko00410  beta-Alanine metabolism
ko00640  Propanoate metabolism
ko01100  Metabolic pathways
ko01200  Carbon metabolism
Module
M00013  Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    K23146  HPD1; 3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    K23146  HPD1; 3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    K23146  HPD1; 3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.31  3-hydroxyisobutyrate dehydrogenase
     K23146  HPD1; 3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase
    1.1.1.59  3-hydroxypropionate dehydrogenase
     K23146  HPD1; 3-hydroxyisobutyrate/3-hydroxypropionate dehydrogenase
Other DBs
RN: R01608 R05066
COG: COG2084
GO: 0008442 0047565
Genes
DME: Dmel_CG15093(CG15093)
DER: 6547189
DSE: 6609855
DSI: Dsimw501_GD25359(Dsim_GD25359)
DYA: Dyak_GE13884
DSR: 110178468 110178492
DPO: Dpse_GA13484
DPE: 6591227
DMN: 108160705 117191284
DWI: 6651391
DAZ: 108615719
DNV: 108655096
DHE: 111604074
DVI: 6627203
MDE: 101898222
LCQ: 111682074
AAG: 5578900
AME: 551208
BIM: 100748925
BTER: 100650674
CCAL: 108631411
OBB: 114880595
SOC: 105199897
MPHA: 105829621
AEC: 105148657
ACEP: 105623652
PBAR: 105423914
HST: 105183984
DQU: 106751759
CFO: 105247857
LHU: 105675093
PGC: 109856102
OBO: 105278581
NVI: 100119485
CSOL: 105359007
MDL: 103570641
BMOR: 100174823(hibadh)
BMAN: 114245382
PMAC: 106707996
PRAP: 111001538
HAW: 110372073
TNL: 113494831
PXY: 105389772
BTAB: 109036117
ATH: AT4G20930
ALY: 9305992
CRB: 17879685
BRP: 103834215
BOE: 106331744
RSZ: 108819502
THJ: 104806251
CPAP: 110807635
CIT: 102613224
TCC: 18595071
GRA: 105793915
GAB: 108465045
DZI: 111275382
EGR: 104440683
VRA: 106775809
VAR: 108342905
VUN: 114188962
CCAJ: 109803365
CAM: 101500780
LJA: Lj6g3v1629990.1(Lj6g3v1629990.1)
ADU: 107483242
AIP: 107638855
LANG: 109334356
FVE: 101306412
RCN: 112166404
PPER: 18780443
PMUM: 103325239
PAVI: 110758641
MDM: 103435630
PXB: 103952367
CSV: 101210819
CMO: 103488390
MCHA: 111010940
CMAX: 111495162
CMOS: 111434338
CPEP: 111783548
RCU: 8265515
JCU: 105636845
HBR: 110650572
MESC: 110600137
POP: 7471688
PEU: 105136238
JRE: 109012874
VVI: 100242424
SLY: 101265687
SPEN: 107009454
SOT: 102599107
CANN: 107853316
NSY: 104211935
NTO: 104113587
NAU: 109234219
INI: 109174135
SIND: 105175798
OEU: 111368685
HAN: 110878751
LSV: 111878357
CCAV: 112512592
DCR: 108206577
BVG: 104901234
NNU: 104589227
OSA: 9268115
DOSA: Os06t0677400-01(Os06g0677400)
OBR: 102711538
BDI: 100838762
ATS: 109781405(LOC109781405)
SBI: 110431419
ZMA: 100283587
SITA: 101764065
PDA: 103713826
EGU: 105049084
MUS: 103999516
DCT: 110111413
PEQ: 110023183
AOF: 109822246
ATR: 18427315
PPP: 112279665
MNG: MNEG_6697
APRO: F751_4388
PIC: PICST_35865(HIB1)
CAL: CAALFM_C602890CA(HPD1)
NCR: NCU06559
NTE: NEUTE1DRAFT145029(NEUTE1DRAFT_145029)
MGR: MGG_01687
SSCK: SPSK_05342
MAW: MAC_01431
MAJ: MAA_07047
CMT: CCM_00032
ANI: AN0593.2
ANG: ANI_1_1106074(An08g07890)
ABE: ARB_07874
TVE: TRV_06555
ABP: AGABI1DRAFT116631(AGABI1DRAFT_116631)
ABV: AGABI2DRAFT196100(AGABI2DRAFT_196100)
 » show all
Reference
  Authors
Otzen C, Bardl B, Jacobsen ID, Nett M, Brock M
  Title
Candida albicans utilizes a modified beta-oxidation pathway for the degradation of toxic propionyl-CoA.
  Journal
J Biol Chem 289:8151-69 (2014)
DOI:10.1074/jbc.M113.517672
  Sequence
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